ErbB Receptors
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A Phase I/II Study of Erlotinib in Combination with the Anti-Insulin-Like Growth Factor-1 Receptor Monoclonal Antibody IMC-A12 (Cixutumumab) in Patients with Advanced Non-small Cell Lung Cancer Academic Article
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A Randomized Phase II/III Study of Dalotuzumab in Combination With Cetuximab and Irinotecan in Chemorefractory, KRAS Wild-Type, Metastatic Colorectal Cancer Academic Article
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A monoclonal antibody recognizing human cancers with amplification/overexpression of the human epidermal growth factor receptor Academic Article
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A phase I clinical trial with monoclonal antibody ch806 targeting transitional state and mutant epidermal growth factor receptors Academic Article
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A truncated soluble epidermal growth factor receptor-Fc fusion ligand trap displays anti-tumour activityin vivo Academic Article
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ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling Academic Article
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Activation of Src induces mitochondrial localisation of de2-7EGFR (EGFRvIII) in glioma cells: implications for glucose metabolism Academic Article
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Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide Academic Article
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Activation of the Ras/Mitogen-Activated Protein Kinase Pathway by Kinase-Defective Epidermal Growth Factor Receptors Results in Cell Survival but Not Proliferation Academic Article
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Afatinib for the treatment of patients with EGFR-positive non-small cell lung cancer Academic Article
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An A13 Repeat within the 3'-Untranslated Region of Epidermal Growth Factor Receptor (EGFR) Is Frequently Mutated in Microsatellite Instability Colon Cancers and Is Associated with Increased EGFR Expression Academic Article
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Analysis of Grb7 Recruitment by Heregulin-activated erbB Receptors Reveals a Novel Target Selectivity for erbB3 Academic Article
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Anti-EGFR therapeutic efficacy correlates directly with inhibition of STAT3 activity Academic Article
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Antibodies specifically targeting a locally misfolded region of tumor associated EGFR Academic Article
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Antibody–drug conjugates in glioblastoma therapy: the right drugs to the right cells Academic Article
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Antitumor efficacy of cytotoxic drugs and the monoclonal antibody 806 is enhanced by the EGF receptor inhibitor AG1478 Academic Article
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Are we ready to restrict EGFR therapy to quadruple-negative colorectal cancer? Academic Article
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Associations between the IASLC/ATS/ERS lung adenocarcinoma classification and EGFR and KRAS mutations Academic Article
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CR1/CR2 Interactions Modulate the Functions of the Cell Surface Epidermal Growth Factor Receptor Academic Article
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Characterization of ABBV-221, a Tumor-Selective EGFR-Targeting Antibody Drug Conjugate Academic Article
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Characterization of ABT-806, a humanized tumor-specific anti-EGFR monoclonal antibody Academic Article
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Colon Cancer Cells Adhesion and Spreading on Autocrine Laminin-10 Is Mediated by Multiple Integrin Receptors and Modulated by EGF Receptor Stimulation Academic Article
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Combination osimertinib and gefitinib in C797S and T790M EGFR- mutated non–small cell lung cancer Academic Article
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Combined gene expression and proteomic analysis of EGF induced apoptosis in A431 cells suggests multiple pathways trigger apoptosis Academic Article
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Comparative survival benefit of currently licensed second or third line treatments for epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) negative advanced or metastatic non-small cell lung cancer: a systematic review and secondary analysis of trials Academic Article
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Comparison of Biomarker Assays for EGFR: Implications for Precision Medicine in Patients with Glioblastoma Academic Article
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Control of glioblastoma tumorigenesis by feed-forward cytokine signaling Academic Article
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Control of mammary stem cell function by steroid hormone signalling Academic Article
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De novo
activating epidermal growth factor mutations (EGFR
) in small-cell lung cancer Comment
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Determination of the Exact Molecular Requirements for Type 1 Angiotensin Receptor Epidermal Growth Factor Receptor Transactivation and Cardiomyocyte Hypertrophy Academic Article
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Determining the limit of detection of surface bound antibody Academic Article
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Differential and synergistic effects of epidermal growth factor receptor antibodies on unliganded ErbB dimers and oligomers Academic Article
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Differential regulation of protein tyrosine kinase signalling by Dock and the PTP61F variants Academic Article
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Digital PCR of genomic rearrangements for monitoring circulating tumour DNA Conference Paper
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Dual targeting of the epidermal growth factor receptor using the combination of cetuximab and erlotinib: preclinical evaluation and results of the phase II DUX study in chemotherapy-refractory, advanced colorectal cancer Academic Article
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EGFR and KRAS mutations do not enrich for the activation of IL-6, JAK1 or phosphorylated STAT3 in resected lung adenocarcinoma Academic Article
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EGFR gene copy number alterations are not a useful screening tool for predicting EGFR mutation status in lung adenocarcinoma Academic Article
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Efficacy of depatuxizumab mafodotin (ABT-414) monotherapy in patients with EGFR-amplified, recurrent glioblastoma: results from a multi-center, international study Academic Article
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Engineering and characterisation of chimeric monoclonal antibody 806 (ch806) for targeted immunotherapy of tumours expressing de2-7 EGFR or amplified EGFR Academic Article
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Enhanced Efficacy of Radioimmunotherapy with 90Y-CHX-A''-DTPA-hu3S193 by Inhibition of Epidermal Growth Factor Receptor (EGFR) Signaling with EGFR Tyrosine Kinase Inhibitor AG1478 Conference Paper
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Epidermal Growth Factor Receptor Extracellular Domain Mutations in Glioblastoma Present Opportunities for Clinical Imaging and Therapeutic Development Academic Article
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Epidermal growth factor receptor (EGFR)-targeted therapies in mesothelioma Academic Article
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Epidermal growth factor receptor-targeted lipid nanoparticles retain self-assembled nanostructures and provide high specificity Academic Article
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Epidermal growth factor receptor: mechanisms of activation and signalling Academic Article
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Expression of c-erbB receptors, heregulin and oestrogen receptor in human breast cell lines Academic Article
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Fc-gamma Receptor Polymorphisms, Cetuximab Therapy, and Survival in the NCIC CTG CO.17 Trial of Colorectal Cancer Academic Article
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First in human nanotechnology doxorubicin delivery system to target epidermal growth factor receptors in recurrent glioblastoma Academic Article
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Gefitinib and Pemetrexed Improve Survival in EGFR-Mutated NSCLC — Tarring all Patients With the Same Brush? Academic Article
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Gefitinib-Induced Killing of NSCLC Cell Lines Expressing Mutant EGFR Requires BIM and Can Be Enhanced by BH3 Mimetics Academic Article
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Geminin and Brahma act antagonistically to regulate EGFR–Ras–MAPK signaling in Drosophila Academic Article
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Genomic and Biological Characterization of Exon 4 KRAS Mutations in Human Cancer Academic Article
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Germline polymorphisms as biomarkers of tumor response in colorectal cancer patients treated with anti-EGFR monoclonal antibodies: a systematic review and meta-analysis Academic Article
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Global protein profiling reveals anti-EGFR monoclonal antibody 806-modulated proteins in A431 tumor xenografts Academic Article
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Growth suppression of intracranial xenografted glioblastomas overexpressing mutant epidermal growth factor receptors by systemic administration of monoclonal antibody (mAb) 806, a novel monoclonal antibody directed to the receptor Academic Article
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HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer Academic Article
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Heregulin (HRG)-induced mitogenic signaling and cytotoxic activity of a HRG/PE40 ligand toxin in human breast cancer cells Academic Article
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High rates of albuminuria but not of low eGFR in urban Indigenous Australians: The DRUID study Academic Article
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High resolution melting analysis for rapid and sensitive EGFR and KRAS mutation detection in formalin fixed paraffin embedded biopsies Academic Article
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Identification of the Epitope for the Epidermal Growth Factor Receptor-specific Monoclonal Antibody 806 Reveals That It Preferentially Recognizes an Untethered Form of the Receptor Academic Article
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Immuno-PET Quantitation of de2-7 Epidermal Growth Factor Receptor Expression in Glioma Using 124I-IMP-R4-Labeled Antibody ch806 Academic Article
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In Reply to Leone Letter
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Internalization, Intracellular Trafficking, Biodistribution of Monoclonal Antibody 806: A Novel Anti-Epidermal Growth Factor Receptor Antibody Academic Article
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Ligand binding induces a conformational change in epidermal growth factor receptor dimers Academic Article
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Local Ablative Therapy of Oligoprogressive Disease Prolongs Disease Control by Tyrosine Kinase Inhibitors in Oncogene-Addicted Non–Small-Cell Lung Cancer Academic Article
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MAb 806 Enhances the Efficacy of Ionizing Radiation in Glioma Xenografts Expressing the de2-7 Epidermal Growth Factor Receptor Academic Article
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Mechanisms of Resistance to Crizotinib in Patients withALKGene Rearranged Non–Small Cell Lung Cancer Academic Article
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Mesenchymal Stem Cells Deliver Exogenous MicroRNA-let7c via Exosomes to Attenuate Renal Fibrosis Academic Article
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Monoclonal antibody 806 inhibits the growth of tumor xenografts expressing either the de2-7 or amplified epidermal growth factor receptor (EGFR) but not wild-type EGFR Academic Article
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Novel monoclonal antibody specific for the de2-7 epidermal growth factor receptor (EGFR) that also recognizes the EGFR expressed in cells containing amplification of the EGFR gene Academic Article
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Oncogene status predicts patterns of metastatic spread in treatment-naive nonsmall cell lung cancer Academic Article
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Oncogenic dependence of glioma cells on kish/TMEM167A regulation of vesicular trafficking Academic Article
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Optimisation of the RT-PCR detection of immunomagnetically enriched carcinoma cells Academic Article
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Overexpression of multiple oncogenes related to histological grade of astrocytic glioma Academic Article
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PIK3CA Mutation/PTEN Expression Status Predicts Response of Colon Cancer Cells to the Epidermal Growth Factor Receptor Inhibitor Cetuximab Academic Article
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PTEN gene expression and mutations in the PIK3CA gene as predictors of clinical benefit to anti-epidermal growth factor receptor antibody therapy in patients with KRAS wild-type metastatic colorectal cancer Academic Article
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Preclinical analysis of the analinoquinazoline AG1478, a specific small molecule inhibitor of EGF receptor tyrosine kinase Academic Article
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Profile of epidermal growth factor receptor (EGFr) expression in human malignancies: effects of exposure to EGF and its biological influence on established human tumour cell lines. Academic Article
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Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal transduction components Academic Article
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Rat epidermal growth factor: complete amino acid sequence. Homology with the correspondence murine and human proteins; isolation of a form truncated at both ends with full in vitro biological activity Academic Article
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Relationship Between Colorectal Cancer Biomarkers and Response to Epidermal Growth Factor Receptor Monoclonal Antibodies Academic Article
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Safety and efficacy of depatuxizumab mafodotin +
temozolomide in patients with EGFR-amplified,
recurrent glioblastoma: results from an international
phase I multicenter trial Academic Article
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Strategies for Overcoming Inherent and Acquired Resistance to EGFR Inhibitors by Targeting Downstream Effectors in the RAS/PI3K Pathway Academic Article
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Surface Adsorbed Antibody Characterization Using ToF-SIMS with Principal Component Analysis and Artificial Neural Networks Academic Article
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Synthesis, biodistribution and effects of farnesyltransferase inhibitor therapy on tumour uptake in mice of 99mTc labelled epidermal growth factor Academic Article
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Targeting a unique EGFR epitope with monoclonal antibody 806 activates NF-κB and initiates tumour vascular normalization Academic Article
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Targeting of a conformationally exposed, tumor-specific epitope of EGFR as a strategy for cancer therapy Academic Article
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Telomere length is a novel predictive biomarker of sensitivity to anti-EGFR therapy in metastatic colorectal cancer Academic Article
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Temporal changes of EGFR mutations and T790M levels in tumour and plasma DNA following AZD9291 treatment Academic Article
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The EGFRvIII variant in glioblastoma multiforme Academic Article
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The Efficacy of Epidermal Growth Factor Receptor-Specific Antibodies against Glioma Xenografts Is Influenced by Receptor Levels, Activation Status, and Heterodimerization Academic Article
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The Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor AG1478 Increases the Formation of Inactive Untethered EGFR Dimers Academic Article
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The Phosphoprotein StarD10 Is Overexpressed in Breast Cancer and Cooperates with ErbB Receptors in Cellular Transformation Academic Article
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The Plasticity of Oncogene Addiction: Implications for Targeted Therapies Directed to Receptor Tyrosine Kinases Academic Article
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The antitumor monoclonal antibody 806 recognizes a high‐mannose form of the EGF receptor that reaches the cell surface when cells over‐express the receptor Academic Article
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The clinical relevance of pathologic subtypes in metastatic lung adenocarcinoma Academic Article
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The epidermal growth factor receptor variant III (EGFRvIII): Where wild things are altered Academic Article
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The tumor-specific de2–7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR Academic Article
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Therapeutic anti-EGFR antibody 806 generates responses in murine de novo EGFR mutant–dependent lung carcinomas Academic Article
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Therapeutic efficacy of177Lu-CHX-A″-DTPA-hu3S193 radioimmunotherapy in prostate cancer is enhanced by EGFR inhibition or docetaxel chemotherapy Academic Article
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Therapeutic targeting of the epidermal growth factor receptor in human cancer Academic Article
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Treatment of Human Tumor Xenografts with Monoclonal Antibody 806 in Combination with a Prototypical Epidermal Growth Factor Receptor-Specific Antibody Generates Enhanced Antitumor Activity Academic Article