Protein Kinases
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A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs Academic Article
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A cyclin B homolog in S. cerevisiae: Chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis Academic Article
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A family of cyclin homologs that control the G1 phase in yeast. Academic Article
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A putative kinase-related protein (PKRP) from Plasmodium berghei mediates infection in the midgut and salivary glands of the mosquito Academic Article
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Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death Academic Article
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Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner Academic Article
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Analysis of the Cdc28 protein kinase complex by dosage suppression Academic Article
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Attenuation of cardiac hypertrophy by inhibiting both mTOR and NFκB activation in vivo Academic Article
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Bioinformatics in protein kinases regulatory network and drug discovery Academic Article
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C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1 Academic Article
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Ca2+activation of diffusible and bound pools of μ-calpain in rat skeletal muscle Academic Article
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Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways Academic Article
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Complete Nucleotide Sequence, Expression, and Chromosomal Localisation of Human Mixed-Lineage Kinase 2 Academic Article
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Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis Academic Article
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Disruption of excitation-contraction coupling and titin by endogenous Ca2+-activated proteases in toad muscle fibres Academic Article
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Distinct modes of cyclin E/cdc2c kinase regulation and S-phase control in mitotic and endoreduplication cycles of Drosophila embryogenesis. Academic Article
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Dominant negative protein kinase mutations that confer a G1 arrest phenotype. Academic Article
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Dual TNFα-Induced Effects on NRF2 Mediated Antioxidant Defence in Astrocyte-Rich Cultures: Role of Protein Kinase Activation Academic Article
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Dysregulation of hepatocyte cell cycle and cell viability by hepatitis B virus Academic Article
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Effect of carbohydrate ingestion on exercise-induced alterations in metabolic gene expression Academic Article
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Evolutionary divergence of the necroptosis effector MLKL Academic Article
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Exposure to rosiglitazone, a PPAR-gamma agonist, in late gestation reduces the abundance of factors regulating cardiac metabolism and cardiomyocyte size in the sheep fetus Academic Article
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Extracellular ATP, ecto-ATPase and calcium influx in Dictyostelium discoideum
cells Academic Article
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Fight or flight: Regulation of emergency hematopoiesis by pyroptosis and necroptosis Academic Article
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Flavonols and Flavones – Protecting Against Myocardial Ischemia/ Reperfusion Injury by Targeting Protein Kinases Academic Article
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HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death Academic Article
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Heparin-activated protein kinase from rabbit muscle: Relationship to enzymes of the glycogen synthase kinase-3 category Academic Article
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Hormone-sensitive lipase from swine adipose tissue: Identification and some properties Academic Article
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Human cDNAs encoding homologs of the small p34Cdc28/Cdc2-associated protein of Saccharomyces cerevisiae and Schizosaccharomyces pombe. Academic Article
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Induction of inclusion formation and disruption of lamin A/C structure by premutation CGG-repeat RNA in human cultured neural cells Academic Article
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Inhibition of mTOR Signaling With Rapamycin Regresses Established Cardiac Hypertrophy Induced by Pressure Overload Academic Article
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Inhibition of the MAP kinase cascade blocks heregulin-induced cell cycle progression in T-47D human breast cancer cells Academic Article
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Inhibition of wheat embryo calcium-dependent protein kinase by acridines and azaacridines Academic Article
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Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL Academic Article
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Intact Mitochondrial Electron Transport Function is Essential for Signalling by Hydrogen Peroxide in Cardiac Myocytes Academic Article
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LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis Academic Article
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Lgl, aPKC, and Crumbs Regulate the Salvador/Warts/Hippo Pathway through Two Distinct Mechanisms Academic Article
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Lgl, the SWH pathway and tumorigenesis: It’s a matter of context and competition! Academic Article
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Lgl/aPKC and Crb regulate the Salvador/Warts/Hippo pathway Academic Article
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M2, a novel anthracenedione, elicits a potent DNA damage response that can be subverted through checkpoint kinase inhibition to generate mitotic catastrophe Academic Article
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Methods for studying TNF-mediated necroptosis in cultured cells Chapter
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MidA is a putative methyltransferase that is required for mitochondrial complex I function Academic Article
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Mining Protein Kinases Regulation Using Graphical Models Academic Article
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Molecular Basis of Fc Receptor Function Academic Article
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Multiple phosphorylation of mouse muscle glycogen synthase Academic Article
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Multiple phosphorylation sites of rat liver glycogen synthase Academic Article
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Necroptosis induced by RIPK3 requires MLKL but not Drp1 Academic Article
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Necroptosis signalling is tuned by phosphorylation of MLKL residues outside the pseudokinase domain activation loop Academic Article
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PI3K(p110α) Inhibitors as Anti-Cancer Agents: Minding the Heart Academic Article
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Phosphorylation of glycogen synthase by the Ca2+- and phospholipid-activated protein kinase (protein kinase C) Academic Article
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Phosphorylation of human growth hormone by the epidermal growth factor-stimulated tyrosine kinase. Academic Article
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Protein kinase C and downstream signaling pathways in a three-dimensional model of phorbol ester-induced angiogenesis Academic Article
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RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis Academic Article
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RIPK1-and RIPK3-induced cell death mode is determined by target availability Academic Article
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RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL Academic Article
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Rapamycin Attenuates Load-Induced Cardiac Hypertrophy in Mice Academic Article
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Redox Control of Endothelial Function and Dysfunction: Molecular Mechanisms and Therapeutic Opportunities Academic Article
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Regulation of Starch Stores by a Ca2+-Dependent Protein Kinase Is Essential for Viable Cyst Development in Toxoplasma gondii Academic Article
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Signaling Mechanisms Underlying Slit2-Induced Collapse of Xenopus Retinal Growth Cones Academic Article
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The LRRK2-related Roco kinase Roco2 is regulated by Rab1A and controls the actin cytoskeleton Academic Article
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The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis Academic Article
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The Salvador/Warts/Hippo pathway controls regenerative tissue growth in Drosophila melanogaster Academic Article
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The UBA domain of SnRK1 promotes activation and maintains catalytic activity Academic Article
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The brace helices of MLKL mediate interdomain communication and oligomerisation to regulate cell death by necroptosis Academic Article
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The brassinosteroid receptor BRI1 can generate cGMP enabling cGMP-dependent downstream signaling Academic Article
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The diverse role of RIP kinases in necroptosis and inflammation Academic Article
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The importance of being chaperoned: HSP90 and necroptosis Editorial Article
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The intersection of cell death and inflammasome activation Academic Article
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The mouse Plk gene: structural characterization, chromosomal localization and identification of a processed Plk pseudogene Academic Article
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The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism Academic Article
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The tyrosine kinase McsB is a regulated adaptor protein for ClpCP Academic Article
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Transcriptional Output of the Salvador/Warts/Hippo Pathway Is Controlled in Distinct Fashions in Drosophila melanogaster and Mammalian Cell Lines Academic Article
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gp130-mediated Signal Transduction in Embryonic Stem Cells Involves Activation of Jak and Ras/Mitogen-activated Protein Kinase Pathways Academic Article