Do cytosolic factors prevent promiscuity at the membrane surface? Academic Article uri icon

abstract

  • From the point of view of a preprotein, escaping from the cytosol into a specific organelle must seem an arduous, almost impossible task. How is it that preproteins resist the temptation to fold prematurely, to avoid the multiple membrane surfaces in the cell, and manage instead to enter only the translocation apparatus of a single organelle?

publication date

  • August 23, 1993