Protein Structure, Secondary
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(α/β+α)-Peptide Antagonists of BH3 Domain/Bcl-xLRecognition: Toward General Strategies for Foldamer-Based Inhibition of Protein−Protein Interactions Academic Article
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A Common Fold Mediates Vertebrate Defense and Bacterial Attack Academic Article
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A Molecular Switch Governs the Interaction between the Human Complement Protease C1s and Its Substrate, Complement C4 Academic Article
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A SAM oligomerization domain shapes the genomic binding landscape of the LEAFY transcription factor Academic Article
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A Structural Investigation of NRZ Mediated Apoptosis Regulation in Zebrafish Academic Article
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A Structural Model for Apolipoprotein C-II Amyloid Fibrils: Experimental Characterization and Molecular Dynamics Simulations Academic Article
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A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR Academic Article
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A mortise-tenon joint in the transmembrane domain modulates autotransporter assembly into bacterial outer membranes. Academic Article
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A novel two-chain proteinase inhibitor generated by circularization of a multidomain precursor protein Academic Article
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A partially structured region of a largely unstructured protein,Plasmodium falciparummerozoite surface protein 2 (MSP2), forms amyloid-like fibrils Academic Article
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A radish seed antifungal peptide with a high amyloid fibril-forming propensity Academic Article
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A structural characterization of the isoniazid Mycobacterium tuberculosis drug target, Rv2971, in its unliganded form. Academic Article
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A suite of Switch i and Switch II mutant structures from the G-protein domain of FeoB Academic Article
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Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death Academic Article
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Adam Meets Eph: An ADAM Substrate Recognition Module Acts as a Molecular Switch for Ephrin Cleavage In trans Academic Article
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Allelic polymorphism in the T cell receptor and its impact on immune responses Academic Article
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An FcγRIIa-binding peptide that mimics the interaction between FcγRIIa and IgG Academic Article
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Analysis of Fasciola cathepsin L5 by S2 subsite substitutions and determination of the P1–P4 specificity reveals an unusual preference Academic Article
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Analysis of PrP conformation using circular dichroism. Academic Article
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Angiotensinogen cleavage by renin: importance of a structurally constrained N-terminus Academic Article
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Anionic Phospholipid Interactions of the Prion Protein N Terminus Are Minimally Perturbing and Not Driven Solely by the Octapeptide Repeat Domain Academic Article
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Apoptotic pore formation is associated with in-plane insertion of Bak or Bax central helices into the mitochondrial outer membrane Academic Article
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Architecture of Eph receptor clusters Academic Article
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Aromatic Anchor at an Invariant Hormone-Receptor Interface FUNCTION OF INSULIN RESIDUE B24 WITH APPLICATION TO PROTEIN DESIGN Academic Article
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Aromatic residues in the C-terminal helix of human apoC-I mediate phospholipid interactions and particle morphology Academic Article
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Assignment of 1H, 13C and 15N resonances of domain III of the ectodomain of apical membrane antigen 1 from Plasmodium falciparum [5] Academic Article
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Atomic structure of granulin determined from native nanocrystalline granulovirus using an X-ray free-electron laser Academic Article
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Bicarbonate-Mediated Stimulation of RegA, the Global Virulence Regulator from Citrobacter rodentium Academic Article
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Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin-lipid oligomeric assemblies and membrane permeabilization Academic Article
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Biochemical and Structural Insights into Doublecortin-like Kinase Domain 1 Academic Article
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Bioinformatic approaches for predicting substrates of proteases Academic Article
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Buffy, a Drosophila Bcl-2 protein, has anti-apoptotic and cell cycle inhibitory functions Academic Article
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CR1/CR2 Interactions Modulate the Functions of the Cell Surface Epidermal Growth Factor Receptor Academic Article
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Caenorhabditis elegans NONO-1: Insights into DBHS protein structure, architecture, and function Academic Article
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Calcium-dependent oligomerization of CAR proteins at cell membrane modulates ABA signaling Academic Article
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Can cyclic HIV protease inhibitors bind in a non-preferred form? An ab initio, DFT and MM-PB(GB)SA study Academic Article
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Changes in snoRNA and snRNA Abundance in the Human, Chimpanzee, Macaque, and Mouse Brain Academic Article
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Chaperonin 60 and mitochondrial disease in Dictyostelium Academic Article
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Characterization of TCTP, the Translationally Controlled Tumor Protein, from Arabidopsis thaliana Academic Article
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Characterization of bovine heparin-binding neurotrophic factor (HBNF): Assignment of disulfide bonds Academic Article
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Characterization of monomeric dihydrodipicolinate synthase variant reveals the importance of substrate binding in optimizing oligomerization Academic Article
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Cleaved antitrypsin polymers at atomic resolution Academic Article
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Comparative Sequence, Structure and Redox Analyses of Klebsiella pneumoniae DsbA Show That Anti-Virulence Target DsbA Enzymes Fall into Distinct Classes Academic Article
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Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer Academic Article
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Conformational detection of prion protein with biarsenical labeling and FlAsH fluorescence Academic Article
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Conservation of structural motifs and antigenic diversity in the Plasmodium falciparum merozoite surface protein-3 (MSP-3)1Note: Nucleotide sequence data reported in this manuscript are available in the EMBL, GenBank™ and DDJB data bases under the accession numbers L07944, L28825, U08851 and U08852.1 Academic Article
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CopC Protein fromPseudomonassyringae: Intermolecular Transfer of Copper from Both the Copper(I) and Copper(II) Sites Academic Article
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Copper and Zinc Binding Modulates the Aggregation and Neurotoxic Properties of the Prion Peptide PrP106−126† Academic Article
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Crystal Structure and Comparative Functional Analyses of a Mycobacterium Aldo-Keto Reductase Academic Article
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Crystal Structure of a BCL-W Domain-Swapped Dimer: Implications for the Function of BCL-2 Family Proteins Academic Article
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Crystal structure and immunological properties of the first annexin fromSchistosoma mansoni: insights into the structural integrity of the schistosomal tegument Academic Article
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Crystal structure of auracyanin, a “blue” copper protein from the green thermophilic photosynthetic bacterium Chloroflexus aurantiacus11Edited by R Huber Academic Article
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Crystal structure of the Leishmania major
MIX protein: A scaffold protein that mediates protein-protein interactions Academic Article
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Delineating common molecular mechanisms in Alzheimer's and prion diseases Academic Article
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Design principles of peptide based self-assembled nanomaterials Chapter
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Dimerization of Bacterial Diaminopimelate Epimerase Is Essential for Catalysis Academic Article
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Diverse functions of mitochondrial AAA+ proteins: protein activation, disaggregation, and degradationThis paper is one of a selection of papers published in this special issue entitled 8th International Conference on AAA Proteins and has undergone the Journal's usual peer review process. Academic Article
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Dopamine and the Dopamine Oxidation Product 5,6-Dihydroxylindole Promote Distinct On-Pathway and Off-Pathway Aggregation of α-Synuclein in a pH-Dependent Manner Academic Article
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Dopamine promotes α‐synuclein aggregation into SDS‐resistant soluble oligomers via a distinct folding pathway Academic Article
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EGCG disaggregates amyloid-like fibrils formed by Plasmodium falciparum merozoite surface protein 2 Academic Article
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EcxAB is a founding member of a new family of metalloprotease AB5 toxins with a hybrid cholera-like B subunit. Academic Article
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Effect of Oxidation and Mutation on the Conformational Dynamics and Fibril Assembly of Amyloidogenic Peptides Derived from Apolipoprotein C-II Academic Article
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Effect of pH and denaturants on the folding and stability of murine interleukin-6 Academic Article
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Evaluation of Diverse α/β-Backbone Patterns for Functional α-Helix Mimicry: Analogues of the Bim BH3 Domain Academic Article
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Exploring ligand recognition, selectivity and dynamics of TPR domains of chloroplast Toc64 and mitochondria Om64 from Arabidopsis thaliana Academic Article
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Focus on Molecules: Melanopsin Academic Article
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Formation of a High Affinity Lipid-Binding Intermediate during the Early Aggregation Phase of α-Synuclein† Academic Article
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Functional implications of modifying RyR-activating peptides for membrane permeability Academic Article
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GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop Academic Article
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Generating recombinant C-terminal prion protein fragments of exact native sequence Academic Article
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Geometrically Precise Building Blocks: the Self-Assembly of beta-Peptides Academic Article
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Glycosaminoglycan sulfation determines the biochemical properties of prion protein aggregates Academic Article
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High-Resolution Structural Characterization of a Helical α/β-Peptide Foldamer Bound to the Anti-Apoptotic Protein Bcl-xL Academic Article
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Higher-Resolution Structure of the Human Insulin Receptor Ectodomain: Multi-Modal Inclusion of the Insert Domain Academic Article
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Highly Divergent T-cell Receptor Binding Modes Underlie Specific Recognition of a Bulged Viral Peptide bound to a Human Leukocyte Antigen Class I Molecule Academic Article
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How insulin engages its primary binding site on the insulin receptor Academic Article
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Human Erythrocyte Band 7.2b Is Preferentially Labeled by a Photoreactive Phospholipid Academic Article
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ILQINS Hexapeptide, Identified in Lysozyme Left-Handed Helical Ribbons and Nanotubes, Forms Right-Handed Helical Ribbons and Crystals Academic Article
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Identification of Active-Site Residues of the Pro-Metastatic Endoglycosidase Heparanase† Academic Article
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Identification of an amyloid fibril forming peptide comprising residues 46-59 of apolipoprotein A-I Academic Article
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Identification of the bona fide DHDPS from a common plant pathogen Academic Article
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Import-Associated Translational Inhibition: Novel In Vivo Evidence for Cotranslational Protein Import into Dictyostelium discoideum Mitochondria Academic Article
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Insights into Duffy Binding-like Domains through the Crystal Structure and Function of the Merozoite Surface Protein MSPDBL2 from Plasmodium falciparum* Academic Article
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Interleukin-6: Structure-function relationships Academic Article
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Intracellular Trafficking of the KV1.3 Potassium Channel Is Regulated by the Prodomain of a Matrix Metalloprotease Academic Article
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Introduction of a Mutation in the Shutter Region of Antithrombin (Phe77 → Leu) Increases Affinity for Heparin and Decreases Thermal Stability† Academic Article
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Kinetic and Structural Analysis of MutantEscherichia coliDihydroorotases: A Flexible Loop Stabilizes the Transition State†,‡ Academic Article
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Lactam-Stabilized Helical Analogues of the Analgesic μ-Conotoxin KIIIA Academic Article
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Ligand Recognition by the TPR Domain of the Import Factor Toc64 from Arabidopsis thaliana Academic Article
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Mapping a conserved conformational epitope from the M protein of group a streptococci Academic Article
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Mechanism of Membrane Interaction and Disruption by α-Synuclein Academic Article
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Mechanism of intersubunit ketosynthase–dehydratase interaction in polyketide synthases Academic Article
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Membrane core-specific antimicrobial action of Cathelicidin LL-37 peptide switches between pore and nanofibre formation Academic Article
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Methods to Measure the Kinetics of Protease Inhibition by Serpins Academic Article
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Minimal requirements for actin filament disassembly revealed by structural analysis of malaria parasite actin-depolymerizing factor 1 Academic Article
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Modelling the structure of the fusion protein from human respiratory syncytial virus Academic Article
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Molecular cloning of a gene encoding an arabinogalactan-protein from pear (Pyrus communis) cell suspension culture. Academic Article
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Mutation to bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosis Academic Article
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Necroptosis signalling is tuned by phosphorylation of MLKL residues outside the pseudokinase domain activation loop Academic Article
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New method for purifying histidine-rich glycoprotein from human plasma redefines its functional properties Academic Article
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Novel insights on the mechanism of action of α-amylase inhibitors from the plant defensin family Academic Article
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O-Glycosylated Cell Wall Proteins Are Essential in Root Hair Growth Academic Article
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Phospholipid Interaction Induces Molecular-level Polymorphism in Apolipoprotein C-II Amyloid Fibrils via Alternative Assembly Pathways Academic Article
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Physical characterization of serpin conformations Academic Article
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Physicochemical Characterization of an Antagonistic Human Interleukin-6 Dimer† Academic Article
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PinA from Aspergillus nidulans binds to pS/pT-P motifs using the same Loop I and XP groove as mammalian Pin1 Academic Article
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Pollen Tubes of Nicotiana alata Express Two Genes from Different β-Glucan Synthase Families Academic Article
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Polyalanine expansions drive a shift into alpha-helical clusters without amyloid-fibril formation Academic Article
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Predicting serpin/protease interactions Academic Article
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Preprotein Translocase of the Outer Mitochondrial Membrane: Reconstituted Tom40 Forms a Characteristic TOM Pore Academic Article
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Probing the structure of Leishmania major DHFR TS and structure based virtual screening of peptide library for the identification of anti-leishmanial leads Academic Article
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Properties of the Thioredoxin Fold Superfamily Are Modulated by a Single Amino Acid Residue Academic Article
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Protective Efficacy of Cross-Reactive CD8+ T Cells Recognising Mutant Viral Epitopes Depends on Peptide-MHC-I Structural Interactions and T Cell Activation Threshold Academic Article
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Protein unfolding is essential for cleavage within the alpha-helix of a model protein substrate by the serine protease, thrombin Academic Article
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Relaxin-like bioactivity of ovine Insulin 3 (INSL3) analogues Academic Article
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Requirement of multiple phage displayed peptide libraries for optimal mapping of a conformational antibody epitope on CCR5 Academic Article
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Research on the Tomato Metacaspase Protein Interactions with Ca~2+ by Spectroscopy and Molecular Probe Academic Article
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Residue-Based Preorganization of BH3-Derived α/β-Peptides: Modulating Affinity, Selectivity and Proteolytic Susceptibility in α-Helix Mimics Academic Article
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Reversible Conversion of Monomeric Human Prion Protein Between Native and Fibrilogenic Conformations Academic Article
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Rv2969c, essential for optimal growth inMycobacterium tuberculosis, is a DsbA-like enzyme that interacts with VKOR-derived peptides and has atypical features of DsbA-like disulfide oxidases Academic Article
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Selective Removal of Individual Disulfide Bonds within a Potato Type II Serine Proteinase Inhibitor from Nicotiana alata Reveals Differential Stabilization of the Reactive-Site Loop Academic Article
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Sent packing: Protein engineering generates a new crystal form of Pseudomonas aeruginosa DsbA1 with increased catalytic surface accessibility Academic Article
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Serpins 2005 - fun between the β-sheets Academic Article
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Serpins in theCaenorhabditis elegans genome Academic Article
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Serpins: Finely Balanced Conformational Traps Academic Article
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Signals Required for the Import and Processing of the Alternative Oxidase into Mitochondria Academic Article
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Solution Conformation, Backbone Dynamics and Lipid Interactions of the Intrinsically Unstructured Malaria Surface Protein MSP2 Academic Article
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Solution structure of a baculoviral inhibitor of apoptosis (IAP) repeat Academic Article
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Solution structure of synthetic peptides corresponding to the C-terminal helix of interleukin-6 Academic Article
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Solution structures by 1 H NMR of the novel cyclic trypsin inhibitor SFTI-1 from sunflower seeds and an acyclic permutant 1 1Edited by M. F. Summers Academic Article
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Stabilizing the Pro-Apoptotic BimBH3 Helix (BimSAHB) Does Not Necessarily Enhance Affinity or Biological Activity Academic Article
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Structural Basis of Bcl-xL Recognition by a BH3-Mimetic α/β-Peptide Generated by Sequence-Based Design Academic Article
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Structural Refinement of Insecticidal Plant Proteinase Inhibitors from Nicotiana alata Academic Article
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Structural analysis of phosphorylation-associated interactions of human MCC with Scribble PDZ domains Academic Article
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Structural and Biochemical Characterization of the Oxidoreductase NmDsbA3 from Neisseria meningitidis Academic Article
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Structural and Biological Characterization of Murine-Human Interleukin-6 Chimeras Conference Paper
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Structural and Functional Characterization of Three DsbA Paralogues from Salmonella enterica Serovar Typhimurium* Academic Article
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Structural and functional characterization of the mitochondrial complex IV assembly factor Coa6 Academic Article
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Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responses Academic Article
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Structural biology of the Bcl-2 family and its mimicry by viral proteins Academic Article
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Structural insights into BCL2 pro-survival protein interactions with the key autophagy regulator BECN1 following phosphorylation by STK4/MST1 Academic Article
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Structural insights into a new homodimeric self‐activated GTPase family Academic Article
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Structural requirements for the interaction of sheep insulin-like factor 3 with relaxin receptors in rat atria Academic Article
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Structural resolution of a tandem hormone-binding element in the insulin receptor and its implications for design of peptide agonists Academic Article
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Structural, kinetic and computational investigation of Vitis vinifera DHDPS reveals new insight into the mechanism of lysine-mediated allosteric inhibition Academic Article
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Structure and Function of DsbA, a Key Bacterial Oxidative Folding Catalyst Academic Article
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Structure and Inter-domain Interactions of Domain II from the Blood-stage Malarial Protein, Apical Membrane Antigen 1 Academic Article
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Structure determination and analysis of a haemolytic gingipain adhesin domain from Porphyromonas gingivalis Academic Article
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Structure of the Analgesic μ-Conotoxin KIIIA and Effects on the Structure and Function of Disulfide Deletion†‡ Academic Article
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Structure of the BH3 Domains from the p53-Inducible BH3-Only Proteins Noxa and Puma in Complex with Mcl-1 Academic Article
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Structure ofEscherichia coliaminopeptidase P in complex with the inhibitor apstatin Academic Article
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Structure ofPetunia hybridaDefensin 1, a Novel Plant Defensin with Five Disulfide Bonds† Academic Article
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Synthesis and Structure Determination by NMR of a Putative Vacuolar Targeting Peptide and Model of a Proteinase Inhibitor fromNicotiana alata†,‖ Academic Article
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Synthesis of Stapled β3-Peptides through Ring-Closing Metathesis Academic Article
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Targeted Delivery of an ssrA-Tagged Substrate by the Adaptor Protein SspB to Its Cognate AAA+ Protein ClpX Academic Article
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The Assembly of Individual Chaplin Peptides from Streptomyces coelicolor into Functional Amyloid Fibrils Academic Article
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The BECN1 N-terminal domain is intrinsically disordered Academic Article
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The Disulfide Bond Arrangement of Leukemia Inhibitory Factor: Homology to Oncostatin M and Structural Implications Academic Article
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The High Resolution Crystal Structure of the Human Tumor Suppressor Maspin Reveals a Novel Conformational Switch in the G-helix Academic Article
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The Interaction of Bioactive Peptides with an Immobilized Phosphatidylcholine Monolayer Academic Article
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The Kinetics of Amyloid Fibrillar Aggregation of Uperin 3.5 Is Directed by the Peptide’s Secondary Structure Academic Article
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The Murine Orthologue of Human Antichymotrypsin Academic Article
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The Propeptide of the Transforming Growth Factor-β Superfamily Member, Macrophage Inhibitory Cytokine-1 (MIC-1), Is a Multifunctional Domain That Can Facilitate Protein Folding and Secretion Academic Article
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The Single Mutation Phe173 → Ala Induces a Molten Globule-like State in Murine Interleukin-6† Academic Article
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The Structure of SOCS3 Reveals the Basis of the Extended SH2 Domain Function and Identifies an Unstructured Insertion That Regulates Stability Academic Article
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The Structure of the Atypical Killer Cell Immunoglobulin-like Receptor, KIR2DL4 Academic Article
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The Three-dimensional Solution Structure by 1H NMR of a 6-Kda Proteinase Inhibitor Isolated from the Stigma of Nicotiana alata Academic Article
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The WD40 Protein BamB Mediates Coupling of BAM Complexes into Assembly Precincts in the Bacterial Outer Membrane Academic Article
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The X-ray Crystal Structure of Full-Length Human Plasminogen Academic Article
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The antigen 43 structure reveals a molecular Velcro-like mechanism of autotransporter-mediated bacterial clumping Academic Article
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The defensins consist of two independent, convergent protein superfamilies Academic Article
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The evolution, function and mechanisms of action for plant defensins Academic Article
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The role of strand 1 of the C β-sheet in the structure and function of α1-antitrypsin Academic Article
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The solution structure of C1-T1, a two-domain proteinase inhibitor derived from a circular precursor protein from Nicotiana alata11Edited by P. E. Wright Academic Article
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The three-dimensional structural surface of two beta-sheet scorpion toxins mimics that of an alpha-helical dihydropyridine receptor segment Academic Article
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The trans-Golgi network GRIP-domain proteins form α-helical homodimers Academic Article
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Trifluoroethanol induces the self-association of specific amphipathic peptides Academic Article
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Unique structural features of a bacterial autotransporter adhesin suggest mechanisms for interaction with host macromolecules Academic Article
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Unzipping the role of chirality in nanoscale self-assembly of tripeptide hydrogels Academic Article