subject area of

• 2D-DIGE analysis of sera from transgenic mouse models reveals novel candidate protein biomarkers for human gastric cancer  Academic Article
• A 19S proteasomal subunit cooperates with an ERK MAPK-regulated degron to regulate accumulation of Fra-1 in tumour cells  Academic Article
• A Compendium of Potential Biomarkers of Pancreatic Cancer  Academic Article
• A hypermorphic epithelial beta-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations  Academic Article
• A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma  Academic Article
• ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer  Academic Article
• ARHGAP8 is a novel member of the RHOGAP family related to ARHGAP1/CDC42GAP/p50RHOGAP: mutation and expression analyses in colorectal and breast cancers  Academic Article
• ATF3 Repression of BCL-X L Determines Apoptotic Sensitivity to HDAC Inhibitors across Tumor Types  Academic Article
• Aberrant DNA methylation but not mutation of CITED4 is associated with alteration of HIF-regulated genes in breast cancer  Academic Article
• Aberrant DNA methylation in colorectal cancer: What should we target?  Academic Article
• Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers  Academic Article
• Aberrant p53 Expression Does Not Correlate with the Prognosis in Anaplastic Astrocytoma  Academic Article
• Altered NKp30, NKp46, NKG2D, and DNAM-1 Expression on Circulating NK Cells Is Associated with Tumor Progression in Human Gastric Cancer  Academic Article
• Altered expression and splicing of ESRP1 in malignant melanoma correlates with epithelial- mesenchymal status and Tumor-Associated immune cytolytic activity  Academic Article
• Analysis of Ras-induced oncogenic transformation of NIH-3T3 cells using differential-display 2-DE proteomics  Academic Article
• Annexin A1 influences in breast cancer: Controversies on contributions to tumour, host and immunoediting processes  Academic Article
• Annexin-1 signals mitogen-stimulated breast tumor cell proliferation by activation of the formyl peptide receptors (FPRs) 1 and 2  Academic Article
• Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1  Academic Article
• Anti-apoptotic mcl-1 is essential for the development and sustained growth of acute myeloid leukemia  Academic Article
• Antibody inhibiting enzymatic activity of tumour-associated carbonic anhydrase isoform IX  Academic Article
• Apoptotic Sensitivity of Colon Cancer Cells to Histone Deacetylase Inhibitors Is Mediated by an Sp1/Sp3-Activated Transcriptional Program Involving Immediate-Early Gene Induction  Academic Article
• Application of Gene Expression Profiling to Colon Cell Maturation, Transformation and Chemoprevention  Conference Paper
• Artemin-Stimulated Progression of Human Non-Small Cell Lung Carcinoma Is Mediated by BCL2  Academic Article
• Auranofin is a potent suppressor of osteosarcoma metastasis.  Academic Article
• BRAF V600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells  Academic Article
• BTB-Zinc Finger Oncogenes Are Required for Ras and Notch-Driven Tumorigenesis in Drosophila  Academic Article
• Bcl-2, Bcl-x L, and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells  Academic Article
• Bioenergetic differences selectively sensitize tumorigenic liver progenitor cells to a new gold(I) compound  Academic Article
• Biomarkers of 5-fu response in colon cancer [Brief Commentary]  Comment
• Bone morphogenetic protein-7 induces telomerase inhibition, telomere shortening, breast cancer cell senescence, and death via Smad3 (FASEB Journal (2009) DOI: 10.1096/fj.08-119529)  Academic Article
• Brief report: Stem cell media culture of melanoma results in the induction of a nonrepresentative neural expression profile  Academic Article
• By moonlighting in the nucleus, Villin regulates epithelial plasticity  Academic Article
• CLL cells are resistant to smac mimetics because of an inability to form a ripoptosome complex.  Academic Article
• CT-X antigen expression in human breast cancer  Academic Article
• Can we accurately report PTEN status in advanced colorectal cancer?  Academic Article
• Cancer-associated fibroblast-secreted CXCL16 attracts monocytes to promote stroma activation in triple-negative breast cancers  Academic Article
• Cellular Mechanisms Underlying Complete Hematological Response of Chronic Myeloid Leukemia to BRAF and MEK1/2 Inhibition in a Patient with Concomitant Metastatic Melanoma  Academic Article
• Characterization of a novel breast cancer cell line derived from a metastatic bone lesion of a breast cancer patient  Academic Article
• Chromatin states define tumour-specific T cell dysfunction and reprogramming  Academic Article
• Clinical utility of patient-derived xenografts to determine biomarkers of prognosis and map resistance pathways in EGFR-mutant lung adenocarcinoma  Academic Article
• Colorectal cancer cell line proteomes are representative of primary tumors and predict drug sensitivity  Academic Article
• Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer  Academic Article
• Conditional Overexpression of Liver Receptor Homolog-1 in Female Mouse Mammary Epithelium Results in Altered Mammary Morphogenesis via the Induction of TGF-β  Academic Article
• Confluence-Induced Squamous Differentiation Is Not Accompanied by Changes in H3K27me3 Repressive Epigenetic Mark  Academic Article
• Control of glioblastoma tumorigenesis by feed-forward cytokine signaling  Academic Article
• Cox-2 Promotes Chromogranin A Expression and Bioactivity: Evidence for a Prostaglandin E 2 -Dependent Mechanism and the Involvement of a Proximal Cyclic Adenosine 5′-Monophosphate-Responsive Element  Academic Article
• Cysteine cathepsin activity suppresses osteoclastogenesis of myeloid-derived suppressor cells in breast cancer  Academic Article
• DUSP5 is methylated in CIMP-high colorectal cancer but is not a major regulator of intestinal cell proliferation and tumorigenesis  Academic Article
• Deep Sequencing of RNA from Three Different Extracellular Vesicle (EV) Subtypes Released from the Human LIM1863 Colon Cancer Cell Line Uncovers Distinct Mirna-Enrichment Signatures  Academic Article
• Deregulation of MYCN, LIN28B and LET7 in a Molecular Subtype of Aggressive High-Grade Serous Ovarian Cancers  Academic Article
• Determining epithelial contribution to in vivo mesenchymal tumour expression signature using species-specific microarray profiling analysis of xenografts  Academic Article
• Differential Regulation of Gastric Tumor Growth by Cytokines That Signal Exclusively Through the Coreceptor gp130  Academic Article
• Differential mechanisms of CDKN2A (p16) alteration in oral tongue squamous cell carcinomas and correlation with patient outcome  Academic Article
• Discovery and analysis of consistent active sub-networks in cancers  Conference Paper
• Disruption of prion protein-HOP engagement impairs glioblastoma growth and cognitive decline and improves overall survival  Academic Article
• Disruption of the SRC-1 gene in mice suppresses breast cancer metastasis without affecting primary tumor formation  Academic Article
• Dissecting HDAC3-mediated tumor progression  Academic Article
• Distant Metastasis in Breast Cancer: Molecular Mechanisms and Therapeutic Targets  Academic Article
• Distinct nuclear receptor expression in stroma adjacent to breast tumors  Academic Article
• Down-regulation of β-catenin TCF signaling is linked to colonic epithelial cell differentiation  Academic Article
• Dual targeting of bromodomain and extraterminal domain proteins, and WNT or MAPK signaling, Inhibits c-MYC expression and proliferation of colorectal cancer cells  Academic Article
• Dysregulation of the repressive H3K27 trimethylation mark in head and neck squamous cell carcinoma contributes to dysregulated squamous differentiation  Academic Article
• E6AP promotes prostate cancer by reducing p27 expression  Academic Article
• ELF3, ELF5, EHF and SPDEF transcription factors in tissue homeostasis and cancer  Academic Article
• Elevated Dnmt3a Activity Promotes Polyposis in ApcMin Mice by Relaxing Extracellular Restraints on Wnt Signaling  Academic Article
• Emerging roles for IL-11 signaling in cancer development and progression: Focus on breast cancer  Academic Article
• Endogenous bcl-2 is not required for the development of E -myc induced B-cell lymphoma  Academic Article
• Entamoeba histolytica: Target Cells Killed by Trophozoites Undergo DNA Fragmentation Which Is Not Blocked by Bcl-2  Academic Article
• Epiregulin gene expression as a biomarker of benefit from cetuximab in the treatment of advanced colorectal cancer  Academic Article
• Expression of stress response protein glucose regulated protein-78 mediated by c-Myb  Academic Article
• Expression of the MAGE-1 gene in human hepatocellular carcinomas  Academic Article
• Extracellular vesicles secreted by highly metastatic clonal variants of osteosarcoma preferentially localize to the lungs and induce metastatic behaviour in poorly metastatic clones  Academic Article
• Finding edging genes from microarray data  Academic Article
• Fn14: a new player in cancer-induced cachexia  Academic Article
• Fra-1 controls motility of bladder cancer cells via transcriptional upregulation of the receptor tyrosine kinase AXL  Academic Article
• Functional and genomic characterisation of a xenograft model system for the study of metastasis in triple-negative breast cancer  Academic Article
• Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer  Academic Article
• Genome-wide transcription responses to synchrotron microbeam radiotherapy  Academic Article
• Genomic analysis of a spontaneous model of breast cancer metastasis to bone reveals a role for the extracellular matrix  Academic Article
• Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer  Academic Article
• Global protein profiling reveals anti-EGFR monoclonal antibody 806-modulated proteins in A431 tumor xenografts  Academic Article
• Glucocorticoid resistance of migration and gene expression in a daughter MDA-MB-231 breast tumour cell line selected for high metastatic potential  Academic Article
• Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) induces cancer cell senescence by interacting with telomerase RNA component  Academic Article
• Growth suppression of intracranial xenografted glioblastomas overexpressing mutant epidermal growth factor receptors by systemic administration of monoclonal antibody (mAb) 806, a novel monoclonal antibody directed to the receptor  Academic Article
• H pylori status and angiogenesis factors in human gastric carcinoma  Academic Article
• HDAC4 Promotes Growth of Colon Cancer Cells via Repression of p21  Academic Article
• HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer  Academic Article
• Hallmarks of response to immune checkpoint blockade  Academic Article
• Heterogeneity of Jagged1 expression in human and mouse intestinal tumors: implications for targeting Notch signaling  Academic Article
• Highly expressed genes in rapidly proliferating tumor cells as new targets for colorectal cancer treatment  Academic Article
• Identification of a Novel Proto-oncogenic Network in Head and Neck Squamous Cell Carcinoma  Academic Article
• Identifying and targeting determinants of melanoma cellular invasion  Academic Article
• Immuno-PET Quantitation of de2-7 Epidermal Growth Factor Receptor Expression in Glioma Using 124I-IMP-R4-Labeled Antibody ch806  Academic Article
• Immunohistochemical and Molecular Analysis of Human Melanomas for Expression of the Human Cancer-Testis Antigens NY-ESO-1 and LAGE-1  Academic Article
• In vivo growth of a murine lymphoma cell line alters regulation of expression of HSP72.  Academic Article
• Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression  Academic Article
• Inhibition of cathepsin proteases attenuates migration and sensitizes aggressive N-Myc amplified human neuroblastoma cells to doxorubicin  Academic Article
• Integrated mutation, copy number and expression profiling in resectable non-small cell lung cancer  Academic Article
• Intermittent hypoxia induces a metastatic phenotype in breast cancer  Academic Article
• Intestinal-specific activatable Myb initiates colon tumorigenesis in mice  Academic Article
• Intracellular Trafficking of the K V 1.3 Potassium Channel Is Regulated by the Prodomain of a Matrix Metalloprotease  Academic Article
• Kaiso-Deficient Mice Show Resistance to Intestinal Cancer  Academic Article
• Laminin-511: A multi-functional adhesion protein regulating cell migration, tumor invasion and metastasis  Academic Article
• Loss of CDKN2A expression is a frequent event in primary invasive melanoma and correlates with sensitivity to the CDK4/6 inhibitor PD0332991 in melanoma cell lines  Academic Article
• Loss of NF-κB1 Causes Gastric Cancer with Aberrant Inflammation and Expression of Immune Checkpoint Regulators in a STAT-1-Dependent Manner  Academic Article
• Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling  Academic Article
• Making Sense of HDAC2 Mutations in Colon Cancer  Academic Article
• Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylation of which is associated with metastasis or hormone receptor status in advanced breast cancer  Academic Article
• Mechanisms of Histone Deacetylase Inhibitor-Regulated Gene Expression in Cancer Cells  Academic Article
• Mechanisms of inactivation of the tumour suppressor gene RHOA in colorectal cancer  Academic Article
• Methylation profiling of ductal carcinoma in situ and its relationship to histopathological features  Academic Article
• Methylation profiling of normal individuals reveals mosaic: Promoter methylation of cancer-associated genes  Academic Article
• MiR-200 can repress breast cancer metastasis through ZEB1-independent but moesin-dependent pathways  Academic Article
• Mitoxantrone Mediates Demethylation and Re-Expression of Cyclin D2, Estrogen Receptor 14.3.3 Sigma In Breast Cancer Cells  Academic Article
• Modulation of gene expression in U251 glioblastoma cells by binding of mutant p53 R273H to intronic and intergenic sequences  Academic Article
• Monoclonal antibody 14C5 targets integrin  v 5  Academic Article
• Monoclonal antibody 806 inhibits the growth of tumor xenografts expressing either the de2-7 or amplified epidermal growth factor receptor (EGFR) but not wild-type EGFR  Academic Article
• Multiple genetic loci modify susceptibility to plasmacytoma-related morbidity in E -v-abl transgenic mice  Academic Article
• Mycoplasma Infection Alters Cancer Stem Cell Properties in Vitro  Academic Article
• N-Cadherin and Keratinocyte Growth Factor Receptor Mediate the Functional Interplay between Ki-RASG12V and p53V143A in Promoting Pancreatic Cell Migration, Invasion, and Tissue Architecture Disruption  Academic Article
• Na+/monocarboxylate transport (SMCT) protein expression correlates with survival in colon cancer: Molecular characterization of SMCT  Academic Article
• No evidence for DNA methylation of von Hippel-Lindau ubiquitin ligase complex genes in breast cancer  Academic Article
• Nonequivalent gene expression and copy number alterations in high-grade serous ovarian cancers with BRCA1 and BRCA2 mutations  Academic Article
• Nonsense Mediated Decay Resistant Mutations Are a Source of Expressed Mutant Proteins in Colon Cancer Cell Lines with Microsatellite Instability  Academic Article
• Novel inhibitors of urokinase-type plasminogen activator and matrix metalloproteinase expression in metastatic cancer cell lines  Academic Article
• Novel monoclonal antibody specific for the de2-7 epidermal growth factor receptor (EGFR) that also recognizes the EGFR expressed in cells containing amplification of the EGFR gene  Academic Article
• Oncogenic Ki-Ras Inhibits the Expression of Interferon-responsive Genes through Inhibition of STAT1 and STAT2 Expression  Academic Article
• Osteopontin increases hepatocellular carcinoma cell growth in a CD44 dependant manner  Academic Article
• Osteosarcoma is characterised by reduced expression of markers of osteoclastogenesis and antigen presentation compared with normal bone  Academic Article
• Oxaliplatin resistance induced by ERCC1 up-regulation is abrogated by siRNA-mediated gene silencing in human colorectal cancer cells  Academic Article
• PHLDA1 expression marks the putative epithelial stem cells and contributes to intestinal tumorigenesis  Academic Article
• PIM-1 kinase expression in adipocytic neoplasms: diagnostic and biological implications  Academic Article
• PR55α-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity  Academic Article
• Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-β-catenin-mediated intestinal tumor growth and regeneration  Academic Article
• Parvin- Inhibits Breast Cancer Tumorigenicity and Promotes CDK9-Mediated Peroxisome Proliferator-Activated Receptor Gamma 1 Phosphorylation  Academic Article
• Physiological Levels of Pik3ca(H1047R) Mutation in the Mouse Mammary Gland Results in Ductal Hyperplasia and Formation of ER alpha-Positive Tumors  Academic Article
• Physiological expression of the PI3K-activating mutation Pik3ca H1047R combines with Apc loss to promote development of invasive intestinal adenocarcinomas in mice  Academic Article
• Powerful differential expression analysis incorporating network topology for next-generation sequencing data  Academic Article
• Presenilin 2 Expression in Neuronal Cells: Induction during Differentiation of Embryonic Carcinoma Cells  Academic Article
• Pro-apoptotic Bim suppresses breast tumor cell metastasis and is a target gene of SNAI2  Academic Article
• Progression of osteosarcoma from a non-metastatic to a metastatic phenotype is causally associated with activation of an autocrine and paracrine uPA axis  Academic Article
• Promoter region methylation does not account for the frequent loss of expression of the Fas gene in colorectal carcinoma  Academic Article
• RHOA inactivation enhances Wnt signalling and promotes colorectal cancer  Academic Article
• Randomized phase II trial of parsatuzumab (Anti‐EGFL7) or placebo in combination with FOLFOX and bevacizumab for first‐line metastatic colorectal cancer  Academic Article
• Re: Gene Expression-Based Prognostic Signatures in Lung Cancer: Ready for Clinical Use?  Academic Article
• Reduced abundance of the E3 ubiquitin ligase E6AP contributes to decreased expression of the INK4/ARF locus in non–small cell lung cancer  Academic Article
• Regulation of Inducible Heparanase Gene Transcription in Activated T Cells by Early Growth Response 1  Academic Article
• Restoration of tumor suppression in prostate cancer by targeting the E3 ligase E6AP  Academic Article
• Retinoic acid effects on an SV-40 large T antigen immortalized adult rat bone cell line  Academic Article
• Role of miRNA in head and neck squamous cell carcinoma  Academic Article
• STAT3 Activation Regulates Growth, Inflammation, and Vascularization in a Mouse Model of Gastric Tumorigenesis  Academic Article
• STC1 expression is associated with tumor growth and metastasis in breast cancer  Academic Article
• Secreted primary human malignant mesothelioma exosome signature reflects oncogenic cargo  Academic Article
• Signal Transducer and Activator of Transcription (STAT)-5A and STAT5B Differentially Regulate Human Mammary Carcinoma Cell Behavior  Academic Article
• Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape  Academic Article
• Small RNA deep sequencing discriminates subsets of extracellular vesicles released by melanoma cells - Evidence of unique microRNA cargos  Academic Article
• Snail is a repressor of RKIP transcription in metastatic prostate cancer cells  Academic Article
• Sp1 and CREB Mediate Gastrin-dependent Regulation of Chromogranin A Promoter Activity in Gastric Carcinoma Cells  Academic Article
• Subdividing globally important zones based on data distribution across multiple genome fragments  Academic Article
• Subtypes of familial breast tumours revealed by expression and copy number profiling  Academic Article
• Sulindac modulates secreted protein expression from LIM1215 colon carcinoma cells prior to apoptosis  Academic Article
• Symplekin promotes tumorigenicity by up-regulating claudin-2 expression  Academic Article
• Systems analysis identifies miR-29b regulation of invasiveness in melanoma  Academic Article
• Targeted therapies in hematological malignancies using therapeutic monoclonal antibodies against Eph family receptors  Academic Article
• Targeting BCL-2 to enhance vulnerability to therapy in estrogen receptor-positive breast cancer  Academic Article
• Targeting EphA3 inhibits cancer growth by disrupting the tumor stromal microenvironment  Academic Article
• Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53  Academic Article
• Targeting of the Tumor Suppressor GRHL3 by a miR-21-Dependent Proto-Oncogenic Network Results in PTEN Loss and Tumorigenesis  Academic Article
• The Interleukin-6 Family Cytokine Interleukin-11 Regulates Homeostatic Epithelial Cell Turnover and Promotes Gastric Tumor Development  Academic Article
• The Ludwig Institute for Cancer Research Melbourne Melanoma Cell Line Panel  Academic Article
• The Role of Cancer-Testis Antigens as Predictive and Prognostic Markers in Non-Small Cell Lung Cancer  Academic Article
• The Tasmanian Devil Transcriptome Reveals Schwann Cell Origins of a Clonally Transmissible Cancer  Academic Article
• The epidermal growth factor receptor variant III (EGFRvIII): Where wild things are altered  Academic Article
• The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation  Academic Article
• The orphan nuclear receptor LRH-1 and ERα activate GREB1 expression to induce breast cancer cell proliferation  Academic Article
• The transcription cofactor c-JUN mediates phenotype switching and BRAF inhibitor resistance in melanoma  Academic Article
• Thirty years of BCL-2: translating cell death discoveries into novel cancer therapies  Academic Article
• Tissue-specific regulation of aromatase promoter II by the orphan nuclear receptor LRH-1 in breast adipose stromal fibroblasts  Academic Article
• Transcriptome and long noncoding RNA sequencing of three extracellular vesicle subtypes released from the human colon cancer LIM1863 cell line  Academic Article
• Transketolase-like 1 ectopic expression is associated with DNA hypomethylation and induces the Warburg effect in melanoma cells  Academic Article
• Treatment of Human Tumor Xenografts with Monoclonal Antibody 806 in Combination with a Prototypical Epidermal Growth Factor Receptor-Specific Antibody Generates Enhanced Antitumor Activity  Academic Article
• Trefoil Factor 3 Is Oncogenic and Mediates Anti-Estrogen Resistance in Human Mammary Carcinoma  Academic Article
• Tumor Antigen Expression in Melanoma Varies According to Antigen and Stage  Academic Article
• Tumor-Specific Hsp70 Plasma Membrane Localization Is Enabled by the Glycosphingolipid Gb3  Academic Article
• Tumour but not stromal expression of β 3 integrin is essential, and is required early, for spontaneous dissemination of bone-metastatic breast cancer  Academic Article
• Tumour-specific distribution of BRCA1 promoter region methylation supports a pathogenetic role in breast and ovarian cancer  Academic Article
• Upregulation of P-glycoprotein in rat hepatoma ρ°cells: Implications for drug-DNA interactions  Academic Article
• Variable FZD7 expression in colorectal cancers indicates regulation by the tumour microenvironment  Academic Article
• Villin expression Is frequently lost in poorly differentiated colon cancer  Academic Article
• Widespread FRA1-dependent control of mesenchymal transdifferentiation programs in colorectal cancer cells  Academic Article
• c-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis  Academic Article
• p21 ^WAF1/cip1 is an important determinant of intestinal cell response to sulindac in vitro and in vivo  Academic Article
• scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila  Academic Article
• β-Catenin/Tcf-4 Inhibition After Progastrin Targeting Reduces Growth and Drives Differentiation of Intestinal Tumors  Academic Article
• β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells  Academic Article