Apoptosis

subject area of

(α/β+α)-Peptide Antagonists of BH3 Domain/Bcl-x L Recognition: Toward General Strategies for Foldamer-Based Inhibition of Protein−Protein Interactions Academic Article
2-Methoxyestradiol – a unique blend of activities generating a new class of anti-tumour/anti-inflammatory agents Academic Article
5-aminosalicylic acid in combination with nimesulide inhibits proliferation of colon carcinoma cells in vitro Academic Article
8 Apoptosis, haemopoiesis and leukaemogenesis Academic Article
A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs Academic Article
A Functional Yeast Survival Screen of Tumor-Derived cDNA Libraries Designed to Identify Anti-Apoptotic Mammalian Oncogenes Academic Article
A QCM-D and SAXS Study of the Interaction of Functionalised Lyotropic Liquid Crystalline Lipid Nanoparticles with siRNA Academic Article
A Structural Viral Mimic of Prosurvival Bcl-2: A Pivotal Role for Sequestering Proapoptotic Bax and Bak Academic Article
A T cell-specific knockout reveals an important role for protease-activated receptor 2 in lymphocyte development Academic Article
A cinderella caspase takes center stage Academic Article
A comparison of novel organoiridium(III) complexes and their ligands as a potential treatment for prostate cancer Academic Article
A dual functional AEE fluorogen as a mitochondrial-specific bioprobe and an effective photosensitizer for photodynamic therapy Academic Article
A minimum of two distinct heritable factors are required to explain correlation structures in proliferating lymphocytes Academic Article
A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma Academic Article
A novel Apaf-1-independent putative caspase-2 activation complex Academic Article
A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation Academic Article
A novel influenza A virus mitochondrial protein that induces cell death Academic Article
A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure Academic Article
ABT-737, proving to be a great tool even before it is proven in the clinic Academic Article
AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC Academic Article
ATF3 Repression of BCL-X L Determines Apoptotic Sensitivity to HDAC Inhibitors across Tumor Types Academic Article
Abnormal Nuclear Pore Formation Triggers Apoptosis in the Intestinal Epithelium of elys-Deficient Zebrafish Academic Article
Absence of caveolin-1 alters heat shock protein expression in spontaneous mammary tumors driven by Her-2/neu expression Academic Article
Activation of clinically used anthracyclines by the formaldehyde-releasing prodrug pivaloyloxymethyl butyrate Academic Article
Activation of physiological cell death mechanisms by a necrosis-causing agent Academic Article
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death Academic Article
Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner Academic Article
Alterations in the apoptotic machinery and their potential role in anticancer drug resistance Academic Article
Alternative oxidase: a target and regulator of stress responses Academic Article
Alternative splicing of Bim and Erk-mediated Bim EL phosphorylation are dispensable for hematopoietic homeostasis in vivo Academic Article
An Essential Role for the Caspase Dronc in Developmentally Programmed Cell Death in Drosophila Academic Article
An appointment with death,: 2013 Cold Spring Harbor Asia meeting 'Mechanisms and Functions of Non-Apoptotic Cell Death' Conference Paper
An evolutionary perspective on apoptosis Academic Article
An optimized method for establishing high purity murine CD8+ T cell cultures Academic Article
Analysis of FasL and TRAIL induced apoptosis pathways in glioma cells Academic Article
Analysis of candidate antagonists of IAP-mediated caspase inhibition using yeast reconstituted with the mammalian Apaf-1-activated apoptosis mechanism Academic Article
Analysis of the Role of bcl-2 in Apoptosis Academic Article
Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma Academic Article
Angiotensin II Type 2 Receptor Stimulation Initiated After Stroke Causes Neuroprotection in Conscious Rats Academic Article
Another twist in the on and off affair between cell suicide and inflammation Editorial Article
Anti-apoptotic potential of insect cellular and viral IAPs in mammalian cells Academic Article
Antifibrotic Activity of Bevacizumab on Human Tenon's Fibroblasts In Vitro Academic Article
Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die Academic Article
Apoptogenic factors released from mitochondria Academic Article
Apoptosis Initiated When BH3 Ligands Engage Multiple Bcl-2 Homologs, Not Bax or Bak Academic Article
Apoptosis Timeline Academic Article
Apoptosis and the immune system Academic Article
Apoptosis and toxicology—what relevance? Academic Article
Apoptosis genes and autoimmunity Academic Article
Apoptosis in schistosomes: toward novel targets for the treatment of schistosomiasis Academic Article
Apoptosis in the development and treatment of cancer Academic Article
Apoptosis induced in synchronized human immunodeficiency virus type 1-infected primary peripheral blood mononuclear cells is detected after the peak of CD4+ T-lymphocyte loss and is dependent on the tropism of the gp120 envelope glycoprotein Academic Article
Apoptosis inhibitor 5 is an endogenous inhibitor of caspase‐2 Academic Article
Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome Academic Article
Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax Academic Article
Apoptosis: A sticky business Academic Article
Apoptotic Mechanisms After Cerebral Ischemia Academic Article
Apoptotic Sensitivity of Colon Cancer Cells to Histone Deacetylase Inhibitors Is Mediated by an Sp1/Sp3-Activated Transcriptional Program Involving Immediate-Early Gene Induction Academic Article
Apoptotic cell clearance: basic biology and therapeutic potential Academic Article
Apoptotic pore formation is associated with in-plane insertion of Bak or Bax central helices into the mitochondrial outer membrane Academic Article
Apoptotic, necrotic, or fused tumor cells: An equivalent source of antigen for dendritic cell loading Academic Article
Ars Moriendi; the art of dying well - new insights into the molecular pathways of necroptotic cell death. Academic Article
Arsenic Trioxide Induces Apoptosis of Human Monocytes during Macrophagic Differentiation through Nuclear Factor- B-Related Survival Pathway Down-Regulation Academic Article
Ataxin-2 interacts with FUS and intermediate-length polyglutamine expansions enhance FUS-related pathology in amyotrophic lateral sclerosis Academic Article
Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists, 1994: HYPOTHESIS: APOPTOSIS CAUSED BY CYTOTOXINS REPRESENTS A DEFENSIVE RESPONSE THAT EVOLVED TO COMBAT INTRACELLULAR PATHOGENS Conference Paper
BAFF selectively enhances the survival of plasmablasts generated from human memory B cells Academic Article
BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis Academic Article
BAX-BAK1-independent LC3B lipidation by BH3 mimetics is unrelated to BH3 mimetic activity and has only minimal effects on autophagic flux Academic Article
BCL2 and related prosurvival proteins require BAK1 and BAX to affect autophagy Academic Article
BH3-Only proteins in health and disease Chapter
BH3-only proteins: a 20-year stock-take Academic Article
Bak apoptotic pores involve a flexible C-terminal region and juxtaposition of the C-terminal transmembrane domains Academic Article
Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis Academic Article
Bcl-2 Prevents Apoptosis Induced by Perforin and Granzyme B, but Not That Mediated by Whole Cytotoxic Lymphocytes Academic Article
Bcl-2 and thermotolerance cooperate in cell survival Academic Article
Bcl-2 family proteins: The sentinels of the mitochondrial apoptosis pathway Academic Article
Bcl-2 in Cell Cycle Regulation Academic Article
Bcl-2–regulated apoptosis and cytochrome c release can occur independently of both caspase-2 and caspase-9 Academic Article
Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax Academic Article
Bim Links ER Stress and Apoptosis in Cells Expressing Mutant SOD1 Associated with Amyotrophic Lateral Sclerosis Academic Article
Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic Academic Article
Bioenergetic differences selectively sensitize tumorigenic liver progenitor cells to a new gold(I) compound Academic Article
Biomarkers in inflammatory bowel diseases: Current status and proteomics identification strategies Academic Article
Blocking granule-mediated death by primary human NK cells requires both protection of mitochondria and inhibition of caspase activity Academic Article
Bone Morphogenetic Protein-7 Inhibits Telomerase Activity, Telomere Maintenance, and Cervical Tumor Growth Academic Article
Both leukaemic and normal peripheral B lymphoid cells are highly sensitive to the selective pharmacological inhibition of prosurvival Bcl-2 with ABT-199 Academic Article
Bovine lactoferrin regulates cell survival, apoptosis and inflammation in intestinal epithelial cells and preterm pig intestine Academic Article
Buffy, a Drosophila Bcl-2 protein, has anti-apoptotic and cell cycle inhibitory functions Academic Article
Butyrate-induced apoptotic cascade in colonic carcinoma cells: Modulation of the β-catenin-Tcf pathway and concordance with effects of sulindac and trichostatin A but not curcumin Academic Article
CD4 ⁺ T-cell deficiency in HIV patients responding to antiretroviral therapy is associated with increased expression of interferon-stimulated genes in CD4 ⁺ T cells Academic Article
CED-4—The Third Horseman of Apoptosis Academic Article
CREB-binding protein (CBP) regulates β-adrenoceptor (β-AR)−mediated apoptosis Academic Article
Calsenilin contributes to neuronal cell death in ischemic stroke Academic Article
Cancer and programmed cell death Conference Paper
Cardioprotection Induced by Adenosine A1 Receptor Agonists in a Cardiac Cell Ischemia Model Involves Cooperative Activation of Adenosine A2A and A2B Receptors by Endogenous Adenosine Academic Article
Cardioprotection from ischaemia–reperfusion injury by a novel flavonol that reduces activation of p38 MAPK Academic Article
Caspase-14: a new player in cytotrophoblast differentiation Academic Article
Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9 Academic Article
Caspase-2 is resistant to inhibition by inhibitor of apoptosis proteins (IAPs) and can activate caspase-7 Academic Article
Caspase-2: controversial killer or checkpoint controller? Academic Article
Caspase-8 Cleaves Histone Deacetylase 7 and Abolishes Its Transcription Repressor Function Academic Article
Caspase-8 levels affect necessity for mitochondrial amplification in death ligand-induced glioma cell apoptosis Academic Article
Caspases and apoptosis – biology and terminology Academic Article
Cell Death in Development Academic Article
Cell death regulation by the mammalian IAP antagonist Diablo/Smac Academic Article
Cell death: Shadow Baxing Academic Article
Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment Academic Article
Cellular Mechanisms of Risk and Transformation Conference Paper
Characterisation of the novel apoptotic and therapeutic activities of the histone deacetylase inhibitor romidepsin Academic Article
Characterization of sequence-dependent synergy between ZD1839 (‘Iressa’) and oxaliplatin Academic Article
Characterization of the Drosophila Caspase, DAMM Academic Article
Characterization of the ectromelia virus serpin, SPI-2 Academic Article
Chemical chaperone TUDCA prevents apoptosis and improves survival during polymicrobial sepsis in mice Academic Article
Chemo-sensitisation of HeLa cells to Etoposide by a Benzoxazine in the absence of DNA-PK inhibition Academic Article
Chemotherapy overcomes TRAIL-R4-mediated TRAIL resistance at the DISC level Academic Article
Chromatin Structure Following UV-Induced DNA Damage—Repair or Death? Academic Article
Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors. Academic Article
Cloning of Mouse RP-8 cDNA and Its Expression During Apoptosis of Lymphoid and Myeloid Cells Academic Article
Coenzyme Q10 attenuates diastolic dysfunction, cardiomyocyte hypertrophy and cardiac fibrosis in the db/db mouse model of type 2 diabetes Academic Article
Colonic cell proliferation, differentiation, and apoptosis Conference Paper
Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways Academic Article
Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer Academic Article
Conformational Changes in Bcl-2 Pro-survival Proteins Determine Their Capacity to Bind Ligands Academic Article
Conservation of baculovirus inhibitor of apoptosis repeat proteins (BIRPs) in viruses, nematodes, vertebrates and yeasts Academic Article
Control of Apoptosis in Hematopoietic Cells by the Bcl-2 Family of Proteins Conference Paper
Controlling TRAIL-mediated caspase-3 activation Academic Article
Conversion of Bim-BH3 from activator to inhibitor of Bak through structure-based design Academic Article
Cre transgene results in global attenuation of the cAMP/PKA pathway Academic Article
CrmA expression in T lymphocytes of transgenic mice inhibits CD95 (Fas/APO-1)-transduced apoptosis, but does not cause lymphadenopathy or autoimmune disease Academic Article
Crystal structure of ABT-737 complexed with Bcl-xL: implications for selectivity of antagonists of the Bcl-2 family Academic Article
Cyclic-AMP-dependent protein kinase A regulates apoptosis by stabilizing the BH3-only protein Bim Academic Article
Cycloheximide can induce Bax/Bak dependent myeloid cell death independently of multiple BH3-only proteins Academic Article
Cytoplasmic p53 is not required for PUMA-induced apoptosis Academic Article
Cytotoxic T lymphocyte–induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis Academic Article
DR5 and caspase-8 are dispensable in ER stress-induced apoptosis Academic Article
Death in the snow: report on Keystone Conference on ‘Apoptosis and Programmed Cell Death’ at Breckenridge, CO, April 6–11th 1999 Conference Paper
Death to flies: Drosophila as a model system to study programmed cell death Academic Article
Debcl, a Proapoptotic Bcl-2 Homologue, Is a Component of the Drosophila melanogaster Cell Death Machinery Academic Article
Deerpox Virus Encodes an Inhibitor of Apoptosis That Regulates Bak and Bax Academic Article
Deglycosylated bleomycin induces apoptosis in lymphoma cell via c-jun NH2-terminal kinase but not reactive oxygen species Academic Article
Destruction of tumor vasculature and abated tumor growth upon VEGF blockade is driven by proapoptotic protein Bim in endothelial cells Academic Article
Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance Academic Article
Diabetic cardiomyopathy: Mechanisms and new treatment strategies targeting antioxidant signaling pathways Academic Article
Diablo Promotes Apoptosis by Removing Miha/Xiap from Processed Caspase 9 Academic Article
Diagnostic and Prognostic Potential of Extracellular Vesicles in Peripheral Blood Academic Article
Differential Inhibition of TRAIL-Mediated DR5-DISC Formation by Decoy Receptors 1 and 2 Academic Article
Differential Regulation of Gastric Tumor Growth by Cytokines That Signal Exclusively Through the Coreceptor gp130 Academic Article
Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Ligands Allows Complementary Apoptotic Function Academic Article
Differential regulation of Nedd4 ubiquitin ligases and their adaptor protein Ndfip1 in a rat model of ischemic stroke Academic Article
Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP Academic Article
Direct visualization of Bcl-2 family protein interactions using live cell fluorescent protein redistribution assays Academic Article
Disassembly of dying cells in diverse organisms Academic Article
Disassembly of the Dying: Mechanisms and Functions Academic Article
Discordant Regulation of Granzyme H and Granzyme B Expression in Human Lymphocytes Academic Article
Discovery and molecular characterization of a Bcl-2-regulated cell death pathway in schistosomes Academic Article
Discovery of potent and selective benzothiazole hydrazone inhibitors of Bcl-XL Academic Article
Dissection of Protease-Activated Receptor-1-Dependent and -Independent Responses to Thrombin in Skeletal Myoblasts Academic Article
Dissociation of Pentameric to Monomeric C-Reactive Protein on Activated Platelets Localizes Inflammation to Atherosclerotic Plaques Academic Article
Dissociation of staurosporine-induced apoptosis from G2-M arrest in SW620 human colonic carcinoma cells: Initiation of the apoptotic cascade is associated with elevation of the mitochondrial membrane potential (Δψ(m)) Academic Article
Disturbed oligodendrocyte development and recovery from hypomyelination in a c-myc transgenic mouse mutant Academic Article
Divergent phenotypic patterns and commitment to apoptosis of Caco-2 cells during spontaneous and butyrate-induced differentiation Academic Article
Doxorubicin-DNA Adducts Induce a Non-Topoisomerase II–Mediated Form of Cell Death Academic Article
Dual inhibition of BCL-XL and MCL-1 is required to induce tumour regression in lung squamous cell carcinomas sensitive to FGFR inhibition Academic Article
E2F7 Can Regulate Proliferation, Differentiation, and Apoptotic Responses in Human Keratinocytes: Implications for Cutaneous Squamous Cell Carcinoma Formation Academic Article
ER Stress Triggers Apoptosis by Activating BH3-Only Protein Bim Academic Article
ER Stress and UPR in Familial Amyotrophic Lateral Sclerosis Academic Article
ERp57 is protective against mutant SOD1-induced cellular pathology in amyotrophic lateral sclerosis Academic Article
Early origins of heart disease: Low birth weight and determinants of cardiomyocyte endowment Academic Article
Early work on the function of Bcl-2, an interview with David Vaux Academic Article
Effect of immunosuppressive agents on hepatocyte apoptosis post-liver transplantation Academic Article
Effects of Fe3O4 Magnetic Nanoparticles on A549 Cells Academic Article
Effects of viral inhibitors of apoptosis in models of mammalian cell death. Academic Article
Enantioselective Synthesis of Ferrocenyl Nucleoside Analogues with Apoptosis-Inducing Activity Academic Article
Endogenous bcl-2 is not required for the development of E -myc induced B-cell lymphoma Academic Article
Entamoeba histolytica: Target Cells Killed by Trophozoites Undergo DNA Fragmentation Which Is Not Blocked by Bcl-2 Academic Article
Erratum: BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes Academic Article
EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation Academic Article
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 Academic Article
Establishment of primary cultures of rat olfactory bulb under serum-free conditions for studies of cellular injury Academic Article
Evidence for a detrimental role of TLR8 in ischemic stroke Academic Article
Evidence of the TNF-α system in the human achilles tendon: Expression of TNF-α and TNF receptor at both protein and mRNA levels in the tenocytes Academic Article
Evolutionary divergence of the necroptosis effector MLKL Academic Article
Ex vivo pediatric brain tumors express Fas (CD95) and FasL (CD95L) and are resistant to apoptosis induction Academic Article
Excessive Apoptosis in Patellar Tendinopathy in Athletes Academic Article
Executioner caspases and CAD are essential for mutagenesis induced by TRAIL or vincristine Academic Article
Exosomes: Extracellular organelles important in intercellular communication Academic Article
Expanded Granulocyte/Monocyte Compartment in Myeloid-Specific Triple FoxO Knockout Increases Oxidative Stress and Accelerates Atherosclerosis in Mice Academic Article
Experimental in vivo sepsis models to monitor immune cell apoptosis and survival in laboratory mice Chapter
Expression of candidate cell death genes in cell lines during apoptosis Academic Article
Expression of secreted frizzled-related protein 4 in the primate placenta Academic Article
Expression of the Vaccinia Virus Antiapoptotic F1 Protein Is Blocked by Protein Kinase R in the Absence of the Viral E3 Protein Academic Article
Extracellular wildtype and mutant SOD1 induces ER–Golgi pathology characteristic of amyotrophic lateral sclerosis in neuronal cells Academic Article
FOXP3 over-expression inhibits melanoma tumorigenesis via effects on proliferation and apoptosis. Academic Article
Fatal Hepatitis Mediated by Tumor Necrosis Factor TNFα Requires Caspase-8 and Involves the BH3-Only Proteins Bid and Bim Academic Article
Focal overexpression of CEACAM6 contributes to enhanced tumourigenesis in head and neck cancer via suppression of apoptosis Academic Article
Focus on extracellular vesicles: introducing the next small big thing Academic Article
Fold up or perish: unfolded protein response and chemotherapy Academic Article
Formaldehyde-releasing prodrugs specifically affect cancer cells by depletion of intracellular glutathione and augmentation of reactive oxygen species Academic Article
Fra-1 replaces c-Fos-dependent functions in mice Academic Article
Functional and biochemical characterization of the baculovirus caspase inhibitor MaviP35 Academic Article
Functional regulation of the plasma protein histidine-rich glycoprotein by ZN2+ in settings of tissue injury Academic Article
Further Insights into the Effects of Pre-organizing the BimBH3 Helix [Addendum ] Erratum
Gata4 is required for maintenance of postnatal cardiac function and protection from pressure overload-induced heart failure Academic Article
Gene expression profiling of intestinal epithelial cell maturation along the crypt-villus axis Academic Article
Gold and Silver Nanoparticles Biomimetically Synthesized Using Date Palm Pollen Extract-Induce Apoptosis and Regulate p53 and Bcl-2 Expression in Human Breast Adenocarcinoma Cells Academic Article
Gp130-dependent astrocytic survival is critical for the control of autoimmune central nervous system inflammation Academic Article
Group A Streptococcus Modulates Host Inflammation by Manipulating Polymorphonuclear Leukocyte Cell Death Responses Academic Article
Growth suppression of intracranial xenografted glioblastomas overexpressing mutant epidermal growth factor receptors by systemic administration of monoclonal antibody (mAb) 806, a novel monoclonal antibody directed to the receptor Academic Article
Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes Academic Article
HDAC4 Promotes Growth of Colon Cancer Cells via Repression of p21 Academic Article
HDACs and HDAC inhibitors in colon cancer Academic Article
HOIP deficiency causes embryonic lethality by aberrant TNFR1-mediated endothelial cell death Academic Article
HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death Academic Article
Haploinsufficiency of the corepressor of estrogen receptor activity (REA) enhances estrogen receptor function in the mammary gland Academic Article
Heat Shock Protein 72 Modulates Pathways of Stress-induced Apoptosis Academic Article
Hepatitis C virus-induced hepatocyte cell death and protection by inhibition of apoptosis Academic Article
Hepatitis C-induced hepatocyte apoptosis following liver transplantation is enhanced by immunosuppressive agents Academic Article
Hepatocyte growth factor renders BRAF mutant human melanoma cell lines resistant to PLX4032 by downregulating the pro-apoptotic BH3-only proteins PUMA and BIM Academic Article
Heritable pathologic cardiac hypertrophy in adulthood is preceded by neonatal cardiac growth restriction Academic Article
High strain mechanical loading rapidly induces tendon apoptosis: an ex vivo rat tibialis anterior model Academic Article
Histidine-rich Glycoprotein Specifically Binds to Necrotic Cells via Its Amino-terminal Domain and Facilitates Necrotic Cell Phagocytosis Academic Article
Histone Deacetylase 3 (HDAC3) and Other Class I HDACs Regulate Colon Cell Maturation and p21 Expression and Are Deregulated in Human Colon Cancer Academic Article
Homogeneity of active demyelinating lesions in established multiple sclerosis Academic Article
Hoxb8 regulates expression of microRNAs to control cell death and differentiation Academic Article
Hsp70 Architecture: The Formation of Novel Polymeric Structures of Hsp70.1 and Hsc70 after Proteotoxic Stress Academic Article
Hsp72 Inhibits Apoptosis Upstream of the Mitochondria and Not through Interactions with Apaf-1 Academic Article
Hsp72 Inhibits Fas-mediated Apoptosis Upstream of the Mitochondria in Type II Cells Academic Article
Hsp72 chaperone function is dispensable for protection against stress-induced apoptosis Academic Article
HtrA2 Promotes Cell Death through Its Serine Protease Activity and Its Ability to Antagonize Inhibitor of Apoptosis Proteins Academic Article
HtrA2/Omi, a Sheep in Wolf's Clothing Academic Article
Human Bcl-2 cannot directly inhibit the Caenorhabditis elegans Apaf-1 homologue CED-4, but can interact with EGL-1 Academic Article
Human beta-defensin 3 contains an oncolytic motif that binds PI(4,5)P-2 to mediate tumour cell permeabilisation Academic Article
Human telomerase reverse transcriptase protects hematopoietic progenitor TF-1 cells from death and quiescence induced by cytokine withdrawal Academic Article
Human, insect and nematode caspases kill Saccharomyces cerevisiae independently of YCA1 and Aif1p Academic Article
Hurpin Is a Selective Inhibitor of Lysosomal Cathepsin L and Protects Keratinocytes from Ultraviolet-Induced Apoptosis † Academic Article
Hypoxia Enhances the Proliferative Response of Macrophages to CSF-1 and Their Pro-Survival Response to TNF Academic Article
IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis Academic Article
IAP family of cell death and signaling regulators Chapter
IAPS and ubiquitylation Academic Article
IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-κB as well as cell survival and oncogenesis Academic Article
IGF-I activates PKB and prevents anoxic apoptosis in Achilles tendon cells Academic Article
IGFBP-3 regulates esophageal tumor growth through IGF-dependent and independent mechanisms Academic Article
IL-6 Regulates Neutrophil Trafficking during Acute Inflammation via STAT3 Academic Article
IMP-1 displays cross-talk with K-Ras and modulates colon cancer cell survival through the novel proapoptotic protein CYFIP2 Academic Article
Identification of DIABLO, a Mammalian Protein that Promotes Apoptosis by Binding to and Antagonizing IAP Proteins Academic Article
Identification of an activation site in Bak and mitochondrial Bax triggered by antibodies Academic Article
Immunopathology of apoptosis ?introduction and overview Academic Article
Impact of conditional deletion of the pro-apoptotic BCL-2 family member BIM in mice Academic Article
In Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1-Rok-Myosin-II and JNK signalling Academic Article
In mouse embryonic fibroblasts, neither caspase-8 nor cellular FLICE-inhibitory protein (FLIP) is necessary for TNF to activate NF-κB, but caspase-8 is required for TNF to cause cell death and induction of FLIP by NF-κB is required to prevent it Academic Article
In vitro and in vivo evaluation of the influence of type III NaPi co-transporter activity during apoptosis on 99mTc-(V)DMSA uptake in the human leukaemic cell line U937 Academic Article
Induction of apoptosis by plant natriuretic peptides in rat cardiomyoblasts Academic Article
Inflammasome adaptor ASC suppresses apoptosis of gastric cancer cells by an IL18-mediated inflammation-independent mechanism Academic Article
Inflammation and depression: Why poststroke depression may be the norm and not the exception Academic Article
Inhibition of Bak Activation by VDAC2 Is Dependent on the Bak Transmembrane Anchor Academic Article
Inhibition of Bcl-2 or IAP proteins does not provoke mutations in surviving cells Academic Article
Inhibition of apoptosis and clonogenic survival of cells expressing crmA variants: optimal caspase substrates are not necessarily optimal inhibitors Academic Article
Inhibition of cathepsin proteases attenuates migration and sensitizes aggressive N-Myc amplified human neuroblastoma cells to doxorubicin Academic Article
Inhibition of interleukin 1 -converting enzyme-mediated apoptosis of mammalian cells by baculovirus IAP Conference Paper
Inhibition of osteoblast apoptosis by thrombin Academic Article
Inhibitor of Apoptosis (IAP) Proteins-Modulators of Cell Death and Inflammation Academic Article
Inhibitor of Apoptosis Proteins Limit RIP3 Kinase-Dependent Interleukin-1 Activation Academic Article
Inhibitor of apoptosis protein (IAP) antagonists demonstrate divergent immunomodulatory properties in human immune subsets with implications for combination therapy Academic Article
Inhibitor of apoptosis protein-1 regulates tumor necrosis factor-mediated destruction of intestinal epithelial cells Academic Article
Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs Academic Article
Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells Academic Article
Insights from bcl-2 and myc: Malignancy involves abrogation of apoptosis as well as sustained proliferation Conference Paper
Integral membrane protease fibroblast activation protein sensitizes fibrosarcoma to chemotherapy and alters cell death mechanisms Academic Article
Interleukin 15–mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1 Academic Article
Interleukin-11 links oxidative stress and compensatory proliferation Academic Article
Interleukin-6 promotes pulmonary emphysema associated with apoptosis in mice Academic Article
Interpreting CFSE Obtained Division Histories of B Cells in Vitro with Smith–Martin and Cyton Type Models Academic Article
Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis Academic Article
Isolation of cardiomyocytes and cardiofibroblasts for ex vivo analysis Chapter
Isolation of cell type-specific apoptotic bodies by fluorescence-activated cell sorting Academic Article
Jekyll and Hyde: The other life of the death ligand TRAIL Comment
Jekyll and Hyde; changing places, changing faces Academic Article
Kainate-induced apoptosis correlates with c-Jun activation in cultured cerebellar granule cells Academic Article
Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins Academic Article
LIM kinase inhibition reduces breast cancer growth and invasiveness but systemic inhibition does not reduce metastasis in mice Academic Article
Leukocytes Induce Epithelial to Mesenchymal Transition after Unilateral Ureteral Obstruction in Neonatal Mice Academic Article
Lgl, the SWH pathway and tumorigenesis: It’s a matter of context and competition! Academic Article
Life, death, and antibodies Comment
Lipopolysaccharide-induced myocardial protection against ischaemia/reperfusion injury is mediated through a PI3K/Akt-dependent mechanism Academic Article
Localization of dynein light chains 1 and 2 and their pro-apoptotic ligands Academic Article
Loss of Host Type-I IFN Signaling Accelerates Metastasis and Impairs NK-cell Antitumor Function in Multiple Models of Breast Cancer Academic Article
Loss of Prkar1a leads to Bcl-2 family protein induction and cachexia in mice Academic Article
Loss of steroid receptor co-activator-3 attenuates carbon tetrachloride-induced murine hepatic injury and fibrosis Academic Article
Loss of the Pro-Apoptotic BH3-only Bcl-2 Family Member Bim Inhibits BCR Stimulation–induced Apoptosis and Deletion of Autoreactive B Cells Academic Article
Lymphotoxin α induces apoptosis, necroptosis and inflammatory signals with the same potency as tumour necrosis factor Academic Article
M2, a novel anthracenedione, elicits a potent DNA damage response that can be subverted through checkpoint kinase inhibition to generate mitotic catastrophe Academic Article
MCMV-mediated Inhibition of the Pro-apoptotic Bak Protein Is Required for Optimal In Vivo Replication Academic Article
MK2 phosphorylates RIPK1 to prevent TNF-induced cell death Academic Article
MYB80 homologues in Arabidopsis, cotton and Brassica: regulation and functional conservation in tapetal and pollen development Academic Article
Making Sense of HDAC2 Mutations in Colon Cancer Academic Article
Mammalian initiator apoptotic caspases Academic Article
Mammalian mitochondrial IAP binding proteins Academic Article
Mechanisms of resistance to high and low linear energy transfer radiation in myeloid leukemia cells Academic Article
Membrane-bound Fas ligand only is essential for Fas-induced apoptosis Academic Article
Menadione (Vitamin K3) Induces Apoptosis of Human Oral Cancer Cells and Reduces their Metastatic Potential by Modulating the Expression of Epithelial to Mesenchymal Transition Markers and Inhibiting Migration Academic Article
Midbrain-hindbrain boundary patterning and morphogenesis are regulated by diverse grainy head-like 2-dependent pathways Academic Article
Mitochondria-Targeted Chemotherapeutics: The Rational Design of Gold(I) N -Heterocyclic Carbene Complexes That Are Selectively Toxic to Cancer Cells and Target Protein Selenols in Preference to Thiols Academic Article
Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming Academic Article
Mitochondrial morphology and distribution in mammalian cells Academic Article
Mitoxantrone Mediates Demethylation and Re-Expression of Cyclin D2, Estrogen Receptor 14.3.3 Sigma In Breast Cancer Cells Academic Article
Modeling Biological Activities of Nanoparticles Academic Article
Modeling T- and B-cell growth and differentiation Academic Article
Modeling metazoan apoptotic pathways in yeast Chapter
Modifications and intracellular trafficking of FADD/MORT1 and caspase-8 after stimulation of T lymphocytes Academic Article
Modified vaccinia virus Ankara protein F1L is a novel BH3-domain-binding protein and acts together with the early viral protein E3L to block virus-associated apoptosis Academic Article
Modulation of Cellular Hsp72 Levels in Undifferentiated and Neuron-Like SH-SY5Y Cells Determines Resistance to Staurosporine-Induced Apoptosis Academic Article
Modulation of the Multidrug Resistance of Glioma by Glutathione Levels Depletion - Interaction with TC-99M-Sestamibi and TC-99M-Tetrofosmin Academic Article
Molecular and clinical aspects of apoptosis Academic Article
Molecular mechanisms of action and prediction of response to oxaliplatin in colorectal cancer cells Academic Article
Molecular mechanisms of apoptosis: an overview. Academic Article
Molecular mechanisms of late apoptotic/necrotic cell clearance Academic Article
Monitoring activity of caspases and their regulators in yeast Saccharomyces cerevisiae Book
Motor neurone disease and the life of motor neurones Academic Article
Multifaceted deaths orchestrated by mitochondria in neurones Academic Article
Multifaceted effects of ATP on cardiolipin-bound cytochrome c Academic Article
Multiple Autocrine Factors Including an Extracellular Matrix Protein are Required for the Proliferation and Spreading of Human Colon Carcinoma Cells In Vitro Academic Article
Mutation to bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosis Academic Article
NADPH oxidase isoform selective regulation of endothelial cell proliferation and survival Academic Article
NF-κB Inhibition Reveals Differential Mechanisms of TNF Versus TRAIL-Induced Apoptosis Upstream or at the Level of Caspase-8 Activation Independent of cIAP2 Academic Article
Necroptosis induced by RIPK3 requires MLKL but not Drp1 Academic Article
Nedd4-WW Domain-Binding Protein 5 (Ndfip1) Is Associated with Neuronal Survival after Acute Cortical Brain Injury Academic Article
Neither macromolecular synthesis nor myc is required for cell death via the mechanism that can be controlled by Bcl-2. Academic Article
NetPath: a public resource of curated signal transduction pathways Academic Article
Nobel prize for physiology or medicine 2002 is awarded for research into the genetic regulation of organ development and programmed cell death Academic Article
Oncolytic reovirus preferentially induces apoptosis in KRAS mutant colorectal cancer cells, and synergizes with irinotecan Academic Article
Over-Expression of DSCR1 Protects against Post-Ischemic Neuronal Injury Academic Article
Overexpression of Endogenous Anti-Oxidants with Selenium Supplementation Protects Trophoblast Cells from Reactive Oxygen Species-Induced Apoptosis in a Bcl-2-Dependent Manner Academic Article
Overexpression of insulin-like growth factor binding protein-6 inhibits rhabdomyosarcoma growthin vivo Academic Article
P2X7 receptor activation induces cell death and CD23 shedding in human RPMI 8226 multiple myeloma cells Academic Article
PD-L1 and IAPs co-operate to protect tumors from cytotoxic lymphocyte-derived TNF Academic Article
PSGL-1-Mediated Adhesion of Human Hematopoietic Progenitors to P-Selectin Results in Suppression of Hematopoiesis Academic Article
Partially redundant functions of SRC-1 and TIF2 in postnatal survival and male reproduction Academic Article
Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack Academic Article
Peri-partum Changes in the Intraepithelial Lymphocyte Population of Sheep Interplacentomal Endometrium Academic Article
Physiological restraint of Bak by Bcl-x(L) is essential for cell survival Academic Article
Pin1 promotes neuronal death in stroke by stabilizing notch intracellular domain Academic Article
Platelet senescence is regulated by an internal timer, not damage inflicted by hits Academic Article
Plumbagin Downregulates Wnt Signaling Independent of p53 in Human Colorectal Cancer Cells Academic Article
Porphyromonas gingivalis RgpA-Kgp Proteinase-Adhesin Complexes Penetrate Gingival Tissue and Induce Proinflammatory Cytokines or Apoptosis in a Concentration-Dependent Manner Academic Article
Postchemotherapy and Tumor-Selective Targeting with the La-Specific DAB4 Monoclonal Antibody Relates to Apoptotic Cell Clearance Academic Article
Prevention Of Cyclophosphamide-Induced And Spontaneous Diabetes In Nod Mice By Syngeneic Splenocytes Treated With Cytotoxic Drugs Academic Article
Pro-apoptotic Bim suppresses breast tumor cell metastasis and is a target gene of SNAI2 Academic Article
Proapoptotic Bcl-2 family member Bim is involved in the control of mast cell survival and is induced together with Bcl-XL upon IgE-receptor activation Academic Article
Programmed Cell Death and Senescence in Skeletal Muscle Stem Cells Conference Paper
Programmed cell death: Superman meets Dr Death Conference Paper
Progranulin does not inhibit TNF and lymphotoxin-signalling through TNF receptor 1 Academic Article
Proliferation centers in chronic lymphocytic leukemia: the niche where NF-κB activation takes place Academic Article
Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak Academic Article
Prosurvival Bcl-2 family members reveal a distinct apoptotic identity between conventional and plasmacytoid dendritic cells Academic Article
Protease-activated receptor-2 mediates proliferative responses in skeletal myoblasts Academic Article
Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Academic Article
Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim Academic Article
Quinazoline Sulfonamides as Dual Binders of the Proteins B-Cell Lymphoma 2 and B-Cell Lymphoma Extra Long with Potent Proapoptotic Cell-Based Activity Academic Article
RIP-in CD95-induced cell death: The control of alternative death receptors pathways by cIAPs Academic Article
RIPK1-and RIPK3-induced cell death mode is determined by target availability Academic Article
RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL Academic Article
Radioimmunotherapy with -Particle-Emitting 213Bi-C-Functionalized trans-Cyclohexyl-Diethylenetriaminepentaacetic Acid-Humanized 3S193 Is Enhanced by Combination with Paclitaxel Chemotherapy Conference Paper
Radiosensitizing activity of a novel Benzoxazine through the promotion of apoptosis and inhibition of DNA repair Academic Article
Recent Advances in Understanding and Exploiting the Activation of Anthracyclines by Formaldehyde Academic Article
Recruitment of mitochondria into apoptotic signaling correlates with the presence of inclusions formed by amyotrophic lateral sclerosis-associated SOD1 mutations Academic Article
Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction Academic Article
Regulation of Enterocyte Apoptosis by Acyl-CoA Synthetase 5 Splicing Academic Article
Regulation of Insulin Secretion and -Cell Mass by Activating Signal Cointegrator 2 Academic Article
Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs Academic Article
Repurposing apoptosis-inducing cancer drugs to treat schistosomiasis Academic Article
Requirements for proteolysis during apoptosis. Academic Article
Residue-Based Preorganization of BH3-Derived α/β-Peptides: Modulating Affinity, Selectivity and Proteolytic Susceptibility in α-Helix Mimics Academic Article
Resistance to butyrate-induced cell differentiation and apoptosis during spontaneous Caco-2 cell differentiation Academic Article
Resistin, an adipocytokine, offers protection against acute myocardial infarction Academic Article
Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP Academic Article
Role of a novel benzoxazine derivative in the chemosensitization of colon cancer Academic Article
Role of p53 in cAMP/PKA pathway mediated apoptosis Academic Article
STAT3: A central mediator of pulmonary fibrosis? Academic Article
STRICA, a novel Drosophila melanogaster caspase with an unusual serine/threonine-rich prodomain, interacts with DIAP1 and DIAP2 Academic Article
Scribble acts as an oncogene in Em-myc-driven lymphoma Academic Article
Selective inhibition of endogenous antioxidants with Auranofin causes mitochondrial oxidative stress which can be countered by selenium supplementation Academic Article
Sequence as well as functional similarity for DIABLO/Smac and Grim, Reaper and Hid? Academic Article
Sex-Dependent Effects of G Protein-Coupled Estrogen Receptor Activity on Outcome After Ischemic Stroke Academic Article
SfDronc, an initiator caspase involved in apoptosis in the fall armyworm Spodoptera frugiperda Academic Article
Sheeppox Virus SPPV14 Encodes a Bcl-2-Like Cell Death Inhibitor That Counters a Distinct Set of Mammalian Proapoptotic Proteins Academic Article
Signal transducer and activator of transcription 2 deficiency is a novel disorder of mitochondrial fission Academic Article
Signalling by CD95 and TNF receptors: Not only life and death Academic Article
Smac Mimetics Activate the E3 Ligase Activity of cIAP1 Protein by Promoting RING Domain Dimerization Academic Article
Solution structure of a baculoviral inhibitor of apoptosis (IAP) repeat Academic Article
Spectrum of Radiopharmaceuticals in Nuclear Oncology Academic Article
Stabilizing the Pro-Apoptotic BimBH3 Helix (BimSAHB) Does Not Necessarily Enhance Affinity or Biological Activity Academic Article
Steroid Receptor Coactivator-3 Is Required for Inhibition of Neointima Formation by Estrogen Academic Article
Stress proteins and apoptosis in prenatal development, cancer and medicine Academic Article
Structural Basis for Apoptosis Inhibition by Epstein-Barr Virus BHRF1 Academic Article
Structural and functional insight into canarypox virus CNP058 mediated regulation of apoptosis Academic Article
Structural basis of Deerpox virus-mediated inhibition of apoptosis Academic Article
Structural biology of the Bcl-2 family and its mimicry by viral proteins Academic Article
Structural insight into African swine fever virus A179L-mediated inhibition of apoptosis Academic Article
Structural insight into an evolutionarily ancient programmed cell death regulator – the crystal structure of marine sponge BHP2 bound to LB-Bak-2 Academic Article
Structural insights into the degradation of Mcl-1 induced by BH3 domains Academic Article
Structure-guided design of a selective BCL-XL inhibitor Academic Article
Sublethal Concentrations of Prion Peptide PrP106–126 or the Amyloid Beta Peptide of Alzheimer's Disease Activates Expression of Proapoptotic Markers in Primary Cortical Neurons Academic Article
Subversion of the Bcl-2 Life/Death Switch in Cancer Development and Therapy Conference Paper
Sulindac modulates secreted protein expression from LIM1215 colon carcinoma cells prior to apoptosis Academic Article
TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1 Academic Article
TR3/Nur77 in colon cancer cell apoptosis Academic Article
TRAF2 Must Bind to Cellular Inhibitors of Apoptosis for Tumor Necrosis Factor (TNF) to Efficiently Activate NF-κB and to Prevent TNF-induced Apoptosis Academic Article
TRAF2 regulates TNF and NF-kappa B signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1 Academic Article
TRAIL and Malignant Glioma Academic Article
TRAIL in cancer therapy: present and future challenges Academic Article
TRAIL-R4 Promotes Tumor Growth and Resistance to Apoptosis in Cervical Carcinoma HeLa Cells through AKT Academic Article
TRAIL-induced apoptosis is enhanced by heat shock protein 70 expression Academic Article
Targeting BCL-2 to enhance vulnerability to therapy in estrogen receptor-positive breast cancer Academic Article
Targeting EphA3 inhibits cancer growth by disrupting the tumor stromal microenvironment Academic Article
Targeting the upregulation of reactive oxygen species subsequent to hyperglycemia prevents type 1 diabetic cardiomyopathy in mice Academic Article
Tenocyte responses to mechanical loading in vivo - A role for local insulin-like growth factor 1 signaling in early tendinosis in rats Academic Article
Tenocyte responses to mechanical loading in vivo: A role for local insulin-like growth factor 1 signaling in early tendinosis in rats Academic Article
The BECN1 N-terminal domain is intrinsically disordered Academic Article
The Bcl-2 family in autoimmune and degenerative disorders Academic Article
The Bcl-2 family in host-virus interactions Academic Article
The Bcl-2 family: structures, interactions and targets for drug discovery Academic Article
The Caenorhabditis elegans CED-9 protein does not directly inhibit the caspase CED-3, in vitro nor in yeast Academic Article
The Carboxyl-Terminal Domain of Inducible Hsp70 Protects from Ischemic Injury in vivo and in vitro Academic Article
The Complete DNA Sequence of Myxoma Virus Academic Article
The Drosophila Caspase Inhibitor DIAP1 Is Essential for Cell Survival and Is Negatively Regulated by HID Academic Article
The Drosophila caspase DRONC cleaves following glutamate or aspartate and is regulated by DIAP1, HID, and GRIM Academic Article
The Drosophila caspase DRONC is regulated by DIAP1 Academic Article
The FLIP side of life Academic Article
The N Terminus of the Vaccinia Virus Protein F1L Is an Intrinsically Unstructured Region That Is Not Involved in Apoptosis Regulation Academic Article
The Proapoptotic Activity of the Bcl-2 Family Member Bim Is Regulated by Interaction with the Dynein Motor Complex Academic Article
The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis Academic Article
The Receptor Tyrosine Kinase EPHB4 Has Tumor Suppressor Activities in Intestinal Tumorigenesis Academic Article
The Role of Bim, a Proapoptotic BH3-Only Member of the Bcl-2 Family, in Cell-Death Control Conference Paper
The Role of Protease-Activated Receptor-1 in Bone Healing Academic Article
The Role of the Pro-Apoptotic Bcl-2 Family Member Bim in Physiological Cell Death Conference Paper
The Salvador/Warts/Hippo pathway controls regenerative tissue growth in Drosophila melanogaster Academic Article
The Structural Biology of BH3-Only Proteins Academic Article
The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3– and caspase 9–interacting sites Academic Article
The apoptosis pathway and the genetic predisposition to Achilles tendinopathy Academic Article
The cardio-protecting agent and topoisomerase II catalytic inhibitor sobuzoxane enhances doxorubicin-DNA adduct mediated cytotoxicity Academic Article
The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia Academic Article
The effect of gefitinib (Iressa, ZD1839) in combination with oxaliplatin is schedule-dependent in colon cancer cell lines Academic Article
The functional differences between pro-survival and pro-apoptotic B cell lymphoma 2 (Bcl-2) proteins depend on structural differences in their Bcl-2 homology 3 (BH3) domains Academic Article
The hydroxyl epimer of doxorubicin controls the rate of formation of cytotoxic anthracycline-DNA adducts Academic Article
The importance of being chaperoned: HSP90 and necroptosis Other Publication
The intersection of cell death and inflammasome activation Academic Article
The medical significance of physiological cell death Academic Article
The mitochondrial death squad: hardened killers or innocent bystanders? Academic Article
The molecular biology of apoptosis. Academic Article
The p35 relative, p49, inhibits mammalian and Drosophila caspases including DRONC and protects against apoptosis Academic Article
The polycomb repressive complex 2 governs life and death of peripheral T cells Academic Article
The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism Academic Article
The regulation of TNF signalling: What a tangled web we weave Academic Article
The regulation of mitochondrial morphology: Intricate mechanisms and dynamic machinery Academic Article
The restricted binding repertoire of Bcl-B leaves Bim as the universal BH3-only prosurvival Bcl-2 protein antagonist Academic Article
The role of BH3-only protein Bim extends beyond inhibiting Bcl-2–like prosurvival proteins Academic Article
The role of the Bcl-2 family of apoptosis regulatory proteins in the immune system Academic Article
The role of the E2F transcription factor family in UV-induced apoptosis Academic Article
The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy Academic Article
The schedule-dependent enhanced cytotoxic activity of 7-ethyl-10-hydroxy-camptothecin (SN-38) in combination with Gefitinib (Iressa™, ZD1839) Academic Article
The small molecule that packs a punch: ubiquitin-mediated regulation of RIPK1/FADD/caspase-8 complexes Academic Article
Therapeutic anti-EGFR antibody 806 generates responses in murine de novo EGFR mutant–dependent lung carcinomas Academic Article
Therapeutic efficacy of 177 Lu-CHX-A″-DTPA-hu3S193 radioimmunotherapy in prostate cancer is enhanced by EGFR inhibition or docetaxel chemotherapy Academic Article
Therapeutic inhibition of Jak activity inhibits progression of gastrointestinal tumors in mice Academic Article
Thirty years of BCL-2: translating cell death discoveries into novel cancer therapies Academic Article
Till Death Do Us Part Academic Article
Tissue sensitivity to thyroid hormone in athyroid Xenopus laevis larvae Academic Article
To Trigger Apoptosis, Bak Exposes Its BH3 Domain and Homodimerizes via BH3:Groove Interactions Academic Article
Toward an understanding of the molecular mechanisms of physiological cell death. Academic Article
Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance Academic Article
Transduction of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand into Hematopoietic Cells Leads to Inhibition of Syngeneic Tumor Growth In vivo Academic Article
Trefoil Factor 3 Is Oncogenic and Mediates Anti-Estrogen Resistance in Human Mammary Carcinoma Academic Article
Triggering of Apoptosis by Puma Is Determined by the Threshold Set by Prosurvival Bcl-2 Family Proteins Academic Article
Tumor Cell Response to Synchrotron Microbeam Radiation Therapy Differs Markedly From Cells in Normal Tissues Academic Article
Tumor Necrosis Factor (TNF) Signaling, but Not TWEAK (TNF-like Weak Inducer of Apoptosis)-triggered cIAP1 (Cellular Inhibitor of Apoptosis Protein 1) Degradation, Requires cIAP1 RING Dimerization and E2 Binding Academic Article
Tumor-specific nuclear targeting: Promises for anti-cancer therapy? Academic Article
Tumorigenic Poxviruses Up-Regulate Intracellular Superoxide To Inhibit Apoptosis and Promote Cell Proliferation Academic Article
Two kinds of BIR-containing protein - Inhibitors of apoptosis, or required for mitosis Academic Article
Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2 Academic Article
Unexpected link between an antibiotic, pannexin channels and apoptosis Academic Article
Unlike Diablo/smac, Grim Promotes Global Ubiquitination and Specific Degradation of X Chromosome-linked Inhibitor of Apoptosis (XIAP) and Neither Cause Apoptosis Academic Article
Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands Academic Article
Vaccinia virus encodes a novel inhibitor of apoptosis that associates with the apoptosome Academic Article
Variola virus F1L is a Bcl-2-like protein that unlike its vaccinia virus counterpart inhibits apoptosis independent of Bim Academic Article
Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation Academic Article
Viewing BCL2 and cell death control from an evolutionary perspective Academic Article
Viral Infection and Apoptosis Editorial Article
Viral Inhibitors of Apoptosis Academic Article
Viral, worm and radical implications for apoptosis Academic Article
What do we know about the mechanisms of elimination of autoreactive T and B cells and what challenges remain Academic Article
What you eat is what you are - A role for polyunsaturated fatty acids in neuroinflammation induced depression? Academic Article
XIAP discriminates between type I and type II FAS-induced apoptosis Academic Article
XIAP-deficiency leads to delayed lobuloalveolar development in the mammary gland Academic Article
Yeast techniques for modeling drugs targeting Bcl-2 and caspase family members Academic Article
[6]-gingerol as a cancer chemopreventive agent: A review of its activity on different steps of the metastatic process Academic Article
c-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis Academic Article
cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1-and RIPK3-dependent manner Academic Article
gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis Academic Article
scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila Academic Article
scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs Academic Article
β-Catenin/Tcf-4 Inhibition After Progastrin Targeting Reduces Growth and Drives Differentiation of Intestinal Tumors Academic Article

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