subject area of

• A novel valproic acid prodrug as an anticancer agent that enhances doxorubicin anticancer activity and protects normal cells against its toxicity in vitro and in vivo  Academic Article
• Activation of Adriamycin by the pH-dependent formaldehyde-releasing prodrug hexamethylenetetramine  Academic Article
• Activation of clinically used anthracyclines by the formaldehyde-releasing prodrug pivaloyloxymethyl butyrate  Academic Article
• Anticancer prodrugs of butyric acid and formaldehyde protect against doxorubicin-induced cardiotoxicity  Academic Article
• Development of Pluronic Micelle-Encapsulated Doxorubicin and Formaldehyde-Releasing Prodrugs for Localized Anticancer Chemotherapy  Academic Article
• Effects of histone deacetylase inhibitory prodrugs on epigenetic changes and DNA damage response in tumor and heart of glioblastoma xenograft  Academic Article
• Evidence that the MEK/ERK but not the PI3K/Akt pathway is required for protection from myocardial ischemia-reperfusion injury by 3',4'-dihydroxyflavonol  Academic Article
• Formaldehyde-Releasing Prodrugs in Combination With Adriamycin Can Overcome Cellular Drug Resistance  Academic Article
• Formaldehyde-releasing prodrugs specifically affect cancer cells by depletion of intracellular glutathione and augmentation of reactive oxygen species  Academic Article
• In vivo andin vitro antitumor activity of butyroyloxymethyl-diethyl phosphate (AN-7), a histone deacetylase inhibitor, in human prostate cancer  Academic Article
• Mode of interaction between butyroyloxymethyl-diethyl phosphate (AN-7) and doxorubicin in MCF-7 and resistant MCF-7/Dx cell lines  Academic Article
• Molecular basis for the synergistic interaction of Adriamycin with the formaldehyde-releasing prodrug pivaloyloxymethyl butyrate (AN-9)  Academic Article
• New Anthracenedione Derivatives with Improved Biological Activity by Virtue of Stable Drug−DNA Adduct Formation  Academic Article
• Potent Inhibitors of Phosphatidylinositol 3 (PI3) Kinase that have Antiproliferative Activity Only When Delivered as Prodrug Forms  Academic Article
• Protease-responsive prodrug with aggregation-induced emission probe for controlled drug delivery and drug release tracking in living cells  Academic Article
• The Power and Potential of Doxorubicin-DNA Adducts  Academic Article
• The Role of Intracellularly Released Formaldehyde and Butyric Acid in the Anticancer Activity of Acyloxyalkyl Esters  Academic Article
• The selectivty and anti-metastatic activity of oral bioavailable butyric acid prodrugs  Academic Article