Platelet Glycoprotein GPIIb-IIIa Complex
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A Mechanistic Model for Paradoxical Platelet Activation by Ligand-Mimetic αIIbβ3(GPIIb/IIIa) Antagonists Academic Article
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A deletion in the ?? subunit locks platelet integrin ??IIb??3 into a high affinity state Academic Article
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A single-chain antibody-CD39 fusion protein targeting activated platelets protects from cardiac ischaemia/reperfusion injury Academic Article
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Abciximab, Eptifibatide, and Tirofiban Exhibit Dose-dependent Potencies to Dissolve Platelet Aggregates Academic Article
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Activated platelets in the tumor microenvironment for targeting of antibody-drug conjugates to tumors and metastases Academic Article
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Activating Effects of GPIIb/IIIa Blockers: An Intrinsic Consequence of Ligand- Mimetic Properties Academic Article
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An Activation-Specific Platelet Inhibitor That Can Be Turned On/Off by Medically Used Hypothermia Academic Article
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Celastrol, a Triterpene Extracted From Tripterygium wilfordii Hook F, Inhibits Platelet Activation Academic Article
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Conformation-Specific Blockade of the Integrin GPIIb/IIIa Academic Article
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Critical temperature ranges of hypothermia-induced platelet activation: Possible implications for cooling patients in cardiac surgery Academic Article
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Delayed targeting of CD39 to activated platelet GPIIb/IIIa via a single-chain antibody: breaking the link between antithrombotic potency and bleeding? Academic Article
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Distinct roles of ligand affinity and cytoskeletal anchorage in αIIbβ3(GP IIb/IIIa)-mediated cell aggregation and adhesion Academic Article
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Dual targeting improves capture of ultrasound microbubbles towards activated platelets but yields no additional benefit for imaging of arterial thrombosis Academic Article
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Dual-contrast molecular imaging allows noninvasive characterization of myocardial ischemia/reperfusion injury after coronary vessel occlusion in mice by magnetic resonance imaging Academic Article
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Effects of different thrombolytic treatment regimen with abciximab and tirofiban on platelet aggregation and platelet-leukocyte interactions: A subgroup analysis from the GUSTO V and FASTER trials Academic Article
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Evidence for a differential functional regulation of the two β3-integrins αVβ3 and αIIbβ3 Academic Article
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Flow Cytometric Monitoring of Glycoprotein IIb/IIIa Blockade and Platelet Function in Patients With Acute Myocardial Infarction Receiving Reteplase, Abciximab, and Ticlopidine Academic Article
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Forget about thrombosis: Platelets and Alzheimer’s disease, yet another sticky situation Academic Article
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Functionalized Magnetic Resonance Contrast Agent Selectively Binds to Glycoprotein IIb/IIIa on Activated Human Platelets under Flow Conditions and Is Detectable at Clinically Relevant Field Strengths Academic Article
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GPIIb/IIIa inhibitors: From bench to bedside and back to bench again Academic Article
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GPIIb/IIIa-Blockade zur Optimierung der Thrombolyse bei aktuem Myokardinfarkt Academic Article
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Genetic transfer of fusion proteins effectively inhibits VCAM-1-mediated cell adhesion and transmigration via inhibition of cytoskeletal anchorage Academic Article
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Highly Sensitive Detection of Minimal Cardiac Ischemia using Positron Emission Tomography Imaging of Activated Platelets Academic Article
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Human IgG Monoclonal Anti-αIIbβ3-Binding Fragments Derived from Immunized Donors Using Phage Display Academic Article
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Improving selection of αIIbβ3-binding phage antibodies with increased reactivity derived from immunized donors Academic Article
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Induction of Fibrinogen Binding and Platelet Aggregation as a Potential Intrinsic Property of Various Glycoprotein IIb/IIIa (IIbβ3) Inhibitors Academic Article
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Inhaled Nitric Oxide Inhibits Human Platelet Aggregation, P-Selectin Expression, and Fibrinogen Binding In Vitro and In Vivo Academic Article
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Inhibition of platelet activation and aggregation Academic Article
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Integrin cytoplasmic domains mediate inside-out signal transduction Academic Article
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Intrinsic Activating Properties of GP IIb/IIIa Blockers Academic Article
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Isoform-specific effects of protein phosphatase 1 on outside-in signalling of integrin αIIbβ3: A story told by genetic manipulation of platelet surrogate cells Comment
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Literatur zum Artikel: Schwarz Academic Article
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Magnetic Resonance Imaging Contrast Agent Targeted Toward Activated Platelets Allows In Vivo Detection of Thrombosis and Monitoring of Thrombolysis Academic Article
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Molecular Magnetic Resonance Imaging Allows the Detection of Activated Platelets in a New Mouse Model of Coronary Artery Thrombosis Academic Article
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Novel Thrombolytic Drug Based on Thrombin Cleavable Microplasminogen Coupled to a Single‐Chain Antibody Specific for Activated GPIIb/IIIa Academic Article
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PI 3-kinase p110β: a new target for antithrombotic therapy Academic Article
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Platelet Function During and After Thrombolytic Therapy for Acute Myocardial Infarction With Reteplase, Alteplase, or Streptokinase Academic Article
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Platelet activation as a potential mechanism of GP IIb/IIIa inhibitor-induced thrombocytopenia Academic Article
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Platelet receptors as therapeutic targets: Past, present and future Academic Article
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Platelet-targeted delivery of peripheral blood mononuclear cells to the ischemic heart restores cardiac function after ischemia-reperfusion injury Academic Article
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Platelet–Leukocyte–Endothelial Cell Interactions after Middle Cerebral Artery Occlusion and Reperfusion Academic Article
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Reversibility versus Persistence of GPIIb/IIIa Blocker-Induced Conformational Change of GPIIb/IIIa (αIIbβ3, CD41/CD61) Academic Article
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Roles of Mac-1 and glycoprotein IIb/IIIa integrins in leukocyte–platelet aggregate formation: Stabilization by Mac-1 and inhibition by GpIIb/IIIa blockers Academic Article
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Selective inhibition of the platelet phosphoinositide 3-kinase p110β as promising new strategy for platelet protection during extracorporeal circulation Academic Article
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Short-acting P 2 Y 12 blockade to reduce platelet dysfunction and coagulopathy during experimental extracorporeal circulation and hypothermia Academic Article
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Single‐chain antibodies for the conformation‐specific blockade of activated platelet integrin α
IIb
β
3
designed by subtractive selection from naïve human phage libraries Academic Article
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Successful Renal Denervation Decreases the Platelet Activation Status in Hypertensive Patients. Academic Article
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Targeted Antithrombotic Protein Micelles Academic Article
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Targeting Ligand-Induced Binding Sites on GPIIb/IIIa via Single-Chain Antibody Allows Effective Anticoagulation Without Bleeding Time Prolongation Academic Article
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Targeting activated platelets: A unique and potentially universal approach for cancer imaging Academic Article
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Targeting the Platelet Integrin GPIIb/IIIa Academic Article
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The GP IIb/IIIa inhibitor abciximab (c7E3) inhibits the binding of various ligands to the leukocyte integrin Mac-1 (CD11b/CD18, αMβ2) Academic Article
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Therapeutic integrin inhibition: Allosteric and activation-specific inhibition strategies may surpass the initial ligand-mimetic strategies Academic Article
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Therapeutische Inhibition von Thrombozyten im akuten Koronarsyndrom und bei Koronarintervention: Mechanismen und klinische Ergebnisse Academic Article
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Use of GPIIb/IIIa inhibitors in cardiovascular medicine Academic Article
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Usefulness of Transient and Persistent No Reflow to Predict Adverse Clinical Outcomes Following Percutaneous Coronary Intervention Academic Article
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Visualization of Activated Platelets by Targeted Magnetic Resonance Imaging Utilizing Conformation-Specific Antibodies against Glycoprotein IIb/IIIa Academic Article