A Synthesis of 1-Methoxyisoquinoline-3,4-Diamine and Some Derived Imidazo[4,5-C]Isoquinolines Academic Article uri icon

abstract

  • A convenient synthesis of 1-methoxyisoquinoline-3,4-diamine is described. From this, one-carbon bridging units were used to prepare the angular imidazo [4,5-c] isoquinoline system containing 2-aryl, 2-thio and 2-amino substituents . From the latter two, further ring formation between substituent and imidazo nitrogen was investigated.

publication date

  • 1986