selected publications
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academic article
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Davalos Salas MMontgomery MKReehorst CNightingale RNg IAnderton HAl-Obaidi SLesmana AScott CIoannidis PKalra HKeerthikumar STogel LRigopoulos AGong SWilliams DSYoganantharaja PBell-Anderson KMathivanan SGibert YHiebert SScott AMWatt MJMariadason JM. Deletion of intestinal Hdac3 remodels the lipidome of enterocytes and protects mice from diet-induced obesity.
Nature Communications.
10.
2019
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Burvenich IJGParakh SLee F-TGuo NLiu ZGan HKRigopoulos AO'Keefe GJGong SJGoh YWTochon-Danguy HScott FEKotsuma MHirotani KSenaldi GScott AM. Molecular imaging of T cell co-regulator factor B7-H3 with Zr-89-DS-5573a.
Theranostics.
8:4199-4209.
2018
Full text if available -
Burvenich IJGLee F-TO'Keefe GJMakris DCao DGong SRigopoulos AAllan LCBrechbiel MWLiu ZRamsland PAScott AM. Engineering anti-Lewis-Y hu3S193 antibodies with improved therapeutic ratio for radioimmunotherapy of epithelial cancers.
EJNMMI Research.
6:1-13.
2016
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Burvenich IJGLee F-TGuo NGan HKRigopoulos AParslow ACO'Keefe GJGong SJTochon-Danguy HRudd SEDormelly PSKotsuma MOhtsuka TSenaldi GScott AM. In vitro and in vivo evaluation of 89Zr-DS-8273a as a theranostic for anti-death receptor 5 therapy.
Theranostics.
6:2225-2234.
2016
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Lee FTBurvenich IJGGuo NKocovski PTochon-Danguy HAckermann UO'Keefe GJGong SRigopoulos ALiu ZGan HKScott AM. L-Tyrosine Confers Residualizing Properties to a D-Amino Acid-Rich Residualizing Peptide for Radioiodination of Internalizing Antibodies.
Molecular Imaging.
15:1-9.
2016
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Burvenich IJGParakh SGan HKLee F-TGuo NRigopoulos ALee S-TGong SO'Keefe GJTochon-Danguy HKotsuma MHasegawa JSenaldi GScott AM. Molecular Imaging and Quantitation of EphA2 Expression in Xenograft Models with Zr-89-DS-8895a.
Journal of Nuclear Medicine.
57:974-980.
2016
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Chang JHLim Joon DDavis IDLee STHiew CYEsler SGong SJWada MClouston DO'Sullivan RGoh YPBolton DScott AMKhoo V. Comparison of [<sup>11</sup>C]choline positron emission tomography with T2- and diffusion-weighted magnetic resonance imaging for delineating malignant intraprostatic lesions.
International Journal of Radiation: Oncology - Biology - Physics.
92:438-445.
2015
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Glikmann-Johnston YSaling MMChen JO'Keefe GGong STochon-Danguy HMulligan RReutens DC. Hippocampal 5-HT 1A receptor binding is related to object–location memory in humans.
Brain Structure and Function.
220:559-570.
2015
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Greening DWLee STJi HSimpson RJRigopoulos AMurone CFang CGong SO'Keefe GScott AM. Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathways.
Oncotarget.
6:38166-38180.
2015
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Ciprotti MTebbutt NCLee F-TLee S-TGan HKMcKee DCO'Keefe GJGong SJChong GHopkins WChappell BScott FEBrechbiel MWTse ANJansen MMatsumura MKotsuma MWatanabe RVenhaus RBeckman RAGreenberg JScott AM. Phase I Imaging and Pharmacodynamic Trial of CS-1008 in Patients With Metastatic Colorectal Cancer.
Journal of Clinical Oncology.
33:2609-2616.
2015
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Chang JHLim Joon DLee STHiew CYEsler SGong SJWada MClouston DO'Sullivan RGoh YPTochon-Danguy HChan JGBolton DScott AMKhoo VDavis ID. Diffusion-weighted MRI, 11C-choline PET and 18F- fluorodeoxyglucose PET for predicting the Gleason score in prostate carcinoma.
European Radiology.
24:715-722.
2014
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Chang JHWada MAnderson NJLim Joon DLee STGong SJGunawardana DHSachinidis JO'Keefe GGan HKKhoo VScott AM. Hypoxia-targeted radiotherapy dose painting for head and neck cancer using 18F-FMISO PET: A biological modeling study.
Acta Oncologica.
52:1723-1729.
2013
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Burvenich IJGLee FTCartwright GAO'Keefe GJMakris DCao DGong SChueh ACMariadason JMBrechbiel MWBeckman RAFujiwara KVon Roemeling RScott AM. Molecular imaging of death receptor 5 occupancy and saturation kinetics in vivo by humanized monoclonal antibody CS-1008.
Clinical Cancer Research.
19:5984-5993.
2013
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Chang JHLim Joon DLee STGong SJAnderson NJScott AMDavis IDClouston DBolton DHamilton CSKhoo V. Intensity modulated radiation therapy dose painting for localized prostate cancer using C-choline positron emission tomography scans.
International Journal of Radiation: Oncology - Biology - Physics.
83:e692-e697.
2012
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Ly JVRowe CCVillemagne VLZavala JAMa HSahathevan RO'Keefe GGong SJGunawan RChurilov LSaunder TAckerman UTochon-Danguy HDonnan GA. Subacute ischemic stroke is associated with focal 11C PiB positron emission tomography retention but not with global neocortical aβ deposition.
Stroke.
43:1341-1346.
2012
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Fodero-Tavoletti MTOkamura NFurumoto SMulligan RSConnor ARMcLean CACao DRigopoulos ACartwright GAO'Keefe GGong SAdlard PABarnham KJRowe CCMasters CLKudo YCappai RYanai KVillemagne VL. 18F-THK523: A novel in vivo tau imaging ligand for Alzheimer's disease.
Brain: a journal of neurology.
134:1089-1100.
2011
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Chang JHJoon DLLee STGong SJScott AMDavis IDClouston DBolton DHamilton CSKhoo V. Histopathological correlation of 11C-choline PET scans for target volume definition in radical prostate radiotherapy.
Radiotherapy and Oncology.
99:187-192.
2011
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Villemagne VLOkamura NPejoska SDrago JMulligan RSChételat GAckermann UO'Keefe GJones GGong STochon-Danguy HKung HFMasters CLSkovronsky DMRowe CC. In vivo assessment of vesicular monoamine transporter type 2 in dementia with lewy bodies and alzheimer disease.
Archives of Neurology.
68:905-912.
2011
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Ly JVRowe CCVillemagne VLZavala JAMa HO'Keefe GGong SJGunawan RChurilov LSaunder TAckerman UTochon-Danguy HDonnan GA. Cerebral β-amyloid detected by Pittsburgh compound B positron emission topography predisposes to recombinant tissue plasminogen activator-related hemorrhage.
Annals of Neurology.
68:959-962.
2010
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Ly JVDonnan GAVillemagne VLZavala JAMa HO'Keefe GGong SJGunawan RMSaunder TAckerman UTochon-Danguy HChurilov LPhan TGRowe CC. 11C-PIB binding is increased in patients with cerebral amyloid angiopathy-related hemorrhage.
Neurology.
74:487-493.
2010
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O'Keefe GJSaunder THNg SAckerman UTochon-Danguy HJChan JGGong SDyrks TLindemann SHoll GDinkelborg LVillemagne VRowe CC. Radiation Dosimetry of -Amyloid Tracers 11C-PiB and 18F-BAY94-9172.
Journal of Nuclear Medicine.
50:309-315.
2009
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He JO'Keefe GJGong SJJones GSaunder TScott AMGeso M. A Novel Method for Respiratory Motion Gated With Geometric Sensitivity of the Scanner in 3D PET.
IEEE Transactions on Nuclear Science.
55:2557-2565.
2008
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Fedi MBerkovic SFScheffer IEO'Keefe GMarini CMulligan RGong STochon-Danguy HReutens DC. Reduced striatal D1 receptor binding in autosomal dominant nocturnal frontal lobe epilepsy.
Neurology.
71:795-798.
2008
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Ellis JRVillemagne VLNathan PJMulligan RSGong SJChan JGSachinidis JO’Keefe GJPathmaraj KWesnes KA. Relationship between nicotinic receptors and cognitive function in early Alzheimer’s disease: A 2-[18F]fluoro-A-85380 PET study.
Neurobiology of Learning and Memory.
90:404-412.
2008
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He JO'Keefe GJJones GSaunder TGong SJGeso MScott AM. Evaluation of Geometrical Sensitivity for Respiratory Motion Gating by GATE and NCAT Simulation.
Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings.
2007:4165-4168.
2007
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He JO'Keefe GJones GSaunder TGong SScott AGeso M. SU-FF-I-106: Simulation of Respiratory Motion Gating Using GATE and NCAT.
Medical Physics.
34:2362-2362.
2007
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Rowe CCNg SAckermann UGong SJPike KSavage GCowie TFDickinson KLMaruff PDarby DSmith CWoodward MMerory JTochon-Danguy HO'Keefe GKlunk WEMathis CAPrice JCMasters CLVillemagne VL. Imaging -amyloid burden in aging and dementia.
Neurology.
68:1718-1725.
2007
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Ng SVillemagne VLBerlangieri SLee S-TCherk MGong SJAckermann USaunder TTochon-Danguy HJones GSmith CO'Keefe GMasters CLRowe CC. Visual Assessment Versus Quantitative Assessment of 11C-PIB PET and 18F-FDG PET for Detection of Alzheimer's Disease.
Journal of Nuclear Medicine.
48:547-552.
2007
Full text if available
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Davalos Salas MMontgomery MKReehorst CNightingale RNg IAnderton HAl-Obaidi SLesmana AScott CIoannidis PKalra HKeerthikumar STogel LRigopoulos AGong SWilliams DSYoganantharaja PBell-Anderson KMathivanan SGibert YHiebert SScott AMWatt MJMariadason JM. Deletion of intestinal Hdac3 remodels the lipidome of enterocytes and protects mice from diet-induced obesity.
Nature Communications.
10.
2019
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conference paper
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Burvenich IJGParakh SLee F-TGuo NLiu ZGan HKRigopoulos AO'Keefe GJGong SJGoh YWTochon-Danguy HScott FEKotsuma MHirotani KSenaldi GScott AM. Molecular imaging of T cell co-regulator factor B7-H3 with 89Zr-DS-5573a.
Theranostics.
4199-4209.
2018
Full text if available -
Burvenich IParakh SBurvenich JGLee F-TGuo NGan HKRigopoulos AO'Keefe GJGong STochon-Danguy HKotsuma MHirotani KSenaldi GScott AM. MOLECULAR IMAGING OF T-CELL CO-REGULATOR FACTOR B7-H3 WITH 89Zr-DS-5573A.
Internal Medicine Journal.
20-20.
2017
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Jianfeng HeO'Keefe GJAckerly TGong SJGeso M. Respiratory motion correction utilizing geometric sensitivity in 3D PET: A simulation study.
IEEE Nuclear Science Symposium Conference Record.
1220-1224.
2009
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He JO'Keefe GJJones GSaunder TGong SJGeso MScott AM. Evaluation of geometrical sensitivity for respiratory motion gating by GATE and NCAT simulation.
Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings.
4165-4168.
2007
Full text if available -
Jianfeng HeO'Keefe GJGong SJSaunder TJones GScott AMMoshi Geso. Investigation of respiratory motion gating with geometric sensitivity in Allegro PET.
IEEE Nuclear Science Symposium Conference Record.
4336-4344.
2007
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He JO'Keefe GJJones GSaunder TGong SJGeso MScott AM. The Application of GATE and NCAT to Respiratory Motion Simulation in Allegro PET.
IEEE Nuclear Science Symposium Conference Record.
2589-2593.
2006
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Gong SJO’Keefe GJRykers KMantle CGunawardana DHRolfo AWada MScott AM. PET/CT Rigid-Body Registration in Radiation Treatment Planning Settings: Phantom Validation and Strategy Investigation.
Lecture Notes in Computer Science.
222-229.
2006
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Gong SJO'Keefe GJScott AM. Comparison and Evaluation of PET/CT Image Registration.
Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings.
1599-1603.
2005
Full text if available
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Burvenich IJGParakh SLee F-TGuo NLiu ZGan HKRigopoulos AO'Keefe GJGong SJGoh YWTochon-Danguy HScott FEKotsuma MHirotani KSenaldi GScott AM. Molecular imaging of T cell co-regulator factor B7-H3 with 89Zr-DS-5573a.
Theranostics.
4199-4209.
2018
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erratum
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Greening DWLee STJi HSimpson RJRigopoulos AMurone CFang CGong SO’Keefe GScott AM. Correction: Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathways.
Oncotarget.
35497.
2016
Full text if available
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Greening DWLee STJi HSimpson RJRigopoulos AMurone CFang CGong SO’Keefe GScott AM. Correction: Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathways.
Oncotarget.
35497.
2016
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abstract
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Scott ABurvenich ILee FO'Keefe GMakris DCao DGong SRigopoulos AAllan LBrechbiel MLiu ZRamsland P. Engineering anti-Lewis-Y hu3S193 antibodies with improved therapeutic ratio for radioimmunotherapy of epithelial cancers.
Internal Medicine Journal.
19-19.
2016
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Scott ABurvenich ILee FO'Keefe GMakris DCao DGong SRigopoulos AAllan LBrechbiel MLiu ZRamsland P. Engineering anti-Lewis-Y hu3S193 antibodies with improved therapeutic ratio for radioimmunotherapy of epithelial cancers.
Internal Medicine Journal.
19-19.
2016