subject area of
- A hypermorphic epithelial beta-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations Academic Article
- AACR special meeting in cancer research: Colon cancer-genetics to prevention Conference Paper
- ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling Academic Article
- Age and sex differences in human skeletal muscle fibrosis markers and transforming growth factor-β signaling Academic Article
- Butyrate-induced apoptotic cascade in colonic carcinoma cells: Modulation of the β-catenin-Tcf pathway and concordance with effects of sulindac and trichostatin A but not curcumin Academic Article
- Disease-associated mutations in IRF6 and RIPK4 dysregulate their signalling functions Academic Article
- Down-regulation of β-catenin TCF signaling is linked to colonic epithelial cell differentiation Academic Article
- Genetic Dissection of Differential Signaling Threshold Requirements for the Wnt/β-Catenin Pathway In Vivo Academic Article
- Identification of a Wnt-induced protein complex by affinity proteomics using an antibody that recognizes a sub-population of β-catenin Academic Article
- In MMTV-Her-2/neu transgenic mammary tumors the absence of caveolin-1 -/- alters PTEN and NHERF1 but not β-catenin expression Academic Article
- In situ phosphorylation of immobilized receptors on biosensor surfaces: Application to E-cadherin/β-catenin interactions Academic Article
- Intestinal adenoma formation and MYC activation are regulated by cooperation between MYB and Wnt signaling Academic Article
- Intestinal epithelial-specific PTEN inactivation results in tumor formation Academic Article
- JRK is a positive regulator of β-catenin transcriptional activity commonly overexpressed in colon, breast and ovarian cancer Academic Article
- Olig2-Induced Neural Stem Cell Differentiation Involves Downregulation of Wnt Signaling and Induction of Dickkopf-1 Expression Academic Article
- Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-β-catenin-mediated intestinal tumor growth and regeneration Academic Article
- Plumbagin Downregulates Wnt Signaling Independent of p53 in Human Colorectal Cancer Cells Academic Article
- RHOA inactivation enhances Wnt signalling and promotes colorectal cancer Academic Article
- Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth Academic Article
- Response of Apcmin and A33ΔNβ-cat mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) Academic Article
- Restoration of full-length adenomatous polyposis coli (APC) protein in a colon cancer cell line enhances cell adhesion Academic Article
- Scribble Interacts with β-Catenin to Localize Synaptic Vesicles to Synapses Academic Article
- Short Chain Fatty Acids and Colon Cancer Conference Paper
- Solubilisation of the armadillo-repeat protein β-catenin using a zwitterionic detergent allows resolution of phosphorylated forms by 2DE Academic Article
- Variable FZD7 expression in colorectal cancers indicates regulation by the tumour microenvironment Academic Article
- β-Catenin/Tcf-4 Inhibition After Progastrin Targeting Reduces Growth and Drives Differentiation of Intestinal Tumors Academic Article
- β-catenin negatively regulates expression of the prostaglandin transporter PGT in the normal intestinal epithelium and colorectal tumour cells: A role in the chemopreventive efficacy of aspirin Academic Article
- β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells Academic Article