Inhibitor of Apoptosis Proteins
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A cloning method to identify caspases and their regulators in yeast: Identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1 Academic Article
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Analysis of candidate antagonists of IAP-mediated caspase inhibition using yeast reconstituted with the mammalian Apaf-1-activated apoptosis mechanism Academic Article
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Antagonism of IAPs enhances CAR T-cell efficacy Academic Article
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Anti-apoptotic potential of insect cellular and viral IAPs in mammalian cells Academic Article
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Asymmetric Recruitment of cIAPs by TRAF2 Academic Article
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Bioenergetic differences selectively sensitize tumorigenic liver progenitor cells to a new gold(I) compound Academic Article
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CLL cells are resistant to smac mimetics because of an inability to form a ripoptosome complex. Academic Article
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Caspase inhibitors Academic Article
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Caspase inhibitors: viral, cellular and chemical Academic Article
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Caspase-2 is resistant to inhibition by inhibitor of apoptosis proteins (IAPs) and can activate caspase-7 Academic Article
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Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment Academic Article
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Cellular Inhibitor of Apoptosis Protein-1 (cIAP1) Can Regulate E2F1 Transcription Factor-mediated Control of Cyclin Transcription Academic Article
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Cellular inhibitor of apoptosis proteins prevent clearance of hepatitis B virus Academic Article
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Characterization of the DrosophilaCaspase, DAMM Academic Article
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Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors. Academic Article
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Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways Academic Article
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DNA damage and S phase-dependent E2F1 stabilization requires the cIAP1 E3-ubiquitin ligase and is associated with K63-poly-ubiquitination on lysine 161/164 residues Academic Article
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Debcl, a Proapoptotic Bcl-2 Homologue, Is a Component of the Drosophila melanogaster Cell Death Machinery Academic Article
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Deletion of cIAP1 and cIAP2 in murine B lymphocytes constitutively activates cell survival pathways and inactivates the germinal center response Academic Article
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Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance Academic Article
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Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP Academic Article
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E2F1 Binds to the Peptide-Binding Groove within the BIR3 Domain of cIAP1 and Requires cIAP1 for Chromatin Binding Academic Article
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Eliminating hepatitis B by antagonizing cellular inhibitors of apoptosis Academic Article
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HtrA2 Promotes Cell Death through Its Serine Protease Activity and Its Ability to Antagonize Inhibitor of Apoptosis Proteins Academic Article
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HtrA2/Omi, a Sheep in Wolf's Clothing Academic Article
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IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis Academic Article
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IAP Family of Cell Death and Signaling Regulators Chapter
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IAP antagonists sensitize murine osteosarcoma cells to killing by TNF alpha Academic Article
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IAP et Rho : enfin connectées Academic Article
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IAP gene deletion and conditional knockout models Academic Article
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IAPS and ubiquitylation Academic Article
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IAPs Regulate Distinct Innate Immune Pathways to Co-ordinate the Response to Bacterial Peptidoglycans Academic Article
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IAPs and cell death Chapter
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IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-κB as well as cell survival and oncogenesis Academic Article
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IAPs limit activation of RIP kinases by TNF receptor 1 during development Academic Article
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IAPs – the ubiquitin connection Academic Article
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IAPs, RINGs and ubiquitylation Academic Article
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IAPs, TNF, inflammation and Jürg TSCHOPP; A personal perspective Academic Article
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Identification and Validation of Oncogenes in Liver Cancer Using an Integrative Oncogenomic Approach Academic Article
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Identification of DIABLO, a Mammalian Protein that Promotes Apoptosis by Binding to and Antagonizing IAP Proteins Academic Article
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Identification of mammalian mitochondrial proteins that interact with IAPs via N-terminal IAP binding motifs Academic Article
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In TNF-stimulated Cells, RIPK1 Promotes Cell Survival by Stabilizing TRAF2 and cIAP1, which Limits Induction of Non-canonical NF-κB and Activation of Caspase-8* Academic Article
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Inhibition of Bcl-2 or IAP proteins does not provoke mutations in surviving cells Academic Article
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Inhibition of interleukin 1 -converting enzyme-mediated apoptosis of mammalian cells by baculovirus IAP Conference Paper
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Inhibitor of Apoptosis (IAP) Proteins-Modulators of Cell Death and Inflammation Academic Article
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Inhibitor of Apoptosis Proteins (IAPs) Limit RIPK1-Mediated Skin Inflammation Academic Article
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Inhibitor of Apoptosis Proteins Limit RIP3 Kinase-Dependent Interleukin-1 Activation Academic Article
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Inhibitor of apoptosis protein (IAP) antagonists demonstrate divergent immunomodulatory properties in human immune subsets with implications for combination therapy Academic Article
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Inhibitor of apoptosis protein-1 regulates tumor necrosis factor-mediated destruction of intestinal epithelial cells Academic Article
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Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs Academic Article
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Killing Lymphoma with Smac-Mimetics: As Easy as ABC? Academic Article
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Les IAP au cœur de la signalisation NF-κB Academic Article
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Lgl, aPKC, and Crumbs Regulate the Salvador/Warts/Hippo Pathway through Two Distinct Mechanisms Academic Article
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MCMV-mediated Inhibition of the Pro-apoptotic Bak Protein Is Required for Optimal In Vivo Replication Academic Article
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Mammalian mitochondrial IAP binding proteins Academic Article
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Molecular determinants of Smac mimetic induced degradation of cIAP1 and cIAP2 Academic Article
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More Than Cell Death Academic Article
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NF-κB Inhibition Reveals Differential Mechanisms of TNF Versus TRAIL-Induced Apoptosis Upstream or at the Level of Caspase-8 Activation Independent of cIAP2 Academic Article
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New Perspectives in TNF-R1-Induced NF-kappa B Signaling Conference Paper
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PD-L1 and IAPs co-operate to protect tumors from cytotoxic lymphocyte-derived TNF Academic Article
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RIP-in CD95-induced cell death: The control of alternative death receptors pathways by cIAPs Academic Article
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RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL Academic Article
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Recent advances in understanding inhibitor of apoptosis proteins Academic Article
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Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction Academic Article
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Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs Academic Article
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Response to Heard
et al Academic Article
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STRICA, a novel Drosophila melanogaster caspase with an unusual serine/threonine-rich prodomain, interacts with DIAP1 and DIAP2 Academic Article
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Smac Mimetics Activate the E3 Ligase Activity of cIAP1 Protein by Promoting RING Domain Dimerization Academic Article
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Solution structure of a baculoviral inhibitor of apoptosis (IAP) repeat Academic Article
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Structures of the cIAP2 RING Domain Reveal Conformational Changes Associated with Ubiquitin-conjugating Enzyme (E2) Recruitment Academic Article
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Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype Academic Article
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Systematic In Vivo RNAi Analysis Identifies IAPs as NEDD8-E3 Ligases Academic Article
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TRAF2 Must Bind to Cellular Inhibitors of Apoptosis for Tumor Necrosis Factor (TNF) to Efficiently Activate NF-κB and to Prevent TNF-induced Apoptosis Academic Article
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TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα Academic Article
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The Drosophila Caspase Inhibitor DIAP1 Is Essential for Cell Survival and Is Negatively Regulated by HID Academic Article
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The Drosophila caspase DRONC is a glutamate/aspartate protease whose activity is regulated by DIAP1, HID and GRIM Academic Article
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The Drosophila caspase DRONC is regulated by DIAP1 Academic Article
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The Survivin-like C. elegans BIR-1 Protein Acts with the Aurora-like Kinase AIR-2 to Affect Chromosomes and the Spindle Midzone Academic Article
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Tumor Necrosis Factor (TNF) Signaling, but Not TWEAK (TNF-like Weak Inducer of Apoptosis)-triggered cIAP1 (Cellular Inhibitor of Apoptosis Protein 1) Degradation, Requires cIAP1 RING Dimerization and E2 Binding Academic Article
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Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2 Academic Article
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Workshop Summary: Novel Aspects of the Functions of the TRAFs and cIAPs Conference Paper
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XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation Academic Article
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XIAP-deficiency leads to delayed lobuloalveolar development in the mammary gland Academic Article
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cIAP1 regulates TNF-mediated cdc42 activation and filopodia formation Academic Article
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cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1-and RIPK3-dependent manner Academic Article