subject area of

• A Direct Phenotypic Comparison of siRNA Pools and Multiple Individual Duplexes in a Functional Assay  Academic Article
• A Myc-dependent division timer complements a cell-death timer to regulate T cell and B cell responses  Academic Article
• A Structural Viral Mimic of Prosurvival Bcl-2: A Pivotal Role for Sequestering Proapoptotic Bax and Bak  Academic Article
• A model of immune regulation as a consequence of randomized lymphocyte division and death times  Academic Article
• A single-cell pedigree analysis of alternative stochastic lymphocyte fates  Academic Article
• A truncated fragment of Src protein kinase generated by calpain-mediated cleavage is a mediator of neuronal death in excitotoxicity  Academic Article
• A type III effector antagonizes death receptor signalling during bacterial gut infection  Academic Article
• Activated microglia decrease histone acetylation and Nrf2-inducible anti-oxidant defence in astrocytes: Restoring effects of inhibitors of HDACs, p38 MAPK and GSK3β  Academic Article
• Activation-Induced B Cell Fates Are Selected by Intracellular Stochastic Competition  Academic Article
• An appointment with death,: 2013 Cold Spring Harbor Asia meeting 'Mechanisms and Functions of Non-Apoptotic Cell Death'  Conference Paper
• Another Facet of Ubiquitylation: Death  Academic Article
• Asymmetric cell division during T cell development controls downstream fate  Academic Article
• B-cell-specific depletion of tumour necrosis factor alpha inhibits atherosclerosis development and plaque vulnerability to rupture by reducing cell death and inflammation  Academic Article
• Bcl -2 prevents death of factor-deprived cells but fails to prevent apoptosis in targets of cell mediated killing  Academic Article
• Bcl-2, Bcl-x L, and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells  Academic Article
• Bone morphogenetic protein-7 induces telomerase inhibition, telomere shortening, breast cancer cell senescence, and death via Smad3 (FASEB Journal (2009) DOI: 10.1096/fj.08-119529)  Academic Article
• CLL cells are resistant to smac mimetics because of an inability to form a ripoptosome complex.  Academic Article
• Cell Death in Development  Academic Article
• Cell death is not essential for caspase-1-mediated interleukin-1β activation and secretion  Academic Article
• Cell death provoked by loss of interleukin-3 signaling is independent of Bad, Bim, and PI3 kinase, but depends in part on Puma  Academic Article
• Cell death regulation by the mammalian IAP antagonist Diablo/Smac  Academic Article
• Cellular Mechanisms of Risk and Transformation  Conference Paper
• Cellular and molecular mechanisms of mitochondrial function  Academic Article
• Chimeric antigen receptor T cells form nonclassical and potent immune synapses driving rapid cytotoxicity  Academic Article
• Circulating non-coding RNAs as biomarkers of beta cell death in diabetes.  Academic Article
• Classification of cell death: recommendations of the Nomenclature Committee on Cell Death  Academic Article
• Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis  Academic Article
• Cooperative and independent roles of the Drp1 adaptors Mff, MiD49 and MiD51 in mitochondrial fission  Academic Article
• Cycloheximide can induce Bax/Bak dependent myeloid cell death independently of multiple BH3-only proteins  Academic Article
• Cytokine receptor signaling activates an IKK-dependent phosphorylation of PUMA to prevent cell death  Academic Article
• Cytotoxic T lymphocyte–induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis  Academic Article
• Death in the snow: report on Keystone Conference on ‘Apoptosis and Programmed Cell Death’ at Breckenridge, CO, April 6–11th 1999  Conference Paper
• Dysregulating ClpP: From Antibiotics to Anticancer?  Review
• EGL-1 BH3 mutants reveal the importance of protein levels and target affinity for cell-killing potency  Academic Article
• Early work on the function of Bcl-2, an interview with David Vaux  Academic Article
• Effect of a Selective Mas Receptor Agonist in Cerebral Ischemia In Vitro and In Vivo  Academic Article
• Endogenous bcl-2 is not required for the development of E -myc induced B-cell lymphoma  Academic Article
• EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation  Academic Article
• Estimating Lymphocyte Division and Death Rates from CFSE Data  Academic Article
• Evidence that collaboration between HIF-1α and Notch-1 promotes neuronal cell death in ischemic stroke  Academic Article
• Evidence that neuronal Notch-1 promotes JNK/c-Jun activation and cell death following ischemic stress  Academic Article
• Evidence that γ-secretase-mediated notch signaling induces neuronal cell death via the nuclear factor-κB-Bcl-2-interacting mediator of cell death pathway in ischemic stroke  Academic Article
• Extracellular wildtype and mutant SOD1 induces ER–Golgi pathology characteristic of amyotrophic lateral sclerosis in neuronal cells  Academic Article
• Fight or flight: Regulation of emergency hematopoiesis by pyroptosis and necroptosis  Academic Article
• Gefitinib-Induced Killing of NSCLC Cell Lines Expressing Mutant EGFR Requires BIM and Can Be Enhanced by BH3 Mimetics  Academic Article
• Gold and Silver Nanoparticles Biomimetically Synthesized Using Date Palm Pollen Extract-Induce Apoptosis and Regulate p53 and Bcl-2 Expression in Human Breast Adenocarcinoma Cells  Academic Article
• Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes  Academic Article
• HMG-CoA reductase promotes protein prenylation and therefore is indispensible for T-cell survival  Academic Article
• HOIP deficiency causes embryonic lethality by aberrant TNFR1-mediated endothelial cell death  Academic Article
• HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death  Academic Article
• Highly Selective and Prolonged Depletion of Mitochondrial Glutathione in Astrocytes Markedly Increases Sensitivity to Peroxynitrite  Academic Article
• Histidine-rich glycoprotein: the Swiss Army knife of mammalian plasma  Academic Article
• Host Responses to Group A Streptococcus: Cell Death and Inflammation  Academic Article
• Hoxb8 regulates expression of microRNAs to control cell death and differentiation  Academic Article
• IAPs and cell death  Chapter
• In TNF-stimulated Cells, RIPK1 Promotes Cell Survival by Stabilizing TRAF2 and cIAP1, which Limits Induction of Non-canonical NF-κB and Activation of Caspase-8  Academic Article
• In mouse embryonic fibroblasts, neither caspase-8 nor cellular FLICE-inhibitory protein (FLIP) is necessary for TNF to activate NF-κB, but caspase-8 is required for TNF to cause cell death and induction of FLIP by NF-κB is required to prevent it  Academic Article
• In the midst of life—cell death: what is it, what is it good for, and how to study it  Academic Article
• Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin  Academic Article
• Inhibition of interleukin 1 -converting enzyme-mediated apoptosis of mammalian cells by baculovirus IAP  Conference Paper
• Inhibitor of Apoptosis Proteins (IAPs) Limit RIPK1-Mediated Skin Inflammation  Academic Article
• Inhibitor of apoptosis protein-1 regulates tumor necrosis factor-mediated destruction of intestinal epithelial cells  Academic Article
• Intravenous immunoglobulin protects neurons against amyloid beta-peptide toxicity and ischemic stroke by attenuating multiple cell death pathways  Academic Article
• Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke  Academic Article
• LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis  Academic Article
• LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L  Academic Article
• MCL-1 inhibition provides a new way to suppress breast cancer metastasis and increase sensitivity to dasatinib  Academic Article
• Mammary Gland Remodeling Depends on gp130 Signaling through Stat3 and MAPK  Academic Article
• Mesenchymal stromal cell turnover in the normal adult lung revisited  Academic Article
• Mitochondrial glutathione protects against cell death induced by oxidative and nitrative stress in astrocytes  Academic Article
• Molecular determinants of Smac mimetic induced degradation of cIAP1 and cIAP2  Academic Article
• Monitoring the progression of cell death and the disassembly of dying cells by flow cytometry  Academic Article
• More than cell death: Caspases and caspase inhibitors on the move  Academic Article
• Multifaceted deaths orchestrated by mitochondria in neurones  Academic Article
• Neither macromolecular synthesis nor myc is required for cell death via the mechanism that can be controlled by Bcl-2.  Academic Article
• New Perspectives in TNF-R1-Induced NF-kappa B Signaling  Conference Paper
• Notch signaling and neuronal death in stroke  Academic Article
• Pathogenesis of acute stroke and the role of inflammasomes  Academic Article
• Phosphoinositide-mediated oligomerization of a defensin induces cell lysis  Academic Article
• Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2  Academic Article
• Protoplast cell death assay to study magnaporthe oryzae AVR gene function in rice  Academic Article
• RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis  Academic Article
• Recent advances in understanding inhibitor of apoptosis proteins [version 1; referees: 2 approved]  Academic Article
• Repeated transient sulforaphane stimulation in astrocytes leads to prolonged Nrf2-mediated gene expression and protection from superoxide-induced damage  Academic Article
• Signals Regulating Neurogenesis in the Adult Olfactory Bulb  Conference Paper
• Stochastic Model of T Cell Proliferation: A Calculus Revealing IL-2 Regulation of Precursor Frequencies, Cell Cycle Time, and Survival  Academic Article
• TCR Affinity Promotes CD8+ T Cell Expansion by Regulating Survival  Academic Article
• TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice  Academic Article
• TWEAK shall inherit the earth  Academic Article
• TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα  Academic Article
• Targeting of Fn14 Prevents Cancer-Induced Cachexia and Prolongs Survival  Academic Article
• The Bcl-2 family in autoimmune and degenerative disorders  Academic Article
• The Carboxyl-Terminal Domain of Inducible Hsp70 Protects from Ischemic Injury in vivo and in vitro  Academic Article
• The MYB80 Transcription Factor Is Required for Pollen Development and the Regulation of Tapetal Programmed Cell Death in Arabidopsis thaliana  Academic Article
• The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis  Academic Article
• The Role of Intracellularly Released Formaldehyde and Butyric Acid in the Anticancer Activity of Acyloxyalkyl Esters  Academic Article
• The importance of being chaperoned: HSP90 and necroptosis  Editorial Article
• The lethal giant larvae tumour suppressor mutation requires dMyc oncoprotein to promote clonal malignancy  Academic Article
• The medical significance of physiological cell death  Academic Article
• The metabolism of 14C-glucose by neurons and astrocytes in brain subregions following focal cerebral ischemia in rats  Academic Article
• The mitochondrial outer membrane AAA ATPase AtOM66 affects cell death and pathogen resistance in Arabidopsis thaliana  Academic Article
• The molecular and cellular basis of pathogenesis in melioidosis: how does Burkholderia pseudomallei cause disease?  Academic Article
• The proliferative response of CD4 T cells to steady-state CD8+ dendritic cells is restricted by post-activation death  Academic Article
• Thirty years of BCL-2: translating cell death discoveries into novel cancer therapies  Academic Article
• Toward an understanding of the molecular mechanisms of physiological cell death.  Academic Article
• Ubiquitylation and Cancer Development  Academic Article
• XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation  Academic Article
• ‘Did He Who Made the Lamb Make Thee?’ New Developments in Treating the ‘Fearful Symmetry’ of Acute Myeloid Leukemia  Academic Article