Cell Transformation, Neoplastic
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A Raf-1 Mutant That Dissociates MEK/Extracellular Signal-Regulated Kinase Activation from Malignant Transformation and Differentiation but Not Proliferation Academic Article
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A Review: Biological and Clinical Aspects of Pyrimidine Metabolism Academic Article
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A Tumor Cell-Specific Nuclear Targeting Signal within Chicken Anemia Virus VP3/Apoptin Academic Article
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A comparison between Ki-67 antibody reactivity and other pathological variables in breast carcinoma Academic Article
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A hypermorphic epithelial beta-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations Academic Article
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Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers Academic Article
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Analysis of Ras-induced oncogenic transformation of NIH-3T3 cells using differential-display 2-DE proteomics Academic Article
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Antiviral and Antiproliferative Activities of Interferon-α1: The Role of Cysteine Residues Academic Article
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Autophagy suppresses Ras-driven epithelial tumourigenesis by limiting the accumulation of reactive oxygen species Academic Article
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Bcl-2 family proteins: The sentinels of the mitochondrial apoptosis pathway Academic Article
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Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells Academic Article
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Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic Academic Article
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Cartilage proteoglycan degradation by a mouse transformed macrophage cell line is mediated by macrophage metalloelastase Academic Article
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Cellular Mechanisms of Risk and Transformation Conference Paper
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Colorectal cancer mouse models: integrating inflammation and the stroma Academic Article
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Control of glioblastoma tumorigenesis by feed-forward cytokine signaling Academic Article
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Cytosine Arabinoside Influx and Nucleoside Transport Sites in Acute Leukemia Academic Article
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Differential effects of DNA synthesis inhibitors on DNA methylation in normal and transformed cells Academic Article
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Differential role of MyD88 and Mal/TIRAP in TLR2-mediated gastric tumourigenesis Academic Article
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Drosophila models of cell polarity and cell competition in tumourigenesis Chapter
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ELF3, ELF5, EHF and SPDEF transcription factors in tissue homeostasis and cancer Academic Article
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Early work on the function of Bcl-2, an interview with David Vaux Academic Article
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Effect of thymidine analogs on tyrosinase activity and mRNA accumulation in mouse melanoma cells Academic Article
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Effects of Sodium Butyrate on the Synthesis and Methylation of DNA in Normal Cells and Their Transformed Counterparts Academic Article
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Emerging roles of exosomes during epithelial-mesenchymal transition and cancer progression Academic Article
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Enforced expression of the homeobox gene Mixl1 impairs hematopoietic differentiation and results in acute myeloid leukemia Academic Article
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Environment-gene interactions in intestinal cancer Conference Paper
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Eph/Ephrin Signalling and Function in Oncogenesis: Lessons from Embryonic Development Academic Article
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Epithelial gp130/Stat3 functions: An intestinal signaling node in health and disease Academic Article
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Extracellular Remodelling During Oncogenic Ras-Induced Epithelial-Mesenchymal Transition Facilitates MDCK Cell Migration Academic Article
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Genomic Classification of Serous Ovarian Cancer with Adjacent Borderline Differentiates RAS Pathway and TP53-Mutant Tumors and Identifies NRAS as an Oncogenic Driver Academic Article
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HOXB7, a Homeodomain Protein, Is Overexpressed in Breast Cancer and Confers Epithelial-Mesenchymal Transition Academic Article
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High-Contrast PET of Melanoma Using 18F-MEL050, a Selective Probe for Melanin with Predominantly Renal Clearance Academic Article
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Human ERG is a proto-oncogene with mitogenic and transforming activity Academic Article
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Immuno-PET Quantitation of de2-7 Epidermal Growth Factor Receptor Expression in Glioma Using 124I-IMP-R4-Labeled Antibody ch806 Academic Article
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In Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1-Rok-Myosin-II and JNK signalling Academic Article
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Inflammasome adaptor ASC suppresses apoptosis of gastric cancer cells by an IL18-mediated inflammation-independent mechanism Academic Article
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Influence of HPV16 E2 and its localisation on the expression of matrix metalloproteinase-9 Academic Article
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Interleukin 33 Signaling Restrains Sporadic Colon Cancer in an Interferon-γ–Dependent Manner Academic Article
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Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically Academic Article
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Is CD1a involved in antitumour immune responses during carcinogenesis? Academic Article
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Kaiso-Deficient Mice Show Resistance to Intestinal Cancer Academic Article
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Loss of NF-κB1 Causes Gastric Cancer with Aberrant Inflammation and Expression of Immune Checkpoint Regulators in a STAT-1-Dependent Manner Academic Article
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Loss of Prkar1a leads to Bcl-2 family protein induction and cachexia in mice Academic Article
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Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling Academic Article
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Loss of the EPH receptor B6 contributes to colorectal cancer metastasis Academic Article
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Malignant transformation of a growth factor-dependent myeloid cell line by Abelson virus without evidence of an autocrine mechanism Academic Article
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Malignant transformation of oral submucous fibrosis: overview of histopathological aspects Academic Article
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Molecular Imaging and Quantitation of EphA2 Expression in Xenograft Models with Zr-89-DS-8895a Academic Article
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Molecular Pathology of Malignant Transformation of Oral Submucous Fibrosis Academic Article
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Molecular pathways: IL11 as a tumor-promoting cytokine-translational implications for cancers Academic Article
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Mutation of NIMA-related kinase 1 (NEK1) leads to chromosome instability Academic Article
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Oncogenic B-Raf mutations Academic Article
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Oncogenic H-Ras Reprograms Madin-Darby Canine Kidney (MDCK) Cell-derived Exosomal Proteins Following Epithelial-Mesenchymal Transition Academic Article
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Oncogenic epithelial cell-derived exosomes containing Rac1 and PAK2 induce angiogenesis in recipient endothelial cells Academic Article
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OncogenicK-RASIs Required to Maintain Changes in Cytoskeletal Organization, Adhesion, and Motility in Colon Cancer Cells Academic Article
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Paneth cell marker expression in intestinal villi and colon crypts characterizes dietary induced risk for mouse sporadic intestinal cancer Academic Article
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Podoplanin is a component of extracellular vesicles that reprograms cell-derived exosomal proteins and modulates lymphatic vessel formation Academic Article
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Preclinical characterization of 18F-D-FPHCys, a new amino acid-based PET tracer Academic Article
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Radiolabelling and evaluation of novel haloethylsulfoxides as PET imaging agents for tumor hypoxia Academic Article
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Regulation of Nuclear Transport: Central Role in Development and Transformation? Academic Article
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Role of Phosphatidylinositol 4,5-Bisphosphate in Ras/Rac-Induced Disruption of the Cortactin-Actomyosin II Complex and Malignant Transformation Academic Article
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SCL, the gene implicated in human T-cell leukaemia, is oncogenic in a murine T-lymphocyte cell line Academic Article
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Scrib heterozygosity predisposes to lung cancer and cooperates with KRas hyperactivation to accelerate lung cancer progression in vivo Academic Article
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Secretome-Based Proteomic Profiling of Ras-Transformed MDCK Cells Reveals Extracellular Modulators of Epithelial-Mesenchymal Transition Academic Article
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T-cell receptor and immunoglobulin genes are rearranged together in Abelson virus-transformed pre-B and pre-T cells. Academic Article
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Targeting EphA3 inhibits cancer growth by disrupting the tumor stromal microenvironment Academic Article
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Targeting of the Tumor Suppressor GRHL3 by a miR-21-Dependent Proto-Oncogenic Network Results in PTEN Loss and Tumorigenesis Academic Article
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The EGFRvIII variant in glioblastoma multiforme Academic Article
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The Phosphoprotein StarD10 Is Overexpressed in Breast Cancer and Cooperates with ErbB Receptors in Cellular Transformation Academic Article
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The Scribble Cell Polarity Module in the Regulation of Cell Signaling in Tissue Development and Tumorigenesis Academic Article
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The Scribble-Dlg-Lgl polarity module in development and cancer: From flies to man Academic Article
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The lethal giant larvae tumour suppressor mutation requires dMyc oncoprotein to promote clonal malignancy Academic Article
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The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy Academic Article
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Therapeutically exploiting STAT3 activity in cancer — using tissue repair as a road map Academic Article
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Towards understanding epithelial–mesenchymal transition: A proteomics perspective Academic Article
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Transformation of Astrocytes in Transgenic Mice Expressing SV40 T Antigen under the Transcriptional Control of the Glial Fibrillary Acidic Protein Promoter Academic Article
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Transformed MDCK cells secrete elevated MMP1 that generates LAMA5 fragments promoting endothelial cell angiogenesis Academic Article
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Transforming growth factor(s) production enables cells to grow in the absence of serum: an autocrine system. Academic Article
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Tumour targeting of Auger emitters using DNA ligands conjugated to octreotate Conference Paper
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scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs Academic Article
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β-Catenin/Tcf-4 Inhibition After Progastrin Targeting Reduces Growth and Drives Differentiation of Intestinal Tumors Academic Article