subject area of

• 2-Deoxygalactose interferes with an intermediate processing stage of memory  Academic Article
• A Common Fold Mediates Vertebrate Defense and Bacterial Attack  Academic Article
• A Division-Linked Mechanism for the Rapid Generation of Ig-Secreting Cells from Human Memory B Cells  Academic Article
• A Family of Helminth Molecules that Modulate Innate Cell Responses via Molecular Mimicry of Host Antimicrobial Peptides  Academic Article
• A Phase I Trial of Humanized Monoclonal Antibody A33 in Patients with Colorectal Carcinoma: Biodistribution, Pharmacokinetics, and Quantitative Tumor Uptake  Academic Article
• A comparative study of the phenotype and proliferative capacity of peripheral blood (PB) CD34⁺cells mobilized by four different protocols and those of steady-phase PB and bone marrow CD34⁺cells  Academic Article
• A phase I radioimmunolocalization trial of humanized monoclonal antibody huA33 in patients with gastric carcinoma  Academic Article
• A33 antigen-deficient mice have defective colonic mucosal repair  Academic Article
• Acquiring signalling specificity from the cytokine receptor gp130  Academic Article
• Activation of Protease-Activated Receptor-2 Leads to Inhibition of Osteoclast Differentiation  Academic Article
• Affinity Maturation of Leukemia Inhibitory Factor and Conversion to Potent Antagonists of Signaling  Academic Article
• An animal model of chronic placental insufficiency: Relevance to neurodevelopmental disorders including schizophrenia  Academic Article
• Analysis of FasL and TRAIL induced apoptosis pathways in glioma cells  Academic Article
• Analysis of the Regulation of the A33 Antigen Gene Reveals Intestine-specific Mechanisms of Gene Expression  Academic Article
• Antigen-Specific T-Cell Responses to a Recombinant Fowlpox Virus Are Dependent on MyD88 and Interleukin-18 and Independent of Toll-Like Receptor 7 (TLR7)- and TLR9-Mediated Innate Immune Recognition  Academic Article
• Arl5b is a Golgi-localised small G protein involved in the regulation of retrograde transport  Academic Article
• Association of a functional polymorphism of the serotonin transporter gene with anxiety-related temperament and behavior problems in children: a longitudinal study from infancy to the mid-teens  Academic Article
• Association of a polymorphism of the dopamine transporter gene with externalizing behavior problems and associated temperament traits: A longitudinal study from infancy to the mid-teens  Academic Article
• Augmented Superoxide Production By Nox2-Containing NADPH Oxidase Causes Cerebral Artery Dysfunction During Hypercholesterolemia  Academic Article
• B cell differentiation and isotype switching is related to division cycle number  Academic Article
• BAFF selectively enhances the survival of plasmablasts generated from human memory B cells  Academic Article
• Bcl-2 Prevents Apoptosis Induced by Perforin and Granzyme B, but Not That Mediated by Whole Cytotoxic Lymphocytes  Academic Article
• Brain infarct volume after permanent focal ischemia is not dependent on Nox2 expression  Academic Article
• CD40 ligand-CD40 interaction in Ig isotype switching in mature and immature human B cells  Academic Article
• CD84 is up-regulated on a major population of human memory B cells and recruits the SH2 domain containing proteins SAP and EAT-2  Academic Article
• Cell division number regulates IgG1 and IgE switching of B cells following stimulation by CD40 ligand and IL-4.  Academic Article
• Changes in plasma membrane Ca-ATPase and stromal interacting molecule 1 expression levels for Ca 2+ signaling in dystrophic mdx mouse muscle  Academic Article
• Characterization of Posttranslational Modifications of Human A33 Antigen, a Novel Palmitoylated Surface Glycoprotein of Human Gastrointestinal Epithelium  Academic Article
• Characterization of mouse A33 antigen, a definitive marker for basolateral surfaces of intestinal epithelial cells  Academic Article
• Chronic aldosterone administration causes Nox2-mediated increases in reactive oxygen species production and endothelial dysfunction in the cerebral circulation  Academic Article
• Colon tumour secretopeptidome: Insights into endogenous proteolytic cleavage events in the colon tumour microenvironment  Academic Article
• Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets  Academic Article
• Constitutive activation of gp130 leads to neuroendocrine differentiation in vitro and in vivo  Academic Article
• Contact-mediated signals and cytokines involved in B-cell activation and isotype switching in pre-B and mature B cells  Academic Article
• Controlling TRAIL-mediated caspase-3 activation  Academic Article
• Cross-Talk between Activated Human NK Cells and CD4+ T Cells via OX40-OX40 Ligand Interactions  Academic Article
• Cytotoxic T lymphocyte–induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis  Academic Article
• Defective Gp130-Mediated Signal Transducer and Activator of Transcription (Stat) Signaling Results in Degenerative Joint Disease, Gastrointestinal Ulceration, and Failure of Uterine Implantation  Academic Article
• Desmoplastic melanoma: comparison of expression of differentiation antigens and cancer testis antigens  Academic Article
• Determination of the Disulfide Structure and N -Glycosylation Sites of the Extracellular Domain of the Human Signal Transducer gp130  Academic Article
• Differential Inhibition of TRAIL-Mediated DR5-DISC Formation by Decoy Receptors 1 and 2  Academic Article
• Differential Regulation of Gastric Tumor Growth by Cytokines That Signal Exclusively Through the Coreceptor gp130  Academic Article
• Differential Role of Serotonergic Projections Arising from the Dorsal and Median Raphe Nuclei in Locomotor Hyperactivity and Prepulse Inhibition  Academic Article
• Differential role of MyD88 and Mal/TIRAP in TLR2-mediated gastric tumourigenesis  Academic Article
• Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE −/− mice  Academic Article
• Display of a Peptide Mimotope on a Crystalline Bacterial Cell Surface Layer (S-layer) Lattice for Diagnosis of Epstein–Barr Virus Infection  Academic Article
• Distinct Roles for Leukemia Inhibitory Factor Receptor α-Chain and gp130 in Cell Type-specific Signal Transduction  Academic Article
• Distribution of the 3' VNTR polymorphism in the human dopamine transporter gene in world populations  Academic Article
• Disulfide Bond Structure and N -Glycosylation Sites of the Extracellular Domain of the Human Interleukin-6 Receptor  Academic Article
• Effects of titanium particle size on osteoblast functions in vitro and in vivo  Academic Article
• Electrophoretic analysis of the novel antigen for the gastrointestinal-specific monoclonal antibody, A33  Conference Paper
• Elevated Dnmt3a Activity Promotes Polyposis in ApcMin Mice by Relaxing Extracellular Restraints on Wnt Signaling  Academic Article
• Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy  Academic Article
• Endothelial NADPH oxidases: which NOX to target in vascular disease?  Academic Article
• Evaluation of a monoclonal IgM antibody for purging of bone marrow for autologous transplantation  Academic Article
• Evidence that nitric oxide inhibits vascular inflammation and superoxide production via a p47 phox -dependent mechanism in mice  Academic Article
• Ex vivo expansion and maturation of peripheral blood CD34⁺cells into the myeloid lineage  Academic Article
• Ex vivo pediatric brain tumors express Fas (CD95) and FasL (CD95L) and are resistant to apoptosis induction  Academic Article
• Fosl1 is a transcriptional target of c-Fos during osteoclast differentiation  Academic Article
• Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130  Academic Article
• Gender Influences Cerebral Vascular Responses to Angiotensin II Through Nox2-Derived Reactive Oxygen Species  Academic Article
• Gesicles: microvesicle cookies for transient information transfer between cells  Academic Article
• Glycoprotein A33 deficiency: A new mouse model of impaired intestinal epithelial barrier function and inflammatory disease  Academic Article
• Helper T cells: delivery of cell contact and lymphokine-dependent signals to B cells  Academic Article
• Hematopoietic abnormalities in mice deficient in gp130-mediated STAT signaling  Academic Article
• Heparan Sulfate Proteoglycans Modulate Monocyte Migration across Cerebral Endothelium  Academic Article
• High affinity interleukin-6 receptor is a hexameric complex consisting of two molecules each of interleukin-6, interleukin-6 receptor, and gp-130  Academic Article
• IL-6 trans-signaling modulates TLR4-dependent inflammatory responses via STAT3  Academic Article
• Identification and Characterization of Two Distinct Truncated Forms of gp130 and a Soluble Form of Leukemia Inhibitory Factor Receptor α-Chain in Normal Human Urine and Plasma  Academic Article
• Identification of two integral membrane proteins of Plasmodium falciparum.  Academic Article
• Imbalanced gp130-Dependent Signaling in Macrophages Alters Macrophage Colony-Stimulating Factor Responsiveness via Regulation of c-fms Expression  Academic Article
• Immuno-PET of human colon xenograft-bearing BALB/c nude mice using ¹²⁴I-CDR-grafted humanized A33 monoclonal antibody  Academic Article
• In vitro sensitivity testing of minimally passaged and uncultured gliomas with TRAIL and/or chemotherapy drugs  Academic Article
• Increased Expression of CD27 on Activated Human Memory B Cells Correlates with Their Commitment to the Plasma Cell Lineage  Academic Article
• Increased NADPH Oxidase Activity, gp91phox Expression, and Endothelium-Dependent Vasorelaxation During Neointima Formation in Rabbits  Academic Article
• Increased recruitment of hematopoietic progenitor cells underlies the ex vivo expansion potential of FLT3 ligand  Academic Article
• Influence of Interleukin-6 (IL-6) Dimerization on Formation of the High Affinity Hexameric IL-6·Receptor Complex  Academic Article
• Influence of Size, Surface, Cell Line, and Kinetic Properties on the Specific Binding of A33 Antigen-Targeted Multilayered Particles and Capsules to Colorectal Cancer Cells  Academic Article
• Influenza A Infection Enhances Cross-Priming of CD8+ T Cells to Cell-Associated Antigens in a TLR7- and Type I IFN-Dependent Fashion  Academic Article
• Inhibition of Nox2 Oxidase Activity Ameliorates Influenza A Virus-Induced Lung Inflammation  Conference Paper
• Integrating signals from IFN-γ and IL-4 by B cells: Positive and negative effects on CD40 ligand-induced proliferation, survival, and division-linked isotype switching to IgG1, IgE, and IgG2a  Academic Article
• Intrinsic Differences in the Proliferation of Naive and Memory Human B Cells as a Mechanism for Enhanced Secondary Immune Responses  Academic Article
• Is nephrocalcin related to the urinary derivative (bikunin) of inter-α-trypsin inhibitor?  Academic Article
• Isolation of a larval surface glycoprotein from Haemonchus contortus and its possible role in evading host immunity  Academic Article
• Jekyll and Hyde: The other life of the death ligand TRAIL  Comment
• Leishmania major: Expression and gene structure of the glycoprotein 63 molecule in virulent and avirulent clones and strains  Academic Article
• Ligand-specific utilization of the extracellular membrane-proximal region of the gp130-related signalling receptors  Academic Article
• Mammary Gland Remodeling Depends on gp130 Signaling through Stat3 and MAPK  Academic Article
• Mechanisms Contributing to Cerebral Infarct Size after Stroke: Gender, Reperfusion, T Lymphocytes, and Nox2-Derived Superoxide  Academic Article
• Mice Deficient in Perforin, CD4+ T Cells, or CD28-Mediated Signaling Maintain the Typical Immunodominance Hierarchies of CD8+ T-Cell Responses to Influenza Virus  Academic Article
• Micro-sequencing strategies for the human A33 antigen, a novel surface glycoprotein of human gastrointestinal epithelium  Conference Paper
• Molecular and clinical aspects of apoptosis  Academic Article
• Molecular mechanisms of memory formation  Academic Article
• Monoclonal antibody BB9 raised against bone marrow stromal cells identifies a cell-surface glycoprotein expressed by primitive human hemopoietic progenitors  Academic Article
• Mucin-like molecules as modulators of the survival and proliferation of primitive hematopoietic cells  Academic Article
• NADPH oxidase activity is higher in cerebral versus systemic arteries of four animal species: role of Nox2  Academic Article
• NADPH oxidase isoform selective regulation of endothelial cell proliferation and survival  Academic Article
• NOX2β: A Novel Splice Variant of NOX2 That Regulates NADPH Oxidase Activity in Macrophages  Academic Article
• Negative regulation of gp130 signalling mediated through tyrosine-757 is not dependent on the recruitment of SHP2  Academic Article
• New 1-Aryl-3-(4-arylpiperazin-1-yl)propane Derivatives, with Dual Action at 5-HT 1A Serotonin Receptors and Serotonin Transporter, as a New Class of Antidepressants  Academic Article
• New 3-[4-(aryl)piperazin-1-yl]-1-(benzo[b]thiophen-3-yl)propane derivatives with dual action at 5-HT1A serotonin receptors and serotonin transporter as a new class of antidepressants  Academic Article
• Nitric oxide suppresses NADPH oxidase-dependent superoxide production by S-nitrosylation in human endothelial cells  Academic Article
• Nitroxyl (HNO) suppresses vascular Nox2 oxidase activity  Academic Article
• Nox1 upregulates the function of vascular T-type calcium channels following chronic nitric oxide deficit  Academic Article
• Nox2 oxidase activity accounts for the oxidative stress and vasomotor dysfunction in mouse cerebral arteries following ischemic stroke  Academic Article
• PSGL-1-Mediated Adhesion of Human Hematopoietic Progenitors to P-Selectin Results in Suppression of Hematopoiesis  Academic Article
• Peripheral blood is a source of BCR-ABL-negative pre-progenitors in early chronic phase chronic myeloid leukemia  Academic Article
• Phase I Trial of 131I-huA33 in Patients with Advanced Colorectal Carcinoma  Academic Article
• Podoplanin is a component of extracellular vesicles that reprograms cell-derived exosomal proteins and modulates lymphatic vessel formation  Academic Article
• Polymorphisms in Erythrocyte Binding Antigens 140 and 181 Affect Function and Binding but Not Receptor Specificity in Plasmodium falciparum  Academic Article
• Predictive assays for tumor response to single and multiple fractions of hyperthermia.  Academic Article
• Preparation of highly purified human myelin oligodendrocyte glycoprotein in quantities sufficient for encephalitogenicity and immunogenicity studies  Academic Article
• Promoter region methylation does not account for the frequent loss of expression of the Fas gene in colorectal carcinoma  Academic Article
• Rapid and specific targeting of monoclonal antibody A33 to a colon cancer xenograft in nude mice  Academic Article
• Rat macrophages: membrane glycoproteins in differentiation and function  Academic Article
• Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice  Academic Article
• Reducing haziness in white wine by overexpression of Saccharomyces cerevisiae genes YOL155c and YDR055w  Academic Article
• Reduction of cerebral infarct volume by apocynin requires pretreatment and is absent in Nox2-deficient mice  Academic Article
• Regulation of Sialoadhesin Expression on Rat Macrophages Induction by Glucocorticoids and Enhancement by IFN-β, IFN-γ, IL-4, and Lipopolysaccharide  Academic Article
• Relative therapeutic efficacy of ¹²⁵I- and ¹³¹I-labeled monoclonal antibody A33 in a human colon cancer xenograft  Academic Article
• Role of Nox isoforms in angiotensin II-induced oxidative stress and endothelial dysfunction in brain  Academic Article
• Scribble regulates an EMT polarity pathway through modulation of MAPK-ERK signaling to mediate junction formation  Academic Article
• Sheep perforin: identification and expression by γδ T cells from pregnant sheep uterine epithelium  Academic Article
• Sialoadhesin on macrophages: its identification as a lymphocyte adhesion molecule  Academic Article
• Signal Regulatory Protein   Ligation Induces Macrophage Nitric Oxide Production through JAK/STAT- and Phosphatidylinositol 3-Kinase/Rac1/NAPDH Oxidase/H2O2-Dependent Pathways  Academic Article
• Signal-Regulatory Protein  -CD47 Interactions Are Required for the Transmigration of Monocytes Across Cerebral Endothelium  Academic Article
• Signal-regulatory protein is selectively expressed by myeloid and neuronal cells  Academic Article
• Stoichiometry of the Interleukin-6 High Affinity Receptor Complex  Conference Paper
• Store-operated calcium entry remains fully functional in aged mouse skeletal muscle despite a decline in STIM1 protein expression  Academic Article
• Structural basis for the high-affinity interaction of nidogen-1 with immunoglobulin-like domain 3 of perlecan  Academic Article
• TGF-βRII Rescues Development of Small Intestinal Epithelial Cells in Elf3-Deficient Mice  Academic Article
• TLR9 and TLR7/8 activation induces formation of keratic precipitates and giant macrophages in the mouse cornea  Academic Article
• TRAIL and Malignant Glioma  Academic Article
• Targeting cancer cells: Controlling the binding and internalization of antibody-functionalized capsules  Academic Article
• Targeting plasma cells in autoimmune diseases  Academic Article
• Taurine supplementation increases skeletal muscle force production and protects muscle function during and after high-frequency in vitro stimulation  Academic Article
• The Carboxyl-terminal Domains of gp130-related Cytokine Receptors Are Necessary for Suppressing Embryonic Stem Cell Differentiation  Academic Article
• The Complete DNA Sequence of Myxoma Virus  Academic Article
• The IL-6–gp130–STAT3 pathway in hepatocytes triggers liver protection in T cell–mediated liver injury  Academic Article
• The Immunoglobulin-like Module of gp130 Is Required for Signaling by Interleukin-6, but Not by Leukemia Inhibitory Factor  Academic Article
• The N-Terminus of gp130 is Critical for the Formation of the High-Affinity Interleukin-6 Receptor Complex  Academic Article
• The anti-platelet effects of apocynin in mice are not mediated by inhibition of NADPH oxidase activity  Academic Article
• The effect of taurine and beta-alanine supplementation on taurine transporter protein and fatigue resistance in skeletal muscle from mdx mice  Academic Article
• The human A33 antigen is a transmembrane glycoprotein and a novel member of the immunoglobulin superfamily  Academic Article
• The macrophage CD163 surface glycoprotein is an erythroblast adhesion receptor  Academic Article
• The murine A33 antigen is expressed at two distinct sites during development, the ICM of the blastocyst and the intestinal epithelium  Academic Article
• The p35 relative, p49, inhibits mammalian and Drosophila caspases including DRONC and protects against apoptosis  Academic Article
• The role of T/B cell interactions and cytokines in the regulation of human IgE synthesis  Academic Article
• The role of gp130/IL-6 cytokines in the development of pulmonary fibrosis: critical determinants of disease susceptibility and progression?  Academic Article
• The role of the interleukin-6 family of cytokines in inflammatory arthritis and bone turnover  Academic Article
• The threshold of gp130-dependent STAT3 signaling is critical for normal regulation of hematopoiesis  Academic Article
• Transduction of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand into Hematopoietic Cells Leads to Inhibition of Syngeneic Tumor Growth In vivo  Academic Article
• Transgenic expression of CD95 ligand on islet   cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts  Academic Article
• Transition-State Analogue γ-Secretase Inhibitors Stabilize a 900 kDa Presenilin/Nicastrin Complex †  Academic Article
• Two Distinct Populations of Exosomes Are Released from LIM1863 Colon Carcinoma Cell-derived Organoids  Academic Article
• Upregulation of store-operated Ca 2+ entry in dystrophic mdx mouse muscle  Academic Article
• Use of the 5′ -flanking region of the mouse perforin gene to express human Fcγ receptor I in cytotoxic T lymphocytes  Academic Article
• Vesicular Monoamine Transport Inhibitors: Novel Action at Calcium Channels to Prevent Catecholamine Secretion  Academic Article
• Ways around rejection  Academic Article
• gp130-mediated Signal Transduction in Embryonic Stem Cells Involves Activation of Jak and Ras/Mitogen-activated Protein Kinase Pathways  Academic Article