New tricks for old dogs: unexpected roles for cell cycle regulators revealed using animal models Academic Article uri icon

abstract

  • Studies in animal models have revealed many surprises regarding the importance of key cell cycle regulators during animal development and homeostasis, underscoring the plasticity and redundancy of cell cycle circuitry within a whole-animal context. Moreover, checkpoint regulators, which are not essential for viability in yeast and cultured cells, play important roles in cell cycle control during development.

publication date

  • December 2004