Fused Isoquinoline Systems From Reactions of an Iminoisocoumarin With Nitrogen Nucleophiles Academic Article uri icon


  • Some reactions of 1-acetylimino-3-methyl-1H-2-benzopyran-4-carbonitrile with nitrogen nucleophiles are reported. This is a versatile intermediate and leads to isoquino [1,2-b] quinazoline (with methyl anthranilate ), [1,2,4] triazolo [5,1-a] isoquinoline (with hydrazine), imidazo [2,1-a] isoquinoline (with glycine ethyl ester), benzimidazo [2,1-a] isoqinoline (with o-phenylenediamine) and 1,3,5-triacine (with acetamidine ) systems.

publication date

  • 1996