Apoptosis
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(α/β+α)-Peptide Antagonists of BH3 Domain/Bcl-xLRecognition: Toward General Strategies for Foldamer-Based Inhibition of Protein−Protein Interactions Academic Article
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2-Methoxyestradiol – a unique blend of activities generating a new class of anti-tumour/anti-inflammatory agents Academic Article
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8 Apoptosis, haemopoiesis and leukaemogenesis Academic Article
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A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs Academic Article
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A Functional Yeast Survival Screen of Tumor-Derived cDNA Libraries Designed to Identify Anti-Apoptotic Mammalian Oncogenes Academic Article
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A QCM-D and SAXS Study of the Interaction of Functionalised Lyotropic Liquid Crystalline Lipid Nanoparticles with siRNA Academic Article
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A Structural Investigation of NRZ Mediated Apoptosis Regulation in Zebrafish Academic Article
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A Structural Viral Mimic of Prosurvival Bcl-2: A Pivotal Role for Sequestering Proapoptotic Bax and Bak Academic Article
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A T cell-specific knockout reveals an important role for protease-activated receptor 2 in lymphocyte development Academic Article
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A comparison of novel organoiridium(III) complexes and their ligands as a potential treatment for prostate cancer Academic Article
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A conformational change of C-reactive protein in burn wounds unmasks its proinflammatory properties Academic Article
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A dual functional AEE fluorogen as a mitochondrial-specific bioprobe and an effective photosensitizer for photodynamic therapy Academic Article
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A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma Academic Article
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A novel Apaf-1–independent putative caspase-2 activation complex Academic Article
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A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation Academic Article
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A novel influenza A virus mitochondrial protein that induces cell death Academic Article
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A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure Academic Article
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A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis Academic Article
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ABT-737, proving to be a great tool even before it is proven in the clinic Academic Article
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AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC Academic Article
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APOPTOSIS: A Cinderella Caspase Takes Center Stage Academic Article
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ATF3 Repression of BCL-X L Determines Apoptotic Sensitivity to HDAC Inhibitors across Tumor Types Academic Article
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Absence of autophagy promotes apoptosis by modulating the ROS-dependent RLR signaling pathway in classical swine fever virus-infected cells Academic Article
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Absence of caveolin-1 alters heat shock protein expression in spontaneous mammary tumors driven by Her-2/neu expression Academic Article
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Activation of clinically used anthracyclines by the formaldehyde-releasing prodrug pivaloyloxymethyl butyrate Academic Article
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Activation of physiological cell death mechanisms by a necrosis-causing agent Academic Article
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Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death Academic Article
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Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner Academic Article
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Alterations in the apoptotic machinery and their potential role in anticancer drug resistance Academic Article
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Alternative oxidase: a target and regulator of stress responses Academic Article
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Alternative splicing of Bim and Erk-mediated Bim EL phosphorylation are dispensable for hematopoietic homeostasis in vivo Academic Article
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An Essential Role for the Caspase Dronc in Developmentally Programmed Cell Death inDrosophila Academic Article
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An appointment with death,: 2013 Cold Spring Harbor Asia meeting 'Mechanisms and Functions of Non-Apoptotic Cell Death' Conference Paper
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An evolutionary perspective on apoptosis Academic Article
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An optimized method for establishing high purity murine CD8+ T cell cultures Academic Article
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Analysis of FasL and TRAIL induced apoptosis pathways in glioma cells Academic Article
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Analysis of candidate antagonists of IAP-mediated caspase inhibition using yeast reconstituted with the mammalian Apaf-1-activated apoptosis mechanism Academic Article
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Analysis of the Role of bcl-2 in Apoptosis Academic Article
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Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma Academic Article
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Angiotensin II Type 2 Receptor Stimulation Initiated After Stroke Causes Neuroprotection in Conscious Rats Academic Article
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Another twist in the on and off affair between cell suicide and inflammation Editorial Article
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Antagonism of IAPs enhances CAR T-cell efficacy Academic Article
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Anti-apoptotic potential of insect cellular and viral IAPs in mammalian cells Academic Article
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Anti‐TIM‐1 Monoclonal Antibody (RMT1‐10) Attenuates Atherosclerosis By Expanding IgM‐producing B1a Cells Academic Article
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Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die Academic Article
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Apoptogenic factors released from mitochondria Academic Article
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Apoptosis Initiated When BH3 Ligands Engage Multiple Bcl-2 Homologs, Not Bax or Bak Academic Article
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Apoptosis Timeline Academic Article
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Apoptosis and the immune system Academic Article
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Apoptosis and toxicology—what relevance? Academic Article
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Apoptosis genes and autoimmunity Academic Article
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Apoptosis in schistosomes: toward novel targets for the treatment of schistosomiasis Academic Article
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Apoptosis in the development and treatment of cancer Academic Article
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Apoptosis induced in synchronized human immunodeficiency virus type 1-infected primary peripheral blood mononuclear cells is detected after the peak of CD4+ T-lymphocyte loss and is dependent on the tropism of the gp120 envelope glycoprotein Academic Article
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Apoptosis inhibitor 5 is an endogenous inhibitor of caspase‐2 Academic Article
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Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome Academic Article
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Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax Academic Article
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Apoptosis: A sticky business Academic Article
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Apoptotic Mechanisms After Cerebral Ischemia Academic Article
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Apoptotic Sensitivity of Colon Cancer Cells to Histone Deacetylase Inhibitors Is Mediated by an Sp1/Sp3-Activated Transcriptional Program Involving Immediate-Early Gene Induction Academic Article
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Apoptotic cell clearance: basic biology and therapeutic potential Academic Article
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Apoptotic cells secrete metabolites to regulate immune homeostasis Academic Article
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Apoptotic pore formation is associated with in-plane insertion of Bak or Bax central helices into the mitochondrial outer membrane Academic Article
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Apoptotic, necrotic, or fused tumor cells: An equivalent source of antigen for dendritic cell loading Academic Article
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Ars Moriendi; the art of dying well - new insights into the molecular pathways of necroptotic cell death. Academic Article
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Arsenic Trioxide Induces Apoptosis of Human Monocytes during Macrophagic Differentiation through Nuclear Factor-κB-Related Survival Pathway Down-Regulation Academic Article
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Aspirin inhibits camptothecin-induced p21CIP1 levels and potentiates apoptosis in human breast cancer cells Academic Article
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Ataxin-2 interacts with FUS and intermediate-length polyglutamine expansions enhance FUS-related pathology in amyotrophic lateral sclerosis Academic Article
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Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists, 1994: HYPOTHESIS: APOPTOSIS CAUSED BY CYTOTOXINS REPRESENTS A DEFENSIVE RESPONSE THAT EVOLVED TO COMBAT INTRACELLULAR PATHOGENS Conference Paper
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Autophagy induced during apoptosis degrades mitochondria and inhibits type I interferon secretion Academic Article
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BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis Academic Article
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BAX-BAK1-independent LC3B lipidation by BH3 mimetics is unrelated to BH3 mimetic activity and has only minimal effects on autophagic flux Academic Article
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BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals Academic Article
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BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival Academic Article
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BCL2 and related prosurvival proteins require BAK1 and BAX to affect autophagy Academic Article
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BH3-Mimetic Drugs: Blazing the Trail for New Cancer Medicines Academic Article
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BH3-Only proteins in health and disease Chapter
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BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes Academic Article
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BH3-only proteins: a 20-year stock-take Academic Article
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BMPs regulate differentiation of a putative visceral endoderm layer within human embryonic stem-cell-derived embryoid bodies Academic Article
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Bak apoptotic pores involve a flexible C-terminal region and juxtaposition of the C-terminal transmembrane domains Academic Article
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Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis Academic Article
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Bax targets mitochondria by distinct mechanisms before or during apoptotic cell death: a requirement for VDAC2 or Bak for efficient Bax apoptotic function Academic Article
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Bcl-2 Prevents Apoptosis Induced by Perforin and Granzyme B, but Not That Mediated by Whole Cytotoxic Lymphocytes Academic Article
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Bcl-2 and thermotolerance cooperate in cell survival Academic Article
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Bcl-2 delays and alters hepatic carcinogenesis induced by transforming growth factor Academic Article
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Bcl-2 family proteins: The sentinels of the mitochondrial apoptosis pathway Academic Article
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Bcl-2 in Cell Cycle Regulation Academic Article
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Bcl-2–regulated apoptosis and cytochrome c release can occur independently of both caspase-2 and caspase-9 Academic Article
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Bcl-x(L) inhibition enhances Dinaciclib-induced cell death in soft-tissue sarcomas Academic Article
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Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax Academic Article
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Bim Links ER Stress and Apoptosis in Cells Expressing Mutant SOD1 Associated with Amyotrophic Lateral Sclerosis Academic Article
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Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic Academic Article
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Bioenergetic differences selectively sensitize tumorigenic liver progenitor cells to a new gold(I) compound Academic Article
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Blocking granule-mediated death by primary human NK cells requires both protection of mitochondria and inhibition of caspase activity Academic Article
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Bone Morphogenetic Protein-7 Inhibits Telomerase Activity, Telomere Maintenance, and Cervical Tumor Growth Academic Article
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Both leukaemic and normal peripheral B lymphoid cells are highly sensitive to the selective pharmacological inhibition of prosurvival Bcl-2 with ABT-199 Academic Article
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Buffy, a Drosophila Bcl-2 protein, has anti-apoptotic and cell cycle inhibitory functions Academic Article
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Butyrate-induced apoptotic cascade in colonic carcinoma cells: Modulation of the β-catenin-Tcf pathway and concordance with effects of sulindac and trichostatin A but not curcumin Academic Article
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C-reactive protein: How conformational changes influence inflammatory properties Academic Article
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CD4 + T-cell deficiency in HIV patients responding to antiretroviral therapy is associated with increased expression of interferon-stimulated genes in CD4 + T cells Academic Article
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CED-4—The Third Horseman of Apoptosis Academic Article
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CREB-binding protein (CBP) regulates β-adrenoceptor (β-AR)−mediated apoptosis Academic Article
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Calsenilin contributes to neuronal cell death in ischemic stroke Academic Article
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Cancer and programmed cell death Conference Paper
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Cardioprotection Induced by Adenosine A1 Receptor Agonists in a Cardiac Cell Ischemia Model Involves Cooperative Activation of Adenosine A2A and A2B Receptors by Endogenous Adenosine Academic Article
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Cardioprotection from ischaemia–reperfusion injury by a novel flavonol that reduces activation of p38 MAPK Academic Article
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Caspase-14: a new player in cytotrophoblast differentiation Academic Article
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Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9 Academic Article
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Caspase-2 is resistant to inhibition by inhibitor of apoptosis proteins (IAPs) and can activate caspase-7 Academic Article
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Caspase-2: controversial killer or checkpoint controller? Academic Article
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Caspase-8 Cleaves Histone Deacetylase 7 and Abolishes Its Transcription Repressor Function Academic Article
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Caspase-8 levels affect necessity for mitochondrial amplification in death ligand-induced glioma cell apoptosis Academic Article
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Caspases and apoptosis – biology and terminology Academic Article
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Cell Death in Development Academic Article
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Cell death in chronic inflammation: breaking the cycle to treat rheumatic disease Academic Article
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Cell death in the origin and treatment of cancer Academic Article
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Cell death regulation by the mammalian IAP antagonist Diablo/Smac Academic Article
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Cell death: Shadow Baxing Academic Article
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Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment Academic Article
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Cellular Mechanisms of Risk and Transformation Conference Paper
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Characterisation of the novel apoptotic and therapeutic activities of the histone deacetylase inhibitor romidepsin Academic Article
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Characterization of ABBV-221, a Tumor-Selective EGFR-Targeting Antibody Drug Conjugate Academic Article
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Characterization of the ectromelia virus serpin, SPI-2
The GenBank accession number for ectromelia virus SPI-2 is AF219903. Academic Article
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Characterization of theDrosophilaCaspase, DAMM Academic Article
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Chemical chaperone TUDCA prevents apoptosis and improves survival during polymicrobial sepsis in mice Academic Article
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Chemo-sensitisation of HeLa cells to Etoposide by a Benzoxazine in the absence of DNA-PK inhibition Academic Article
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Chemotherapy overcomes TRAIL-R4-mediated TRAIL resistance at the DISC level Academic Article
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Circulating HtrA2 after primary percutaneous coronary intervention in ST-segment elevation myocardial infarction: A potential novel biomarker for mitochondrial induced cardiomyocyte apoptosis and ischemia-reperfusion injury Letter
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Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors. Academic Article
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Cloning of Mouse RP-8 cDNA and Its Expression During Apoptosis of Lymphoid and Myeloid Cells Academic Article
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Coenzyme Q10 attenuates diastolic dysfunction, cardiomyocyte hypertrophy and cardiac fibrosis in the db/db mouse model of type 2 diabetes Academic Article
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Colonic Cell Proliferation, Differentiation, and Apoptosis Conference Paper
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Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways Academic Article
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Combined gene expression and proteomic analysis of EGF induced apoptosis in A431 cells suggests multiple pathways trigger apoptosis Academic Article
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Computational Systems Biology Approach Predicts Regulators and Targets of microRNAs and Their Genomic Hotspots in Apoptosis Process Academic Article
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Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer Academic Article
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Cone photoreceptor neuroprotection conferred by CNTF in a novel in vivo model of battlefield retinal laser injury Academic Article
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Conformational Changes in Bcl-2 Pro-survival Proteins Determine Their Capacity to Bind Ligands Academic Article
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Conservation of baculovirus inhibitor of apoptosis repeat proteins (BIRPs) in viruses, nematodes, vertebrates and yeasts Academic Article
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Control of Apoptosis in Hematopoietic Cells by the Bcl-2 Family of Proteins Conference Paper
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Controlling TRAIL-mediated caspase-3 activation Academic Article
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Conversion of Bim-BH3 from activator to inhibitor of Bak through structure-based design Academic Article
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Cre transgene results in global attenuation of the cAMP/PKA pathway Academic Article
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CrmA expression in T lymphocytes of transgenic mice inhibits CD95 (Fas/APO-1)-transduced apoptosis, but does not cause lymphadenopathy or autoimmune disease. Academic Article
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Crosstalk between apoptosis and autophagy signaling pathways Chapter
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Crystal structure of ABT-737 complexed with Bcl-xL: implications for selectivity of antagonists of the Bcl-2 family Academic Article
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Cyclic‐AMP‐dependent protein kinase A regulates apoptosis by stabilizing the BH3‐only protein Bim Academic Article
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Cycloheximide can induce Bax/Bak dependent myeloid cell death independently of multiple BH3-only proteins Academic Article
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Cytoplasmic p53 is not required for PUMA-induced apoptosis Academic Article
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Cytotoxic T lymphocyte–induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis Academic Article
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DR5 and caspase-8 are dispensable in ER stress-induced apoptosis Academic Article
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Death in the snow: report on Keystone Conference on ‘Apoptosis and Programmed Cell Death’ at Breckenridge, CO, April 6–11th 1999 Conference Paper
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Death to flies: Drosophila as a model system to study programmed cell death Academic Article
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Debcl, a Proapoptotic Bcl-2 Homologue, Is a Component of the Drosophila melanogaster Cell Death Machinery Academic Article
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Deerpox Virus Encodes an Inhibitor of Apoptosis That Regulates Bak and Bax Academic Article
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Defining the morphologic features and products of cell disassembly during apoptosis Letter
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Defining the role of cytoskeletal components in the formation of apoptopodia and apoptotic bodies during apoptosis Academic Article
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Deglycosylated bleomycin induces apoptosis in lymphoma cell via c-jun NH2-terminal kinase but not reactive oxygen species Academic Article
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Degranulation of mast cells induced by gastric cancer-derived adrenomedullin prompts gastric cancer progression Academic Article
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Destruction of tumor vasculature and abated tumor growth upon VEGF blockade is driven by proapoptotic protein Bim in endothelial cells Academic Article
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Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance Academic Article
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Determining the contents and cell origins of apoptotic bodies by flow cytometry Academic Article
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Developmental and Neuropathological Consequences of Ductal Ligation in the Preterm Baboon Academic Article
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Diabetic cardiomyopathy: Mechanisms and new treatment strategies targeting antioxidant signaling pathways Academic Article
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Diablo Promotes Apoptosis by Removing Miha/Xiap from Processed Caspase 9 Academic Article
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Differential Inhibition of TRAIL-Mediated DR5-DISC Formation by Decoy Receptors 1 and 2 Academic Article
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Differential Regulation of Gastric Tumor Growth by Cytokines That Signal Exclusively Through the Coreceptor gp130 Academic Article
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Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Ligands Allows Complementary Apoptotic Function Academic Article
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Differential regulation of Nedd4 ubiquitin ligases and their adaptor protein Ndfip1 in a rat model of ischemic stroke Academic Article
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Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP Academic Article
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Direct visualization of Bcl-2 family protein interactions using live cell fluorescent protein redistribution assays Academic Article
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Disassembly of dying cells in diverse organisms Academic Article
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Disassembly of the Dying: Mechanisms and Functions Academic Article
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Discordant Regulation of Granzyme H and Granzyme B Expression in Human Lymphocytes Academic Article
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Discovery and molecular characterization of a Bcl-2-regulated cell death pathway in schistosomes Academic Article
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Discovery of potent and selective benzothiazole hydrazone inhibitors of Bcl-XL Academic Article
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Dissection of Protease-Activated Receptor-1-Dependent and -Independent Responses to Thrombin in Skeletal Myoblasts Academic Article
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Dissociation of Pentameric to Monomeric C-Reactive Protein on Activated Platelets Localizes Inflammation to Atherosclerotic Plaques Academic Article
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Dissociation of staurosporine-induced apoptosis from G2-M arrest in SW620 human colonic carcinoma cells: Initiation of the apoptotic cascade is associated with elevation of the mitochondrial membrane potential (Δψ(m)) Academic Article
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Disturbed oligodendrocyte development and recovery from hypomyelination in a c-myc transgenic mouse mutant Academic Article
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Divergent phenotypic patterns and commitment to apoptosis of Caco-2 cells during spontaneous and butyrate-induced differentiation Academic Article
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Diverging impact of cell fate determinants Scrib and Llgl1 on adhesion and migration of hematopoietic stem cells Academic Article
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Doxorubicin-DNA Adducts Induce a Non-Topoisomerase II–Mediated Form of Cell Death Academic Article
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Drosophila SPARC Is a Self-Protective Signal Expressed by Loser Cells during Cell Competition Academic Article
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Dual inhibition of BCL-XL and MCL-1 is required to induce tumour regression in lung squamous cell carcinomas sensitive to FGFR inhibition Academic Article
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EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival Academic Article
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ER Stress Triggers Apoptosis by Activating BH3-Only Protein Bim Academic Article
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ER Stress and UPR in Familial Amyotrophic Lateral Sclerosis Academic Article
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ERp57 is protective against mutant SOD1-induced cellular pathology in amyotrophic lateral sclerosis Academic Article
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Early origins of heart disease: Low birth weight and determinants of cardiomyocyte endowment Academic Article
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Early work on the function of Bcl-2, an interview with David Vaux Academic Article
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Effect of immunosuppressive agents on hepatocyte apoptosis post-liver transplantation Academic Article
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Effect of oxysterols on hematopoietic progenitor cells Academic Article
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Effects of viral inhibitors of apoptosis in models of mammalian cell death. Academic Article
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Eicosapentaenoic acid in combination with EPHA2 inhibition shows efficacy in preclinical models of triple-negative breast cancer by disrupting cellular cholesterol efflux Academic Article
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Enantioselective Synthesis of Ferrocenyl Nucleoside Analogues with Apoptosis-Inducing Activity Academic Article
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Endogenous bcl-2 is not required for the development of Eμ-myc–induced B-cell lymphoma Academic Article
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Endothelial cell apoptosis and the role of endothelial cell-derived extracellular vesicles in the progression of atherosclerosis Academic Article
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Enhancement of anticancer activity by silibinin and paclitaxel combination on the ovarian cancer Academic Article
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Entamoeba histolytica: Target Cells Killed by Trophozoites Undergo DNA Fragmentation Which Is Not Blocked by Bcl-2 Academic Article
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EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation Academic Article
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Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 Academic Article
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Establishment of primary cultures of rat olfactory bulb under serum-free conditions for studies of cellular injury Academic Article
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Evidence for a detrimental role of TLR8 in ischemic stroke Academic Article
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Evidence of the TNF-α system in the human achilles tendon: Expression of TNF-α and TNF receptor at both protein and mRNA levels in the tenocytes Academic Article
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Evidence that NLRC4 inflammasome mediates apoptotic and pyroptotic microglial death following ischemic stroke Academic Article
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Evolutionary divergence of the necroptosis effector MLKL Academic Article
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Ex vivo pediatric brain tumors express Fas (CD95) and FasL (CD95L) and are resistant to apoptosis induction Academic Article
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Executioner caspases and CAD are essential for mutagenesis induced by TRAIL or vincristine Academic Article
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Exosomes: Extracellular organelles important in intercellular communication Academic Article
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Expanded Granulocyte/Monocyte Compartment in Myeloid-Specific Triple FoxO Knockout Increases Oxidative Stress and Accelerates Atherosclerosis in Mice Academic Article
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Experimental in vivo sepsis models to monitor immune cell apoptosis and survival in laboratory mice Chapter
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Expression of candidate cell death genes in cell lines during apoptosis Academic Article
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Expression of secreted frizzled-related protein 4 in the primate placenta Academic Article
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Extracellular HtrA2 induces apoptosis in human umbilical vein endothelial cells Academic Article
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Extracellular wildtype and mutant SOD1 induces ER–Golgi pathology characteristic of amyotrophic lateral sclerosis in neuronal cells Academic Article
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FOXP3 over-expression inhibits melanoma tumorigenesis via effects on proliferation and apoptosis. Academic Article
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Fatal Hepatitis Mediated by Tumor Necrosis Factor TNFα Requires Caspase-8 and Involves the BH3-Only Proteins Bid and Bim Academic Article
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Fibroblasts derived from Gpx1 knockout mice display senescent-like features and are susceptible to H2O2-mediated cell death Academic Article
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Focus on extracellular vesicles: introducing the next small big thing Academic Article
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Fold up or perish: unfolded protein response and chemotherapy Academic Article
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Formaldehyde-releasing prodrugs specifically affect cancer cells by depletion of intracellular glutathione and augmentation of reactive oxygen species Academic Article
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Function of microRNA-143 in different signal pathways in cancer: New insights into cancer therapy Academic Article
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Functional and biochemical characterization of the baculovirus caspase inhibitor MaviP35 Academic Article
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Functional regulation of the plasma protein histidine-rich glycoprotein by ZN2+ in settings of tissue injury Academic Article
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Further Insights into the Effects of Pre-organizing the BimBH3 Helix [Addendum ] Erratum
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Gamma secretase–mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke Academic Article
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Gasdermin E Does Not Limit Apoptotic Cell Disassembly by Promoting Early Onset of Secondary Necrosis in Jurkat T Cells and THP-1 Monocytes Academic Article
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Gene expression profiling of intestinal epithelial cell maturation along the crypt-villus axis Academic Article
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Gold and Silver Nanoparticles Biomimetically Synthesized Using Date Palm Pollen Extract-Induce Apoptosis and Regulate p53 and Bcl-2 Expression in Human Breast Adenocarcinoma Cells Academic Article
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Gp130-dependent astrocytic survival is critical for the control of autoimmune central nervous system inflammation Academic Article
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Granzyme M Mediates a Novel Form of Perforin-dependent Cell Death Academic Article
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Group A Streptococcus Modulates Host Inflammation by Manipulating Polymorphonuclear Leukocyte Cell Death Responses Academic Article
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Growth suppression of intracranial xenografted glioblastomas overexpressing mutant epidermal growth factor receptors by systemic administration of monoclonal antibody (mAb) 806, a novel monoclonal antibody directed to the receptor Academic Article
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Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes Academic Article
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HDAC inhibitors induce tumor-cell-selective pro-apoptotic transcriptional responses Academic Article
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HDAC4 Promotes Growth of Colon Cancer Cells via Repression of p21 Academic Article
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HDACs and HDAC inhibitors in colon cancer Academic Article
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HOIP deficiency causes embryonic lethality by aberrant TNFR1-mediated endothelial cell death Academic Article
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HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death Academic Article
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Heat Shock Protein 72 Modulates Pathways of Stress-induced Apoptosis Academic Article
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Hepatitis C virus-induced hepatocyte cell death and protection by inhibition of apoptosis Academic Article
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Hepatitis C-induced hepatocyte apoptosis following liver transplantation is enhanced by immunosuppressive agents Academic Article
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Hepatocyte growth factor renders BRAF mutant human melanoma cell lines resistant to PLX4032 by downregulating the pro-apoptotic BH3-only proteins PUMA and BIM Academic Article
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Heritable pathologic cardiac hypertrophy in adulthood is preceded by neonatal cardiac growth restriction Academic Article
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High strain mechanical loading rapidly induces tendon apoptosis: an ex vivo rat tibialis anterior model Academic Article
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High-throughput screens identify HSP90 inhibitors as potent therapeutics that target inter-related growth and survival pathways in advanced prostate cancer Academic Article
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Histidine-rich Glycoprotein Specifically Binds to Necrotic Cells via Its Amino-terminal Domain and Facilitates Necrotic Cell Phagocytosis Academic Article
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Histone Deacetylase 3 (HDAC3) and Other Class I HDACs Regulate Colon Cell Maturation and p21 Expression and Are Deregulated in Human Colon Cancer Academic Article
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Hoxb8 regulates expression of microRNAs to control cell death and differentiation Academic Article
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Hsp70 Architecture: The Formation of Novel Polymeric Structures of Hsp70.1 and Hsc70 after Proteotoxic Stress Academic Article
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Hsp72 Inhibits Apoptosis Upstream of the Mitochondria and Not through Interactions with Apaf-1 Academic Article
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Hsp72 Inhibits Fas-mediated Apoptosis Upstream of the Mitochondria in Type II Cells Academic Article
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Hsp72 chaperone function is dispensable for protection against stress-induced apoptosis Academic Article
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HtrA2 Promotes Cell Death through Its Serine Protease Activity and Its Ability to Antagonize Inhibitor of Apoptosis Proteins Academic Article
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HtrA2/Omi, a Sheep in Wolf's Clothing Academic Article
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Human Bcl-2 cannot directly inhibit the Caenorhabditis elegans Apaf-1 homologue CED-4, but can interact with EGL-1 Academic Article
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Human beta-defensin 3 contains an oncolytic motif that binds PI(4,5)P-2 to mediate tumour cell permeabilisation Academic Article
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Human telomerase reverse transcriptase protects hematopoietic progenitor TF-1 cells from death and quiescence induced by cytokine withdrawal Academic Article
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Human, insect and nematode caspases kill Saccharomyces cerevisiae independently of YCA1 and Aif1p Academic Article
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Hurpin Is a Selective Inhibitor of Lysosomal Cathepsin L and Protects Keratinocytes from Ultraviolet-Induced Apoptosis† Academic Article
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Hypoxia Enhances the Proliferative Response of Macrophages to CSF-1 and Their Pro-Survival Response to TNF Academic Article
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IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis Academic Article
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IAP Family of Cell Death and Signaling Regulators Chapter
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IAPS and ubiquitylation Academic Article
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IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-κB as well as cell survival and oncogenesis Academic Article
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IL-6 Regulates Neutrophil Trafficking during Acute Inflammation via STAT3 Academic Article
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IMiDs prime myeloma cells for daratumumab-mediated cytotoxicity through loss of Ikaros and Aiolos Academic Article
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Identification of DIABLO, a Mammalian Protein that Promotes Apoptosis by Binding to and Antagonizing IAP Proteins Academic Article
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Identification of an activation site in Bak and mitochondrial Bax triggered by antibodies Academic Article
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Immunopathology of apoptosis ?introduction and overview Academic Article
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Impact of conditional deletion of the pro-apoptotic BCL-2 family member BIM in mice Academic Article
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In Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1-Rok-Myosin-II and JNK signalling Academic Article
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In mouse embryonic fibroblasts, neither caspase-8 nor cellular FLICE-inhibitory protein (FLIP) is necessary for TNF to activate NF-κB, but caspase-8 is required for TNF to cause cell death, and induction of FLIP by NF-κB is required to prevent it Academic Article
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In the absence of apoptosis, myeloid cells arrest when deprived of growth factor, but remain viable by consuming extracellular glucose Academic Article
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In vitro and in vivo evaluation of the influence of type III NaPi co-transporter activity during apoptosis on 99mTc-(V)DMSA uptake in the human leukaemic cell line U937 Academic Article
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Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury Academic Article
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Induction of apoptosis by plant natriuretic peptides in rat cardiomyoblasts Academic Article
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Inflammasome adaptor ASC suppresses apoptosis of gastric cancer cells by an IL18-mediated inflammation-independent mechanism Academic Article
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Inflammation and depression: Why poststroke depression may be the norm and not the exception Academic Article
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Inhibition of Bak Activation by VDAC2 Is Dependent on the Bak Transmembrane Anchor Academic Article
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Inhibition of Bcl-2 or IAP proteins does not provoke mutations in surviving cells Academic Article
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Inhibition of apoptosis and clonogenic survival of cells expressing crmA variants: optimal caspase substrates are not necessarily optimal inhibitors Academic Article
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Inhibition of cathepsin proteases attenuates migration and sensitizes aggressive N-Myc amplified human neuroblastoma cells to doxorubicin Academic Article
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Inhibition of interleukin 1 -converting enzyme-mediated apoptosis of mammalian cells by baculovirus IAP Conference Paper
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Inhibition of osteoblast apoptosis by thrombin Academic Article
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Inhibitor of Apoptosis (IAP) Proteins-Modulators of Cell Death and Inflammation Academic Article
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Inhibitor of Apoptosis Proteins Limit RIP3 Kinase-Dependent Interleukin-1 Activation Academic Article
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Inhibitor of apoptosis protein (IAP) antagonists demonstrate divergent immunomodulatory properties in human immune subsets with implications for combination therapy Academic Article
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Inhibitor of apoptosis protein-1 regulates tumor necrosis factor-mediated destruction of intestinal epithelial cells Academic Article
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Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs Academic Article
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Insights from Bcl-2 and Myc: Malignancy Involves Abrogation of Apoptosis as well as Sustained Proliferation Conference Paper
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Intravenous immunoglobulin (IVIg) dampens neuronal toll-like receptor-mediated responses in ischemia Academic Article
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Isolation of cell type-specific apoptotic bodies by fluorescence-activated cell sorting Academic Article
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Kainate-induced apoptosis correlates with c-Jun activation in cultured cerebellar granule cells Academic Article
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Molecular Mechanisms of Apoptosis: An Overview Academic Article
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Mouse granzyme A induces a novel death with writhing morphology that is mechanistically distinct from granzyme B-induced apoptosis Academic Article
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NADPH oxidase isoform selective regulation of endothelial cell proliferation and survival Academic Article
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Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted Academic Article
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Nedd4-WW Domain-Binding Protein 5 (Ndfip1) Is Associated with Neuronal Survival after Acute Cortical Brain Injury Academic Article
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Neither macromolecular synthesis nor myc is required for cell death via the mechanism that can be controlled by Bcl-2. Academic Article
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Neuronal low-density lipoprotein receptor-related protein 1 (LRP1) enhances the anti-apoptotic effect of intravenous immunoglobulin (IVIg) in ischemic stroke Academic Article
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Neuronal oxidative stress in acute ischemic stroke: sources and contribution to cell injury Academic Article
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Normoxic regulation of HIF-1α in prostate cancer Letter
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Oncolytic reovirus preferentially induces apoptosis in KRAS mutant colorectal cancer cells, and synergizes with irinotecan Academic Article
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Ontogenetic Changes in Retinal Ganglion Cell Distribution and Spatial Resolving Power in the Brown-Banded Bamboo Shark Chiloscyllium punctatum (Elasmobranchii) Academic Article
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Over-Expression of DSCR1 Protects against Post-Ischemic Neuronal Injury Academic Article
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Over-expression of insulin-like growth factor binding protein-related protein-1(IGFBP-rP1/mac25) in the M12 prostate cancer cell line alters tumor growth by a delay in G1 and cyclin A associated apoptosis Academic Article
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Overexpression of Endogenous Anti-Oxidants with Selenium Supplementation Protects Trophoblast Cells from Reactive Oxygen Species-Induced Apoptosis in a Bcl-2-Dependent Manner Academic Article
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PD-L1 and IAPs co-operate to protect tumors from cytotoxic lymphocyte-derived TNF Academic Article
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PSGL-1-Mediated Adhesion of Human Hematopoietic Progenitors to P-Selectin Results in Suppression of Hematopoiesis Academic Article
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Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack Academic Article
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Pin1 promotes neuronal death in stroke by stabilizing notch intracellular domain Academic Article
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Plexin B2 is a regulator of monocyte apoptotic cell disassembly Academic Article
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Plumbagin Downregulates Wnt Signaling Independent of p53 in Human Colorectal Cancer Cells Academic Article
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Postchemotherapy and Tumor-Selective Targeting with the La-Specific DAB4 Monoclonal Antibody Relates to Apoptotic Cell Clearance Academic Article
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Potent efficacy of MCL-1 inhibitor-based therapies in preclinical models of mantle cell lymphoma Academic Article
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Pro-apoptotic Bim suppresses breast tumor cell metastasis and is a target gene of SNAI2 Academic Article
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Proapoptotic Bcl-2 family member Bim is involved in the control of mast cell survival and is induced together with Bcl-XL upon IgE-receptor activation Academic Article
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Programmed Anuclear Cell Death Delimits Platelet Life Span Academic Article
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Programmed cell death: Superman meets Dr Death Conference Paper
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Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak Academic Article
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Prosurvival Bcl-2 family members reveal a distinct apoptotic identity between conventional and plasmacytoid dendritic cells Academic Article
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Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Academic Article
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Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim Academic Article
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Quinazoline Sulfonamides as Dual Binders of the Proteins B-Cell Lymphoma 2 and B-Cell Lymphoma Extra Long with Potent Proapoptotic Cell-Based Activity Academic Article
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RIP-in CD95-induced cell death: The control of alternative death receptors pathways by cIAPs Academic Article
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RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation Academic Article
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RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development Academic Article
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RIPK1-and RIPK3-induced cell death mode is determined by target availability Academic Article
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Recent Advances in Understanding and Exploiting the Activation of Anthracyclines by Formaldehyde Academic Article
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Recruitment of mitochondria into apoptotic signaling correlates with the presence of inclusions formed by amyotrophic lateral sclerosis-associated SOD1 mutations Academic Article
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SIRT2 inhibition confers neuroprotection by downregulation of FOXO3a and MAPK signaling pathways in ischemic stroke Academic Article
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STRICA, a novel Drosophila melanogaster caspase with an unusual serine/threonine-rich prodomain, interacts with DIAP1 and DIAP2 Academic Article
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Selective inhibition of endogenous antioxidants with Auranofin causes mitochondrial oxidative stress which can be countered by selenium supplementation Academic Article
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Sequence as well as functional similarity for DIABLO/Smac and Grim, Reaper and Hid? Academic Article
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Sublethal Concentrations of Prion Peptide PrP106–126 or the Amyloid Beta Peptide of Alzheimer's Disease Activates Expression of Proapoptotic Markers in Primary Cortical Neurons Academic Article
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TRAIL and Malignant Glioma Academic Article
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TRAIL-induced apoptosis is enhanced by heat shock protein 70 expression Academic Article
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Targeting EphA3 inhibits cancer growth by disrupting the tumor stromal microenvironment Academic Article
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Targeting XIAP and PPARγ in granulosa cell tumors alters metabolic signaling Academic Article
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Targeting neuropilin-1 in human leukemia and lymphoma Academic Article
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Targeting the upregulation of reactive oxygen species subsequent to hyperglycemia prevents type 1 diabetic cardiomyopathy in mice Academic Article
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Tenocyte responses to mechanical loading in vivo - A role for local insulin-like growth factor 1 signaling in early tendinosis in rats Academic Article
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Tenocyte responses to mechanical loading in vivo: A role for local insulin-like growth factor 1 signaling in early tendinosis in rats Academic Article
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The Bcl-2 family in host-virus interactions Academic Article
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The Bcl-2 family: structures, interactions and targets for drug discovery Academic Article
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The Carboxyl-Terminal Domain of Inducible Hsp70 Protects from Ischemic Injuryin vivoandin vitro Academic Article
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The Drosophila Caspase Inhibitor DIAP1 Is Essential for Cell Survival and Is Negatively Regulated by HID Academic Article
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The Drosophila caspase DRONC is a glutamate/aspartate protease whose activity is regulated by DIAP1, HID and GRIM Academic Article
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The Drosophila caspase DRONC is regulated by DIAP1 Academic Article
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The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation Academic Article
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The Structural Biology of BH3-Only Proteins Academic Article
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The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3– and caspase 9–interacting sites Academic Article
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The brace helices of MLKL mediate interdomain communication and oligomerisation to regulate cell death by necroptosis Academic Article
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The co-regulator dNAB interacts with Brinker to eliminate cells with reduced Dpp signaling Academic Article
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The functional differences between pro-survival and pro-apoptotic B cell lymphoma 2 (Bcl-2) proteins depend on structural differences in their Bcl-2 homology 3 (BH3) domains Academic Article
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The importance of being chaperoned: HSP90 and necroptosis Editorial Article
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The molecular biology of apoptosis. Academic Article
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The p35 relative, p49, inhibits mammalian and Drosophila caspases including DRONC and protects against apoptosis Academic Article
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The polycomb repressive complex 2 governs life and death of peripheral T cells Academic Article
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The proto-oncogene Ret is required for male foetal germ cell survival Academic Article
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The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism Academic Article
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The restricted binding repertoire of Bcl-B leaves Bim as the universal BH3-only prosurvival Bcl-2 protein antagonist Academic Article
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The role of BH3-only protein Bim extends beyond inhibiting Bcl-2–like prosurvival proteins Academic Article
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The role of the Bcl-2 family of apoptosis regulatory proteins in the immune system Academic Article
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The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy Academic Article
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The small molecule that packs a punch: ubiquitin-mediated regulation of RIPK1/FADD/caspase-8 complexes Academic Article
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Therapeutic anti-EGFR antibody 806 generates responses in murine de novo EGFR mutant–dependent lung carcinomas Academic Article
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Therapeutic efficacy of177Lu-CHX-A″-DTPA-hu3S193 radioimmunotherapy in prostate cancer is enhanced by EGFR inhibition or docetaxel chemotherapy Academic Article
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Therapeutic inhibition of Jak activity inhibits progression of gastrointestinal tumors in mice Academic Article
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Thirty years of BCL-2: translating cell death discoveries into novel cancer therapies Academic Article
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Till Death Do Us Part Academic Article
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To Trigger Apoptosis, Bak Exposes Its BH3 Domain and Homodimerizes via BH3:Groove Interactions Academic Article
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Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid β-peptide and the membrane lipid peroxidation product 4-hydroxynonenal Academic Article
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Toward an understanding of the molecular mechanisms of physiological cell death. Academic Article
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Transduction of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand into Hematopoietic Cells Leads to Inhibition of Syngeneic Tumor Growth In vivo Academic Article
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Triggering of Apoptosis by Puma Is Determined by the Threshold Set by Prosurvival Bcl-2 Family Proteins Academic Article
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Tumor Cell Response to Synchrotron Microbeam Radiation Therapy Differs Markedly From Cells in Normal Tissues Academic Article
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Tumor Necrosis Factor (TNF) Signaling, but Not TWEAK (TNF-like Weak Inducer of Apoptosis)-triggered cIAP1 (Cellular Inhibitor of Apoptosis Protein 1) Degradation, Requires cIAP1 RING Dimerization and E2 Binding Academic Article
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Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2 Academic Article
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Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands Academic Article
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