subject area of

• 'Click' assembly of glycoclusters and discovery of a trehalose analogue that retards Aβ40 aggregation and inhibits Aβ40-induced neurotoxicity  Academic Article

• Titania nanotube-based protein delivery system to inhibit cranial bone regeneration in Crouzon model of craniosynostosis

    Academic Article
• A Helicobacter pylori Homolog of Eukaryotic Flotillin is Involved in Cholesterol Accumulation, Epithelial Cell Responses and Host Colonization  Academic Article
• A Microenvironment-Induced Myeloproliferative Syndrome Caused by Retinoic Acid Receptor γ Deficiency  Academic Article
• A Mouse Model of Harlequin Ichthyosis Delineates a Key Role for Abca12 in Lipid Homeostasis  Academic Article
• A Myc-dependent division timer complements a cell-death timer to regulate T cell and B cell responses  Academic Article
• A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production  Academic Article
• A Reduction in selenoprotein S amplifies the inflammatory profile of fast-twitch skeletal muscle in the mdx dystrophic mouse  Academic Article
• A chemical screening approach to identify novel key mediators of erythroid enucleation  Academic Article
• A flow cytometric method for the analysis of macrophages in the vascular wall  Academic Article
• A hypermorphic epithelial beta-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations  Academic Article
• A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense  Academic Article
• A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo  Academic Article
• A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation  Academic Article
• A novel achiral seco-cyclopropylpyrido[e]indolone (CPyI) analog of CC-1065 and the duocarmycins: Synthesis, DNA interactions, in vivo anticancer and anti-parasitic evaluation  Academic Article
• A novel mouse model of atherosclerotic plaque Instability for drug testing and mechanistic/therapeutic discoveries using gene and microRNA expression profiling  Academic Article
• A potent Nrf2 activator, dh404, bolsters antioxidant capacity in glial cells and attenuates ischaemic retinopathy  Academic Article
• A potential link between the c5a receptor 1 and the β1-adrenoreceptor in the mouse heart  Academic Article
• A pro-inflammatory role for Th22 cells in Helicobacter pylori-associated gastritis  Academic Article
• A single-chain antibody-CD39 fusion protein targeting activated platelets protects from cardiac ischaemia/reperfusion injury  Academic Article
• A structurally minimized yet fully active insulin based on cone-snail venom insulin principles  Academic Article
• A33 antigen-deficient mice have defective colonic mucosal repair  Academic Article
• ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling  Academic Article
• AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC  Academic Article
• ALDH Enzyme Expression Is Independent of the Spermatogenic Cycle, and Their Inhibition Causes Misregulation of Murine Spermatogenic Processes  Academic Article
• Abnormalities in structure and function of limb skeletal muscle fibres of dystrophic mdx mice  Academic Article
• Abrogation of cathepsin C by Helicobacter pylori impairs neutrophil activation to promote gastric infection  Academic Article
• Absolute amounts and diffusibility of HSP72, HSP25, and αB-crystallin in fast- and slow-twitch skeletal muscle fibers of rat  Academic Article
• Accumulation of Non-Transferrin-Bound Iron by Neurons, Astrocytes, and Microglia  Academic Article
• Accumulation of serum lipids by vascular smooth muscle cells involves a macropinocytosis-like uptake pathway and is associated with the downregulation of the ATP-binding cassette transporter A1  Academic Article
• Activated MLKL attenuates autophagy following its translocation to intracellular membranes  Academic Article
• Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice  Academic Article
• Activation of Liver X Receptor Decreases Atherosclerosis in Ldlr-/- Mice in the Absence of ATP-Binding Cassette Transporters A1 and G1 in Myeloid Cells  Academic Article
• Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes  Academic Article
• Activin and NADPH-oxidase in preeclampsia: Insights from in vitro and murine studies  Academic Article
• Acute myeloid leukemia requires Hhex to enable PRC2-mediated epigenetic repression ofCdkn2a  Academic Article
• Addition of a Prominent Epitope Affects Influenza A Virus-Specific CD8+T Cell Immunodominance Hierarchies When Antigen Is Limiting  Academic Article
• Adipose Tissue Macrophages Promote Myelopoiesis and Monocytosis in Obesity  Academic Article
• Adipose triacylglycerol lipase deletion alters whole body energy metabolism and impairs exercise performance in mice  Academic Article
• Adult Neural Precursor Cells from the Subventricular Zone Contribute Significantly to Oligodendrocyte Regeneration and Remyelination  Academic Article
• Advanced atherosclerosis is associated with inflammation, vascular dysfunction and oxidative stress, but not hypertension  Academic Article
• Age and energy intake interact to modify cell stress pathways and stroke outcome  Academic Article
• Age-related changes in tissue macrophages precede cardiac functional impairment  Academic Article
• Aldosterone-induced oxidative stress and inflammation in the brain are mediated by the endothelial cell mineralocorticoid receptor  Academic Article
• All Known In Vivo Functions of the Oct-2 Transcription Factor Require the C-Terminal Protein Domain  Academic Article
• Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity  Academic Article
• Alterations in anxiety and social behaviour in Npas4 deficient mice following photochemically-induced focal cortical stroke  Academic Article
• Altered expression of histone and synaptic plasticity associated genes in the hippocampus of streptozotocin-induced diabetic mice  Academic Article
• Altered social cognition in male BDNF heterozygous mice and following chronic methamphetamine exposure  Academic Article
• Alternative cross-priming through CCL17-CCR4-mediated attraction of CTLs toward NKT cell–licensed DCs  Academic Article
• Amino acid transport system L activity in developing mouse ovarian follicles  Academic Article
• An Innovative Triple Immunogold Labeling Method to Investigate the Hemopoietic Stem Cell NicheIn Situ  Academic Article
• An Oxysterol-Binding Protein Family Identified in the Mouse  Academic Article
• An adipoinductive role of inflammation in adipose tissue engineering: Key factors in the early development of engineered soft tissues  Academic Article
• An atypical role for the myeloid receptor Mincle in central nervous system injury  Academic Article
• An exported protein-interacting complex involved in the trafficking of virulence determinants in Plasmodium-infected erythrocytes  Academic Article
• An optimized method for establishing high purity murine CD8+ T cell cultures  Academic Article
• Anakinra reduces blood pressure and renal fibrosis in one kidney/DOCA/salt-induced hypertension  Academic Article
• Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma  Academic Article
• Analyzing the influence of BDNF heterozygosity on spatial memory response to 17 beta-estradiol  Academic Article
• Angiotensin converting enzyme inhibition lowers body weight and improves glucose tolerance in C57BL/6J mice maintained on a high fat diet  Academic Article
• Angiotensin-converting enzyme (ACE) interacts with dopaminergic mechanisms in the brain to modulate prepulse inhibition in mice  Academic Article
• Angiotensin-converting enzyme inhibition reverses diet-induced obesity, insulin resistance and inflammation in C57BL/6J mice  Academic Article
• Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis  Academic Article
• Anti-apoptotic gene Bcl2 is required for stapes development and hearing  Academic Article
• Anti-apoptotic mcl-1 is essential for the development and sustained growth of acute myeloid leukemia  Academic Article
• Anticancer prodrugs of butyric acid and formaldehyde protect against doxorubicin-induced cardiotoxicity  Academic Article
• Antigen-Specific T-Cell Responses to a Recombinant Fowlpox Virus Are Dependent on MyD88 and Interleukin-18 and Independent of Toll-Like Receptor 7 (TLR7)- and TLR9-Mediated Innate Immune Recognition  Academic Article
• Anti‐TIM‐1 Monoclonal Antibody (RMT1‐10) Attenuates Atherosclerosis By Expanding IgM‐producing B1a Cells  Academic Article
• ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice  Academic Article
• Apolipoprotein AI) Promotes Atherosclerosis Regression in Diabetic Mice by Suppressing Myelopoiesis and Plaque Inflammation  Academic Article
• Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome  Academic Article
• Arginase II Knockout Mouse Displays a Hypertensive Phenotype Despite a Decreased Vasoconstrictory Profile  Academic Article
• Aromatase Deficiency Confers Paradoxical Postischemic Cardioprotection  Academic Article
• Association of Regulatory T-Cell Expansion With Progression of Amyotrophic Lateral Sclerosis  Academic Article
• Astrocyte-associated axonal damage in pre-onset stages of experimental autoimmune encephalomyelitis  Academic Article
• Astrocytes retain their antioxidant capacity into advanced old age  Academic Article
• Asymmetric Cell Division of T Cells upon Antigen Presentation Uses Multiple Conserved Mechanisms  Academic Article
• Asymmetric cell division during T cell development controls downstream fate  Academic Article
• Atherosclerosis proceeds independently of thrombin-induced platelet activation in ApoE−/− mice  Academic Article
• Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis  Academic Article
• Autocrine IFN-I inhibits isocitrate dehydrogenase in the TCA cycle of LPS-stimulated macrophages  Academic Article
• Avoidance of self-reactivity results in skewed CTL responses to rare components of synthetic immunogens  Academic Article
• BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis  Academic Article
• BDNF Val66Met Genotype Interacts With a History of Simulated Stress Exposure to Regulate Sensorimotor Gating and Startle Reactivity.  Academic Article
• BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes  Academic Article
• BSE prions propagate as either variant CJD-like or sporadic CJD-like prion strains in transgenic mice expressing human prion protein  Academic Article
• BTB-ZF transcriptional regulator PLZF modifies chromatin to restrain inflammatory signaling programs  Academic Article
• Bax targets mitochondria by distinct mechanisms before or during apoptotic cell death: a requirement for VDAC2 or Bak for efficient Bax apoptotic function  Academic Article
• Bcl-2 Expression Inhibits Liver Carcinogenesis and Delays the Development of Proliferating Foci  Academic Article
• Bcl-2 delays and alters hepatic carcinogenesis induced by transforming growth factor  Academic Article
• Bcl-2–regulated apoptosis and cytochrome c release can occur independently of both caspase-2 and caspase-9  Academic Article
• Bcl10 Mediates Angiotensin II–Induced Cardiac Damage and Electrical Remodeling  Academic Article
• Behavioural phenotype of APPC100.V717F transgenic mice over-expressing a mutant Aβ-bearing fragment is associated with reduced NMDA receptor density  Academic Article
• Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax  Academic Article
• Binding of CD40L to Mac-1's I-Domain Involves the EQLKKSKTL Motif and Mediates Leukocyte Recruitment and Atherosclerosis—But Does Not Affect Immunity and Thrombosis in Mice  Academic Article
• Biochemical and Structural Insights into Doublecortin-like Kinase Domain 1  Academic Article
• Blocking IL-6 trans-signaling prevents high-fat diet-induced adipose tissue macrophage recruitment but does not improve insulin resistance  Academic Article
• Blocking LIF action in the uterus by using a PEGylated antagonist prevents implantation: A nonhormonal contraceptive strategy  Academic Article
• Brain infarct volume after permanent focal ischemia is not dependent on Nox2 expression  Academic Article
• Brain-derived neurotrophic factor haploinsufficiency impairs high-frequency cortical oscillations in mice  Academic Article
• C-Rel Regulates Interleukin 12 P70 Expression in Cd8+ Dendritic Cells by Specifically Inducing p35 Gene Transcription  Academic Article
• C-terminal peptides modelling constitutive PrPC processing demonstrate ameliorated toxicity predisposition consequent to α-cleavage  Academic Article
• C5a Receptor (CD88) Inhibition Improves Hypothermia-Induced Neuroprotection in an In Vitro Ischemic Model  Academic Article
• C9ORF72 expression and cellular localization over mouse development  Academic Article
• CALORIE RESTRICTION INCREASES LIPOPOLYSACCHARIDE-INDUCED NEUROPEPTIDE Y IMMUNOLABELING AND REDUCES MICROGLIAL CELL AREA IN THE ARCUATE HYPOTHALAMIC NUCLEUS  Academic Article
• CCK2 receptor nullification attenuates lipopolysaccharide-induced sickness behavior  Academic Article
• CCR6 (CC chemokine receptor 6) is essential for the migration of detrimental natural interleukin-17-producing γδ T cells in stroke  Academic Article
• CD11b immunophenotyping identifies inflammatory profiles in the mouse and human lungs  Academic Article
• CD151, a novel host factor of nuclear export signaling in influenza virus infection  Academic Article
• CD4+T Cells Acting Independently of Antibody Contribute to Protective Immunity toPlasmodiumchabaudiInfection After Apical Membrane Antigen 1 Immunization  Academic Article
• CD40 Ligand Mediates Inflammation Independently of CD40 by Interaction With Mac-1  Academic Article
• CD40L Deficiency Attenuates Diet-Induced Adipose Tissue Inflammation by Impairing Immune Cell Accumulation and Production of Pathogenic IgG-Antibodies  Academic Article
• CIS is a potent checkpoint in NK cell–mediated tumor immunity  Academic Article
• CNTF Gene Therapy Confers Lifelong Neuroprotection in a Mouse Model of Human Retinitis Pigmentosa  Academic Article
• CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK  Academic Article
• CREB-binding protein (CBP) regulates β-adrenoceptor (β-AR)−mediated apoptosis  Academic Article
• CREB1 and CREB-binding protein in striatal medium spiny neurons regulate behavioural responses to psychostimulants  Academic Article
• CSF-1 receptor signalling from endosomes mediates the sustained activation of Erk1/2 and Akt in macrophages  Academic Article
• Ca2+-dependent proteolysis of junctophilin-1 and junctophilin-2 in skeletal and cardiac muscle  Academic Article
• Calcium signaling is required for erythroid enucleation  Academic Article
• Calorie restriction attenuates LPS-induced sickness behavior and shifts hypothalamic signaling pathways to an anti-inflammatory bias  Academic Article
• Calorie restriction attenuates lipopolysaccharide (LPS)-induced microglial activation in discrete regions of the hypothalamus and the subfornical organ  Academic Article
• Calsenilin contributes to neuronal cell death in ischemic stroke  Academic Article
• Cancer cell CCL5 mediates bone marrow independent angiogenesis in breast cancer  Academic Article
• Cardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair  Academic Article
• Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9  Academic Article
• Ceasing exercise induces depression-like, anxiety-like, and impaired cognitive-like behaviours and altered hippocampal gene expression  Academic Article
• Celastrol, a Triterpene Extracted From Tripterygium wilfordii Hook F, Inhibits Platelet Activation  Academic Article
• Cell Cycle-Related Acquisition of Cytotoxic Mediators Defines the Progressive Differentiation to Effector Status for Virus-Specific CD8+ T Cells  Academic Article
• Cell division autoantigen 1 enhances signaling and the profibrotic effects of transforming growth factor-β in diabetic nephropathy  Academic Article
• Cell surface expression of a peptide encoded by the unrearranged TCR-Vβ8.2 gene  Academic Article
• Cellular inhibitor of apoptosis proteins prevent clearance of hepatitis B virus  Academic Article
• Chain-specific antibodies for laminin-511  Academic Article
• Changes in Cerebral Arteries and Parenchymal Arterioles With Aging: Role of Rho Kinase 2 and Impact of Genetic Background  Academic Article
• Changes in plasma membrane Ca-ATPase and stromal interacting molecule 1 expression levels for Ca2+ signaling in dystrophic mdx mouse muscle  Academic Article
• Changes in the levels of enzymes which modulate the antioxidant balance occur during aging and correlate with cellular damage  Academic Article
• Characterisation of mice lacking all functional isoforms of the pro-survival BCL-2 family member A1 reveals minor defects in the haematopoietic compartment  Academic Article
• Characterisation of the novel apoptotic and therapeutic activities of the histone deacetylase inhibitor romidepsin  Academic Article
• Characterization of Blimp-1 function in effector regulatory T cells  Academic Article
• Characterization of Two Homologous Disulfide Bond Systems Involved in Virulence Factor Biogenesis in Uropathogenic Escherichia coli CFT073  Academic Article
• Characterization of a Dominant Cone Degeneration in a Green Fluorescent Protein–Reporter Mouse with Disruption of Loci Associated with Human Dominant Retinal Dystrophy  Academic Article
• Characterization of a Serine Protease Homologous to House Dust Mite Group 3 Allergens from the Scabies Mite Sarcoptes scabiei  Academic Article
• Characterization of the phospholemman knockout mouse heart: depressed left ventricular function with increased Na-K-ATPase activity  Academic Article
• Characterization oflacZ-expressing cells in the gut of embryonic and adultD?H-nlacZ mice  Academic Article
• Characterizing the Spermatogonial Response to Retinoic Acid During the Onset of Spermatogenesis and Following Synchronization in the Neonatal Mouse Testis  Academic Article
• Chemical Attenuation of Plasmodium berghei Sporozoites Induces Sterile Immunity in Mice  Academic Article
• Chemical chaperone TUDCA prevents apoptosis and improves survival during polymicrobial sepsis in mice  Academic Article
• Chemokine-related gene expression in the brain following ischemic stroke: No role for CXCR2 in outcome  Academic Article
• Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis  Academic Article
• Chronic Helicobacter pylori Infection Does Not Significantly Alter the Microbiota of the Murine Stomach  Academic Article
• Chronic angiotensin IV treatment reverses endothelial dysfunction in ApoE-deficient mice  Academic Article
• Chronic mevastatin modulates receptor-dependent vascular contraction in eNOS-deficient mice  Academic Article
• Ciliary Neurotrophic Factor Stimulates Muscle Glucose Uptake by a PI3-Kinase-Dependent Pathway That Is Impaired With Obesity  Academic Article
• Class II restriction in mice to the malaria candidate vaccine ring infected erythrocyte surface antigen (RESA) as synthetic peptides or as expressed in recombinant vaccinia  Academic Article
• Clozapine reverses schizophrenia-related behaviours in the metabotropic glutamate receptor 5 knockout mouse: association with N-methyl-d-aspartic acid receptor up-regulation  Academic Article
• Coenzyme Q10 attenuates diastolic dysfunction, cardiomyocyte hypertrophy and cardiac fibrosis in the db/db mouse model of type 2 diabetes  Academic Article
• Coinhibitory suppression of T cell activation by CD40 protects against obesity and adipose tissue inflammation in mice  Academic Article
• Collaborative Regulation of LRG1 by TGF-beta 1 and PPAR-beta/delta Modulates Chronic Pressure Overload-Induced Cardiac Fibrosis  Academic Article
• Combination therapy of mesenchymal stem cells and serelaxin effectively attenuates renal fibrosis in obstructive nephropathy  Academic Article
• Combination therapy with low-dose IVIG and a C1-esterase inhibitor ameliorates brain damage and functional deficits in experimental ischemic stroke  Academic Article
• Comparative analysis reveals a role for TGF-β in shaping the residency-related transcriptional signature in tissue-resident memory CD8+ T cells  Academic Article
• Compartment resolved reference proteome map from highly purified naive, activated, effector, and memory CD8(+) murine immune cells  Academic Article
• Conformation-Specific Blockade of the Integrin GPIIb/IIIa  Academic Article
• Constitutive Activation of the Src Family Kinase Hck Results in Spontaneous Pulmonary Inflammation and an Enhanced Innate Immune Response  Academic Article
• Continuous testosterone administration prevents skeletal muscle atrophy and enhances resistance to fatigue in orchidectomized male mice  Academic Article
• Contributions of LFA-1 and Mac-1 to brain injury and microvascular dysfunction induced by transient middle cerebral artery occlusion  Academic Article
• Cooperative and independent roles of the Drp1 adaptors Mff, MiD49 and MiD51 in mitochondrial fission  Academic Article
• Cu/Zn superoxide dismutase mRNA and enzyme activity, and susceptibility to lipid peroxidation, increases with aging in murine brains  Academic Article
• Cu/Zn-superoxide dismutase and glutathione peroxidase during aging  Academic Article
• Cutting Edge: Recombinant Adenoviruses Induce CD8 T Cell Responses to an Inserted Protein Whose Expression Is Limited to Nonimmune Cells  Academic Article
• Cytoskeletal Tropomyosin Tm5NM1 Is Required for Normal Excitation–Contraction Coupling in Skeletal Muscle  Academic Article
• Cytosolic PTEN-induced putative kinase 1 is stabilized by the NF-κB pathway and promotes non-selective mitophagy  Academic Article
• Cytotoxic T lymphocyte–induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis  Academic Article
• DNA-binding-dependent androgen receptor signaling contributes to gender differences and has physiological actions in males and females  Academic Article
• Decreased IL-17RB expression impairs CD11b(+)CD11c(-) myeloid cell accumulation in gastric mucosa and host defense during the early-phase of Helicobacter pylori infection  Academic Article
• Decreased anti-regenerative effects after spinal cord injury in spry4−/− mice  Academic Article
• Deficiency of ATP-Binding Cassette Transporter B6 in Megakaryocyte Progenitors Accelerates Atherosclerosis in Mice  Academic Article
• Deficiency of selenoprotein S, an endoplasmic reticulum resident oxidoreductase, impairs the contractile function of fast twitch hindlimb muscles  Academic Article
• Defining the role of cytoskeletal components in the formation of apoptopodia and apoptotic bodies during apoptosis  Academic Article
• Defining the target specificity of ABT-737 and synergistic antitumor activities in combination with histone deacetylase inhibitors  Academic Article
• Delayed targeting of CD39 to activated platelet GPIIb/IIIa via a single-chain antibody: breaking the link between antithrombotic potency and bleeding?  Academic Article
• Delayed-type hypersensitivity to liver F antigen in the mouse  Academic Article
• Deletion of Skeletal Muscle SOCS3 Prevents Insulin Resistance in Obesity  Academic Article
• Deletion of Trim28 in committed adipocytes promotes obesity but preserves glucose tolerance  Academic Article
• Deletion of cIAP1 and cIAP2 in murine B lymphocytes constitutively activates cell survival pathways and inactivates the germinal center response  Academic Article
• Demonstration of elevated levels of active cathepsin S in dextran sulfate sodium colitis using a new activatable probe  Academic Article
• Derivative of Bardoxolone Methyl, dh404, in an Inverse Dose-Dependent Manner Lessens Diabetes-Associated Atherosclerosis and Improves Diabetic Kidney Disease  Academic Article
• Destruction of tumor vasculature and abated tumor growth upon VEGF blockade is driven by proapoptotic protein Bim in endothelial cells  Academic Article
• Detection of activated platelets in a mouse model of carotid artery thrombosis with 18F-labeled single-chain antibodies  Academic Article
• Developing a quantitative in vivo tissue reconstitution assay to assess the relative potency of candidate populations of mouse oesophageal epithelial cells  Academic Article
• Development of monoclonal anti-PDGF-CC antibodies as tools for investigating human tissue expression and for blocking PDGF-CC induced PDGFRα signalling in vivo  Academic Article
• Development of satellite glia in mouse sympathetic ganglia: GDNF and GFRα1 are not essential  Academic Article
• Developmental impact of a familial GABAAreceptor epilepsy mutation  Academic Article
• Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons  Academic Article
• Diastolic dysfunction is more apparent in STZ-induced diabetic female mice, despite less pronounced hyperglycemia  Academic Article
• Diet-induced vitamin D deficiency has no effect on acute post-stroke outcomes in young male mice  Academic Article
• Dietary repletion with ω3 fatty acid or with COX inhibition reverses cognitive effects in F3 ω3 fatty-acid-deficient mice  Academic Article
• Dietary resveratrol supplementation normalizes gene expression in the hippocampus of streptozotocin-induced diabetic C57Bl/6 mice  Academic Article
• Dietary supplementation with resveratrol and/or docosahexaenoic acid alters hippocampal gene expression in adult C57Bl/6 mice  Academic Article
• Differential Effects of CpG DNA on IFN-β Induction and STAT1 Activation in Murine Macrophages versus Dendritic Cells: Alternatively Activated STAT1 Negatively Regulates TLR Signaling in Macrophages  Academic Article
• Differential Regulation of Gastric Tumor Growth by Cytokines That Signal Exclusively Through the Coreceptor gp130  Academic Article
• Differential Regulation of Simultaneous Antitumor and Alloreactive CD8+ T-Cell Responses in the Same Host by Rapamycin  Academic Article
• Differential anxiety-like responses in NOD/ShiLtJ and C57BL/6J mice following experimental autoimmune encephalomyelitis induction and oral gavage  Academic Article
• Differential brain and spinal cord cytokine and BDNF levels in experimental autoimmune encephalomyelitis are modulated by prior and regular exercise  Academic Article
• Differential effect of amphetamine on c-fos expression in female aromatase knockout (ArKO) mice compared to wildtype controls  Academic Article
• Differential expansion of T central memory precursor and effector subsets is regulated by division speed  Academic Article
• Direct AT(2) receptor stimulation is athero-protective and stabilizes plaque in Apolipoprotein E-deficient mice  Academic Article
• Discriminating the earliest stages of mammary carcinoma using myoepithelial and proliferative markers  Academic Article
• Disruption of Mammalian Target of Rapamycin Complex 1 in Macrophages Decreases Chemokine Gene Expression and Atherosclerosis  Academic Article
• Disruption of prepulse inhibition by 3,4-methylenedioxymethamphetamine (MDMA): comparison between male and female wild-type and 5-HT1A receptor knockout mice  Academic Article
• Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade  Academic Article
• Distinct contributions of hyperglycemia and high-fat feeding in metabolic syndrome-induced neuroinflammation  Academic Article
• Diverging impact of cell fate determinants Scrib and Llgl1 on adhesion and migration of hematopoietic stem cells  Academic Article
• Does lack of glutathione peroxidase 1 gene expression exacerbate lung injury induced by neonatal hyperoxia in mice?  Academic Article
• Dopaminergic activity and behaviour in SOCS2 transgenic mice: Revealing a potential drug target for schizophrenia  Academic Article
• Dual role of Src kinase in governing neuronal survival  Academic Article
• Dual targeting improves capture of ultrasound microbubbles towards activated platelets but yields no additional benefit for imaging of arterial thrombosis  Academic Article
• Dual-contrast molecular imaging allows noninvasive characterization of myocardial ischemia/reperfusion injury after coronary vessel occlusion in mice by magnetic resonance imaging  Academic Article
• Dynamic quantification of MHC class I–peptide presentation to CD8+ T cells via intracellular cytokine staining  Academic Article
• Dysferlin-deficiency has greater impact on function of slow muscles, compared with fast, in aged BLAJ mice  Academic Article
• Dysregulation of the complement cascade in the hSOD1G93A transgenic mouse model of amyotrophic lateral sclerosis  Academic Article
• EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival  Academic Article
• ERp57 is protective against mutant SOD1-induced cellular pathology in amyotrophic lateral sclerosis  Academic Article
• Early functional muscle regeneration after myotoxic injury in mice is unaffected by nNOS absence  Academic Article
• Early glial responses in murine models of multiple sclerosis  Academic Article
• Early precursor T cells establish and propagate T cell exhaustion in chronic infection  Academic Article
• Ebselen by modulating oxidative stress improves hypoxia-induced macroglial Müller cell and vascular injury in the retina  Academic Article
• Effect of Dystrophin Deficiency on Selected Intrinsic Laryngeal Muscles of the mdx Mouse  Academic Article
• Effect of a Broad-Specificity Chemokine-Binding Protein on Brain Leukocyte Infiltration and Infarct Development  Academic Article
• Effect of a Selective Mas Receptor Agonist in Cerebral Ischemia In Vitro and In Vivo  Academic Article
• Effect of adolescent androgen manipulation on psychosis-like behaviour in adulthood in BDNF heterozygous and control mice  Academic Article
• Effect of adrenalectomy and corticosterone replacement on prepulse inhibition and locomotor activity in mice  Academic Article
• Effect of fingolimod on oligodendrocyte maturation under prolonged cerebral hypoperfusion  Academic Article
• Effect of immunosuppressive agents on hepatocyte apoptosis post-liver transplantation  Academic Article
• Effect ofGdnf haploinsufficiency on rate of migration and number of enteric neural crest-derived cells  Academic Article
• Effector Regulatory T Cell Differentiation and Immune Homeostasis Depend on the Transcription Factor Myb  Academic Article
• Effects of Centrally Administered Etanercept on Behavior, Microglia, and Astrocytes in Mice Following a Peripheral Immune Challenge  Academic Article
• Effects of NGF, NT-3 and GDNF family members on neurite outgrowth and migration from pelvic ganglia from embryonic and newborn mice  Academic Article
• Effects of Npas4 deficiency on anxiety, depression-like, cognition and sociability behaviour  Academic Article
• Effects of beta-hydroxybutyrate administration on MK-801-induced schizophrenia-like behaviour in mice  Academic Article
• Effects of chemokine receptor signalling on cognition-like, emotion-like and sociability behaviours of CCR6 and CCR7 knockout mice  Academic Article
• Effects of different regions of the developing gut on the migration of enteric neural crest-derived cells: A role for Sema3A, but not Sema3F  Academic Article
• Effects of exercise training and RhoA/ROCK inhibition on plaque in ApoE−/− mice  Academic Article
• Effects of lipopolysaccharide on glial phenotype and activity of glutamate transporters: Evidence for delayed up-regulation and redistribution of GLT-1  Academic Article
• Efficient Distribution of a Novel Zirconium-89 Labeled Anti-cd20 Antibody Following Subcutaneous and Intravenous Administration in Control and Experimental Autoimmune Encephalomyelitis-Variant Mice  Academic Article
• Electroporation and commercial liposomes efficiently deliver soluble protein into the MHC class I presentation pathway  Academic Article
• Electroporation of Antigen-Presenting Cells for T-Cell Recognition and Cytotoxic T-Lymphocyte Priming  Academic Article
• Elevated GLUT4 and glycogenin protein abundance correspond to increased glycogen content in the soleus muscle of mdx mice with no benefit associated with taurine supplementation  Academic Article
• Eliminating hepatitis B by antagonizing cellular inhibitors of apoptosis  Academic Article
• Endogenous bcl-2 is not required for the development of Eμ-myc–induced B-cell lymphoma  Academic Article
• Endothelial PPARγ (Peroxisome Proliferator–Activated Receptor-γ) Is Essential for Preventing Endothelial Dysfunction With Aging  Academic Article
• Enhanced Acetaminophen Hepatotoxicity in Transgenic Mice Overexpressing BCL-2  Academic Article
• Enhanced Analysis of the Mouse Plasma Proteome Using Cysteine-Containing Tryptic Glycopeptides  Academic Article
• Enhanced Uterine Artery Stiffness in Aged Pregnant Relaxin Mutant Mice Is Reversed with Exogenous Relaxin Treatment1  Academic Article
• Enhanced effect of dopaminergic stimulation on prepulse inhibition in mice deficient in the alpha subunit of Gz  Academic Article
• Enhanced effects of amphetamine but reduced effects of the hallucinogen, 5-MeO-DMT, on locomotor activity in 5-HT1A receptor knockout mice: Implications for schizophrenia  Academic Article
• Enhanced lithium-induced brain recovery following cranial irradiation is not impeded by inflammation  Academic Article
• Enhanced phosphoinositide 3-kinase(p110α) activity prevents diabetes-induced cardiomyopathy and superoxide generation in a mouse model of diabetes  Academic Article
• Ensuring animal welfare while meeting scientific aims using a murine pneumonia model of septic shock  Academic Article
• Environmental Enrichment Ameliorates Behavioral Impairments Modeling Schizophrenia in Mice Lacking Metabotropic Glutamate Receptor 5  Academic Article
• Environmental sensing by mature B cells is controlled by the transcription factors PU.1 and SpiB  Academic Article
• Enzymatic Single-Chain Antibody Tagging  Academic Article
• Ergot alkaloid mycotoxins: physiological effects, metabolism and distribution of the residual toxin in mice  Academic Article
• Evidence That Ly6C(hi) Monocytes Are Protective in Acute Ischemic Stroke by Promoting M2 Macrophage Polarization  Academic Article
• Evidence That the Angiotensin IV (AT4) Receptor Is the Enzyme Insulin-regulated Aminopeptidase  Academic Article
• Evidence for a detrimental role of TLR8 in ischemic stroke  Academic Article
• Evidence for prion protein expression in enteroglial cells of the myenteric plexus of mouse intestine  Academic Article
• Evidence of CCR2-independent transmigration of Ly6C(hi) monocytes into the brain after permanent cerebral ischemia in mice  Academic Article
• Evidence of Platelet Activation at Medically Used Hypothermia and Mechanistic Data Indicating ADP as a Key Mediator and Therapeutic Target  Academic Article
• Evidence that NLRC4 inflammasome mediates apoptotic and pyroptotic microglial death following ischemic stroke  Academic Article
• Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism  Academic Article
• Evidence that collaboration between HIF-1α and Notch-1 promotes neuronal cell death in ischemic stroke  Academic Article
• Evidence that nitric oxide inhibits vascular inflammation and superoxide production via a p47phox-dependent mechanism in mice  Academic Article
• Evidence that γ-secretase-mediated notch signaling induces neuronal cell death via the nuclear factor-κB-Bcl-2-interacting mediator of cell death pathway in ischemic stroke  Academic Article
• Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells  Academic Article
• Experimental and human evidence for Lipocalin‐2 (Neutrophil Gelatinase‐Associated Lipocalin [NGAL]) in the development of cardiac hypertrophy and heart failure  Academic Article
• Experimental autoimmune encephalomyelitis (EAE) IN C57Bl/6 mice is not associated with astrogliosis  Academic Article
• Experimental in vivo sepsis models to monitor immune cell apoptosis and survival in laboratory mice  Chapter
• Exploring the role of 5-HT1A receptors in the regulation of prepulse inhibition in mice: Implications for cross-species comparisons  Academic Article
• Expression Patterns and Roles of Periostin During Kidney and Ureter Development  Academic Article
• Expression of the integrin $alpha;4$beta;1 on melanoma cells can inhibit the invasive stage of metastasis formation  Academic Article
• Extensive phenotyping of two ARX polyalanine expansion mutation mouse models that span clinical spectrum of intellectual disability and epilepsy  Academic Article
• Extrinsically derived TNF is primarily responsible for limiting antiviral CD8+ T cell response magnitude  Academic Article
• FOXC1 is enriched in the mammary luminal progenitor population, but Is not necessary for mouse mammary ductal morphogenesis  Academic Article
• Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time  Academic Article
• Fatal Hepatitis Mediated by Tumor Necrosis Factor TNFα Requires Caspase-8 and Involves the BH3-Only Proteins Bid and Bim  Academic Article
• Fgf2 improves functional recovery-decreasing gliosis and increasing radial glia and neural progenitor cells after spinal cord injury  Academic Article
• Foxp1 is indispensable for ductal morphogenesis and controls the exit of mammary stem cells from quiescence  Academic Article
• Frizzled7 Functions as a Wnt Receptor in Intestinal Epithelial Lgr5+ Stem Cells  Academic Article
• Fructose diet treatment in mice induces fundamental disturbance of cardiomyocyte Ca2+ handling and myofilament responsiveness  Academic Article
• Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer  Academic Article
• Functional and structural characterization of P40, a mouse glycoprotein with T-cell growth factor activity.  Academic Article
• Functional role of soluble receptor for advanced glycation end products in stroke  Academic Article
• G-CSF receptor blockade ameliorates arthritic pain and disease  Academic Article
• Gambogic amide, a selective TrkA agonist, does not improve outcomes from traumatic brain injury in mice  Academic Article
• Gender Influences Cerebral Vascular Responses to Angiotensin II Through Nox2-Derived Reactive Oxygen Species  Academic Article
• Gene dysregulation is restored in the Parkinson's disease MPTP neurotoxic mice model upon treatment of the therapeutic drug Cu-II(atsm)  Academic Article
• Gene expression profiling of intestinal epithelial cell maturation along the crypt-villus axis  Academic Article
• Generation and Analysis of Siah2 Mutant Mice  Academic Article
• Generation of an inducible mouse model to reversibly silence Stat3  Academic Article
• Generic construction of single component particles that elicit humoural and cellular immune responses without the need for adjuvants  Academic Article
• Genetic Dissection of Differential Signaling Threshold Requirements for the Wnt/β-Catenin Pathway In Vivo  Academic Article
• Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis  Academic Article
• Genetic reduction of the extracellular matrix protein versican attenuates inflammatory cell infiltration and improves contractile function in dystrophic mdx diaphragm muscles  Academic Article
• Genome-Wide ENU Mutagenesis in Combination with High Density SNP Analysis and Exome Sequencing Provides Rapid Identification of Novel Mouse Models of Developmental Disease  Academic Article
• Genomic organisation and nervous system expression of radial spoke protein 3  Academic Article
• Glucocorticoids Improve Myogenic Differentiation In Vitro by Suppressing the Synthesis of Versican, a Transitional Matrix Protein Overexpressed in Dystrophic Skeletal Muscles  Academic Article
• Glucose uptake during contraction in isolated skeletal muscles from neuronal nitric oxide synthase mu knockout mice  Academic Article
• Glutathione depletion in the brain disrupts short-term spatial memory in the Y-maze in rats and mice  Academic Article
• Glycoprotein A33 deficiency: A new mouse model of impaired intestinal epithelial barrier function and inflammatory disease  Academic Article
• Gp130-dependent astrocytic survival is critical for the control of autoimmune central nervous system inflammation  Academic Article
• Granulocyte colony stimulating factor expands hematopoietic stem cells within the central but not endosteal bone marrow region  Academic Article
• Granulocyte/macrophage colony-stimulating factor from mouse lung conditioned medium. Purification of multiple forms and radioiodination  Academic Article
• Granzyme M has a critical role in providing innate immune protection in ulcerative colitis  Academic Article
• HMG-CoA reductase promotes protein prenylation and therefore is indispensible for T-cell survival  Academic Article
• HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi  Academic Article
• HOIP deficiency causes embryonic lethality by aberrant TNFR1-mediated endothelial cell death  Academic Article
• Heat-Aggregated Noninfectious Influenza Virus Induces a More Balanced CD8+-T-Lymphocyte Immunodominance Hierarchy Than Infectious Virus  Academic Article
• Helicobacter pylori VacA suppresses Lactobacillus acidophilus-induced interferon beta signaling in macrophages via alterations in the endocytic pathway  Academic Article
• Hematopoietic abnormalities in mice deficient in gp130-mediated STAT signaling  Academic Article
• Hemopoietic Stem Cells with Higher Hemopoietic Potential Reside at the Bone Marrow Endosteum  Academic Article
• Hepatitis C virus-induced hepatocyte cell death and protection by inhibition of apoptosis  Academic Article
• Hepatitis C-induced hepatocyte apoptosis following liver transplantation is enhanced by immunosuppressive agents  Academic Article
• Heterogeneity of Effector Phenotype for Acute Phase and Memory Influenza A Virus-Specific CTL  Academic Article
• Heterogeneous Impact of ROCK2 on Carotid and Cerebrovascular Function  Academic Article
• Hhex Regulates Hematopoietic Stem Cell Self-Renewal and Stress Hematopoiesis via Repression of Cdkn2a  Academic Article
• High salt reduces the activation of IL-4– and IL-13–stimulated macrophages  Academic Article
• High-fructose diet elevates myocardial superoxide generation in mice in the absence of cardiac hypertrophy  Academic Article
• Hippocampal NMDA receptor subunit expression and watermaze learning in estrogen deficient female mice  Academic Article
• Histidine, cystine, glutamine, and threonine collectively protect astrocytes from the toxicity of zinc  Academic Article
• Hoxb8 regulates expression of microRNAs to control cell death and differentiation  Academic Article
• Human Relaxin Gene 3 (H3) and the Equivalent Mouse Relaxin (M3) Gene  Academic Article
• Hyaluronan is synthesized by primitive hemopoietic cells, participates in their lodgment at the endosteum following transplantation, and is involved in the regulation of their proliferation and differentiation in vitro  Academic Article
• Hypercholesterolemia and reduced HDL-C promote hematopoietic stem cell proliferation and monocytosis: Studies in mice and FH children  Academic Article
• Hyperglycemia Promotes Myelopoiesis and Impairs the Resolution of Atherosclerosis  Academic Article
• ICAM-1-dependent pathways regulate colonic eosinophilic inflammation  Academic Article
• IL-10-induced gp130 expression in mouse mast cells permits IL-6 trans-signaling  Academic Article
• IL-33 modulates inflammatory brain injury but exacerbates systemic immunosuppression following ischemic stroke  Academic Article
• IL-6 mediates the susceptibility of glycoprotein 130 hypermorphs to Toxoplasma gondii  Academic Article
• Identification of Candidate Murine Esophageal Stem Cells Using a Combination of Cell Kinetic Studies and Cell Surface Markers  Academic Article
• Identification of an Xiap-Like Pseudogene on Mouse Chromosome 7  Academic Article
• Identification of an activation site in Bak and mitochondrial Bax triggered by antibodies  Academic Article
• Identification of the 70kD Heat Shock Cognate Protein (Hsc70) and α-Actinin-1 as Novel Phosphotyrosine-Containing Proteins in T Lymphocytes  Academic Article
• Illumina WG-6 BeadChip strips should be normalized separately  Academic Article
• Immortalized murine striatal neuronal cell lines expressing dopamine receptors and cholinergic properties  Academic Article
• Immune cell infiltration in malignant middle cerebral artery infarction: comparison with transient cerebral ischemia  Academic Article
• Immunization with a heat-killed preparation of the environmental bacterium Mycobacterium vaccae promotes stress resilience in mice  Academic Article
• Immunologic competence of B cells subjected to constitutive c-myc oncogene expression in immunoglobulin heavy chain enhancer myc transgenic mice  Academic Article
• Immunoproteasomes Shape Immunodominance Hierarchies of Antiviral Cd8+ T Cells at the Levels of T Cell Repertoire and Presentation of Viral Antigens  Academic Article
• Immunotherapy of Cytotoxic T Cell–resistant Tumors by T Helper 2 Cells  Academic Article
• Impact of conditional deletion of the pro-apoptotic BCL-2 family member BIM in mice  Academic Article
• Impaired exercise performance is independent of inflammation and cellular stress following genetic reduction or deletion of selenoprotein S  Academic Article
• Impaired muscle function in a mouse surgical model of post-traumatic osteoarthritis  Academic Article
• Impaired skeletal muscle development and function in male, but not female, genomic androgen receptor knockout mice  Academic Article
• Impaired spatial reference memory in aromatase-deficient (ArKO) mice  Academic Article
• Implication of coronin 7 in body weight regulation in humans, mice and flies  Academic Article
• Importance of Animal Models in Schizophrenia Research  Academic Article
• Improved Detection of Regional Melanoma Metastasis Using 18F-6-Fluoro-N-[2-(Diethylamino)Ethyl] Pyridine-3-Carboxamide, a Melanin-Specific PET Probe, by Perilesional Administration  Academic Article
• In vivo growth of a murine lymphoma cell line alters regulation of expression of HSP72.  Academic Article
• Increased Antigen Specific T Cell Numbers in the Absence of Altered Migration or Division Rates as a Result of Mucosal Cholera Toxin Administration  Academic Article
• Increased Tolerance to Endotoxin by Granulocyte-Macrophage Colony-Stimulating Factor-Deficient Mice  Academic Article
• Increased superoxide production and altered nitric oxide-mediated relaxation in the aorta of young but not old male relaxin-deficient mice  Academic Article
• Increasing Viral Dose Causes a Reversal in CD8+T Cell Immunodominance during Primary Influenza Infection due to Differences in Antigen Presentation, T Cell Avidity, and Precursor Numbers  Academic Article
• Increasing intracellular bioavailable copper selectively targets prostate cancer cells  Academic Article
• Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt-induced hypertension in mice  Academic Article
• Inflammasome adaptor ASC suppresses apoptosis of gastric cancer cells by an IL18-mediated inflammation-independent mechanism  Academic Article
• Inflammation, but not recruitment, of adipose tissue macrophages requires signalling through Mac-1 (CD11b/CD18) in diet-induced obesity (DIO)  Academic Article
• Influenza A Infection Enhances Cross-Priming of CD8+T Cells to Cell-Associated Antigens in a TLR7- and Type I IFN-Dependent Fashion  Academic Article
• Inhibition and Genetic Ablation of the B7/CD28 T-Cell Costimulation Axis Prevents Experimental Hypertension  Academic Article
• Inhibition of Drp1 ameliorates synaptic depression, Aβ deposition, and cognitive impairment in an alzheimer’s disease model  Academic Article
• Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression  Academic Article
• Inhibition of Notch signalling ameliorates experimental inflammatory arthritis  Academic Article
• Inhibition of Notch1 induces population and suppressive activity of regulatory T cell in inflammatory arthritis  Academic Article
• Inhibition of Nox2 Oxidase Activity Ameliorates Influenza A Virus-Induced Lung Inflammation  Conference Paper
• Inhibition of miR-154 protects against cardiac dysfunction and fibrosis in a mouse model of pressure overload  Academic Article
• Inhibition of the all-trans Retinoic Acid (atRA) Hydroxylases CYP26A1 and CYP26B1 Results in Dynamic, Tissue-Specific Changes in Endogenous atRA Signaling  Academic Article
• Inhibitor of apoptosis protein-1 regulates tumor necrosis factor-mediated destruction of intestinal epithelial cells  Academic Article
• Inhibitory Effects of Cytomegalovirus Proteins US2 and US11 Point to Contributions from Direct Priming and Cross-Priming in Induction of Vaccinia Virus-Specific CD8+ T Cells  Academic Article
• Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells  Academic Article
• Insertional mutagenesis inducing hypomyelination in transgenic mice  Academic Article
• Interaction of Brain-Derived Neurotrophic Factor Val66Met genotype and history of stress in regulation of prepulse inhibition in mice  Academic Article
• Interaction of corticosterone and nicotine in regulation of prepulse inhibition in mice  Academic Article
• Interaction of glutathione depletion and psychotropic drug treatment in prepulse inhibition in rats and mice  Academic Article
• Interaction of interleukin-6, tumour necrosis factor and interleukin-1 during Listeria infection  Academic Article
• Interaction of reelin and stress on immobility in the forced swim test but not dopamine-mediated locomotor hyperactivity or prepulse inhibition disruption: Relevance to psychotic and mood disorders  Academic Article
• Interferon-  Protects the Female Reproductive Tract from Viral and Bacterial Infection  Academic Article
• Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically  Academic Article
• Interleukin-3/Granulocyte Macrophage Colony-Stimulating Factor Receptor Promotes Stem Cell Expansion, Monocytosis, and Atheroma Macrophage Burden in Mice With Hematopoietic ApoE Deficiency  Academic Article
• Interleukin-6 trans-signaling exacerbates inflammation and renal pathology in lupus-prone mice  Academic Article
• Intermittent fasting attenuates increases in neurogenesis after ischemia and reperfusion and improves recovery  Academic Article
• Intermittent fasting attenuates inflammasome activity in ischemic stroke  Academic Article
• Intermittent fasting increases adult hippocampal neurogenesis  Academic Article
• Intermittent fasting promotes prolonged associative interactions during synaptic tagging/capture by altering the metaplastic properties of the CA1 hippocampal neurons  Academic Article
• Intermittent hypoxia induces a metastatic phenotype in breast cancer  Academic Article
• Interruption of classic CD40L-CD40 signalling but not of the novel CD40L-Mac-1 interaction limits arterial neointima formation in mice  Academic Article
• Intestinal Ischemia-Reperfusion Injury Leads to Inflammatory Changes in the Brain  Academic Article
• Intestinal adenoma formation and MYC activation are regulated by cooperation between MYB and Wnt signaling  Academic Article
• Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging  Academic Article
• Intravenous immunoglobulin (IVIg) dampens neuronal toll-like receptor-mediated responses in ischemia  Academic Article
• Intravenous immunoglobulin protects neurons against amyloid beta-peptide toxicity and ischemic stroke by attenuating multiple cell death pathways  Academic Article
• Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke  Academic Article
• Involvement of calpains in Ca2+-induced disruption of excitation-contraction coupling in mammalian skeletal muscle fibers  Academic Article
• Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis  Academic Article
• Iron homeostasis is maintained in the brain, but not the liver, following mild hypoxia  Academic Article
• Isolation of cell type-specific apoptotic bodies by fluorescence-activated cell sorting  Academic Article
• JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis, and Insulin Resistance in Obesity  Academic Article
• Ketogenic diet and olanzapine treatment alone and in combination reduce a pharmacologically-induced prepulse inhibition deficit in female mice  Academic Article
• Ketogenic diet prevents impaired prepulse inhibition of startle in an acute NMDA receptor hypofunction model of schizophrenia  Academic Article
• Kidney expression of glutathione peroxidase-1 is not protective against streptozotocin-induced diabetic nephropathy  Academic Article
• LDL receptor blockade reduces mortality in a mouse model of ischaemic stroke without improving tissue-type plasminogen activator-induced brain haemorrhage: towards pre-clinical simulation of symptomatic ICH  Academic Article
• LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival  Academic Article
• LMP2 immunoproteasome promotes lymphocyte survival by degrading apoptotic BH3-only proteins  Academic Article
• LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis  Academic Article
• LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L  Academic Article
• Lack of glutathione peroxidase-1 facilitates a pro-inflammatory and activated vascular endothelium  Academic Article
• Lack of the Antioxidant Enzyme Glutathione Peroxidase-1 Accelerates Atherosclerosis in Diabetic Apolipoprotein E–Deficient Mice  Academic Article
• Lack of the antioxidant glutathione peroxidase-1 (GPx1) exacerbates retinopathy of prematurity in mice  Academic Article
• Lack of the antioxidant glutathione peroxidase-1 does not increase atherosclerosis in C57BL/J6 mice fed a high-fat diet  Academic Article
• Legumain is activated in macrophages during pancreatitis  Academic Article
• Lifelong running reduces oxidative stress and degenerative changes in the testes of mice  Academic Article
• Links between l-glutamate transporters, Na+/K+-ATPase and cytoskeleton in astrocytes: Evidence following inhibition with rottlerin  Academic Article
• Localization and Regulation of Murine Esco2 During Male and Female Meiosis  Academic Article
• Location rather than CD62L phenotype is critical in the early establishment of influenza-specific CD8+ T cell memory  Academic Article
• Long-term behavioral and NMDA receptor effects of young-adult corticosterone treatment in BDNF heterozygous mice  Academic Article
• Loss of Host Type-I IFN Signaling Accelerates Metastasis and Impairs NK-cell Antitumor Function in Multiple Models of Breast Cancer  Academic Article
• Loss of the Pro-Apoptotic BH3-only Bcl-2 Family Member Bim Inhibits BCR Stimulation–induced Apoptosis and Deletion of Autoreactive B Cells  Academic Article
• Loss of the Wnt receptor frizzled 7 in the mouse gastric epithelium is deleterious and triggers rapid repopulation in vivo  Academic Article
• Lowering Corticosterone Levels Reinstates Hippocampal Brain-Derived Neurotropic Factor and Trkb Expression without Influencing Deficits in Hypothalamic Brain-Derived Neurotropic Factor Expression in Leptin Receptor-Deficient Mice  Academic Article
• M2 macrophage accumulation in the aortic wall during angiotensin II infusion in mice is associated with fibrosis, elastin loss, and elevated blood pressure  Academic Article
• MCMV-mediated Inhibition of the Pro-apoptotic Bak Protein Is Required for Optimal In Vivo Replication  Academic Article
• MEK/ERK-Mediated Phosphorylation of Bim Is Required to Ensure Survival of T and B Lymphocytes during Mitogenic Stimulation  Academic Article
• MK2 phosphorylates RIPK1 to prevent TNF-induced cell death  Academic Article
• Macrophage precursor cells from the left atrial appendage of the heart spontaneously reprogram into a C-kit+/CD45− stem cell-like phenotype  Academic Article
• Macrophages Are Mediators of Gastritis in Acute Helicobacter pylori Infection in C57BL/6 Mice  Academic Article
• Magnetic Resonance Imaging Contrast Agent Targeted Toward Activated Platelets Allows In Vivo Detection of Thrombosis and Monitoring of Thrombolysis  Academic Article
• Maternal fat feeding augments offspring nephron endowment in mice  Academic Article
• Maternal glucose intolerance reduces offspring nephron endowment and increases glomerular volume in adult offspring  Academic Article
• Maternal selenium deficiency during pregnancy in mice increases thyroid hormone concentrations, alters placental function and reduces fetal growth  Academic Article
• Maternal separation modifies behavioural and neuroendocrine responses to stress in CCR7 deficient mice  Academic Article
• Mcl-1 and Bcl-xL coordinately regulate megakaryocyte survival  Academic Article
• Mechanism of crosstalk inhibition of IL-6 signaling in response to LPS and TNFα  Academic Article
• Megakaryocyte maturation in long-term marrow culture  Academic Article
• Megakaryocytes co-localise with hemopoietic stem cells and release cytokines that up-regulate stem cell proliferation  Academic Article
• Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets  Academic Article
• Membrane-bound Fas ligand only is essential for Fas-induced apoptosis  Academic Article
• Memory regulatory T cells home to the lung and control influenza A virus infection  Academic Article
• Mesenchymal stromal cell turnover in the normal adult lung revisited  Academic Article
• Metabolic remodeling, inflammasome activation, and pyroptosis in macrophagesstimulated by Porphyromonas gingivalis and its outer membrane vesicles  Academic Article
• Metabotropic glutamate 5 receptors regulate sensitivity to ethanol in mice  Academic Article
• Metabotropic glutamate receptors mediate lipopolysaccharide-induced fever and sickness behavior  Academic Article
• Mice Deficient in Perforin, CD4+ T Cells, or CD28-Mediated Signaling Maintain the Typical Immunodominance Hierarchies of CD8+ T-Cell Responses to Influenza Virus  Academic Article
• Mice deficient in heparanase exhibit impaired dendritic cell migration and reduced airway inflammation  Academic Article
• Mice deficient in the alpha subunit of Gz show changes in pre-pulse inhibition, anxiety and responses to 5-HT1A receptor stimulation, which are strongly dependent on the genetic background  Academic Article
• Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8+ T Cells  Academic Article
• Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling  Academic Article
• Mining the plasma cell transcriptome for novel cell surface proteins  Academic Article
• Mitochondrial content is preserved throughout disease progression in the mdx mouse model of Duchenne muscular dystrophy, regardless of taurine supplementation.  Academic Article
• Mixed Proteasomes Function To Increase Viral Peptide Diversity and Broaden Antiviral CD8+ T Cell Responses  Academic Article
• Modafinil disrupts prepulse inhibition in mice: Strain differences and involvement of dopaminergic and serotonergic activation  Academic Article
• Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal  Academic Article
• Modification of Cysteine Residues In Vitro and In Vivo Affects the Immunogenicity and Antigenicity of Major Histocompatibility Complex Class I–restricted Viral Determinants  Academic Article
• Modulatory Effects of Sex Steroid Hormones on Brain-Derived Neurotrophic Factor-Tyrosine Kinase B Expression during Adolescent Development in C57Bl/6 Mice  Academic Article
• Molecular Magnetic Resonance Imaging Allows the Detection of Activated Platelets in a New Mouse Model of Coronary Artery Thrombosis  Academic Article
• Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD  Academic Article
• Monounsaturated fatty acid-enriched high-fat diets impede adipose NLRP3 inflammasome-mediated IL-1β secretion and insulin resistance despite obesity  Academic Article
• Morphological and biochemical alterations of skeletal muscles from the genetically obese (ob/ob) mouse  Academic Article
• Mouse granzyme A induces a novel death with writhing morphology that is mechanistically distinct from granzyme B-induced apoptosis  Academic Article
• Mouse thymus dendritic cells: kinetics of development and changes in surface markers during maturation  Academic Article
• Multiphoton imaging reveals a new leukocyte recruitment paradigm in the glomerulus  Academic Article
• Multiple genetic loci modify susceptibility to plasmacytoma-related morbidity in E -v-abl transgenic mice  Academic Article
• Multiple pathological mechanisms contribute to hippocampal damage in the experimental autoimmune encephalomyelitis model of multiple sclerosis  Academic Article
• Multiplexed Division Tracking Dyes for Proliferation-Based Clonal Lineage Tracing  Academic Article
• Multisensory Stimulation Improves Functional Recovery and Resting-State Functional Connectivity in the Mouse Brain after Stroke  Academic Article
• Muscle Stem Cell Fate Is Controlled by the Cell-Polarity Protein Scrib  Academic Article
• Mutant TRP53 exerts a target gene-selective dominant-negative effect to drive tumor development  Academic Article
• Mutation of NIMA-related kinase 1 (NEK1) leads to chromosome instability  Academic Article
• Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease  Academic Article
• Mutually exclusive regulation of T cell survival by IL-7R and antigen receptor-induced signals  Academic Article
• Myocardial autophagy activation and suppressed survival signaling is associated with insulin resistance in fructose-fed mice  Academic Article
• Myocardial insulin resistance, metabolic stress and autophagy in diabetes  Academic Article
• Myocardial oxidative stress contributes to transgenic beta(2)-adrenoceptor activation-induced cardiomyopathy and heart failure  Academic Article
• NADPH-Induced Contractions of Mouse Aorta Do Not Involve NADPH Oxidase: A Role for P2X Receptors  Academic Article
• NETosis is required for S100A8/A9-induced granulopoiesis after myocardial infarction  Academic Article
• NKT TCR Recognition of CD1d-α-C-Galactosylceramide  Academic Article
• NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease  Academic Article
• NY-ESO-1 Protein Formulated in ISCOMATRIX Adjuvant Is a Potent Anticancer Vaccine Inducing Both Humoral and CD8+ T-Cell-Mediated Immunity and Protection against NY-ESO-1+ Tumors  Academic Article
• Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia  Academic Article
• Ndfip1 represses cell proliferation by controlling Pten localization and signaling specificity  Academic Article
• Nedd4 family interacting protein 1 (Ndfip1) is required for ubiquitination and nuclear trafficking of BRCA1-associated ATM activator 1 (BRAT1) during the DNA damage response  Academic Article
• Nedd4-WW Domain-Binding Protein 5 (Ndfip1) Is Associated with Neuronal Survival after Acute Cortical Brain Injury  Academic Article
• Neurodevelopmental and neuropsychiatric behaviour defects arise from 14-3-3ζ deficiency  Academic Article
• Neuronal low-density lipoprotein receptor-related protein 1 (LRP1) enhances the anti-apoptotic effect of intravenous immunoglobulin (IVIg) in ischemic stroke  Academic Article
• Neuroprotective actions of a histidine analogue in models of ischemic stroke  Academic Article
• Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke  Academic Article
• Neutrophil Activation Is Attenuated by High-Density Lipoprotein and Apolipoprotein A-I in In Vitro and In Vivo Models of Inflammation  Academic Article
• Neutrophil-derived S100 calcium-binding proteins A8/A9 promote reticulated thrombocytosis and atherogenesis in diabetes  Academic Article
• New Murine Model of Spontaneous Autologous Tissue Engineering, Combining an Arteriovenous Pedicle with Matrix Materials  Academic Article
• New role for the (pro)renin receptor in T-cell development  Academic Article
• Nfil3 is required for the development of all innate lymphoid cell subsets  Academic Article
• Nitric oxide synthase II gene disruption: Implications for tumor growth and vascular endothelial growth factor production  Academic Article
• Nitroxide-Loaded Hexosomes Provide MRI Contrast in Vivo  Academic Article
• Nitroxyl (HNO) reduces endothelial and monocyte activation and promotes M2 macrophage polarization  Academic Article
• Non-invasive Assessment of the Efficacy of New Therapeutics for Intestinal Pathologies Using Serial Endoscopic Imaging of Live Mice  Academic Article
• Non-invasive assessment of dorsiflexor muscle function in mice  Academic Article
• Noninvasive assessment of altered activity following restraint in mice using an automated physiological monitoring system  Academic Article
• Normal inflammation and regeneration of muscle following injury require osteopontin from both muscle and non-muscle cells  Academic Article
• Notch Signaling Regulates Mammary Stem Cell Function and Luminal Cell-Fate Commitment  Academic Article
• Novel Single-Chain Antibody-Targeted Microbubbles for Molecular Ultrasound Imaging of Thrombosis  Academic Article
• Nox1 Oxidase Suppresses Influenza A Virus-Induced Lung Inflammation and Oxidative Stress  Academic Article
• Nox1 upregulates the function of vascular T-type calcium channels following chronic nitric oxide deficit  Academic Article
• Nox2 oxidase activity accounts for the oxidative stress and vasomotor dysfunction in mouse cerebral arteries following ischemic stroke  Academic Article
• O2•−production at 37°C plays a critical role in depressing tetanic force of isolated rat and mouse skeletal muscle  Academic Article
• Oestrogen modulation of the effect of 8-OH-DPAT on prepulse inhibition: effects of aromatase deficiency and castration in mice  Academic Article
• Opposing roles of gp130-mediated STAT-3 and ERK-1/2 signaling in liver progenitor cell migration and proliferation  Academic Article
• Optimal conditions required for influenza A infection‐enhanced cross‐priming of CD8 + T cells specific to cell‐associated antigens  Academic Article
• Osteoarthritis-associated basic calcium phosphate crystals induce pro-inflammatory cytokines and damage-associated molecules via activation of Syk and PI3 kinase  Academic Article
• Osteopontin and skeletal muscle myoblasts: Association with muscle regeneration and regulation of myoblast function in vitro  Academic Article
• Osteopontin deficiency delays inflammatory infiltration and the onset of muscle regeneration in a mouse model of muscle injury  Academic Article
• Over-Expression of DSCR1 Protects against Post-Ischemic Neuronal Injury  Academic Article
• Overexpression of the anti-apoptotic protein AVEN contributes to increased malignancy in hematopoietic neoplasms  Academic Article
• Oxidative and excitotoxic insults exert differential effects on spinal motoneurons and astrocytic glutamate transporters: Implications for the role of astrogliosis in amyotrophic lateral sclerosis  Academic Article
• PBT2 inhibits glutamate-induced excitotoxicity in neurons through metal-mediated preconditioning  Academic Article
• Paneth cell marker expression in intestinal villi and colon crypts characterizes dietary induced risk for mouse sporadic intestinal cancer  Academic Article
• Pannexin 1 Channels as an Unexpected New Target of the Anti-Hypertensive Drug Spironolactone  Academic Article
• Parvalbumin Gene Transfer Impairs Skeletal Muscle Contractility in Old Mice  Academic Article
• Pegylation of High-Density Lipoprotein Decreases Plasma Clearance and Enhances Antiatherogenic Activity  Academic Article
• Phagocyte-Derived Reactive Oxygen Species Do Not Influence the Progression of Murine Blood-Stage Malaria Infections  Academic Article
• Pharmacological inhibition of ALDH1A in mice decreases all-trans retinoic acid concentrations in a tissue specific manner  Academic Article
• Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage and dysfunction in salt-sensitive hypertension.  Academic Article
• Phenanthrolines protect astrocytes from hemin without chelating iron  Academic Article
• Phencyclidine-induced locomotor hyperactivity is enhanced in mice after stereotaxic brain serotonin depletion  Academic Article
• Phenotypes of neural-crest-derived cells in vagal and sacral pathways  Academic Article
• Phenotypic disruption to orofacial movement topography in conditional mutants with generalized CamKIIa/Cre D1Tox versus striatal-specific DARPP-32/Cre D1Tox ablation of D1 dopamine receptor-expressing cells  Academic Article
• Phenotypically identical hemopoietic stem cells isolated from different regions of bone marrow have different biologic potential  Academic Article
• Phosphatidylinositol mannosides: Synthesis and suppression of allergic airway disease  Academic Article
• Physiological expression of the PI3K-activating mutation Pik3ca H1047R combines with Apc loss to promote development of invasive intestinal adenocarcinomas in mice  Academic Article
• Physiological restraint of Bak by Bcl-x(L) is essential for cell survival  Academic Article
• Pin1 promotes neuronal death in stroke by stabilizing notch intracellular domain  Academic Article
• Pivotal role for beta-1 integrin in neurovascular remodelling after ischemic stroke  Academic Article
• Plasmalogen modulation attenuates atherosclerosis in ApoE- and ApoE/GPx1-deficient mice  Academic Article
• Platelet-targeted delivery of peripheral blood mononuclear cells to the ischemic heart restores cardiac function after ischemia-reperfusion injury  Academic Article
• Platelets drive neuroinflammation and target grey matter and the retina in autoimmune-mediated encephalomyelitis  Academic Article
• Plumbagin, a novel Nrf2/ARE activator, protects against cerebral ischemia  Academic Article
• Polarity protein scrib facilitates endothelial inflammatory signaling  Academic Article
• Postchemotherapy and Tumor-Selective Targeting with the La-Specific DAB4 Monoclonal Antibody Relates to Apoptotic Cell Clearance  Academic Article
• Potencies of Human Immunodeficiency Virus Protease Inhibitors In Vitro against Plasmodium falciparum and In Vivo against Murine Malaria  Academic Article
• PreImplantation factor prevents atherosclerosis via its immunomodulatory effects without affecting serum lipids  Academic Article
• Prepulse inhibition of acoustic startle in aromatase knock-out mice: effects of age and gender  Academic Article
• Pressor response to angiotensin II is enhanced in aged mice and associated with inflammation, vasoconstriction and oxidative stress  Academic Article
• Primary Tumor Hypoxia Recruits CD11b+/Ly6Cmed/Ly6G+ Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche  Academic Article
• Pro-apoptotic Bim suppresses breast tumor cell metastasis and is a target gene of SNAI2  Academic Article
• Proapoptotic Bcl-2 family member Bim is involved in the control of mast cell survival and is induced together with Bcl-XL upon IgE-receptor activation  Academic Article
• Prosurvival Bcl-2 family members reveal a distinct apoptotic identity between conventional and plasmacytoid dendritic cells  Academic Article
• Protective effect of inflammasome activation by hydrogen peroxide in a mouse model of septic shock  Academic Article
• Protective effects of dietary supplementation with a combination of nutrients in a transgenic mouse model of Alzheimer's disease  Academic Article
• Protective role for toll-like receptor-9 in the development of atherosclerosis in apolipoprotein E–deficient mice  Academic Article
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• Psychotropic drug-induced locomotor hyperactivity and prepulse inhibition regulation in male and female aromatase knockout (ArKO) mice: role of dopamine D1 and D2 receptors and dopamine transporters  Academic Article
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• RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis  Academic Article
• RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation  Academic Article
• RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL  Academic Article
• Rapamycin increases neuronal survival, reduces inflammation and astrocyte proliferation after spinal cord injury  Academic Article
• Reactive oxygen species are the major antibacterials against Salmonella Typhimurium purine auxotrophs in the phagosome of RAW 264.7 cells  Academic Article
• Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition  Academic Article
• Recombinant interleukin-6 protects mice against experimental bacterial infection.  Academic Article
• Recruitment of old genes to new functions: evidences obtained by comparing the orthologues of human XLMR genes in mouse and chicken  Academic Article
• Reduced plaque formation induced by rosiglitazone in an STZ-diabetes mouse model of atherosclerosis is associated with downregulation of adhesion molecules  Academic Article
• Reduction in sphingosine kinase 1 influences the susceptibility to dengue virus infection by altering antiviral responses  Academic Article
• Reduction of cerebral infarct volume by apocynin requires pretreatment and is absent in Nox2-deficient mice  Academic Article
• Regulation of Hematopoietic Stem and Progenitor Cell Mobilization by Cholesterol Efflux Pathways  Academic Article
• Regulation of glutamate transporters in astrocytes: Evidence for a relationship between transporter expression and astrocytic phenotype  Academic Article
• Regulation of hepatic LDL receptors by mTORC1 and PCSK9 in mice  Academic Article
• Regulation of interleukin‐1β by interferon‐γ is species specific, limited by suppressor of cytokine signalling 1 and influences interleukin‐17 production  Academic Article
• Regulation of mouse Heparanase gene expression in T lymphocytes and tumor cells  Academic Article
• Regulatory T Cells Suppress Effector T Cell Proliferation by Limiting Division Destiny  Academic Article
• Relaxin-1–deficient mice develop an age-related progression of renal fibrosis  Academic Article
• Replication asynchrony and differential condensation of X chromosomes in female platypus (Ornithorhynchus anatinus)  Academic Article
• Repurposing drugs targeting the P2X7 receptor to limit hyperinflammation and disease during influenza virus infection  Academic Article
• Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth  Academic Article
• Resolution of glucose intolerance in long-term high-fat, high-sucrose-fed mice  Academic Article
• Response of Apcmin and A33ΔNβ-cat mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)  Academic Article
• Retinal microglial activation following topical application of intracellular toll-like receptor ligands  Academic Article
• Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation  Academic Article
• Retinoic acid regulates Kit translation during spermatogonial differentiation in the mouse  Academic Article
• Reversal in the Immunodominance Hierarchy in Secondary CD8+ T Cell Responses to Influenza A Virus: Roles for Cross-Presentation and Lysis-Independent Immunodomination  Academic Article
• Reversal of Vascular Macrophage Accumulation and Hypertension by a CCR2 Antagonist in Deoxycorticosterone/Salt-Treated Mice  Academic Article
• Revisiting cardiac cellular composition  Academic Article
• Role of IL-6 in activation of T cells for acquired cellular resistance to Listeria monocytogenes  Academic Article
• Role of Interleukin 17 in Inflammation, Atherosclerosis, and Vascular Function in Apolipoprotein E-Deficient Mice  Academic Article
• Role of Nox isoforms in angiotensin II-induced oxidative stress and endothelial dysfunction in brain  Academic Article
• Role of Plasmodium berghei cGMP-dependent Protein Kinase in Late Liver Stage Development  Academic Article
• Role of T Lymphocytes and Interferon-γ in Ischemic Stroke  Academic Article
• Role of chemokine RANTES in the regulation of perivascular inflammation, T-cell accumulation, and vascular dysfunction in hypertension  Academic Article
• Role of interleukin-6 in T-cell activation during primary and secondary infection with Listeria monocytogenes.  Academic Article
• Role of local production of endothelium-derived nitric oxide on cGMP signaling and S-nitrosylation  Academic Article
• Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalk  Academic Article
• SGLT2 inhibition reduces atherosclerosis by enhancing lipoprotein clearance in Ldlr −/− type 1 diabetic mice  Academic Article
• SIRT2 inhibition confers neuroprotection by downregulation of FOXO3a and MAPK signaling pathways in ischemic stroke  Academic Article
• SMAD3 dosage determines androgen responsiveness and sets the pace of postnatal testis development  Academic Article
• SOCS-6 Binds to Insulin Receptor Substrate 4, and Mice Lacking the SOCS-6 Gene Exhibit Mild Growth Retardation  Academic Article
• SOD1 Mutations Causing Familial Amyotrophic Lateral Sclerosis Induce Toxicity in Astrocytes: Evidence for Bystander Effects in a Continuum of Astrogliosis  Academic Article
• STAT3 Activation Regulates Growth, Inflammation, and Vascularization in a Mouse Model of Gastric Tumorigenesis  Academic Article
• Saikosaponin a inhibits influenza A virus replication and lung immunopathology  Academic Article
• Scrib:Rac1 interactions are required for the morphogenesis of the ventricular myocardium  Academic Article
• Selection of an adjuvant for vaccination with the malaria antigen, MSA-2  Academic Article
• Selective enhancement of NMDA receptor-mediated locomotor hyperactivity by male sex hormones in mice  Academic Article
• Semiquantitative Proteomics Enables Mapping of Murine Neutrophil Dynamics following Lethal Influenza Virus Infection  Academic Article
• Serelaxin treatment reverses vascular dysfunction and left ventricular hypertrophy in a mouse model of Type 1 diabetes  Academic Article
• Serglycin determines secretory granule repertoire and regulates natural killer cell and cytotoxic T lymphocyte cytotoxicity  Academic Article
• Sex differences in the adolescent developmental trajectory of parvalbumin interneurons in the hippocampus: A role for estradiol  Academic Article
• Shear-sensitive nanocapsule drug release for site-specific inhibition of occlusive thrombus formation  Academic Article
• Short-term environmental enrichment, and not physical exercise, alleviate cognitive decline and anxiety from middle age onwards without affecting hippocampal gene expression  Academic Article
• Side population in adult murine epidermis exhibits phenotypic and functional characteristics of keratinocyte stem cells  Academic Article
• Single β³-amino acid substitutions to MOG peptides suppress the development of experimental autoimmune encephalomyelitis  Academic Article
• Single-cell transcriptomics identifies the adaptation of Scart1⁺ Vγ6⁺ T cells to skin residency as activated effector cells  Academic Article
• Site-Specific Antiatherogenic Effect of the Antioxidant Ebselen in the Diabetic Apolipoprotein E–Deficient Mouse  Academic Article
• Small-molecule-biased formyl peptide receptor agonist compound 17b protects against myocardial ischaemia-reperfusion injury in mice  Academic Article
• Social approach, anxiety, and altered tryptophan hydroxylase 2 activity in juvenile BALB/c and C57BL/6J mice  Academic Article
• Sox9 drives columnar differentiation of esophageal squamous epithelium: A possible role in the pathogenesis of Barrett's esophagus  Academic Article
• Specific inhibition of PI3K p110δ inhibits CSF-1-induced macrophage spreading and invasive capacity  Conference Paper
• Src Homology 3-Domain Growth Factor Receptor-Bound 2-Like (Endophilin) Interacting Protein 1, a Novel Neuronal Protein that Regulates Energy Balance  Academic Article
• Src family kinase expression and subcellular localization in macrophages: implications for their role in CSF-1-induced macrophage migration  Academic Article
• Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from type 2 diabetes patients: Rescue by α-ketoglutarate and TET-TDG functional reactivation  Academic Article
• Stereological Assessment of Developing Mouse Ovarian Follicles in an in vitro Culture System  Academic Article
• Stochastic measurement models for quantifying lymphocyte responses using flow cytometry  Academic Article
• Store-operated calcium entry remains fully functional in aged mouse skeletal muscle despite a decline in STIM1 protein expression  Academic Article
• Strain-related effects of fenbendazole treatment on murine experimental autoimmune encephalomyelitis  Academic Article
• Strain-transcending immune response generated by chimeras of the malaria vaccine candidate merozoite surface protein 2  Academic Article
• Stretched cell cycle model for proliferating lymphocytes  Academic Article
• Sulindac activates NF-κB signaling in colon cancer cells  Academic Article
• Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade  Academic Article
• Synthesis and Antitumor Properties ofN-[2-(Dimethylamino)ethyl]carboxamide Derivatives of Fused Tetracyclic Quinolines and Quinoxalines:  A New Class of Putative Topoisomerase Inhibitors  Academic Article
• Synthesis and in Vivo Evaluation of [¹²³I]Melanin-Targeted Agents  Academic Article
• Systematic Search Fails to Detect Immunogenic MHC Class-I-Restricted Determinants Encoded by Influenza A Virus Noncoding Sequences  Academic Article
• T Cell Determinants Incorporating β-Amino Acid Residues Are Protease Resistant and Remain Immunogenic In Vivo  Academic Article
• T Lymphocytes and Vascular Inflammation Contribute to Stress-Dependent Hypertension  Academic Article
• T cells recognizing a 11mer influenza peptide complexed to H-2D(b) show promiscuity for peptide length  Academic Article
• TCF-1 limits the formation of Tc17 cells via repression of the MAF-RORγt axis  Academic Article
• TGF-βRII Rescues Development of Small Intestinal Epithelial Cells in Elf3-Deficient Mice  Academic Article
• THE IMPACT OF IMMUNIZATION ON COMPETITION WITHINPLASMODIUMINFECTIONS  Academic Article
• TLR9 and TLR7/8 activation induces formation of keratic precipitates and giant macrophages in the mouse cornea  Academic Article
• TNF signalling via the TNF receptors mediates the effects of exercise on cognition-like behaviours.  Academic Article
• TNF-alpha and its receptors modulate complex behaviours and neurotrophins in transgenic mice  Academic Article
• TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice  Academic Article
• Taenia taeniaeformis: Immunoprecipitation analysis of the protein antigens of oncospheres and larvae  Academic Article
• Targeting Antigen to Mouse Dendritic Cells via Clec9A Induces Potent CD4 T Cell Responses Biased toward a Follicular Helper Phenotype  Academic Article
• Targeting CD39 Toward Activated Platelets Reduces Systemic Inflammation and Improves Survival in Sepsis  Academic Article
• Targeting Ligand-Induced Binding Sites on GPIIb/IIIa via Single-Chain Antibody Allows Effective Anticoagulation Without Bleeding Time Prolongation  Academic Article
• Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53  Academic Article
• Temporal and Spatial Dynamics of Cerebral Immune Cell Accumulation in Stroke  Academic Article
• The Biodistribution and Immune Suppressive Effects of Breast Cancer-Derived Exosomes  Academic Article
• The Cell Adhesion Molecule L1 Is Required for Chain Migration of Neural Crest Cells in the Developing Mouse Gut  Academic Article
• The Comparative Roles of Suppressor of Cytokine Signaling-1 and -3 in the Inhibition and Desensitization of Cytokine Signaling  Academic Article
• The Early Expression of Glycoprotein B from Herpes Simplex Virus Can Be Detected by Antigen-Specific CD8+ T Cells  Academic Article
• The Expression of a Metallothionein-Ovine Growth Hormone Fusion Gene in Transgenic Mice Does Not Impair Fertility but Results in Pathological Lesions in the Liver  Academic Article
• The Interleukin-6 Family Cytokine Interleukin-11 Regulates Homeostatic Epithelial Cell Turnover and Promotes Gastric Tumor Development  Academic Article
• The Mitochondria-Targeted Methylglyoxal Sequestering Compound, MitoGamide, Is Cardioprotective in the Diabetic Heart  Academic Article
• The NUP98-HOXD13 fusion oncogene induces thymocyte self-renewal via Lmo2/Lyl1  Academic Article
• The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis  Academic Article
• The Receptor Tyrosine Kinase EPHB4 Has Tumor Suppressor Activities in Intestinal Tumorigenesis  Academic Article
• The Rho kinase inhibitor Fasudil up-regulates astrocytic glutamate transport subsequent to actin remodelling in murine cultured astrocytes  Academic Article
• The Strength of T Cell Receptor Signal Controls the Polarization of Cytotoxic Machinery to the Immunological Synapse  Academic Article
• The TAM receptor TYRO3 is a critical regulator of myelin thickness in the central nervous system  Academic Article
• The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity  Academic Article
• The anti-platelet effects of apocynin in mice are not mediated by inhibition of NADPH oxidase activity  Academic Article
• The asymmetric cell division regulators Par3, Scribble and Pins/Gpsm2 are not essential for erythroid development or enucleation  Academic Article
• The calcineurin signal transduction pathway is essential for successful muscle regeneration in mdx dystrophic mice  Academic Article
• The class II PI 3-kinase, PI3KC2α, links platelet internal membrane structure to shear-dependent adhesive function  Academic Article
• The contribution of Nox4 to NADPH oxidase activity in mouse vascular smooth muscle  Academic Article
• The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin  Academic Article
• The effect of lipopolysaccharide on cholecystokinin in murine plasma and tissue  Academic Article
• The effect of low estrogen state on serotonin transporter function in mouse hippocampus: A behavioral and electrochemical study  Academic Article
• The effect of the antipsychotic drug quetiapine and its metabolite norquetiapine on acute inflammation, memory and anhedonia  Academic Article
• The effects of aerobic exercise on depression-like, anxiety-like, and cognition-like behaviours over the healthy adult lifespan of C57BL/6 mice  Academic Article
• The effects of cooling mouse oocytes  Academic Article
• The effects of short-term and long-term environmental enrichment on locomotion, mood-like behavior, cognition and hippocampal gene expression  Academic Article
• The endoglycosidase heparanase enters the nucleus of T lymphocytes and modulates H3 methylation at actively transcribed genes via the interplay with key chromatin modifying enzymes  Academic Article
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• The enteric nervous system undergoes significant chemical and synaptic maturation during adolescence in mice  Academic Article
• The fusion partner specifies the oncogenic potential of NUP98 fusion proteins  Academic Article
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• The hypoxia imaging agent Cu ^II(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease  Academic Article
• The impact of non-severe burn injury on cardiac function and long-term cardiovascular pathology  Academic Article
• The migratory behavior of immature enteric neurons  Academic Article
• The novel small-molecule annexin-a1 mimetic, compound 17b, elicits vasoprotective actions in streptozotocin-induced diabetic mice  Academic Article
• The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) activator dh404 protects against diabetes-induced endothelial dysfunction  Academic Article
• The organotellurium compound ammonium trichloro(dioxoethylene-0,0') tellurate enhances neuronal survival and improves functional outcome in an ischemic stroke model in mice  Academic Article
• The polarity protein Scrib limits atherosclerosis development in mice  Academic Article
• The protease cathepsin L regulates Th17 cell differentiation  Academic Article
• The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism  Academic Article
• The relationship between bone, hemopoietic stem cells, and vasculature  Academic Article
• The role of BH3-only protein Bim extends beyond inhibiting Bcl-2–like prosurvival proteins  Academic Article
• The role of CCK2 receptors in energy homeostasis: insights from the CCK2 receptor-deficient mouse  Academic Article
• The role of Tenascin C in the lymphoid progenitor cell niche  Academic Article
• The role of the voltage-gated potassium channel proteins Kv8.2 and Kv2.1 in vision and retinal disease: Insights from the study of mouse gene knock-out mutations  Academic Article
• The selective TrkA agonist, gambogic amide, promotes osteoblastic differentiation and improves fracture healing in mice  Academic Article
• The selectivty and anti-metastatic activity of oral bioavailable butyric acid prodrugs  Academic Article
• The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells  Academic Article
• The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue–resident regulatory T cells  Academic Article
• Therapeutic Targeting of IL-6 Trans Signaling Counteracts STAT3 Control of Experimental Inflammatory Arthritis  Academic Article
• Therapeutic inhibition of Jak activity inhibits progression of gastrointestinal tumors in mice  Academic Article
• Therapeutic potential of PEGylated insulin-like growth factor I for skeletal muscle disease evaluated in two murine models of muscular dystrophy  Academic Article
• Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with α9β1 and α4β1 integrins  Academic Article
• Thrombin-stimulated growth factor and cytokine expression in osteoblasts is mediated by protease-activated receptor-1 and prostanoids  Academic Article
• Thymocyte subsets transformed by Abelson murine leukemia virus.  Academic Article
• Thymosin beta(4) Administration Enhances Fracture Healing in Mice  Academic Article
• Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling  Academic Article
• Tissue-selective restriction of RNA editing of CaV1.3 by splicing factor SRSF9  Academic Article
• Toll-Like Receptor 3 Is a Negative Regulator of Embryonic Neural Progenitor Cell Proliferation  Academic Article
• Towards effective and safe thrombolysis and thromboprophylaxis  Academic Article
• Toxicity of eosinophil MBP Is repressed by intracellular crystallization and promoted by extracellular aggregation  Academic Article
• Tranexamic acid modulates the cellular immune profile after traumatic brain injury in mice without hyperfibrinolysis  Academic Article
• Transcription Factor IRF4 Regulates Germinal Center Cell Formation through a B Cell–Intrinsic Mechanism  Academic Article
• Transcription Factor T-bet in B Cells Modulates Germinal Center Polarization and Antibody Affinity Maturation in Response to Malaria  Academic Article
• Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells  Academic Article
• Transcriptome analysis reveals intermittent fasting-induced genetic changes in ischemic stroke  Academic Article
• Transcriptomic profiling of astrocytes treated with the Rho kinase inhibitor Fasudil reveals cytoskeletal and pro-survival responses  Academic Article
• Transformation of Astrocytes in Transgenic Mice Expressing SV40 T Antigen under the Transcriptional Control of the Glial Fibrillary Acidic Protein Promoter  Academic Article
• Treatment with an interleukin-1 receptor antagonist mitigates neuroinflammation and brain damage after polytrauma  Academic Article
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• Trim33 Binds and Silences a Class of Young Endogenous Retroviruses in the Mouse Testis; a Novel Component of the Arms Race between Retrotransposons and the Host Genome  Academic Article
• Tumor Progression Locus 2 (Map3k8) Is Critical for Host Defense against Listeria monocytogenes and IL-1β Production  Academic Article
• Tumor necrosis factor alpha and its receptors in behaviour and neurobiology of adult mice, in the absence of an immune challenge  Academic Article
• Tumor-induced anorexia and weight loss are mediated by the TGF-β superfamily cytokine MIC-1  Academic Article
• Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes  Academic Article
• Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2  Academic Article
• Ultrastructure of primitive hematopoietic stem cells isolated using probes of functional status  Academic Article
• Unaltered susceptibility to BSE in transgenic mice expressing human prion protein  Academic Article
• Unexpected Role for the Immunoproteasome Subunit LMP2 in Antiviral Humoral and Innate Immune Responses  Academic Article
• Unexpected link between an antibiotic, pannexin channels and apoptosis  Academic Article
• Upexpression of BHLHE40 in gastric epithelial cells increases CXCL12 production through interaction with p-STAT3 in Helicobacter pylori-associated gastritis  Academic Article
• Uptake and toxicity of hemin and iron in cultured mouse astrocytes  Academic Article
• Urine proteome analysis as a discovery tool in patients with deep vein thrombosis and pulmonary embolism  Academic Article
• VACCINATION AGAINST CUTANEOUS LEISHMANIASIS IN MICE USING NONPATHOGENIC CLONED PROMASTIGOTES OF LEISHMANIA MAJOR AND IMPORTANCE OF ROUTE OF INJECTION  Academic Article
• Vascular Normalization by Loss of Siah2 Results in Increased Chemotherapeutic Efficacy  Academic Article
• Vasoprotective and Atheroprotective Effects of Angiotensin (1-7) in Apolipoprotein E–Deficient Mice  Academic Article
• Vasorelaxant and antiaggregatory actions of the nitroxyl donor isopropylamine NONOate are maintained in hypercholesterolemia  Academic Article
• Visualization of Activated Platelets by Targeted Magnetic Resonance Imaging Utilizing Conformation-Specific Antibodies against Glycoprotein IIb/IIIa  Academic Article
• Vitamin B6 Is Required for Full Motility and Virulence in Helicobacter pylori  Academic Article
• Vitamin D-3 Supplementation Reduces Subsequent Brain Injury and Inflammation Associated with Ischemic Stroke  Academic Article
• XIAP discriminates between type I and type II FAS-induced apoptosis  Academic Article
• XIAP-deficiency leads to delayed lobuloalveolar development in the mammary gland  Academic Article
• c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host–microbiota homeostasis  Academic Article
• c-Myb is critical for murine colon development  Academic Article
• c-Myb is required for progenitor cell homeostasis in colonic crypts  Academic Article
• cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1-and RIPK3-dependent manner  Academic Article
• mTORC1 inhibition restricts infammation-associated gastrointestinal tumorigenesis in mice  Academic Article
• miR33 Inhibition Overcomes Deleterious Effects of Diabetes Mellitus on Atherosclerosis Plaque Regression in Mice  Academic Article
• microRNA-367-3p regulation of GPRC5A is suppressed in ischemic stroke  Academic Article
• α-Synuclein transgenic mice exhibit reduced anxiety-like behaviour  Academic Article
• β-Adrenoceptor stimulation upregulates cardiac expression of galectin-3 and BIM through the Hippo signalling pathway.  Academic Article
• “Interrogating the grainyhead-like 2 (Grhl2) genomic locus identifies an enhancer element that regulates palatogenesis in mouse”  Academic Article