subject area of

• A Family of Leukemia Inhibitory Factor-Binding Peptides that Can Act as Antagonists When Conjugated to Poly(ethylene glycol)†  Academic Article
• A Functional Interaction between CD46 and DLG4  Academic Article
• A GTPase Chimera Illustrates an Uncoupled Nucleotide Affinity and Release Rate, Providing Insight into the Activation Mechanism  Academic Article
• A Malaria Parasite Formin Regulates Actin Polymerization and Localizes to the Parasite-Erythrocyte Moving Junction during Invasion  Academic Article
• A Molecular Switch Governs the Interaction between the Human Complement Protease C1s and Its Substrate, Complement C4  Academic Article
• A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production  Academic Article
• A SAM oligomerization domain shapes the genomic binding landscape of the LEAFY transcription factor  Academic Article
• A Single β-Amino Acid Substitution to Angiotensin II Confers AT 2 Receptor Selectivity and Vascular Function  Academic Article
• A Structural Investigation of NRZ Mediated Apoptosis Regulation in Zebrafish  Academic Article
• A class of highly selective inhibitors bind to an active state of PI3K gamma  Academic Article
• A comparative study between the adsorption and covalent binding of human immunoglobulin and lysozyme on surface-modified poly( tert -butyl methacrylate)  Academic Article
• A domain level interaction network of amyloid precursor protein and Aβ of Alzheimer's disease  Academic Article
• A functional genomics catalogue of activated transcription factors during pathogenesis of pneumococcal disease  Academic Article
• A major binding protein for leukemia inhibitory factor in normal mouse serum: identification as a soluble form of the cellular receptor.  Academic Article
• A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR  Academic Article
• A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin  Academic Article
• A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells.  Academic Article
• A neural network model approach to the study of human TAP transporter.  Academic Article
• A newly discovered protein export machine in malaria parasites  Academic Article
• A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation  Academic Article
• A novel molecular mechanism to explain biotin-unresponsive holocarboxylase synthetase deficiency  Academic Article
• A novel role for the pol I transcription factor ubtf in maintaining genome stability through the regulation of highly transcribed pol II genes  Academic Article
• A pharmacological study of NLP-12 neuropeptide signaling in free-living and parasitic nematodes  Academic Article
• A phototaxis signalling complex in Dictyostelium discoideum  Academic Article
• A presequence- and voltage-sensitive channel of the mitochondrial preprotein translocase formed by Tim23  Academic Article
• A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis  Academic Article
• A steered molecular dynamics mediated hit discovery for histone deacetylases  Academic Article
• A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition  Academic Article
• Accumulation of Non-Transferrin-Bound Iron by Neurons, Astrocytes, and Microglia  Academic Article
• Acetylation of VGLL4 Regulates Hippo-YAP Signaling and Postnatal Cardiac Growth  Academic Article
• Activated Platelets in Carotid Artery Thrombosis in Mice Can Be Selectively Targeted with a Radiolabeled Single-Chain Antibody  Academic Article
• Activation of protease-activated receptors by gingipains fromPorphyromonas gingivalis leads to platelet aggregation: a new trait in microbial pathogenicity  Academic Article
• Acute myeloid leukemia requires Hhex to enable PRC2-mediated epigenetic repression ofCdkn2a  Academic Article
• Adaptor protein controlled oligomerization activates the AAA+ protein ClpC  Academic Article
• An Electrostatic Model with Weak Actin-Myosin Attachment Resolves Problems with the Lattice Stability of Skeletal Muscle  Academic Article
• An FcγRIIa-binding peptide that mimics the interaction between FcγRIIa and IgG  Academic Article
• An antagonist of the platelet-activating factor receptor inhibits adherence of both nontypeable Haemophilus influenzae and Streptococcus pneumoniae to cultured human bronchial epithelial cells exposed to cigarette smoke  Academic Article
• An optimized hepatitis C virus E2 glycoprotein core adopts a functional homodimer that efficiently blocks virus entry  Academic Article
• Analysis of Fasciola cathepsin L5 by S2 subsite substitutions and determination of the P1–P4 specificity reveals an unusual preference  Academic Article
• Anionic Phospholipid Interactions of the Prion Protein N Terminus Are Minimally Perturbing and Not Driven Solely by the Octapeptide Repeat Domain  Academic Article
• Antagonism of Antiviral and Allogeneic Activity of a Human Public CTL Clonotype by a Single Altered Peptide Ligand: Implications for Allograft Rejection  Academic Article
• Antibodies binding the ADAM10 substrate recognition domain inhibit Eph function  Academic Article
• Antibody Recognition of Disordered Antigens  Academic Article
• Anticonvulsant Met-Enkephalin Analogues Containing Backbone Spacers Reveal Alternative Non-Opioid Signaling in the Brain  Academic Article
• Antigen Ligation Triggers a Conformational Change within the Constant Domain of the αβ T Cell Receptor  Academic Article
• Antithrombins Wibble and Wobble (T85M/K): Archetypal Conformational Diseases With In Vivo Latent-Transition, Thrombosis, and Heparin Activation  Academic Article
• Apical Membrane Antigen 1 as an Anti-Malarial Drug Target  Academic Article
• Apoptosis inhibitor 5 is an endogenous inhibitor of caspase‐2  Academic Article
• Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax  Academic Article
• Apoptosis: A sticky business  Academic Article
• Arabidopsis basic helix-loop-helix transcription factors MYC2,MYC3, andMYC4 regulate glucosinolate biosynthesis, insect performance, and feeding behavior  Academic Article
• Aromatic Anchor at an Invariant Hormone-Receptor Interface FUNCTION OF INSULIN RESIDUE B24 WITH APPLICATION TO PROTEIN DESIGN  Academic Article
• Aspartyl Protease Inhibitor Pepstatin Binds to the Presenilins of Alzheimer's Disease†  Academic Article
• Assembly of the Type II Secretion System such as Found in Vibrio cholerae Depends on the Novel Pilotin AspS  Academic Article
• Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation  Academic Article
• Association of the Novel Non-AT1, Non-AT2 Angiotensin Binding Site with Neuronal Cell Death  Academic Article
• Asymmetric Recruitment of cIAPs by TRAF2  Academic Article
• Ataxin-2 interacts with FUS and intermediate-length polyglutamine expansions enhance FUS-related pathology in amyotrophic lateral sclerosis  Academic Article
• Avoidance of self-reactivity results in skewed CTL responses to rare components of synthetic immunogens  Academic Article
• Avoiding the oligomeric state: αB-crystallin inhibits fragmentation and induces dissociation of apolipoprotein C-II amyloid fibrils  Academic Article
• BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals  Academic Article
• Bcl-2, Bcl-x L, and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells  Academic Article
• Becoming a peroxidase: Cardiolipin-induced unfolding of cytochrome c  Academic Article
• Bicarbonate-Mediated Stimulation of RegA, the Global Virulence Regulator from Citrobacter rodentium  Academic Article
• Bim must be able to engage all pro-survival Bcl-2 family members for efficient tumor suppression  Comment
• Binding Inhibitors of the Bacterial Sliding Clamp by Design  Academic Article
• Biochemical and Structural Insights into Doublecortin-like Kinase Domain 1  Academic Article
• Bioinformatics tools and resources for analyzing protein structures  Chapter
• Bmf: A Proapoptotic BH3-Only Protein Regulated by Interaction with the Myosin V Actin Motor Complex, Activated by Anoikis  Academic Article
• Buffy, a Drosophila Bcl-2 protein, has anti-apoptotic and cell cycle inhibitory functions  Academic Article
• Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells.  Academic Article
• CD1d-lipid antigen recognition by the γδ TCR.  Academic Article
• CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence  Academic Article
• CR1/CR2 Interactions Modulate the Functions of the Cell Surface Epidermal Growth Factor Receptor  Academic Article
• Calcium-dependent Open/Closed Conformations and Interfacial Energy Maps of Reconstituted Hemichannels  Academic Article
• Calcium-dependent oligomerization of CAR proteins at cell membrane modulates ABA signaling  Academic Article
• Calmodulin interacts with MLO protein to regulate defence against mildew in barley  Academic Article
• Calmodulin-dependent nuclear import of HMG-box family nuclear factors: importance of the role of SRY in sex reversal  Academic Article
• Casein kinase II phosphorylation of cyclin F at serine 621 regulates the Lys48-ubiquitylation E3 ligase activity of the SCF (cyclin F) complex  Academic Article
• Cell Surface-expressed Cation-independent Mannose 6-Phosphate Receptor (CD222) Binds Enzymatically Active Heparanase Independently of Mannose 6-Phosphate to Promote Extracellular Matrix Degradation  Academic Article
• Cell death regulation by the mammalian IAP antagonist Diablo/Smac  Academic Article
• Changes at peptide residues buried in the major histocompatibility complex (MHC) class I binding cleft influence T cell recognition: a possible role for indirect conformational alterations in the MHC class I or bound peptide in determining T cell recognition.  Academic Article
• Characterization of ABT-806, a humanized tumor-specific anti-EGFR monoclonal antibody  Academic Article
• Characterization of a Large Chondroitin Sulfate Proteoglycan Present in Bovine Collateral Ligament  Academic Article
• Characterization of a novel JNK (c-Jun N-terminal kinase) inhibitory peptide  Academic Article
• Characterization of monomeric dihydrodipicolinate synthase variant reveals the importance of substrate binding in optimizing oligomerization  Academic Article
• Characterization of the DsbA Oxidative Folding Catalyst fromPseudomonas aeruginosaReveals a Highly Oxidizing Protein that Binds Small Molecules  Academic Article
• Characterization of the Specificity of Arginine-Specific Gingipains fromPorphyromonas gingivalisReveals Active Site Differences between Different Forms of the Enzymes†  Academic Article
• Characterization of the binding activities of proteinase-adhesin complexes from Porphyromonas gingivalis.  Academic Article
• Cholesterol and anionic phospholipids increase the binding of amyloidogenic transthyretin to lipid membranes  Academic Article
• Chtop (Chromatin target of Prmt1) auto-regulates its expression level via intron retention and nonsense-mediated decay of its own mRNA  Academic Article
• ClpS, a Substrate Modulator of the ClpAP Machine  Academic Article
• Comparative aspects of the calcium-sensitive photoproteins aequorin and obelin  Academic Article
• Compartmentalized MHC class I antigen processing enhances immunosurveillance by circumventing the law of mass action  Academic Article
• Complement component 1, q subcomponent binding protein is a marker for proliferation in breast cancer  Academic Article
• Complete amino acid analysis of proteins from a single hydrolysate  Academic Article
• Complexes of gastrin with In3+, Ru3+ or Ga3+ ions are not recognised by the cholecystokinin 2 receptor  Academic Article
• Conformational Changes in Bcl-2 Pro-survival Proteins Determine Their Capacity to Bind Ligands  Academic Article
• Conformational changes in serpins: II. the mechanism of activation of antithrombin by heparin  Academic Article
• Conservation of a Glycine-rich Region in the Prion Protein Is Required for Uptake of Prion Infectivity  Academic Article
• Conservation of the ST6Gal I gene and its expression in the mammary gland  Academic Article
• Construction and characterization of a recombinant plasminogen activator composed of an anti-fibrin single-chain antibody and low-molecular-weight urokinase  Academic Article
• Controls and constrains of the membrane disrupting action of Aurein 1.2  Academic Article
• Conversion of Bim-BH3 from activator to inhibitor of Bak through structure-based design  Academic Article
• Crystal Structure and Comparative Functional Analyses of a Mycobacterium Aldo-Keto Reductase  Academic Article
• Crystal Structure of a BCL-W Domain-Swapped Dimer: Implications for the Function of BCL-2 Family Proteins  Academic Article
• Crystal Structure of a Soluble Form of the Intracellular Chloride Ion Channel CLIC1 (NCC27) at 1.4-Å Resolution  Academic Article
• Crystal structure of PfRh5, an essential P. falciparum ligand for invasion of human erythrocytes  Academic Article
• Crystal structure of bacterial succinate:quinone oxidoreductase flavoprotein SdhA in complex with its assembly factor SdhE  Academic Article
• Crystal structure of fuculose aldolase from the Antarctic psychrophilic yeast Glaciozyma antarctica PI12  Academic Article
• Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser  Academic Article
• Crystal structure of the human Scribble PDZ1 domain bound to the PDZ-binding motif of APC  Academic Article
• Crystal structure of the human T cell receptor CD3   heterodimer complexed to the therapeutic mAb OKT3  Academic Article
• Crystal structure of the human leukocyte Fc receptor, FcγRIIa  Academic Article
• Crystallization and preliminary X-ray analysis of theEscherichia coliadaptor protein ClpS, free and in complex with the N-terminal domain of ClpA  Academic Article
• Crystallization of FLINC4, an intramolecular LMO4–ldb1 complex  Academic Article
• Crystallization of a paraspeckle protein PSPC1–NONO heterodimer  Academic Article
• Crystallographic Insight into Collagen Recognition by Discoidin Domain Receptor 2  Academic Article
• Cucumber Mosaic Virus 2b Protein Subcellular Targets and Interactions: Their Significance to RNA Silencing Suppressor Activity  Academic Article
• Cyclic‐AMP‐dependent protein kinase A regulates apoptosis by stabilizing the BH3‐only protein Bim  Academic Article
• Cytokinin response factor 6 represses cytokinin-associated genes during oxidative stress  Academic Article
• DHA prevents altered 5-HT1A, 5-HT2A, CB1 and GABAA receptor binding densities in the brain of male rats fed a high-saturated-fat diet  Academic Article
• DNA Accelerates the Inhibition of Human Cathepsin V by Serpins  Academic Article
• Debcl, a Proapoptotic Bcl-2 Homologue, Is a Component of the Drosophila melanogaster Cell Death Machinery  Academic Article
• Deerpox Virus Encodes an Inhibitor of Apoptosis That Regulates Bak and Bax  Academic Article
• Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis  Academic Article
• Design and testing of bicyclic inhibitors of Grb7-are two cycles better than one?  Academic Article
• Design principles of peptide based self-assembled nanomaterials  Chapter
• Determination and inference of eukaryotic transcription factor sequence specificity  Academic Article
• Determination of ligand binding modes in weak protein–ligand complexes using sparse NMR data  Academic Article
• Determining the Subcellular Location of Synthesis and Assembly of the Cell Wall Polysaccharide (1,3; 1,4)-β-d-Glucan in Grasses  Academic Article
• Differences in the binding capacity of human apolipoprotein E3 and E4 to size-fractionated lipid emulsions  Academic Article
• Differential Centrifugation Separates Cardiac Sarcolemmal and Endosomal Membranes from Langendorff-Perfused Rat Hearts  Academic Article
• Differential Inhibition of TRAIL-Mediated DR5-DISC Formation by Decoy Receptors 1 and 2  Academic Article
• Differential and synergistic effects of epidermal growth factor receptor antibodies on unliganded ErbB dimers and oligomers  Academic Article
• Dihydroorotase from Escherichia coli: Loop Movement and Cooperativity between Subunits  Academic Article
• Discordant Regulation of Granzyme H and Granzyme B Expression in Human Lymphocytes  Academic Article
• Disruption of prion protein-HOP engagement impairs glioblastoma growth and cognitive decline and improves overall survival  Academic Article
• Disruption of the Disulfide Bonds of Recombinant Murine Interleukin-6 Induces Formation of a Partially Unfolded State†  Academic Article
• Distinct activation modes of the Relaxin Family Peptide Receptor 2 in response to insulin-like peptide 3 and relaxin  Academic Article
• Distinct roles of ligand affinity and cytoskeletal anchorage in αIIbβ3(GP IIb/IIIa)-mediated cell aggregation and adhesion  Academic Article
• Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide  Academic Article
• Domain One of the High Affinity IgE Receptor, FcεRI, Regulates Binding to IgE through Its Interface with Domain Two  Academic Article
• Dopamine D1 receptor binding in the anterior cingulate cortex of patients with obsessive–compulsive disorder  Academic Article
• Dose-Dependent Effects of the Myosin Activator Omecamtiv Mecarbil on Cross-Bridge Behavior and Force Generation in Failing Human Myocardium  Academic Article
• Drosophila melanogaster Guk-holder interacts with the Scribbled PDZ1 domain and regulates epithelial development with Scribbled and Discs Large  Academic Article
• Drug-resistant mutants of chinese hamster ovary cells possess an altered cell surface carbohydrate component  Academic Article
• Dynamic modelling reveals 'hotspots' on the pathway to enzyme-substrate complex formation  Academic Article
• E2F1 Binds to the Peptide-Binding Groove within the BIR3 Domain of cIAP1 and Requires cIAP1 for Chromatin Binding  Academic Article
• ETHYLENE RESPONSE FACTOR 74 (ERF74) plays an essential role in controlling a respiratory burst oxidase homolog D (RbohD)-dependent mechanism in response to different stresses in Arabidopsis  Academic Article
• Effect of Structural Stress on the Flexibility and Adaptability of HIV-1 Protease  Academic Article
• Effect of a Broad-Specificity Chemokine-Binding Protein on Brain Leukocyte Infiltration and Infarct Development  Academic Article
• Effects of Mutations in the Cytoplasmic Domain of Integrin β1 to Talin Binding and Cell Spreading  Academic Article
• Efficient discovery of immune response targets by cyclical refinement of QSAR models of peptide binding  Academic Article
• Egalitarian binds dynein light chain to establish oocyte polarity and maintain oocyte fate  Academic Article
• Energy based pharmacophore mapping of HDAC inhibitors against class I HDAC enzymes  Academic Article
• Engineering the Biointerface of Electrospun 3D Scaffolds with Functionalized Polymer Brushes for Enhanced Cell Binding  Academic Article
• Eph/Ephrin Signalling and Function in Oncogenesis: Lessons from Embryonic Development  Academic Article
• Evolution of Serpin Specificity: Cooperative Interactions in the Reactive-Site Loop Sequence of Antithrombin Specifically Restrict the Inhibition of Activated Protein C  Academic Article
• Exceptionally high conservation of the MHC class I-related gene, MR1, among mammals  Academic Article
• Exploring ligand recognition, selectivity and dynamics of TPR domains of chloroplast Toc64 and mitochondria Om64 from Arabidopsis thaliana  Academic Article
• Exploring the correlation between the sequence composition of the nucleotide binding G5 loop of the FeoB GTPase domain (NFeoB) and intrinsic rate of GDP release  Academic Article
• Export of malaria proteins requires co-translational processing of the PEXEL motif independent of phosphatidylinositol-3-phosphate binding  Academic Article
• Expression of the MAGE-1 gene in human hepatocellular carcinomas  Academic Article
• Extending Halogen-based Medicinal Chemistry to Proteins IODO-INSULIN AS A CASE STUDY  Academic Article
• Fine Structure Analysis of Interaction of FcεRI with IgE  Academic Article
• Fluorescence and analytical ultracentrifugation analyses of the interaction of the tyrosine kinase inhibitor, tyrphostin AG1478-mesylate, with albumin  Academic Article
• Formation of dopamine-mediated α-synuclein-soluble oligomers requires methionine oxidation  Academic Article
• Functional Analysis of Human Metaxin in Mitochondrial Protein Import in Cultured Cells and Its Relationship with the Tom Complex  Academic Article
• Functional Analysis of Human Mitochondrial Receptor Tom20 for Protein Import into Mitochondria  Academic Article
• Functional Definition of Outer Membrane Proteins Involved in Preprotein Import into Mitochondria  Academic Article
• Functional characterization of an eosinophil-specific galectin, ovine galectin-14  Academic Article
• Functional interaction between the ZO-1-interacting transcription factor ZONAB/DbpA and the RNA processing factor symplekin  Academic Article
• Functional role of soluble receptor for advanced glycation end products in stroke  Academic Article
• Galectin-11: A novel host mediator targeting specific stages of the gastrointestinal nematode parasite, Haemonchus contortus  Academic Article
• Gel chromatographic procedure that corrects for Donnan effects in studies of ligand binding. Its application to the interaction of copper ions with bovine serum albumin and deoxyribonucleic acid  Academic Article
• Genomic and functional characterization of the oas gene family encoding O-acetylserine (thiol) lyases, enzymes catalyzing the final step in cysteine biosynthesis in Arabidopsis thaliana  Academic Article
• Gingipain enzymes fromPorphyromonas gingivalispreferentially bind immobilized extracellular proteins: a mechanism favouring colonization?  Academic Article
• Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) induces cancer cell senescence by interacting with telomerase RNA component  Academic Article
• Glycoprotein VI is associated with GPIb-IX-V on the membrane of resting and activated platelets  Academic Article
• Green fluorescent antibodies: novel in vitro tools  Academic Article
• HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi  Academic Article
• High-Resolution Structural Characterization of a Helical α/β-Peptide Foldamer Bound to the Anti-Apoptotic Protein Bcl-xL  Academic Article
• High-Resolution Structures of Human Aldose Reductase Holoenzyme in Complex with Stereoisomers of the Potent Inhibitor Fidarestat:  Stereospecific Interaction between the Enzyme and a Cyclic Imide Type Inhibitor  Academic Article
• High-affinity Cyclic Peptide Matriptase Inhibitors  Academic Article
• High-resolution crystal structure of the reduced Grx1 from Saccharomyces cerevisiae  Academic Article
• Higher-Resolution Structure of the Human Insulin Receptor Ectodomain: Multi-Modal Inclusion of the Insert Domain  Academic Article
• Hippocampal 5-HT 1A receptor binding is related to object–location memory in humans  Academic Article
• Histidine-rich Glycoprotein Binds to Cell-surface Heparan Sulfate via Its N-terminal Domain following Zn2+ Chelation  Academic Article
• Histidine-rich Glycoprotein Specifically Binds to Necrotic Cells via Its Amino-terminal Domain and Facilitates Necrotic Cell Phagocytosis  Academic Article
• Histidine-rich glycoprotein binds heparanase and regulates its enzymatic activity and cell surface interactions  Academic Article
• Histidine-rich glycoprotein functions cooperatively with cell surface heparan sulfate on phagocytes to promote necrotic cell uptake  Academic Article
• How insulin engages its primary binding site on the insulin receptor  Academic Article
• HtrA2/Omi, a Sheep in Wolf's Clothing  Academic Article
• Human Bcl-2 cannot directly inhibit the Caenorhabditis elegans Apaf-1 homologue CED-4, but can interact with EGL-1  Academic Article
• Human CIA30 is involved in the early assembly of mitochondrial complex I and mutations in its gene cause disease  Academic Article
• Human beta-defensin 2 kills Candida albicans through phosphatidylinositol 4,5-bisphosphate-mediated membrane permeabilization  Academic Article
• IAP et Rho : enfin connectées  Academic Article
• IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-κB as well as cell survival and oncogenesis  Academic Article
• IAPs – the ubiquitin connection  Academic Article
• Identification of PLP2 and RAB5C as novel TPD52 binding partners through yeast two-hybrid screening  Academic Article
• Identification of a Wnt-induced protein complex by affinity proteomics using an antibody that recognizes a sub-population of β-catenin  Academic Article
• Identification of an activation site in Bak and mitochondrial Bax triggered by antibodies  Academic Article
• Identification of canary grass (Phalaris aquatica) pollen allergens by immunoblotting: IgE and IgG antibody-binding studies  Academic Article
• Identification of mammalian mitochondrial proteins that interact with IAPs via N-terminal IAP binding motifs  Academic Article
• Identification of residues in the first domain of human Fcα receptor essential for interaction with IgA  Academic Article
• Identification of the Epitope for the Epidermal Growth Factor Receptor-specific Monoclonal Antibody 806 Reveals That It Preferentially Recognizes an Untethered Form of the Receptor  Academic Article
• Identification of the binding site of apical membrane antigen 1 (AMA1) inhibitors using a paramagnetic probe  Academic Article
• Identification, cloning and expression analysis of the pluripotency promoting Nanog genes in mouse and human  Academic Article
• Imatinib inhibits vascular smooth muscle proteoglycan synthesis and reduces LDL binding in vitro and aortic lipid deposition in vivo  Academic Article
• Immunochemical characterization of two thyroid-stimulating hormone β-subunit epitopes  Academic Article
• Importance of phosphoinositide binding by human beta-defensin 3 for Akt-dependent cytokine induction  Academic Article
• In situ phosphorylation of immobilized receptors on biosensor surfaces: Application to E-cadherin/β-catenin interactions  Academic Article
• In vivo evidence for cooperation of Mia40 and Erv1 in the oxidation of mitochondrial proteins  Academic Article
• Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin  Academic Article
• Induction of Fibrinogen Binding and Platelet Aggregation as a Potential Intrinsic Property of Various Glycoprotein IIb/IIIa (IIbβ3) Inhibitors  Academic Article
• Influence of Interleukin-6 (IL-6) Dimerization on Formation of the High Affinity Hexameric IL-6·Receptor Complex  Academic Article
• Influence of Size, Surface, Cell Line, and Kinetic Properties on the Specific Binding of A33 Antigen-Targeted Multilayered Particles and Capsules to Colorectal Cancer Cells  Academic Article
• Influences of temperature, oxidative stress, and phosphorylation on binding of heat shock proteins in skeletal muscle fibers  Academic Article
• Inhibiting Protein-Protein Interactions as an Emerging Paradigm for Drug Discovery  Academic Article
• Inhibition of Malaria Parasite Development by a Cyclic Peptide That Targets the Vital Parasite Protein SERA5  Academic Article
• Inhibition of established micrometastases by targeted drug delivery via cell surface-associated GRP78  Academic Article
• Inhibition of heat shock protein 70 blocks the development of cardiac hypertrophy by modulating the phosphorylation of histone deacetylase 2  Academic Article
• Inhibition of the all-trans Retinoic Acid (atRA) Hydroxylases CYP26A1 and CYP26B1 Results in Dynamic, Tissue-Specific Changes in Endogenous atRA Signaling  Academic Article
• Inhibition of the peroxidative degradation of haem as the basis of action of chloroquine and other quinoline antimalarials  Academic Article
• Insight into Schmid Metaphyseal Chondrodysplasia from the Crystal Structure of the Collagen X NC1 Domain Trimer  Academic Article
• Insight into the self-association of key enzymes from pathogenic species  Academic Article
• Insights into Duffy Binding-like Domains through the Crystal Structure and Function of the Merozoite Surface Protein MSPDBL2 fromPlasmodium falciparum  Academic Article
• Insights into the Immunological Properties of Intrinsically Disordered Malaria Proteins Using Proteome Scale Predictions  Academic Article
• Integrated activities of two alternative sigma factors coordinate iron acquisition and uptake by Pseudomonas aeruginosa  Academic Article
• Interaction of the Molecular Chaperone αB-Crystallin with α-Synuclein: Effects on Amyloid Fibril Formation and Chaperone Activity  Academic Article
• Interaction with PI3-kinase contributes to the cytotoxic activity of Apoptin  Academic Article
• Intrinsic Activating Properties of GP IIb/IIIa Blockers  Academic Article
• Investigation of the mechanism of interaction between Mannose-binding lectin-associated serine protease-2 and complement C4  Academic Article
• Investigations on the in vitro import ability of mitochondrial precursor proteins synthesized in wheat germ transcription-translation extract  Academic Article
• Isolation and characterization of an IgNAR variable domain specific for the human mitochondrial translocase receptor Tom70  Academic Article
• Isolation of transferrin from porcine gastric mucosa: Comparison with porcine serum transferrin  Academic Article
• KNAT7 Positively Regulates Xylan Biosynthesis by Directly Activating IRX9 Expression in Arabidopsis  Academic Article
• Kinetic and Crystallographic Analysis of MutantEscherichia coliAminopeptidase P:  Insights into Substrate Recognition and the Mechanism of Catalysis†  Academic Article
• Ligand Binding Determines Whether CD46 Is Internalized by Clathrin-coated Pits or Macropinocytosis  Academic Article
• Ligand Recognition by the TPR Domain of the Import Factor Toc64 from Arabidopsis thaliana  Academic Article
• Ligand binding induces a conformational change in epidermal growth factor receptor dimers  Academic Article
• Ligand-Induced Conformational Change of Plasmodium falciparum AMA1 Detected Using F-19 NMR  Academic Article
• Liver receptor homologue-1 expression in ovarian epithelial and granulosa cell tumours  Academic Article
• Localization of dynein light chains 1 and 2 and their pro-apoptotic ligands  Academic Article
• Mac-1 directly binds to the endothelial protein C-receptor: a link between the protein C anticoagulant pathway and inflammation?  Academic Article
• Mammalian initiator apoptotic caspases  Academic Article
• MecA, an adaptor protein necessary for ClpC chaperone activity  Academic Article
• Mechanism of intersubunit ketosynthase–dehydratase interaction in polyketide synthases  Academic Article
• Methods for sample labeling and meniscus determination in the fluorescence-detected analytical ultracentrifuge  Academic Article
• Methods to Measure the Kinetics of Protease Inhibition by Serpins  Academic Article
• MidA is a putative methyltransferase that is required for mitochondrial complex I function  Academic Article
• Minimal requirements for actin filament disassembly revealed by structural analysis of malaria parasite actin-depolymerizing factor 1  Academic Article
• Mitochondrial Presequence Translocase: Switching between TOM Tethering and Motor Recruitment Involves Tim21 and Tim17  Academic Article
• Mitochondrial matrix proteostasis is linked to hereditary paraganglioma: LON-mediated turnover of the human flavinylation factor SDH5 is regulated by its interaction with SDHA  Academic Article
• Mixed Lineage Kinase 2 Interacts with Clathrin and Influences Clathrin-coated Vesicle Trafficking  Academic Article
• Mixed-lineage kinase 2-SH3 domain binds dynamin and greatly enhances activation of GTPase by phospholipid  Academic Article
• Modification of PATase by L/F-transferase generates a ClpS-dependent N-end rule substrate in Escherichia coli  Academic Article
• Modified vaccinia virus Ankara protein F1L is a novel BH3-domain-binding protein and acts together with the early viral protein E3L to block virus-associated apoptosis  Academic Article
• Modulation of the proteolytic activity of the complement protease C1s by polyanions: implications for polyanion-mediated acceleration of interaction between C1s and SERPING1  Academic Article
• Modulation of voltage-gated K+ channels by the sodium channel  1 subunit  Academic Article
• Molecular Chaperones Hsp90 and Hsp70 Deliver Preproteins to the Mitochondrial Import Receptor Tom70  Academic Article
• Molecular Insights into the Interaction between Plasmodium falciparum Apical Membrane Antigen 1 and an Invasion-Inhibitory Peptide  Academic Article
• Molecular Structural Characteristics Important in Drug-HSA Binding  Academic Article
• Molecular and functional characterization of mouse signaling lymphocytic activation molecule (SLAM): Differential expression and responsiveness in Th1 and Th2 cells  Academic Article
• Molecular basis for the folding of β-helical autotransporter passenger domains  Academic Article
• Molecular basis of the cooperative binding of Cu(I) and Cu(II) to the CopK protein from Cupriavidus metallidurans CH34  Academic Article
• Molecular imaging of death receptor 5 occupancy and saturation kinetics in vivo by humanized monoclonal antibody CS-1008  Academic Article
• Molecular interaction between PHO2 and GIGANTEA reveals a new crosstalk between flowering time and phosphate homeostasis in Oryza sativa  Academic Article
• Monoclonal antibody 14C5 targets integrin  v 5  Academic Article
• Monoclonal antibody 806 inhibits the growth of tumor xenografts expressing either the de2-7 or amplified epidermal growth factor receptor (EGFR) but not wild-type EGFR  Academic Article
• Muc1 Mucin Limits Both Helicobacter pylori Colonization of the Murine Gastric Mucosa and Associated Gastritis  Academic Article
• Multi-tiered pairing selectivity between E2 ubiquitin–conjugating enzymes and E3 ligases  Academic Article
• Multifaceted effects of ATP on cardiolipin-bound cytochrome c  Academic Article
• Multiple Roles of Arabidopsis VRN1 in Vernalization and Flowering Time Control  Academic Article
• Multiple domains of MASP-2, an initiating complement protease, are required for interaction with its substrate C4.  Academic Article
• Multiple receptors converge on H2‐Q10 to regulate NK and γδT‐cell development  Academic Article
• Mutagenesis and selection of PDZ domains that bind new protein targets  Academic Article
• N-linked glycosylation modulates dimerization of protein disulfide isomerase family A member 2 (PDIA2)  Academic Article
• NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer’s models  Academic Article
• Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition  Academic Article
• Nedd4 family interacting protein 1 (Ndfip1) is required for ubiquitination and nuclear trafficking of BRCA1-associated ATM activator 1 (BRAT1) during the DNA damage response  Academic Article
• Negative regulation of gp130 signalling mediated through tyrosine-757 is not dependent on the recruitment of SHP2  Academic Article
• Neural network and SVM classifiers accurately predict lipid binding proteins, irrespective of sequence homology  Academic Article
• Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief  Academic Article
• New insights into the mechanism of dihydrodipicolinate synthase using isothermal titration calorimetry  Academic Article
• New layers in understanding and predicting α-linolenic acid content in plants using amino acid characteristics of omega-3 fatty acid desaturase  Academic Article
• New method for purifying histidine-rich glycoprotein from human plasma redefines its functional properties  Academic Article
• Nonlinear Predictive Modeling of MHC Class II-Peptide Binding Using Bayesian Neural Networks  Academic Article
• Novel Bcl-2 Homology-3 Domain-like Sequences Identified from Screening Randomized Peptide Libraries for Inhibitors of the Pro-survival Bcl-2 Proteins  Academic Article
• Novel Scabies Mite Serpins Inhibit the Three Pathways of the Human Complement System  Academic Article
• Novel monoclonal antibody specific for the de2-7 epidermal growth factor receptor (EGFR) that also recognizes the EGFR expressed in cells containing amplification of the EGFR gene  Academic Article
• Nuclear phosphoinositides could bring FYVE alive  Academic Article
• Nucleoprotein of influenza A virus is a major target of immunodominant CD8 + T‐cell responses  Academic Article
• On-Surface Aggregation of α-Synuclein at Nanomolar Concentrations Results in Two Distinct Growth Mechanisms  Academic Article
• Organization of Cytochrome P450 Enzymes Involved in Sex Steroid Synthesis  Academic Article
• PH1-derived bivalent bibodies and trivalent tribodies bind differentially to shed and tumour cell-associated MUC1  Academic Article
• POPS: A COMPUTATIONAL TOOL FOR MODELING AND PREDICTING PROTEASE SPECIFICITY  Academic Article
• POSH regulates Hippo signaling through ubiquitin-mediated expanded degradation  Academic Article
• PR55α-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity  Academic Article
• PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing  Academic Article
• PROSPER: An Integrated Feature-Based Tool for Predicting Protease Substrate Cleavage Sites  Academic Article
• PTP-PEST controls EphA3 activation and ephrin-induced cytoskeletal remodelling  Academic Article
• PYRABACTIN RESISTANCE1-LIKE8 plays an important role for the regulation of abscisic acid signaling in root  Academic Article
• Pam16 has an essential role in the mitochondrial protein import motor  Academic Article
• Pentameric CRP attenuates inflammatory effects of mmLDL by inhibiting mmLDL–monocyte interactions  Academic Article
• Peptide mimics selected from immune sera using phage display technology can replace native antigens in the diagnosis of Epstein-Barr virus infection  Academic Article
• Persistent organic pollutants and diabetes: A review of the epidemiological evidence  Academic Article
• Phage display for epitope determination: A paradigm for identifying receptor–ligand interactions  Academic Article
• Phenylalanine residues act as membrane anchors in the antimicrobial action of Aurein 1.2  Academic Article
• Phosphoinositide-mediated oligomerization of a defensin induces cell lysis  Academic Article
• Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators  Academic Article
• Physical characterization of serpin conformations  Academic Article
• Physiological restraint of Bak by Bcl-x(L) is essential for cell survival  Academic Article
• Plant-specific preprotein and amino acid transporter proteins are required for tRNA import into mitochondria  Academic Article
• Plasminogen Is Tethered with High Affinity to the Cell Surface by the Plasma Protein, Histidine-rich Glycoprotein  Academic Article
• Platelet Function During and After Thrombolytic Therapy for Acute Myocardial Infarction With Reteplase, Alteplase, or Streptokinase  Academic Article
• PoPS: a computational tool for modeling and predicting protease specificity  Conference Paper
• PoPS: a computational tool for modeling and predicting protease specificity.  Academic Article
• Polyglutamine aggregation in Huntington and related diseases  Chapter
• Polymorphisms in Erythrocyte Binding Antigens 140 and 181 Affect Function and Binding but Not Receptor Specificity in Plasmodium falciparum  Academic Article
• Postchemotherapy and Tumor-Selective Targeting with the La-Specific DAB4 Monoclonal Antibody Relates to Apoptotic Cell Clearance  Academic Article
• Predicting distinct organization of transcription factor binding sites on the promoter regions: a new genome-based approach to expand human embryonic stem cell regulatory network  Academic Article
• Predicting serpin/protease interactions  Academic Article
• ProBAPred: Inferring protein-protein binding affinity by incorporating protein sequence and structural features  Academic Article
• Protective hinge in insulin opens to enable its receptor engagement  Academic Article
• Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis  Academic Article
• Proteinase-activated receptor-2 (PAR2) and mouse osteoblasts: Regulation of cell function and lack of specificity of PAR2-activating peptides  Academic Article
• Proteogenomic Analysis Identifies a Novel Human SHANK3 Isoform  Academic Article
• Proteolytically active complexes of cathepsin L and a cysteine proteinase inhibitor; purification and demonstration of their formation in vitro  Academic Article
• Proteomic comparison of 3D and 2D glioma models reveals increased HLA-E expression in 3D models is associated with resistance to NK cell-mediated cytotoxicity  Academic Article
• Proteomic identification of galectin-11 and -14 ligands from Fasciola hepatica  Academic Article
• Pseudohypoaldosteronism type 1: the index case revisited  Academic Article
• Psychotropic drug-induced locomotor hyperactivity and prepulse inhibition regulation in male and female aromatase knockout (ArKO) mice: role of dopamine D1 and D2 receptors and dopamine transporters  Academic Article
• Purification of a ligand for the EPH-like receptor HEK using a biosensor-based affinity detection approach.  Academic Article
• Purified rat peritoneal mast cells: Characteristics of the removal and binding of IgE  Academic Article
• Putative bovine topological association domains and CTCF binding motifs can reduce the search space for causative regulatory variants of complex traits  Academic Article
• Quantitative Analysis of the Microtubule Interaction of Rabies Virus P3 Protein: Roles in Immune Evasion and Pathogenesis  Academic Article
• Quantum polarized ligand docking investigation to understand the significance of protonation states in histone deacetylase inhibitors  Academic Article
• Quinazoline Sulfonamides as Dual Binders of the Proteins B-Cell Lymphoma 2 and B-Cell Lymphoma Extra Long with Potent Proapoptotic Cell-Based Activity  Academic Article
• Raf Kinase Inhibitor Protein Interacts with NF-κB-Inducing Kinase and TAK1 and Inhibits NF-κB Activation  Academic Article
• Rapid and precise epitope mapping of monoclonal antibodies against Plasmodium falciparum AMA1 by combined phage display of fragments and random peptides  Academic Article
• Ras enhances TGF-β signaling by decreasing cellular protein levels of its type II receptor negative regulator SPSB1  Academic Article
• Recognition by host nuclear transport proteins drives disorder-to-order transition in Hendra virus V  Academic Article
• Recognition of β-linked self glycolipids mediated by natural killer T cell antigen receptors  Academic Article
• Reduced abundance of the E3 ubiquitin ligase E6AP contributes to decreased expression of the INK4/ARF locus in non–small cell lung cancer  Academic Article
• Reduced striatal D1 receptor binding in autosomal dominant nocturnal frontal lobe epilepsy  Academic Article
• Regulation of cellular and PCP signalling by the Scribble polarity module  Academic Article
• Regulation of histidine-rich glycoprotein (HRG) function via plasmin-mediated proteolytic cleavage  Academic Article
• Relaxin-like bioactivity of ovine Insulin 3 (INSL3) analogues  Academic Article
• Residue-Based Preorganization of BH3-Derived α/β-Peptides: Modulating Affinity, Selectivity and Proteolytic Susceptibility in α-Helix Mimics  Academic Article
• Residues Surrounding the Glycosylphosphatidylinositol Anchor Attachment Site of PrP Modulate Prion Infection: Insight from the Resistance of Rabbits to Prion Disease  Academic Article
• Resistance to heat radiosensitization and protein damage in thermotolerant and thermoresistant cells  Academic Article
• Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation  Academic Article
• S-nitrosylation and S-glutathionylation of Cys134 on troponin I have opposing competitive actions on Ca²⁺ sensitivity in rat fast-twitch muscle fibers  Academic Article
• S100P-Derived RAGE Antagonistic Peptide Reduces Tumor Growth and Metastasis  Academic Article
• SOMEA: self-organizing map based extraction algorithm for DNA motif identification with heterogeneous model  Academic Article
• Scabies Mite Inactivated Serine Protease Paralogs Inhibit the Human Complement System  Academic Article
• Scribble Interacts with β-Catenin to Localize Synaptic Vesicles to Synapses  Academic Article
• Sec15 Is an Effector for the Rab11 GTPase in Mammalian Cells  Academic Article
• Selective coupling of type 6 adenylyl cyclase with type 2 IP3 receptors mediates direct sensitization of IP3 receptors by cAMP  Academic Article
• Selective inhibition of Biotin Protein Ligase from Staphylococcus aureus  Academic Article
• Selective toxicity of MKT-077 to cancer cells is mediated by its binding to the hsp70 family protein mot-2 and reactivation of p53 function  Academic Article
• Self-Assembled Enzyme Nanoparticles for Carbon Dioxide Capture  Academic Article
• Self-Assembly of Peptides into Spherical Nanoparticles for Delivery of Hydrophilic Moieties to the Cytosol  Academic Article
• Semantic and layered protein function prediction from PPI networks  Academic Article
• Semantically predicting protein functions based on protein functional connectivity  Academic Article
• Sent packing: Protein engineering generates a new crystal form of Pseudomonas aeruginosa DsbA1 with increased catalytic surface accessibility  Academic Article
• Serpins: Finely Balanced Conformational Traps  Academic Article
• Shark IgNAR antibody mimotopes target a murine immunoglobulin through extended CDR3 loop structures  Academic Article
• Smac Mimetics Activate the E3 Ligase Activity of cIAP1 Protein by Promoting RING Domain Dimerization  Academic Article
• Solution Structure of Ectodomains of the Insulin Receptor Family: The Ectodomain of the Type 1 Insulin-Like Growth Factor Receptor Displays Asymmetry of Ligand Binding Accompanied by Limited Conformational Change  Academic Article
• Solution structure of an ultra-stable single-chain insulin analog connects protein dynamics to a novel mechanism of receptor binding  Academic Article
• SoybeanSAT1(Symbiotic Ammonium Transporter 1) encodes a bHLH transcription factor involved in nodule growth and NH4+ transport  Academic Article
• Structural Basis for Apoptosis Inhibition by Epstein-Barr Virus BHRF1  Academic Article
• Structural Basis for Broad Substrate Specificity in Higher Plant β-d-Glucan Glucohydrolases  Academic Article
• Structural Basis for Tetrodotoxin-resistant Sodium Channel Binding by μ-Conotoxin SmIIIA  Academic Article
• Structural Basis for the Recognition and Cross-linking of Amyloid Fibrils by Human Apolipoprotein E  Academic Article
• Structural Basis of Binding by Cyclic Nonphosphorylated Peptide Antagonists of Grb7 Implicated in Breast Cancer Progression  Academic Article
• Structural Determinants Defining the Allosteric Inhibition of an Essential Antibiotic Target  Academic Article
• Structural Insight into BH3 Domain Binding of Vaccinia Virus Antiapoptotic F1L  Academic Article
• Structural Rationale for Low-Nanomolar Binding of Transition State Mimics to a Family GH3 β-d-Glucan Glucohydrolase from Barley†,‡  Academic Article
• Structural Roles for Human Translation Factor eIF3 in Initiation of Protein Synthesis  Academic Article
• Structural Studies of the Resistance of Influenza Virus Neuramindase to Inhibitors  Academic Article
• Structural analysis of phosphorylation-associated interactions of human MCC with Scribble PDZ domains  Academic Article
• Structural and Biological Characterization of Murine-Human Interleukin-6 Chimeras  Conference Paper
• Structural and functional characterization of the mitochondrial complex IV assembly factor Coa6  Academic Article
• Structural and functional insight into canarypox virus CNP058 mediated regulation of apoptosis  Academic Article
• Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses  Academic Article
• Structural basis for plasmep sin V inhibition that blocks export of malaria proteins to human erythrocytes  Academic Article
• Structural basis for substrate specificity of Helicobacter pylori M17 aminopeptidase  Academic Article
• Structural basis for the high-affinity interaction of nidogen-1 with immunoglobulin-like domain 3 of perlecan  Academic Article
• Structural basis of Deerpox virus-mediated inhibition of apoptosis  Academic Article
• Structural basis of N‐end rule substrate recognition in Escherichia coli by the ClpAP adaptor protein ClpS  Academic Article
• Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1.  Academic Article
• Structural basis of interprotein electron transfer in bacterial sulfite oxidation  Academic Article
• Structural characterisation of the fatty acid biosynthesis enzyme FabF from the pathogen Listeria monocytogenes  Academic Article
• Structural insight into African swine fever virus A179L-mediated inhibition of apoptosis  Academic Article
• Structural insight into an evolutionarily ancient programmed cell death regulator – the crystal structure of marine sponge BHP2 bound to LB-Bak-2  Academic Article
• Structural insights into BCL2 pro-survival protein interactions with the key autophagy regulator BECN1 following phosphorylation by STK4/MST1  Academic Article
• Structure and Function of the Oxidoreductase DsbA1 from Neisseria meningitidis  Academic Article
• Structure and characterisation of a key epitope in the conserved C-terminal domain of the malaria vaccine candidate MSP2  Academic Article
• Structure of Aldehyde Reductase Holoenzyme in Complex with the Potent Aldose Reductase Inhibitor Fidarestat:  Implications for Inhibitor Binding and Selectivity  Academic Article
• Structure of a calcium-deficient form of influenza virus neuraminidase: implications for substrate binding  Academic Article
• Structure of human aldose reductase holoenzyme in complex with Statil: An approach to structure-based inhibitor design of the enzyme  Academic Article
• Structure of the BH3 Domains from the p53-Inducible BH3-Only Proteins Noxa and Puma in Complex with Mcl-1  Academic Article
• Structure of the defensin NsD7 in complex with PIP 2 reveals that defensin : lipid oligomer topologies are dependent on lipid type  Academic Article
• Structure of the tetrameric form of human L-Xylulose reductase: Probing the inhibitor-binding site with molecular modeling and site-directed mutagenesis  Academic Article
• Structure ofEscherichia coliaminopeptidase P in complex with the inhibitor apstatin  Academic Article
• Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction  Academic Article
• Structure-Function analysis of human IL-6: Identification of two distinct regions that are important for receptor binding  Academic Article
• Structure-guided design of a selective BCL-XL inhibitor  Academic Article
• Structures of the cIAP2 RING Domain Reveal Conformational Changes Associated with Ubiquitin-conjugating Enzyme (E2) Recruitment  Academic Article
• Studies on 3-Deoxy-d-arabinoheptulosonate-7-phosphate Synthetase(phe) from Escherichia coli K12. 3. Structural Studies  Academic Article
• SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase  Academic Article
• Subcomplexes of ancestral respiratory complex i subunits rapidly turn over in vivo as productive assembly intermediates in arabidopsis  Academic Article
• Substituted Pyridazin-3(2H)-ones as Highly Potent and Biased Formyl Peptide Receptor Agonists  Academic Article
• Substrate recognition and processing by a Walker B mutant of the human mitochondrial AAA+ protein CLPX  Academic Article
• Symplekin, a polyadenylation factor, prevents MOZ and MLL activity on HOXA9 in hematopoietic cells  Academic Article
• Syntaxin 7 Complexes with Mouse Vps10p Tail Interactor 1b, Syntaxin 6, Vesicle-associated Membrane Protein (VAMP)8, and VAMP7 in B16 Melanoma Cells  Academic Article
• Synthesis and biological evaluation of 2-anilino-4-substituted-7H-pyrrolopyrimidines as PDK1 inhibitors  Academic Article
• T cells recognizing a 11mer influenza peptide complexed to H-2D(b) show promiscuity for peptide length  Academic Article
• TDP-43 stabilises the processing intermediates of mitochondrial transcripts  Academic Article
• TRAF2 Must Bind to Cellular Inhibitors of Apoptosis for Tumor Necrosis Factor (TNF) to Efficiently Activate NF-κB and to Prevent TNF-induced Apoptosis  Academic Article
• TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα  Academic Article
• Tandem LIM domains provide synergistic binding in the LMO4:Ldb1 complex  Academic Article
• Targeted Delivery of an ssrA-Tagged Substrate by the Adaptor Protein SspB to Its Cognate AAA+ Protein ClpX  Academic Article
• Targeting Ligand-Induced Binding Sites on GPIIb/IIIa via Single-Chain Antibody Allows Effective Anticoagulation Without Bleeding Time Prolongation  Academic Article
• Targeting cancer cells: Controlling the binding and internalization of antibody-functionalized capsules  Academic Article
• Targeting neuropilin-1 in human leukemia and lymphoma  Academic Article
• Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53  Academic Article
• Targeting the Role of a Key Conserved Motif for Substrate Selection and Catalysis by 3-Deoxy-d-manno-octulosonate 8-Phosphate Synthase  Academic Article
• The Assembly Pathway of the Mitochondrial Carrier Translocase Involves Four Preprotein Translocases  Academic Article
• The Assessment and Characterisation of Drug Plasma Protein Binding in the Body Using QSAR  Academic Article
• The Brm-HDAC3-Erm repressor complex suppresses dedifferentiation in Drosophila type II neuroblast lineages  Academic Article
• The Dictyostelium genome encodes numerous RasGEFs with multiple biological roles.  Academic Article
• The EGFRvIII variant in glioblastoma multiforme  Academic Article
• The Elusive Role of the Potential Factor X Cation-binding Exosite-1 in Substrate and Inhibitor Interactions  Academic Article
• The GP IIb/IIIa inhibitor abciximab (c7E3) inhibits the binding of various ligands to the leukocyte integrin Mac-1 (CD11b/CD18, αMβ2)  Academic Article
• The High Resolution Crystal Structure of the Human Tumor Suppressor Maspin Reveals a Novel Conformational Switch in the G-helix  Academic Article
• The Initiation of GTP Hydrolysis by the G-Domain of FeoB: Insights from a Transition-State Complex Structure  Academic Article
• The Interaction of Bioactive Peptides with an Immobilized Phosphatidylcholine Monolayer  Academic Article
• The Interleukin-6 (IL-6) Partial Antagonist (Q159E,T162P)IL-6 Interacts with the IL-6 Receptor and gp130 but Fails to Induce a Stable Hexameric Receptor Complex  Academic Article
• The Intestinal Epithelial Cell Differentiation Marker Intestinal Alkaline Phosphatase (ALPi) Is Selectively Induced by Histone Deacetylase Inhibitors (HDACi) in Colon Cancer Cells in a Kruppel-like Factor 5 (KLF5)-dependent Manner  Academic Article
• The LRRK2-related Roco kinase Roco2 is regulated by Rab1A and controls the actin cytoskeleton  Academic Article
• The Membrane-Bound NAC Transcription Factor ANAC013 Functions in Mitochondrial Retrograde Regulation of the Oxidative Stress Response in Arabidopsis  Academic Article
• The Merozoite Surface Protein 1 Complex Is a Platform for Binding to Human Erythrocytes by Plasmodium falciparum  Academic Article
• The Multidrug Resistance Protein Is Photoaffinity Labeled by a Quinoline-Based Drug at Multiple Sites†  Academic Article
• The Mycoplasma hyorhinis p37 Protein Rapidly Induces Genes in Fibroblasts Associated with Inflammation and Cancer  Academic Article
• The N-Terminus of gp130 is Critical for the Formation of the High-Affinity Interleukin-6 Receptor Complex  Academic Article
• The N-end rule pathway: From recognition by N-recognins, to destruction by AAA+proteases  Academic Article
• The N-terminal segment of antithrombin acts as a steric gate for the binding of heparin  Academic Article
• The Proapoptotic Activity of the Bcl-2 Family Member Bim Is Regulated by Interaction with the Dynein Motor Complex  Academic Article
• The RNA-binding Protein MEX3B Mediates Resistance to Cancer Immunotherapy by Downregulating HLA-A Expression  Academic Article
• The Retinoblastoma Protein Selectively Represses E2F1 Targets via a TAAC DNA Element during Cellular Senescence  Academic Article
• The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4–binding residues  Academic Article
• The Scs disulfide reductase system cooperates with the metallochaperone CueP in Salmonella copper resistance  Academic Article
• The Single-Ring Thermoanaerobacter brockii Chaperonin 60 (Tbr-EL7) Dimerizes to Tbr-EL14.cntdot.Tbr-ES7 under Protein Folding Conditions  Academic Article
• The Structural Biology of Bcl-xL  Academic Article
• The Structure of SOCS3 Reveals the Basis of the Extended SH2 Domain Function and Identifies an Unstructured Insertion That Regulates Stability  Academic Article
• The Trypanosomal Trans-Sialidase  Academic Article
• The X-ray Crystal Structure of Full-Length Human Plasminogen  Academic Article
• The X-ray Structure of a Hemipteran Ecdysone Receptor Ligand-binding Domain  Academic Article
• The alpha 2-adrenergic receptor: multiple affinity states and regulation of a receptor inversely coupled to adenylate cyclase.  Academic Article
• The amino-terminal sequence of the 85–90K nonhormone binding component of the molybdate-stabilized estradiol receptor from calf uterus  Academic Article
• The antigen 43 structure reveals a molecular Velcro-like mechanism of autotransporter-mediated bacterial clumping  Academic Article
• The antimalarial drug, chloroquine, interacts with lactate dehydrogenase from Plasmodium falciparum  Academic Article
• The assembly pathway of the mitochondrial carrier translocase involves four preprotein translocases  Academic Article
• The basal proton conductance of mitochondria depends on adenine nucleotide translocase content  Academic Article
• The crystal structure of the CopC protein from Pseudomonas fluorescens reveals amended classifications for the CopC protein family  Academic Article
• The cysteine synthase complex from plants  Academic Article
• The effect of buffered aspirin on plasma indomethacin  Academic Article
• The effect of physiologically occurring cations upon aequorin light emission. Determination of the binding constants  Academic Article
• The effects of exosite occupancy on the substrate specificity of thrombin  Academic Article
• The functional differences between pro-survival and pro-apoptotic B cell lymphoma 2 (Bcl-2) proteins depend on structural differences in their Bcl-2 homology 3 (BH3) domains  Academic Article
• The immune receptor NOD1 and kinase RIP2 interact with bacterial peptidoglycan on early endosomes to promote autophagy and inflammatory signaling  Academic Article
• The interactome of LIM domain proteins: The contributions of LIM domain proteins to heart failure and heart development  Academic Article
• The mature-parasite-infected erythrocyte surface antigen (MESA) of Plasmodium falciparum associates with the erythrocyte membrane skeletal protein, band 4.1  Academic Article
• The molecular switches controlling the interaction between complement proteases of the classical and lectin pathways and their substrates  Academic Article
• The plant defensin NaD1 introduces membrane disorder through a specific interaction with the lipid, phosphatidylinositol 4,5 bisphosphate  Academic Article
• The prion protein gene: Identifying regulatory signals using marsupial sequence  Academic Article
• The protein encoded by the MFT1 gene is a targeting factor for mitochondrial precursor proteins, and not a core ribosomal protein  Academic Article
• The purification of the σFpvI/FpvR20 and σPvdS/FpvR20 protein complexes is facilitated at room temperature  Academic Article
• The restricted binding repertoire of Bcl-B leaves Bim as the universal BH3-only prosurvival Bcl-2 protein antagonist  Academic Article
• The role of proteases in regulating Eph/ephrin signaling  Academic Article
• The role of strand 1 of the C β-sheet in the structure and function of α1-antitrypsin  Academic Article
• The self-association of l-α-hydroxyacid oxidase  Academic Article
• The structural influence of individual residues located within peptide antigen depends upon their sequence context  Academic Article
• The structure and activity of the glutathione reductase from Streptococcus pneumoniae  Academic Article
• The trans-Golgi network GRIP-domain proteins form α-helical homodimers  Academic Article
• The transcription factor MYB29 Is a regulator of ALTERNATIVE OXIDASE1a  Academic Article
• The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells  Academic Article
• The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation  Academic Article
• Therapeutic integrin inhibition: Allosteric and activation-specific inhibition strategies may surpass the initial ligand-mimetic strategies  Academic Article
• Thermostability and reversibility of silver nanoparticle–protein binding  Academic Article
• Transition-State Analogue γ-Secretase Inhibitors Stabilize a 900 kDa Presenilin/Nicastrin Complex†  Academic Article
• Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites  Academic Article
• Translocation of Proteins into Mitochondria  Academic Article
• Treatment of ras-induced cancers by the F-actin-bundling drug MKT-077  Academic Article
• Triggering of Apoptosis by Puma Is Determined by the Threshold Set by Prosurvival Bcl-2 Family Proteins  Academic Article
• Trim33 Binds and Silences a Class of Young Endogenous Retroviruses in the Mouse Testis; a Novel Component of the Arms Race between Retrotransposons and the Host Genome  Academic Article
• Tumor Necrosis Factor (TNF) Signaling, but Not TWEAK (TNF-like Weak Inducer of Apoptosis)-triggered cIAP1 (Cellular Inhibitor of Apoptosis Protein 1) Degradation, Requires cIAP1 RING Dimerization and E2 Binding  Academic Article
• Tumor Suppressor Scribble Regulates Assembly of Tight Junctions in the Intestinal Epithelium  Academic Article
• Tumor-Specific Hsp70 Plasma Membrane Localization Is Enabled by the Glycosphingolipid Gb3  Academic Article
• Two-dimensional electrophoretic analysis of mixed lineage kinase 2N-terminal domain binding proteins  Conference Paper
• Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7  Academic Article
• Unraveling the Redox Properties of the Global Regulator FurA from Anabaena sp PCC 7120: Disulfide Reductase Activity Based on Its CXXC Motifs  Academic Article
• Unzipping the role of chirality in nanoscale self-assembly of tripeptide hydrogels  Academic Article
• Uptake of a cell permeable G7-18NATE construct into cells and binding with the Grb7-SH2 domain  Conference Paper
• Use of Engineered Unique Cysteine Residues to Facilitate Oriented Coupling of Proteins Directly to a Gold Substrate  Academic Article
• Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands  Academic Article
• Vimentin Regulates Scribble Activity by Protecting It from Proteasomal Degradation  Academic Article
• What Lies Beneath: Antibody Dependent Natural Killer Cell Activation by Antibodies to Internal Influenza Virus Proteins  Academic Article
• When phosphorylated at Thr(148), the beta(2)-subunit of AMP-activated kinase does not associate with glycogen in skeletal muscle  Academic Article
• Whole exome sequencing identifies a recurrent RQCD1 P131L mutation in cutaneous melanoma  Academic Article
• Wiz binds active promoters and CTCF-binding sites and is required for normal behaviour in the mouse  Academic Article
• Workshop Summary: Novel Aspects of the Functions of the TRAFs and cIAPs  Conference Paper
• X-ray structure of a carpet-like antimicrobial defensin-phospholipid membrane disruption complex  Academic Article
• alpha/beta-Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity in Living Cells  Academic Article
• i-bodies, Human Single Domain Antibodies That Antagonize Chemokine Receptor CXCR4  Academic Article
• β‐adrenergic stimulation induces histone deacetylase 5 (HDAC5) nuclear accumulation in cardiomyocytes by B55α‐PP2A‐mediated dephosphorylation  Academic Article
• ‘MCC’ protein interacts with E-cadherin and β-catenin strengthening cell–cell adhesion of HCT116 colon cancer cells  Academic Article