subject area of

• A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs  Academic Article
• A cyclin B homolog in S. cerevisiae: Chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis  Academic Article
• A family of cyclin homologs that control the G1 phase in yeast.  Academic Article
• A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction  Academic Article
• A putative kinase-related protein (PKRP) from Plasmodium berghei mediates infection in the midgut and salivary glands of the mosquito  Academic Article
• Activated MLKL attenuates autophagy following its translocation to intracellular membranes  Academic Article
• Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death  Academic Article
• Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner  Academic Article
• Analysis of the Cdc28 protein kinase complex by dosage suppression  Academic Article
• Bioinformatics in protein kinases regulatory network and drug discovery  Academic Article
• C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1  Academic Article
• Ca2+activation of diffusible and bound pools of μ-calpain in rat skeletal muscle  Academic Article
• Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways  Academic Article
• Complete Nucleotide Sequence, Expression, and Chromosomal Localisation of Human Mixed-Lineage Kinase 2  Academic Article
• Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis  Academic Article
• Cytosolic PTEN-induced putative kinase 1 is stabilized by the NF-κB pathway and promotes non-selective mitophagy  Academic Article
• Disruption of excitation-contraction coupling and titin by endogenous Ca2+-activated proteases in toad muscle fibres  Academic Article
• Distinct modes of cyclin E/cdc2c kinase regulation and S-phase control in mitotic and endoreduplication cycles of Drosophila embryogenesis.  Academic Article
• Dominant negative protein kinase mutations that confer a G1 arrest phenotype.  Academic Article
• Dysregulation of hepatocyte cell cycle and cell viability by hepatitis B virus  Academic Article
• Effect of carbohydrate ingestion on exercise-induced alterations in metabolic gene expression  Academic Article
• Evolutionary divergence of the necroptosis effector MLKL  Academic Article
• Exposure to rosiglitazone, a PPAR-gamma agonist, in late gestation reduces the abundance of factors regulating cardiac metabolism and cardiomyocyte size in the sheep fetus  Academic Article
• Extracellular ATP, ecto-ATPase and calcium influx inDictyostelium discoideumcells  Academic Article
• Fight or flight: Regulation of emergency hematopoiesis by pyroptosis and necroptosis  Academic Article
• Flavonols and Flavones – Protecting Against Myocardial Ischemia/ Reperfusion Injury by Targeting Protein Kinases  Academic Article
• HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death  Academic Article
• Human cDNAs encoding homologs of the small p34Cdc28/Cdc2-associated protein of Saccharomyces cerevisiae and Schizosaccharomyces pombe.  Academic Article
• Identifying interactions between kinases and substrates based on protein-protein interaction network  Academic Article
• Inhibition of AKT signalling by benzoxazine derivative LTUR6 through the modulation of downstream kinases  Academic Article
• Inhibition of the MAP kinase cascade blocks heregulin-induced cell cycle progression in T-47D human breast cancer cells  Academic Article
• Inhibition of wheat embryo calcium-dependent protein kinase by acridines and azaacridines  Academic Article
• Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL  Academic Article
• Intact Mitochondrial Electron Transport Function is Essential for Signalling by Hydrogen Peroxide in Cardiac Myocytes  Academic Article
• LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis  Academic Article
• Lgl, aPKC, and Crumbs Regulate the Salvador/Warts/Hippo Pathway through Two Distinct Mechanisms  Academic Article
• Lgl, the SWH pathway and tumorigenesis: It’s a matter of context and competition!  Academic Article
• Lgl/aPKC and Crb regulate the Salvador/Warts/Hippo pathway  Academic Article
• M2, a novel anthracenedione, elicits a potent DNA damage response that can be subverted through checkpoint kinase inhibition to generate mitotic catastrophe  Academic Article
• MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis  Academic Article
• Methods for studying TNF-mediated necroptosis in cultured cells  Chapter
• MidA is a putative methyltransferase that is required for mitochondrial complex I function  Academic Article
• Mining Protein Kinases Regulation Using Graphical Models  Academic Article
• Molecular Basis of Fc Receptor Function  Academic Article
• Necroptosis induced by RIPK3 requires MLKL but not Drp1  Academic Article
• Necroptosis signalling is tuned by phosphorylation of MLKL residues outside the pseudokinase domain activation loop  Academic Article
• Phosphorylation of human growth hormone by the epidermal growth factor-stimulated tyrosine kinase.  Academic Article
• Protein kinase C and downstream signaling pathways in a three-dimensional model of phorbol ester-induced angiogenesis  Academic Article
• RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis  Academic Article
• RIPK1-and RIPK3-induced cell death mode is determined by target availability  Academic Article
• RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL  Academic Article
• Redox Control of Endothelial Function and Dysfunction: Molecular Mechanisms and Therapeutic Opportunities  Academic Article
• Regulation of Starch Stores by a Ca2+-Dependent Protein Kinase Is Essential for Viable Cyst Development in Toxoplasma gondii  Academic Article
• Signaling Mechanisms Underlying Slit2-Induced Collapse of Xenopus Retinal Growth Cones  Academic Article
• The LRRK2-related Roco kinase Roco2 is regulated by Rab1A and controls the actin cytoskeleton  Academic Article
• The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis  Academic Article
• The Salvador/Warts/Hippo pathway controls regenerative tissue growth in Drosophila melanogaster  Academic Article
• The UBA domain of SnRK1 promotes activation and maintains catalytic activity  Academic Article
• The brace helices of MLKL mediate interdomain communication and oligomerisation to regulate cell death by necroptosis  Academic Article
• The brassinosteroid receptor BRI1 can generate cGMP enabling cGMP-dependent downstream signaling  Academic Article
• The diverse role of RIP kinases in necroptosis and inflammation  Academic Article
• The importance of being chaperoned: HSP90 and necroptosis  Editorial Article
• The intersection of cell death and inflammasome activation  Academic Article
• The mouse Plk gene: structural characterization, chromosomal localization and identification of a processed Plk pseudogene  Academic Article
• The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism  Academic Article
• The tyrosine kinase McsB is a regulated adaptor protein for ClpCP  Academic Article
• Transcriptional Output of the Salvador/Warts/Hippo Pathway Is Controlled in Distinct Fashions in Drosophila melanogaster and Mammalian Cell Lines  Academic Article
• gp130-mediated Signal Transduction in Embryonic Stem Cells Involves Activation of Jak and Ras/Mitogen-activated Protein Kinase Pathways  Academic Article