subject area of

• A Bispecific Antifibrin-antiplatelet Urokinase Conjugate (BAAUC) Induces Enhanced Clot Lysis and Inhibits Platelet Aggregation  Academic Article
• A Unique Recombinant Fluoroprobe Targeting Activated Platelets Allows In Vivo Detection of Arterial Thrombosis and Pulmonary Embolism Using a Novel Three-Dimensional Fluorescence Emission Computed Tomography (FLECT) Technology  Academic Article
• A critical role for the transcription factor Scl in platelet production during stress thrombopoiesis  Academic Article
• A molecular intravascular ultrasound contrast agent allows detection of activated platelets on the surface of symptomatic human plaques  Academic Article
• A reversed-phase HPLC-based method for the assay of cyclic nucleotide phosphodiesterase activity  Academic Article
• A transgenic mouse model to inducibly target prosurvival Bcl2 proteins with selective BH3 peptides in vivo [letter]  Academic Article
• Activated platelets in the tumor microenvironment for targeting of antibody-drug conjugates to tumors and metastases  Academic Article
• Activating Effects of GPIIb/IIIa Blockers: An Intrinsic Consequence of Ligand- Mimetic Properties  Academic Article
• Activation of protease-activated receptors by gingipains fromPorphyromonas gingivalis leads to platelet aggregation: a new trait in microbial pathogenicity  Academic Article
• Altered platelet alpha 2-adrenergic binding sites in posttraumatic stress disorder  Academic Article
• Altered platelet alpha 2-adrenergic receptor binding sites in borderline personality disorder  Academic Article
• An interaction map of circulating metabolites, immune gene networks, and their genetic regulation  Academic Article
• Atherosclerosis proceeds independently of thrombin-induced platelet activation in ApoE−/− mice  Academic Article
• Atherosclerotic Plaque Rupture  Academic Article
• Bacterial testing of platelets – has it prevented transfusion-transmitted bacterial infections in Australia?  Academic Article
• Biomanufacture of human platelets for transfusion: Rationale and approaches  Academic Article
• C-reactive protein: How conformational changes influence inflammatory properties  Academic Article
• Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis  Academic Article
• CliniMACS CD34-selected cells to support multiple cycles of high-dose therapy  Academic Article
• Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis  Academic Article
• Combined deficiency of PI3KC2α and PI3KC2β reveals a nonredundant role for PI3KC2α in regulating mouse platelet structure and thrombus stability  Academic Article
• Compensatory mechanisms in platelet production: The response of Sl/Sl(d) mice to 5-fluorouracil  Academic Article
• Conformation-Specific Blockade of the Integrin GPIIb/IIIa  Academic Article
• Contributions of LFA-1 and Mac-1 to brain injury and microvascular dysfunction induced by transient middle cerebral artery occlusion  Academic Article
• Critical temperature ranges of hypothermia-induced platelet activation: Possible implications for cooling patients in cardiac surgery  Academic Article
• Current and future antiplatelet therapies: emphasis on preserving haemostasis  Academic Article
• Deficiency of ATP-Binding Cassette Transporter B6 in Megakaryocyte Progenitors Accelerates Atherosclerosis in Mice  Academic Article
• Delayed targeting of CD39 to activated platelet GPIIb/IIIa via a single-chain antibody: breaking the link between antithrombotic potency and bleeding?  Academic Article
• Development of a novel strategy to target CD39 antithrombotic activity to the endothelial-platelet microenvironment in kidney ischemia–reperfusion injury  Academic Article
• Disordered haematopoiesis and athero-thrombosis  Academic Article
• Dissociation of Pentameric to Monomeric C-Reactive Protein on Activated Platelets Localizes Inflammation to Atherosclerotic Plaques  Academic Article
• Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage  Academic Article
• Dual targeting improves capture of ultrasound microbubbles towards activated platelets but yields no additional benefit for imaging of arterial thrombosis  Academic Article
• Dual-contrast molecular imaging allows noninvasive characterization of myocardial ischemia/reperfusion injury after coronary vessel occlusion in mice by magnetic resonance imaging  Academic Article
• Enrichment of Human Platelet Membranes for Proteomic Analysis  Academic Article
• Enzymatic Single-Chain Antibody Tagging  Academic Article
• Evidence of Platelet Activation at Medically Used Hypothermia and Mechanistic Data Indicating ADP as a Key Mediator and Therapeutic Target  Academic Article
• Flow Cytometric Monitoring of Glycoprotein IIb/IIIa Blockade and Platelet Function in Patients With Acute Myocardial Infarction Receiving Reteplase, Abciximab, and Ticlopidine  Academic Article
• Forget about thrombosis: Platelets and Alzheimer’s disease, yet another sticky situation  Academic Article
• Functionalized Magnetic Resonance Contrast Agent Selectively Binds to Glycoprotein IIb/IIIa on Activated Human Platelets under Flow Conditions and Is Detectable at Clinically Relevant Field Strengths  Academic Article
• GPIIb/IIIa inhibitors: From bench to bedside and back to bench again  Academic Article
• GPVI and GPIbα Mediate Staphylococcal Superantigen-Like Protein 5 (SSL5) Induced Platelet Activation and Direct toward Glycans as Potential Inhibitors  Academic Article
• Glycoprotein VI is associated with GPIb-IX-V on the membrane of resting and activated platelets  Academic Article
• HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi  Academic Article
• Highly Sensitive Detection of Minimal Cardiac Ischemia using Positron Emission Tomography Imaging of Activated Platelets  Academic Article
• Immuno-magnetoliposomes targeting activated platelets as a potentially human-compatible MRI contrast agent for targeting atherothrombosis  Academic Article
• Impaired platelet nitric oxide response in patients with new onset atrial fibrillation  Academic Article
• Inflammation in acute coronary syndrome: Expression of TLR2 mRNA is increased in platelets of patients with ACS  Academic Article
• Inhaled Nitric Oxide Inhibits Human Platelet Aggregation, P-Selectin Expression, and Fibrinogen Binding In Vitro and In Vivo  Academic Article
• Intrinsic apoptosis circumvents the functional decline of circulating platelets but does not cause the storage lesion  Academic Article
• It's reticulated: the liver at the heart of atherosclerosis  Academic Article
• Lysophosphatidylcholine is a Major Component of Platelet Microvesicles Promoting Platelet Activation and Reporting Atherosclerotic Plaque Instability  Academic Article
• Mcl-1 and Bcl-xL coordinately regulate megakaryocyte survival  Academic Article
• Measuring oxidative burden and predicting pharmacological response in coronary artery disease patients with a novel direct activator of haem-free/oxidised sGC  Academic Article
• Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets  Academic Article
• Microparticles: major transport vehicles for distinct microRNAs in circulation  Academic Article
• Molecular Imaging of Activated Platelets Allows the Detection of Pulmonary Embolism with Magnetic Resonance Imaging  Academic Article
• Molecular Magnetic Resonance Imaging Allows the Detection of Activated Platelets in a New Mouse Model of Coronary Artery Thrombosis  Academic Article
• Molecular imaging of activated platelets via antibody-targeted ultra-small iron oxide nanoparticles displaying unique dual MRI contrast  Academic Article
• Monomeric C-Reactive Protein Generation on Activated Platelets: The Missing Link Between Inflammation and Atherothrombotic Risk  Academic Article
• Multifunctional Thrombin-Activatable Polymer Capsules for Specific Targeting to Activated Platelets  Academic Article
• Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia  Academic Article
• Nerve Growth Factor Inhibits Metalloproteinase-Disintegrins and Blocks Ectodomain Shedding of Platelet Glycoprotein VI  Academic Article
• Neutrophil-derived S100 calcium-binding proteins A8/A9 promote reticulated thrombocytosis and atherogenesis in diabetes  Academic Article
• Novel Role for the AnxA1-Fpr2/ALX signaling axis as a key regulator of platelet function to promote resolution of inflammation  Academic Article
• Novel Thrombolytic Drug Based on Thrombin Cleavable Microplasminogen Coupled to a Single‐Chain Antibody Specific for Activated GPIIb/IIIa  Academic Article
• PDE2 inhibition by the PI3 kinase inhibitor LY294002 and analogues  Academic Article
• PI 3-kinase p110β: a new target for antithrombotic therapy  Academic Article
• Pharmacological inhibition of LIM kinase pathway impairs platelets functionality and facilitates thrombolysis  Academic Article
• Pharmacotherapy in cardiovascular diseases and vascular interventions  Academic Article
• Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators  Academic Article
• Physiological restraint of Bak by Bcl-x(L) is essential for cell survival  Academic Article
• Placental and blood element neurotransmitter receptor regulation in humans: potential models for studying neurochemical mechanisms underlying behavioral teratology  Academic Article
• Platelet 5-HT2 serotonin receptor binding sites in autistic children and their first-degree relatives  Academic Article
• Platelet alpha2-adrenergic receptor binding sites in major depressive disorder and borderline personality disorder  Academic Article
• Platelet growth factors: potential impact on transfusion medicine  Academic Article
• Platelet lipidomics and function: Joining the dots  Comment
• Platelet lipidomics: a window of opportunity to assess cardiovascular risk?  Editorial Article
• Platelet receptors as therapeutic targets: Past, present and future  Academic Article
• Platelet serotonin measures in adolescents with conduct disorder  Academic Article
• Platelet-targeted delivery of peripheral blood mononuclear cells to the ischemic heart restores cardiac function after ischemia-reperfusion injury  Academic Article
• Platelet-targeted dual pathway antithrombotic inhibits thrombosis with preserved hemostasis  Academic Article
• Platelets in cardiac ischaemia/reperfusion injury: a promising therapeutic target  Academic Article
• Platelet–Leukocyte–Endothelial Cell Interactions after Middle Cerebral Artery Occlusion and Reperfusion  Academic Article
• Polyphosphate is a novel cofactor for regulation of complement by a serpin, C1 inhibitor  Academic Article
• Preparation of B lymphocyte-specific alloantisera by skin implant immunization of cattle  Academic Article
• Preparation of platelet concentrates  Academic Article
• Preparation of platelet concentrates for research and transfusion purposes  Chapter
• Programmed Anuclear Cell Death Delimits Platelet Life Span  Academic Article
• Progress in bio-manufacture of platelets for transfusion  Academic Article
• Randomized double-blind placebo-controlled crossover study to determine the effects of esomeprazole on inhibition of platelet function by clopidogrel  Academic Article
• Randomized, blinded, placebo-controlled phase I trial of pegylated recombinant human megakaryocyte growth and development factor with filgrastim after dose-intensive chemotherapy in patients with advanced cancer  Academic Article
• Reversibility versus Persistence of GPIIb/IIIa Blocker-Induced Conformational Change of GPIIb/IIIa (αIIbβ3, CD41/CD61)  Academic Article
• Roles of Mac-1 and glycoprotein IIb/IIIa integrins in leukocyte–platelet aggregate formation: Stabilization by Mac-1 and inhibition by GpIIb/IIIa blockers  Academic Article
• Selective inhibition of the platelet phosphoinositide 3-kinase p110β as promising new strategy for platelet protection during extracorporeal circulation  Academic Article
• Shared roles for Scl and Lyl1 in murine platelet production and function  Academic Article
• Short-acting P 2 Y 12 blockade to reduce platelet dysfunction and coagulopathy during experimental extracorporeal circulation and hypothermia  Academic Article
• Single-Chain Antibodies as New Antithrombotic Drugs  Academic Article
• Single-Chain antibody conjugated to a cage amine chelator and labeled with positron-emitting copper-64 for diagnostic imaging of activated platelets  Academic Article
• Snake venom metalloproteinases, crotarhagin and alborhagin, induce ectodomain shedding of the platelet collagen receptor, glycoprotein VI  Academic Article
• Staphylococcal SSL5-induced platelet microparticles provoke proinflammatory responses via the CD40/TRAF6/NF kappa B signalling pathway in monocytes  Academic Article
• Synthesis, DNA-PK inhibition, anti-platelet activity studies of 2-(N-substituted-3-aminopyridine)-substituted-1,3-benzoxazines and DNA-PK and PI3K inhibition, homology modelling studies of 2-morpholino-(7,8-di and 8-substituted)-1,3-benzoxazines  Academic Article
• Synthesis, structure elucidation, DNA-PK, PI3K, anti-platelet and anti-bacteria activity of linear 5, 6, and 10-substituted-2-morpholino-chromen-oxazine-dione and angular 3, 4, 6-substituted-8-morpholino-chromen-oxazine-2,10-dione  Academic Article
• Targeted Antithrombotic Protein Micelles  Academic Article
• Targeting CD39 Toward Activated Platelets Reduces Systemic Inflammation and Improves Survival in Sepsis  Academic Article
• Targeting Ligand-Induced Binding Sites on GPIIb/IIIa via Single-Chain Antibody Allows Effective Anticoagulation Without Bleeding Time Prolongation  Academic Article
• Targeting activated platelets: A unique and potentially universal approach for cancer imaging  Academic Article
• Targeting the Platelet Integrin GPIIb/IIIa  Academic Article
• The Effect of Intravenously Administered Magnesium on Platelet Function in Patients After Cardiac Surgery  Academic Article
• The alpha 2-adrenergic receptor: multiple affinity states and regulation of a receptor inversely coupled to adenylate cyclase.  Academic Article
• The anti-platelet effects of apocynin in mice are not mediated by inhibition of NADPH oxidase activity  Academic Article
• The class II PI 3-kinase, PI3KC2α, links platelet internal membrane structure to shear-dependent adhesive function  Academic Article
• The nitric oxide redox sibling nitroxyl partially circumvents impairment of platelet nitric oxide responsiveness  Academic Article
• The pulmonary microvasculature entraps induced vascular progenitor cells (iVPCs) systemically delivered after cardiac ischemia-reperfusion injury: Indication for preservation of heart function via paracrine effects beyond engraftment  Academic Article
• Therapeutic integrin inhibition: Allosteric and activation-specific inhibition strategies may surpass the initial ligand-mimetic strategies  Academic Article
• Therapeutische Inhibition von Thrombozyten im akuten Koronarsyndrom und bei Koronarintervention: Mechanismen und klinische Ergebnisse  Academic Article
• Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene  Academic Article
• Thrombus-Targeted Theranostic Microbubbles: A New Technology towards Concurrent Rapid Ultrasound Diagnosis and Bleeding-free Fibrinolytic Treatment of Thrombosis  Academic Article
• Towards effective and safe thrombolysis and thromboprophylaxis  Academic Article
• Visualization of Activated Platelets by Targeted Magnetic Resonance Imaging Utilizing Conformation-Specific Antibodies against Glycoprotein IIb/IIIa  Academic Article
• What do we mean by the term "inflammation"? A contemporary basic science update for sports medicine  Academic Article