subject area of

• A Mechanistic Model for Paradoxical Platelet Activation by Ligand-Mimetic α IIb β 3 (GPIIb/IIIa) Antagonists  Academic Article
• A deletion in the ?? subunit locks platelet integrin ??IIb??3 into a high affinity state  Academic Article
• Abciximab, Eptifibatide, and Tirofiban Exhibit Dose-dependent Potencies to Dissolve Platelet Aggregates  Academic Article
• Activating Effects of GPIIb/IIIa Blockers: An Intrinsic Consequence of Ligand- Mimetic Properties  Academic Article
• An Activation-Specific Platelet Inhibitor That Can Be Turned On/Off by Medically Used Hypothermia  Academic Article
• Celastrol, a Triterpene Extracted From Tripterygium wilfordii Hook F, Inhibits Platelet Activation  Academic Article
• Conformation-Specific Blockade of the Integrin GPIIb/IIIa  Academic Article
• Critical temperature ranges of hypothermia-induced platelet activation: Possible implications for cooling patients in cardiac surgery  Academic Article
• Delayed targeting of CD39 to activated platelet GPIIb/IIIa via a single-chain antibody: breaking the link between antithrombotic potency and bleeding?  Academic Article
• Distinct roles of ligand affinity and cytoskeletal anchorage in αIIbβ3(GP IIb/IIIa)-mediated cell aggregation and adhesion  Academic Article
• Dual targeting improves capture of ultrasound microbubbles towards activated platelets but yields no additional benefit for imaging of arterial thrombosis  Academic Article
• Dual-contrast molecular imaging allows noninvasive characterization of myocardial ischemia/reperfusion injury after coronary vessel occlusion in mice by magnetic resonance imaging  Academic Article
• Effects of different thrombolytic treatment regimen with abciximab and tirofiban on platelet aggregation and platelet-leukocyte interactions: A subgroup analysis from the GUSTO V and FASTER trials  Academic Article
• Evidence for a differential functional regulation of the two β3-integrins αVβ3 and αIIbβ3  Academic Article
• Flow Cytometric Monitoring of Glycoprotein IIb/IIIa Blockade and Platelet Function in Patients With Acute Myocardial Infarction Receiving Reteplase, Abciximab, and Ticlopidine  Academic Article
• Forget about thrombosis: Platelets and Alzheimer’s disease, yet another sticky situation  Academic Article
• Functionalized Magnetic Resonance Contrast Agent Selectively Binds to Glycoprotein IIb/IIIa on Activated Human Platelets under Flow Conditions and Is Detectable at Clinically Relevant Field Strengths  Academic Article
• GPIIb/IIIa inhibitors: From bench to bedside and back to bench again  Academic Article
• GPIIb/IIIa-Blockade zur Optimierung der Thrombolyse bei aktuem Myokardinfarkt  Academic Article
• Genetic transfer of fusion proteins effectively inhibits VCAM-1-mediated cell adhesion and transmigration via inhibition of cytoskeletal anchorage  Academic Article
• Highly Sensitive Detection of Minimal Cardiac Ischemia using Positron Emission Tomography Imaging of Activated Platelets  Academic Article
• Human IgG Monoclonal Anti-αIIbβ3-Binding Fragments Derived from Immunized Donors Using Phage Display  Academic Article
• Improving selection of αIIbβ3-binding phage antibodies with increased reactivity derived from immunized donors  Academic Article
• Induction of Fibrinogen Binding and Platelet Aggregation as a Potential Intrinsic Property of Various Glycoprotein IIb/IIIa (IIbβ3) Inhibitors  Academic Article
• Inhaled Nitric Oxide Inhibits Human Platelet Aggregation, P-Selectin Expression, and Fibrinogen Binding In Vitro and In Vivo  Academic Article
• Inhibition of platelet activation and aggregation  Academic Article
• Integrin cytoplasmic domains mediate inside-out signal transduction  Academic Article
• Intrinsic Activating Properties of GP IIb/IIIa Blockers  Academic Article
• Isoform-specific effects of protein phosphatase 1 on outside-in signalling of integrin αIIbβ3: A story told by genetic manipulation of platelet surrogate cells  Comment
• Literatur zum Artikel: Schwarz  Academic Article
• Magnetic Resonance Imaging Contrast Agent Targeted Toward Activated Platelets Allows In Vivo Detection of Thrombosis and Monitoring of Thrombolysis  Academic Article
• Molecular Magnetic Resonance Imaging Allows the Detection of Activated Platelets in a New Mouse Model of Coronary Artery Thrombosis  Academic Article
• Novel Thrombolytic Drug Based on Thrombin Cleavable Microplasminogen Coupled to a Single‐Chain Antibody Specific for Activated GPIIb/IIIa  Academic Article
• PI 3-kinase p110β: a new target for antithrombotic therapy  Academic Article
• Platelet Function During and After Thrombolytic Therapy for Acute Myocardial Infarction With Reteplase, Alteplase, or Streptokinase  Academic Article
• Platelet Glycoprotein IIb/IIIa Receptor Blockade and Low-Dose Heparin during Percutaneous Coronary Revascularization  Academic Article
• Platelet activation as a potential mechanism of GP IIb/IIIa inhibitor-induced thrombocytopenia  Academic Article
• Platelet receptors as therapeutic targets: Past, present and future  Academic Article
• Platelet-targeted delivery of peripheral blood mononuclear cells to the ischemic heart restores cardiac function after ischemia-reperfusion injury  Academic Article
• Reversibility versus Persistence of GPIIb/IIIa Blocker-Induced Conformational Change of GPIIb/IIIa (αIIbβ3, CD41/CD61)  Academic Article
• Roles of Mac-1 and glycoprotein IIb/IIIa integrins in leukocyte–platelet aggregate formation: Stabilization by Mac-1 and inhibition by GpIIb/IIIa blockers  Academic Article
• Selective inhibition of the platelet phosphoinositide 3-kinase p110β as promising new strategy for platelet protection during extracorporeal circulation  Academic Article
• Short-acting P 2 Y 12 blockade to reduce platelet dysfunction and coagulopathy during experimental extracorporeal circulation and hypothermia  Academic Article
• Single-chain antibodies for the conformation-specific blockade of activated platelet integrin αIIbβ3 designed by subtractive selection from naive human phage libraries  Academic Article
• Targeted Antithrombotic Protein Micelles  Academic Article
• Targeting Ligand-Induced Binding Sites on GPIIb/IIIa via Single-Chain Antibody Allows Effective Anticoagulation Without Bleeding Time Prolongation  Academic Article
• Targeting activated platelets: A unique and potentially universal approach for cancer imaging  Academic Article
• Targeting the Platelet Integrin GPIIb/IIIa  Academic Article
• The GP IIb/IIIa inhibitor abciximab (c7E3) inhibits the binding of various ligands to the leukocyte integrin Mac-1 (CD11b/CD18, αMβ2)  Academic Article
• Therapeutic integrin inhibition: Allosteric and activation-specific inhibition strategies may surpass the initial ligand-mimetic strategies  Academic Article
• Therapeutische Inhibition von Thrombozyten im akuten Koronarsyndrom und bei Koronarintervention: Mechanismen und klinische Ergebnisse  Academic Article
• Use of GPIIb/IIIa inhibitors in cardiovascular medicine  Academic Article
• Visualization of Activated Platelets by Targeted Magnetic Resonance Imaging Utilizing Conformation-Specific Antibodies against Glycoprotein IIb/IIIa  Academic Article