subject area of
- A novel synthetic small molecule DMFO targets Nrf2 in modulating proinflammatory/antioxidant mediators to ameliorate inflammation Academic Article
- ABT-737 overcomes Bcl-2 mediated resistance to doxorubicin–DNA adducts Academic Article
- ABT-737, proving to be a great tool even before it is proven in the clinic Academic Article
- Assessment of antioxidant activity in Victorian marine algal extracts using high performance thin-layer chromatography and multivariate analysis Academic Article
- BAX-BAK1-independent LC3B lipidation by BH3 mimetics is unrelated to BH3 mimetic activity and has only minimal effects on autophagic flux Academic Article
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Bcl-2, Bcl-x
L , and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells Academic Article - Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic Academic Article
- CLL cells are resistant to smac mimetics because of an inability to form a ripoptosome complex. Academic Article
- Comprehensive sample analysis using high performance liquid chromatography with multi-detection Academic Article
- Conformational Changes in Bcl-2 Pro-survival Proteins Determine Their Capacity to Bind Ligands Academic Article
- Conformational analogues of Oxamflatin as histone deacetylase inhibitors Academic Article
- Crystal structure of ABT-737 complexed with Bcl-xL: implications for selectivity of antagonists of the Bcl-2 family Academic Article
- Defining the target specificity of ABT-737 and synergistic antitumor activities in combination with histone deacetylase inhibitors Academic Article
- Development and validation of a simple high performance thin layer chromatography method combined with direct 1,1-diphenyl-2-picrylhydrazyl assay to quantify free radical scavenging activity in wine Academic Article
- Discovery and molecular characterization of a Bcl-2-regulated cell death pathway in schistosomes Academic Article
- Effect of Central Endogenous Angiotensin II on Sympathetic Activation Induced by Hypoxia Conference Paper
- Fluorescence enhancements of benzene-cored luminophors by restricted intramolecular rotations: AIE and AIEE effects Academic Article
- Gefitinib-Induced Killing of NSCLC Cell Lines Expressing Mutant EGFR Requires BIM and Can Be Enhanced by BH3 Mimetics Academic Article
- HPTLC based approach for bioassay-guided evaluation of antidiabetic and neuroprotective effects of eight essential oils of the Lamiaceae family plants Academic Article
- High performance liquid chromatography with two simultaneous on-line antioxidant assays: Evaluation and comparison of espresso coffees Academic Article
- High-Performance Thin-Layer Chromatography Hyphenated with Microchemical and Biochemical Derivatizations in Bioactivity Profiling of Marine Species Academic Article
- High-performance liquid chromatography with post-column 2,2′-diphenyl-1-picrylhydrazyl radical scavenging assay: Methodological considerations and application to complex samples Academic Article
- High-performance thin-layer chromatographic methods in the evaluation of the antioxidant and anti-hyperglycemic activity of Myrmecodia platytyrea as a promising opportunity in diabetes treatment Academic Article
- Induction of Fibrinogen Binding and Platelet Aggregation as a Potential Intrinsic Property of Various Glycoprotein IIb/IIIa (IIbβ3) Inhibitors Academic Article
- Inhibition of Bcl-2 or IAP proteins does not provoke mutations in surviving cells Academic Article
- Mcl-1 and Bcl-xL coordinately regulate megakaryocyte survival Academic Article
- Mcl-1 and Bcl-xL sequestration of Bak confers differential resistance to BH3-only proteins Academic Article
- Mutation to bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosis Academic Article
- Preparing samples for crystallization of Bcl-2 family complexes Chapter
- Probing into the Molecular Requirements for Antioxidant Activity in Plant Phenolic Compounds Utilizing a Combined Strategy of PCA and ANN Academic Article
- Programmed Anuclear Cell Death Delimits Platelet Life Span Academic Article
- Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak Academic Article
- Screening for antioxidants in complex matrices using high performance liquid chromatography with acidic potassium permanganate chemiluminescence detection Academic Article
- Subversion of the Bcl-2 Life/Death Switch in Cancer Development and Therapy Conference Paper
- Targeting BCL-2 with the BH3 mimetic ABT-199 in estrogen receptor-positive breast cancer Academic Article
- The BH3 mimetic compound, ABT-737, synergizes with a range of cytotoxic chemotherapy agents in chronic lymphocytic leukemia Academic Article
- Thirty years of BCL-2: translating cell death discoveries into novel cancer therapies Academic Article
- Two routes of iron accumulation in astrocytes: ascorbate-dependent ferrous iron uptake via the divalent metal transporter (DMT1) plus an independent route for ferric iron Academic Article
- Yeast techniques for modeling drugs targeting Bcl-2 and caspase family members Academic Article