subject area of

• A Multiple Protease Strategy to Optimise the Shotgun Proteomics of Mature Medicinal Cannabis Buds  Academic Article
• A multi-step peptidolytic cascade for amino acid recovery in chloroplasts  Academic Article
• AKP-11 - A novel S1P1 agonist with favorable safety profile attenuates experimental autoimmune encephalomyelitis in rat model of multiple sclerosis  Academic Article
• An Ancient Peptide Family Buried within Vicilin Precursors  Academic Article
• CLL cells are resistant to smac mimetics because of an inability to form a ripoptosome complex.  Academic Article
• CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity  Academic Article
• Ca2+-dependent proteolysis of junctophilin-1 and junctophilin-2 in skeletal and cardiac muscle  Academic Article
• Colon tumour secretopeptidome: Insights into endogenous proteolytic cleavage events in the colon tumour microenvironment  Academic Article
• Comparative 2D DIGE analysis of the depleted serum proteome for biomarker discovery  Academic Article
• Control of Protein Function through Regulated Protein Degradation: Biotechnological and Biomedical Applications  Academic Article
• CrmA orthologs from diverse poxviruses potently inhibit caspases-1 and -8, yet cleavage site mutagenesis frequently produces caspase-1-specific variants  Academic Article
• Cytokine receptor signaling activates an IKK-dependent phosphorylation of PUMA to prevent cell death  Academic Article
• Determining Degradation and Synthesis Rates ofArabidopsisProteins Using the Kinetics of Progressive15N Labeling of Two-dimensional Gel-separated Protein Spots  Academic Article
• Divalent metal binding by histidine-rich glycoprotein differentially regulates higher order oligomerisation and proteolytic processing  Academic Article
• Global Survey of the Bovine Salivary Proteome: Integrating Multidimensional Prefractionation, Targeted, and Glycocapture Strategies  Academic Article
• Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium falciparum to artemisinins  Academic Article
• Increased S-Nitrosylation and Proteasomal Degradation of Caspase-3 during Infection Contribute to the Persistence of Adherent Invasive Escherichia coli (AIEC) in Immune Cells  Academic Article
• LON is the master protease that protects against protein aggregation in human mitochondria through direct degradation of misfolded proteins  Academic Article
• Machines of Destruction – AAA+ Proteases and the Adaptors That Control Them  Chapter
• Mitochondrial quality control and communications with the nucleus are important in maintaining mitochondrial function and cell health  Academic Article
• Molecular Determinants of the Substrate Specificity of the Complement-initiating Protease, C1r  Academic Article
• Molecular and structural insights into an asymmetric proteolytic complex (ClpP1P2) from Mycobacterium smegmatis  Academic Article
• NEMF mutations that impair ribosome-associated quality control are associated with neuromuscular disease  Academic Article
• Nedd4 family interacting protein 1 (Ndfip1) is required for ubiquitination and nuclear trafficking of BRCA1-associated ATM activator 1 (BRAT1) during the DNA damage response  Academic Article
• N‐degron specificity of chloroplast ClpS1 in plants  Academic Article
• Organellar oligopeptidase (OOP) provides a complementary pathway for targeting peptide degradation in mitochondria and chloroplasts  Academic Article
• POSH regulates Hippo signaling through ubiquitin-mediated expanded degradation  Academic Article
• PROSPERous: high-throughput prediction of substrate cleavage sites for 90 proteases with improved accuracy  Academic Article
• Pathogenic mutations within the hydrophobic domain of the prion protein lead to the formation of protease-sensitive prion species with increased lethality  Academic Article
• Predicting serpin/protease interactions  Academic Article
• Preface  Conference Paper
• Protein unfolding is essential for cleavage within the alpha-helix of a model protein substrate by the serine protease, thrombin  Academic Article
• Proteolytic Regulation of Stress Response Pathways in Escherichia coli  Chapter
• Pupylation of PafA or Pup inhibits components of the Pup-Proteasome system  Academic Article
• Serglycin determines secretory granule repertoire and regulates natural killer cell and cytotoxic T lymphocyte cytotoxicity  Academic Article
• Standard and immunoproteasomes show similar peptide degradation specificities  Editorial Article
• Structural Basis for Regulated Proteolysis by the α-Secretase ADAM10  Academic Article
• Sulindac modulates secreted protein expression from LIM1215 colon carcinoma cells prior to apoptosis  Academic Article
• Surfaceome of exosomes secreted from the colorectal cancer cell line SW480: Peripheral and integral membrane proteins analyzed by proteolysis and TX114  Academic Article
• The Direct Molecular Target for Imipridone ONC201 Is Finally Established  Editorial Article
• The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation  Academic Article
• The N-end rule adaptor protein ClpS from Plasmodium falciparum exhibits broad substrate specificity  Academic Article
• The N-end rule pathway: From recognition by N-recognins, to destruction by AAA+proteases  Academic Article
• The Role of AAA+ Proteases in Mitochondrial Protein Biogenesis, Homeostasis and Activity Control  Chapter
• Transformed MDCK cells secrete elevated MMP1 that generates LAMA5 fragments promoting endothelial cell angiogenesis  Academic Article
• Transition State Mimetics of the Plasmodium Export Element Are Potent Inhibitors of Plasmepsin V from P-falciparum and P-vivax  Academic Article
• Understanding the Pro/N-end rule pathway  Academic Article
• Unfolded protein responses in bacteria and mitochondria: A central role for the ClpXP machine  Academic Article
• X-ray Crystal Structure and Specificity of the Plasmodium falciparum Malaria Aminopeptidase PfM18AAP  Academic Article
• XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation  Academic Article
• alpha/beta-Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity in Living Cells  Academic Article