subject area of
- A novel achiral seco-cyclopropylpyrido[e]indolone (CPyI) analog of CC-1065 and the duocarmycins: Synthesis, DNA interactions, in vivo anticancer and anti-parasitic evaluation Academic Article
- Activation of DNA damage response pathways as a consequence of anthracycline-DNA adduct formation Academic Article
- Adriamycin-induced DNA Adducts Inhibit the DNA Interactions of Transcription Factors and RNA Polymerase Academic Article
- Adriamycin-induced inhibition of mitochondrial-encoded polypeptides as a model system for the identification of hotspots for DNA-damaging agents Academic Article
- Application of analytical and semi-preparative high-performance liquid chromatography to anthracyclines and bis-anthracycline derivatives Academic Article
- Barminomycin functions as a potent pre-activated analogue of Adriamycin Academic Article
- Characterisation of the novel apoptotic and therapeutic activities of the histone deacetylase inhibitor romidepsin Academic Article
- Comprehensive echocardiographic detection of treatment-related cardiac dysfunction in adult survivors of childhood cancer Academic Article
- CpG methylation potentiates pixantrone and doxorubicin-induced DNA damage and is a marker of drug sensitivity Academic Article
- Deglycosylated bleomycin induces apoptosis in lymphoma cell via c-jun NH2-terminal kinase but not reactive oxygen species Academic Article
- Deletion of Ribosomal S6 Kinases Does Not Attenuate Pathological, Physiological, or Insulin-Like Growth Factor 1 Receptor-Phosphoinositide 3-Kinase-Induced Cardiac Hypertrophy Academic Article
- Detection of Adriamycin-DNA adducts by accelerator mass spectrometry at clinically relevant Adriamycin concentrations Academic Article
- Development of Pluronic Micelle-Encapsulated Doxorubicin and Formaldehyde-Releasing Prodrugs for Localized Anticancer Chemotherapy Academic Article
- Distinct contributions of hyperglycemia and high-fat feeding in metabolic syndrome-induced neuroinflammation Academic Article
- Doxorubicin-DNA Adducts Induce a Non-Topoisomerase II–Mediated Form of Cell Death Academic Article
- Drug-induced inactivation or gene silencing of class I histone deacetylases suppresses ovarian cancer cell growth: Implications for therapy Academic Article
- Effect of filgrastim on the pharmacokinetics of MX2 hydrochloride in patients with advanced malignant disease Academic Article
- Fast atom bombardment mass spectrometry of some anthracycline and bisanthracycline derivatives Academic Article
- Fluorinated anthracyclines: Synthesis and biological activity Academic Article
- Inhibition of cathepsin proteases attenuates migration and sensitizes aggressive N-Myc amplified human neuroblastoma cells to doxorubicin Academic Article
- Multicenter Randomized Phase III Trial Comparing Protracted Venous Infusion (PVI) Fluorouracil (5-FU) With PVI 5-FU Plus Mitomycin in Inoperable Pancreatic Cancer Academic Article
- Pharmacokinetics and pharmacodynamics of MX2 hydrochloride in patients with advanced malignant disease Academic Article
- Phase I and pharmacokinetic study of KRN8602 alone and with filgrastim in patients with advanced cancer. Academic Article
- Potential Therapeutic Advantages of Doxorubicin when Activated by Formaldehyde to Function as a DNA Adduct-Forming Agent Academic Article
- Primary invasive cancer of the vagina: Outcome and complications of therapy Academic Article
- Protease-responsive prodrug with aggregation-induced emission probe for controlled drug delivery and drug release tracking in living cells Academic Article
- Sequence specificity of adriamycin-DNA adducts in human tumor cells Academic Article
- Specific Inhibition of the Eubacterial DNA Ligase by Arylamino Compounds Academic Article
- Structural requirements for the formation of anthracycline - DNA adducts Academic Article
- Synthesis of polyamine-linked bis-daunomycin hydrazones and their interaction with DNA Academic Article
- The BH3 mimetic compound, ABT-737, synergizes with a range of cytotoxic chemotherapy agents in chronic lymphocytic leukemia Academic Article
- The hydroxyl epimer of doxorubicin controls the rate of formation of cytotoxic anthracycline-DNA adducts Academic Article
- Time dependent response of daunorubicin on cytotoxicity, cell cycle and DNA repair in acute lymphoblastic leukaemia Academic Article
- Upregulation of P-glycoprotein in rat hepatoma ρ° cells: Implications for drug–DNA interactions Academic Article