subject area of

• A Long, Naturally Presented Immunodominant Epitope from NY-ESO-1 Tumor Antigen: Implications for Cancer Vaccine Design  Academic Article
• A Myc-dependent division timer complements a cell-death timer to regulate T cell and B cell responses  Academic Article
• A Novel HLA-B18 Restricted CD8+ T Cell Epitope Is Efficiently Cross-Presented by Dendritic Cells from Soluble Tumor Antigen  Academic Article
• A conserved energetic footprint underpins recognition of Human Leukocyte Antigen-E by two distinct αβ T cell receptors  Academic Article
• A molecular threshold for effector CD8(+) T cell differentiation controlled by transcription factors Blimp-1 and T-bet  Academic Article
• A robust human T-cell culture method suitable for monitoring CD8+ and CD4+ T-cell responses from cancer clinical trial samples  Academic Article
• A virus-specific CD8+ T cell immunodominance hierarchy determined by antigen dose and precursor frequencies  Academic Article
• Activin-A: a novel dendritic cell–derived cytokine that potently attenuates CD40 ligand–specific cytokine and chemokine production  Academic Article
• Addition of a Prominent Epitope Affects Influenza A Virus-Specific CD8+T Cell Immunodominance Hierarchies When Antigen Is Limiting  Academic Article
• An optimized method for establishing high purity murine CD8+ T cell cultures  Academic Article
• Antigen affinity, costimulation, and cytokine inputs sum linearly to amplify T cell expansion  Academic Article
• Assessment of metabolic and mitochondrial dynamics in CD4+ and CD8+ T cells in virologically suppressed HIV-positive individuals on combination antiretroviral therapy  Academic Article
• Asymmetric Cell Division of T Cells upon Antigen Presentation Uses Multiple Conserved Mechanisms  Academic Article
• Blood Dendritic Cells Generated With Flt3 Ligand and CD40 Ligand Prime CD8+ T Cells Efficiently in Cancer Patients  Academic Article
• Both IFN-γ and IL-17 are required for the development of severe autoimmune gastritis  Academic Article
• Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans  Academic Article
• Burn Injury Leads to Increased Long-Term Susceptibility to Respiratory Infection in both Mouse Models and Population Studies  Academic Article
• CAR-T Cells Inflict Sequential Killing of Multiple Tumor Target Cells  Academic Article
• CD4 ⁺ T-cell deficiency in HIV patients responding to antiretroviral therapy is associated with increased expression of interferon-stimulated genes in CD4 ⁺ T cells  Academic Article
• CD45+CD33lowCD11bdim myeloid-derived suppressor cells suppress CD8+ T cell activity via the IL-6/IL-8-arginase I axis in human gastric cancer  Academic Article
• CD8+ T Cells that Produce Interlukin-17 Regulate Myeloid-derived Suppressor Cells and are Associated with Survival Time of Patients with Gastric Cancer  Academic Article
• CD8+ T cell responses against a dominant cryptic HLA-A2 epitope after NY-ESO-1 peptide immunization of cancer patients  Academic Article
• Cancer/testis antigens can be immunological targets in clonogenic CD133+ melanoma cells  Academic Article
• Cells adapted to the proteasome inhibitor 4-hydroxy- 5-iodo-3-nitrophenylacetyl-Leu-Leu-leucinal-vinyl sulfone require enzymatically active proteasomes for continued survival  Academic Article
• Challenging immunodominance of influenza-specific CD8+ T cell responses restricted by the risk-associated HLA-A*68:01 allomorph  Academic Article
• Characterization of antigen-specific CD8+ T lymphocyte responses in skin and peripheral blood following intradermal peptide vaccination  Academic Article
• Chemically attenuated Plasmodium sporozoites induce specific immune responses, sterile immunity and cross-protection against heterologous challenge  Academic Article
• Cognate antigen engagement on parenchymal cells stimulates CD8+ T cell proliferation in situ  Academic Article
• Combination anti–CTLA-4 plus anti–PD-1 checkpoint blockade utilizes cellular mechanisms partially distinct from monotherapies  Academic Article
• Combining MHC tetramer and intracellular cytokine staining for CD8+ T cells to reveal antigenic epitopes naturally presented on tumor cells  Academic Article
• Comparative analysis reveals a role for TGF-β in shaping the residency-related transcriptional signature in tissue-resident memory CD8+ T cells  Academic Article
• Compartment resolved reference proteome map from highly purified naive, activated, effector, and memory CD8(+) murine immune cells  Academic Article
• Compartmentalized MHC class I antigen processing enhances immunosurveillance by circumventing the law of mass action  Academic Article
• Control of lymphocyte fate, infection, and tumor immunity by TCF-1  Academic Article
• Cross-priming of CD8+ T cells by viral and tumor antigens is a robust phenomenon  Academic Article
• Cutting Edge: Recombinant Adenoviruses Induce CD8 T Cell Responses to an Inserted Protein Whose Expression Is Limited to Nonimmune Cells  Academic Article
• Differential Regulation of Simultaneous Antitumor and Alloreactive CD8+ T-Cell Responses in the Same Host by Rapamycin  Academic Article
• Differential expansion of T central memory precursor and effector subsets is regulated by division speed  Academic Article
• Direct antigen presentation by DC shapes the functional CD8+T-cell repertoire against the nuclear self-antigen La-SSB  Academic Article
• Discordant Regulation of Granzyme H and Granzyme B Expression in Human Lymphocytes  Academic Article
• Dissecting the Multifactorial Causes of Immunodominance in Class I–Restricted T Cell Responses to Viruses  Academic Article
• Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade  Academic Article
• Dual-specific Chimeric Antigen Receptor T Cells and an Indirect Vaccine Eradicate a Variety of Large Solid Tumors in an Immunocompetent, Self-antigen Setting  Academic Article
• Dynamic quantification of MHC class I–peptide presentation to CD8+ T cells via intracellular cytokine staining  Academic Article
• Early precursor T cells establish and propagate T cell exhaustion in chronic infection  Academic Article
• Efficiency of T‐cell costimulation by CD80 and CD86 cross‐linking correlates with calcium entry  Academic Article
• Engagement of the Signaling Lymphocytic Activation Molecule (SLAM) on Activated T Cells Results in IL-2-Independent, Cyclosporin A-Sensitive T Cell Proliferation and IFN-γ Production  Academic Article
• Evaluation of cellular immune responses in cancer vaccine recipients: lessons from NY-ESO-1  Academic Article
• Extrinsically derived TNF is primarily responsible for limiting antiviral CD8+ T cell response magnitude  Academic Article
• FACS isolation of low percentage human antigen-specific CD8+ T cells based on activation-induced CD3 and CD8 downregulation  Academic Article
• Flt3 ligand expands CD4+FoxP3+regulatory T cells in human subjects  Academic Article
• Generic construction of single component particles that elicit humoural and cellular immune responses without the need for adjuvants  Academic Article
• Genome-Wide Identification of Long Noncoding RNAs in CD8+T Cells  Academic Article
• Gp130-dependent astrocytic survival is critical for the control of autoimmune central nervous system inflammation  Academic Article
• HER2-Specific T-Cell Immune Responses in Patients Vaccinated with Truncated HER2 Protein Complexed with Nanogels of Cholesteryl Pullulan  Academic Article
• Heat-Aggregated Noninfectious Influenza Virus Induces a More Balanced CD8+-T-Lymphocyte Immunodominance Hierarchy Than Infectious Virus  Academic Article
• Helicobacter pylori–induced matrix metallopeptidase-10 promotes gastric bacterial colonization and gastritis  Academic Article
• Immunodominance Hierarchies and Gender Bias in Direct TCD8-Cell Alloreactivity  Academic Article
• Immunodominance and Immunodomination: Critical Factors in Developing Effective CD8+ T‐Cell–Based Cancer Vaccines  Book
• Immunodominant CD4+ responses identified in a patient vaccinated with full-length NY-ESO-1 formulated with ISCOMATRIX adjuvant  Academic Article
• Immunoproteasome Subunit Deficiencies Impact Differentially on Two Immunodominant Influenza Virus-Specific CD8+ T Cell Responses  Academic Article
• Immunoproteasomes Shape Immunodominance Hierarchies of Antiviral Cd8+ T Cells at the Levels of T Cell Repertoire and Presentation of Viral Antigens  Academic Article
• Inactivated Influenza Vaccine That Provides Rapid, Innate-Immune-System-Mediated Protection and Subsequent Long-Term Adaptive Immunity  Academic Article
• Increased tumor-infiltrating CD45RA−CCR7− regulatory T-cell subset with immunosuppressive properties foster gastric cancer progress  Academic Article
• Increasing Viral Dose Causes a Reversal in CD8+T Cell Immunodominance during Primary Influenza Infection due to Differences in Antigen Presentation, T Cell Avidity, and Precursor Numbers  Academic Article
• Influenza A Infection Enhances Cross-Priming of CD8+T Cells to Cell-Associated Antigens in a TLR7- and Type I IFN-Dependent Fashion  Academic Article
• Influenza A virus infection induces viral and cellular defective ribosomal products encoded by alternative reading frames  Academic Article
• Inhibitory Effects of Cytomegalovirus Proteins US2 and US11 Point to Contributions from Direct Priming and Cross-Priming in Induction of Vaccinia Virus-Specific CD8+ T Cells  Academic Article
• Lentivector immunization induces tumor antigen‐specific B and T cell responsesin vivo  Academic Article
• Lethal giant larvae-1 deficiency enhances the CD8⁺ effector T-cell response to antigen challenge in vivo  Academic Article
• Location rather than CD62L phenotype is critical in the early establishment of influenza-specific CD8+ T cell memory  Academic Article
• Mice Deficient in Perforin, CD4+ T Cells, or CD28-Mediated Signaling Maintain the Typical Immunodominance Hierarchies of CD8+ T-Cell Responses to Influenza Virus  Academic Article
• Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8+ T Cells  Academic Article
• Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis  Academic Article
• Mixed Proteasomes Function To Increase Viral Peptide Diversity and Broaden Antiviral CD8+ T Cell Responses  Academic Article
• Multiplex immunohistochemistry accurately defines the immune context of metastatic melanoma  Academic Article
• Multiplexed Division Tracking Dyes for Proliferation-Based Clonal Lineage Tracing  Academic Article
• NLRC4 inflammasomes in dendritic cells regulate noncognate effector function by memory CD8+ T cells  Academic Article
• NY-ESO-1 Protein Formulated in ISCOMATRIX Adjuvant Is a Potent Anticancer Vaccine Inducing Both Humoral and CD8+ T-Cell-Mediated Immunity and Protection against NY-ESO-1+ Tumors  Academic Article
• NY-ESO-1 specific antibody and cellular responses in melanoma patients primed with NY-ESO-1 protein in ISCOMATRIX and boosted with recombinant NY-ESO-1 fowlpox virus  Academic Article
• Neoadjuvant Interferons: Critical for Effective PD-1–Based Immunotherapy in TNBC  Academic Article
• Nucleoprotein of influenza A virus is a major target of immunodominant CD8 + T‐cell responses  Academic Article
• Optimal conditions required for influenza A infection‐enhanced cross‐priming of CD8 + T cells specific to cell‐associated antigens  Academic Article
• Perpetual complexity: predicting human CD8 + T-cell responses to pathogenic peptides  Academic Article
• Recombinant NY-ESO-1 protein with ISCOMATRIX adjuvant induces broad integrated antibody and CD4+ and CD8+ T cell responses in humans  Academic Article
• Recovery from severe H7N9 disease is associated with diverse response mechanisms dominated by CD8+ T cells  Academic Article
• Regulation of asymmetric cell division and polarity by Scribble is not required for humoral immunity  Academic Article
• Repurposed JAK1/JAK2 Inhibitor Reverses Established Autoimmune Insulitis in NOD Mice  Academic Article
• Resident CD8+ and Migratory CD103+ Dendritic Cells Control CD8 T Cell Immunity during Acute Influenza Infection  Academic Article
• Reversal in the Immunodominance Hierarchy in Secondary CD8+ T Cell Responses to Influenza A Virus: Roles for Cross-Presentation and Lysis-Independent Immunodomination  Academic Article
• Serglycin determines secretory granule repertoire and regulates natural killer cell and cytotoxic T lymphocyte cytotoxicity  Academic Article
• Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape  Academic Article
• Standard and immunoproteasomes show similar peptide degradation specificities  Editorial Article
• Stochastic measurement models for quantifying lymphocyte responses using flow cytometry  Academic Article
• Striking Immunodominance Hierarchy of Naturally Occurring CD8+ and CD4+ T Cell Responses to Tumor Antigen NY-ESO-1  Academic Article
• Stroke and T-Cells  Academic Article
• Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma  Academic Article
• Suboptimal SARS-CoV-2−specific CD8+ T cell response associated with the prominent HLA-A*02:01 phenotype  Academic Article
• Suppressor of cytokine signaling 3 regulates CD8 T-cell proliferation by inhibition of interleukins 6 and 27  Academic Article
• Systematic identification of immunodominant CD8+ T-cell responses to influenza A virus in HLA-A2 individuals  Academic Article
• T cells recognizing a 11mer influenza peptide complexed to H-2D(b) show promiscuity for peptide length  Academic Article
• T-box Transcription Factors Combine with the Cytokines TGF-beta and IL-15 to Control Tissue-Resident Memory T Cell Fate  Academic Article
• T-cell stimuli independently sum to regulate an inherited clonal division fate  Academic Article
• TCF-1 limits the formation of Tc17 cells via repression of the MAF-RORγt axis  Academic Article
• Targeting the intracellular WT1 oncogene product with a therapeutic human antibody  Academic Article
• The Early Expression of Glycoprotein B from Herpes Simplex Virus Can Be Detected by Antigen-Specific CD8+ T Cells  Academic Article
• The Exception that Reinforces the Rule: Crosspriming by Cytosolic Peptides that Escape Degradation  Academic Article
• The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin  Academic Article
• The impact of 6-month training preparation for an Ironman triathlon on the proportions of naïve, memory and senescent T cells in resting blood  Academic Article
• The impact of imiquimod, a Toll-like receptor-7 ligand (TLR7L), on the immunogenicity of melanoma peptide vaccination with adjuvant Flt3 ligand.  Academic Article
• The transcription factor IRF4 is essential for TCR affinity–mediated metabolic programming and clonal expansion of T cells  Academic Article
• Transcription Factor IRF4 Promotes CD8+ T Cell Exhaustion and Limits the Development of Memory-like T Cells during Chronic Infection  Academic Article
• Tumor antigen processing and presentation depend critically on dendritic cell type and the mode of antigen delivery  Academic Article
• Tumor immune evasion arises through loss of TNF sensitivity  Academic Article
• Tumor-Specific T-cell Help Is Associated with Improved Survival in Melanoma  Editorial Article
• Visualizing CTL activity for different CD8+ effector T cells supports the idea that lower TCR/epitope avidity may be advantageous for target cell killing  Academic Article