Synthetic uses of the sequential ring positional reactivity in Pyridin-3-ol and derivatives Academic Article uri icon


  • A series of ring-substituted pyridin-3-ols has been prepared. The key to the scheme is the introduction of a bromo group to a specific ring position as a temporary blocking agent. As well as hydrogenolysis of the bromo function, nucleophilic displacement has also been investigated.

publication date

  • 1981