subject area of

• A Luminogen with Aggregation-Induced Emission Characteristics for Wash-Free Bacterial Imaging, High-Throughput Antibiotics Screening and Bacterial Susceptibility Evaluation  Academic Article
• A novel mouse model of atherosclerotic plaque Instability for drug testing and mechanistic/therapeutic discoveries using gene and microRNA expression profiling  Academic Article
• A screening method for cardiovascular active compounds in marine algae  Academic Article
• Analysis of anti-PDE3 activity of 2-morpholinochromone derivatives reveals multiple mechanisms of anti-platelet activity  Academic Article
• Anticancer prodrugs of butyric acid and formaldehyde protect against doxorubicin-induced cardiotoxicity  Academic Article
• Antimalarial activity of novel 4-cyano-3-methylisoquinoline inhibitors against Plasmodium falciparum: design, synthesis and biological evaluation  Academic Article
• Clinically relevant inflammatory breast cancer patient-derived xenograft–derived ex vivo model for evaluation of tumor-specific therapies  Academic Article
• Defining the target specificity of ABT-737 and synergistic antitumor activities in combination with histone deacetylase inhibitors  Academic Article
• Detection of Inhibitors of Phenotypically Drug-tolerant Mycobacterium tuberculosis Using an In Vitro Bactericidal Screen  Academic Article
• Development of anti-cancer drugs.  Academic Article
• Effects of Bioisosteric Fluorine in Synthetic Cannabinoid Designer Drugs JWH-018, AM-2201, UR-144, XLR-11, PB-22, 5F-PB-22, APICA, and STS-135  Academic Article
• Efficient production of recombinant IL-21 proteins for pre-clinical studies by a two-step dilution refolding method.  Academic Article
• Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium falciparum to artemisinins  Academic Article
• Improving Combination Osteoporosis Therapy in a Preclinical Model of Heightened Osteoanabolism  Academic Article
• Inhibition of mTOR Signaling With Rapamycin Regresses Established Cardiac Hypertrophy Induced by Pressure Overload  Academic Article
• Inhibitors of human indoleamine 2,3-dioxygenase identified with a target-based screen in yeast  Academic Article
• Materials for stem cell factories of the future  Academic Article
• Modifying Culture Conditions in Chemical Library Screening Identifies Alternative Inhibitors of Mycobacteria  Academic Article
• Nicotiana alata Defensin Chimeras Reveal Differences in the Mechanism of Fungal and Tumor Cell Killing and an Enhanced Antifungal Variant  Academic Article
• Optimisation of an in vitro antifungal protein assay for the screening of potential antifungal proteins against Leptosphaeria maculans  Academic Article
• Oral administration of immunoglobulin G-enhanced colostrum alleviates insulin resistance and liver injury and is associated with alterations in natural killer T cells  Academic Article
• Pegylation of High-Density Lipoprotein Decreases Plasma Clearance and Enhances Antiatherogenic Activity  Academic Article
• Pharmacology of Indole and Indazole Synthetic Cannabinoid Designer Drugs AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, ADBICA, and 5F-ADBICA  Academic Article
• Potent inhibition of scrapie prion replication in cultured cells by bis-acridines  Academic Article
• Preclinical Evaluation of Monoclonal Antibody 14C5 for Targeting Pancreatic Cancer  Academic Article
• Preclinical toxicological assessment of a novel monoclonal antibody targeting human platelet-derived growth factor CC (PDGF-CC) in PDGF-CChum mice  Academic Article
• Prediction of drug absorption based on immobilized artificial membrane (IAM) chromatography separation and calculated molecular descriptors  Academic Article
• Preliminary evaluation of a load-bearing BMP-2 carrier for segmental defect regeneration  Conference Paper
• Probing the structure of Leishmania major DHFR TS and structure based virtual screening of peptide library for the identification of anti-leishmanial leads  Academic Article
• Receptor occupancy imaging studies in oncology drug development  Academic Article
• Selection of an adjuvant for vaccination with the malaria antigen, MSA-2  Academic Article
• Selective Intracellular Release of Copper and Zinc Ions from Bis(thiosemicarbazonato) Complexes Reduces Levels of Alzheimer Disease Amyloid-β Peptide  Academic Article
• Synthesis and preliminary screening of novel indole-3-methanamines as 5-HT4 receptor ligands  Academic Article
• Synthesis, identification and antiplatelet evaluation of 2-morpholino substituted benzoxazines  Academic Article
• Systematic discovery of multicomponent therapeutics  Academic Article
• Targeting the chromosome partitioning protein ParA in tuberculosis drug discovery  Academic Article
• The A/T-specific DNA alkylating agent adozelesin inhibits Plasmodium falciparum growth in vitro and protects mice against Plasmodium chabaudi adami infection  Academic Article
• The Use of Experimental Murine Models to Assess Novel Agents of Hematopoietic Stem and Progenitor Cell Mobilization  Academic Article
• The effect of mitomycin c treatment of infected erythrocytes on infection with Babesia microti and Babesia rodhaini in mice  Academic Article
• Towards effective and safe thrombolysis and thromboprophylaxis  Academic Article
• Unbiased screening of marine sponge extracts for anti-inflammatory agents combined with chemical genomics identifies girolline as an inhibitor of protein synthesis  Academic Article
• Updating the guidelines for data transparency in the British Journal of Pharmacology - data sharing and the use of scatter plots instead of bar charts  Editorial Article