subject area of

• A Cyclic Nucleotide Sensitive Promoter Reporter System Suitable for Bacteria and Plant Cells  Academic Article
• A Mitochondrial LYR Protein is Required for Complex I Assembly  Academic Article
• A Randomized Phase II/III Study of Dalotuzumab in Combination With Cetuximab and Irinotecan in Chemorefractory, KRAS Wild-Type, Metastatic Colorectal Cancer  Academic Article
• A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells.  Academic Article
• A putative Arabidopsis thaliana glycosyltransferase, At4g01220, which is closely related to three plant cell wall-specific xylosyltransferases, is differentially expressed spatially and temporally  Academic Article
• Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide  Academic Article
• Activin and NADPH-oxidase in preeclampsia: Insights from in vitro and murine studies  Academic Article
• All-Trans-Retinoic Acid Enhances Mitochondrial Function in Models of Human Liver  Academic Article
• Alterations in neuronal metabolism contribute to the pathogenesis of prion disease  Academic Article
• Altered N-methyl-d-aspartate receptor function in reelin heterozygous mice: Male–female differences and comparison with dopaminergic activity  Academic Article
• Analysis of Ras-induced oncogenic transformation of NIH-3T3 cells using differential-display 2-DE proteomics  Academic Article
• Angiotensin IV-evoked vasoprotection is conserved in advanced atheroma  Academic Article
• Anode Biofilm Transcriptomics Reveals Outer Surface Components Essential for High Density Current Production in Geobacter sulfurreducens Fuel Cells  Academic Article
• Aromatase transgenic upregulation modulates basal cardiac performance and the response to ischemic stress in male mice  Academic Article
• BRAF V600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells  Academic Article
• Bim Links ER Stress and Apoptosis in Cells Expressing Mutant SOD1 Associated with Amyotrophic Lateral Sclerosis  Academic Article
• Butyrate-induced apoptotic cascade in colonic carcinoma cells: Modulation of the β-catenin-Tcf pathway and concordance with effects of sulindac and trichostatin A but not curcumin  Academic Article
• Calsenilin contributes to neuronal cell death in ischemic stroke  Academic Article
• Caspase-14: a new player in cytotrophoblast differentiation  Academic Article
• Cellular Redox Activity of Coenzyme Q 10 : Effect of CoQ 10 Supplementation on Human Skeletal Muscle  Academic Article
• Characterization of Pneumococcal genes involved in bloodstream invasion in a mouse model  Academic Article
• Characterization of a Distinct Population of Circulating Human Non-Adherent Endothelial Forming Cells and Their Recruitment via Intercellular Adhesion Molecule-3  Academic Article
• Clozapine reverses schizophrenia-related behaviours in the metabotropic glutamate receptor 5 knockout mouse: association with N-methyl-d-aspartic acid receptor up-regulation  Academic Article
• Combination therapy with low-dose IVIG and a C1-esterase inhibitor ameliorates brain damage and functional deficits in experimental ischemic stroke  Academic Article
• Conditional Overexpression of Liver Receptor Homolog-1 in Female Mouse Mammary Epithelium Results in Altered Mammary Morphogenesis via the Induction of TGF-β  Academic Article
• Cre transgene results in global attenuation of the cAMP/PKA pathway  Academic Article
• Cross-Talk between Activated Human NK Cells and CD4+T Cells via OX40-OX40 Ligand Interactions  Academic Article
• Decreased expression of GGA3 Protein in Alzheimer's disease frontal cortex and increased co-distribution of BACE with the amyloid precursor protein  Academic Article
• Defining Core Metabolic and Transcriptomic Responses to Oxygen Availability in Rice Embryos and Young Seedlings  Academic Article
• Degradation of the Alzheimer Disease Amyloid β-Peptide by Metal-dependent Up-regulation of Metalloprotease Activity  Academic Article
• Development by environment interactions controlling tryptophan hydroxylase expression  Academic Article
• Differential regulation of Nedd4 ubiquitin ligases and their adaptor protein Ndfip1 in a rat model of ischemic stroke  Academic Article
• Discovery and validation of serum biomarkers expressed over the first twelve weeks of Fasciola hepatica infection in sheep  Academic Article
• Does upregulated host cell receptor expression provide a link between bacterial adhesion and chronic respiratory disease?  Academic Article
• Drosophila SPARC Is a Self-Protective Signal Expressed by Loser Cells during Cell Competition  Academic Article
• EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival  Academic Article
• ER Stress Triggers Apoptosis by Activating BH3-Only Protein Bim  Academic Article
• Effects of chronic sleep deprivation on central cholinergic receptors in rat brain  Academic Article
• Effects of glucosamine on proteoglycan loss by tendon, ligament and joint capsule explant cultures  Academic Article
• Effects of lipopolysaccharide on glial phenotype and activity of glutamate transporters: Evidence for delayed up-regulation and redistribution of GLT-1  Academic Article
• Elevated MMP2 abundance and activity in mdx mice are alleviated by prenatal taurine supplementation  Academic Article
• Engagement of the Signaling Lymphocytic Activation Molecule (SLAM) on Activated T Cells Results in IL-2-Independent, Cyclosporin A-Sensitive T Cell Proliferation and IFN-γ Production  Academic Article
• Exposure to high- and low-light conditions in an open-field test of anxiety increases c-Fos expression in specific subdivisions of the rat basolateral amygdaloid complex  Academic Article
• Expression of the CXCR3 ligand I-TAC by hepatocytes in chronic hepatitis C and its correlation with hepatic inflammation  Academic Article
• Expression profiling of metabolic genes in response to methyl jasmonate reveals regulation of genes of primary and secondary sulfur-related pathways in Arabidopsis thaliana  Academic Article
• Extracellular nucleotide signaling by P2 receptors inhibits IL-12 and enhances IL-23 expression in human dendritic cells: a novel role for the cAMP pathway  Academic Article
• Fra-1 controls motility of bladder cancer cells via transcriptional upregulation of the receptor tyrosine kinase AXL  Academic Article
• Fragile X males with unmethylated, full mutation trinucleotide repeat expansions have elevated levels ofFMR1 messenger RNA  Academic Article
• Functional role of soluble receptor for advanced glycation end products in stroke  Academic Article
• Functional up-regulation of endopeptidase neurolysin during post-acute and early recovery phases of experimental stroke in mouse brain  Academic Article
• Gene expression profiling of intestinal epithelial cell maturation along the crypt-villus axis  Academic Article
• Genomewide mRNA profiling of esophageal squamous cell carcinoma for identification of cancer biomarkers  Academic Article
• Glucose levels are associated with cardiovascular disease and death in an international cohort of normal glycaemic and dysglycaemic men and women: the EpiDREAM cohort study  Academic Article
• HIF1α deficiency reduces inflammation in a mouse model of proximal colon cancer  Academic Article
• HIF1α expression under normoxia in prostate cancer - Which pathways to target?  Academic Article
• Hepatocyte growth factor renders BRAF mutant human melanoma cell lines resistant to PLX4032 by downregulating the pro-apoptotic BH3-only proteins PUMA and BIM  Academic Article
• High Molecular Weight Gingipains from Porphyromonas gingivalis Induce Cytokine Responses from Human Macrophage-Like Cells via a Nonproteolytic Mechanism  Academic Article
• High-throughput sequencing of plasma MicroRNA in chronic fatigue syndrome/myalgic encephalomyelitis  Academic Article
• Histone Deacetylase 3 (HDAC3) and Other Class I HDACs Regulate Colon Cell Maturation and p21 Expression and Are Deregulated in Human Colon Cancer  Academic Article
• Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes  Academic Article
• Human neuroblastoma SH-SY5Y cells show increased resistance to hyperthermic stress after differentiation, associated with elevated levels of Hsp72  Academic Article
• Hydrogen peroxide mediates abscisic acid‐induced HSP 70 accumulation and heat tolerance in grafted cucumber plants  Academic Article
• Hypoxic preconditioning of myoblasts implanted in a tissue engineering chamber significantly increases local angiogenesis via upregulation of myoblast vascular endothelial growth factor-A expression and downregulation of miRNA-1, miRNA-206 and angiopoietin-1  Academic Article
• IL-37 increases in patients after ischemic stroke and protects from inflammatory brain injury, motor impairment and lung infection in mice  Academic Article
• IL-6 trans-signaling modulates TLR4-dependent inflammatory responses via STAT3  Academic Article
• IRF6 regulates the expression of IL-36γ by human oral epithelial cells in response to Porphyromonas gingivalis  Academic Article
• Identification of OsbHLH133 as a regulator of iron distribution between roots and shoots in Oryza sativa  Academic Article
• Identification of novel Ras-cooperating oncogenes in Drosophila melanogaster: A RhoGEF/Rho-family/JNK pathway is a central driver of tumorigenesis  Academic Article
• In Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1-Rok-Myosin-II and JNK signalling  Academic Article
• Induction of the Unfolded Protein Response in Familial Amyotrophic Lateral Sclerosis and Association of Protein-disulfide Isomerase with Superoxide Dismutase 1  Academic Article
• Inhibition of the MAP kinase cascade blocks heregulin-induced cell cycle progression in T-47D human breast cancer cells  Academic Article
• Inhibitor of apoptosis protein (IAP) antagonists demonstrate divergent immunomodulatory properties in human immune subsets with implications for combination therapy  Academic Article
• Intense exercise up-regulates Na+,K+-ATPase isoform mRNA, but not protein expression in human skeletal muscle  Academic Article
• Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function.  Academic Article
• Interleukin-6 promotes pulmonary emphysema associated with apoptosis in mice  Academic Article
• Intestinal adenoma formation and MYC activation are regulated by cooperation between MYB and Wnt signaling  Academic Article
• Intravenous immunoglobulin protects neurons against amyloid beta-peptide toxicity and ischemic stroke by attenuating multiple cell death pathways  Academic Article
• Involvement of gp130-associated cytokine signaling in Müller cell activation following optic nerve lesion  Academic Article
• JRK is a positive regulator of β-catenin transcriptional activity commonly overexpressed in colon, breast and ovarian cancer  Academic Article
• Kaiso-Deficient Mice Show Resistance to Intestinal Cancer  Academic Article
• Lgl regulates notch signaling via endocytosis, independently of the apical aPKC-Par6-Baz polarity complex  Academic Article
• Maintenance of Growth Rate at Low Temperature in Rice and Wheat Cultivars with a High Degree of Respiratory Homeostasis is Associated with a High Efficiency of Respiratory ATP Production  Academic Article
• Maternal exercise in rats upregulates the placental IGF-system with diet and sex-specific responses: minimal effects in mothers born growth restricted  Academic Article
• Megakaryocytes co-localise with hemopoietic stem cells and release cytokines that up-regulate stem cell proliferation  Academic Article
• Mixed Proteasomes Function To Increase Viral Peptide Diversity and Broaden Antiviral CD8+ T Cell Responses  Academic Article
• Molecular and physiological responses during thermal acclimation of leaf photosynthesis and respiration in rice  Academic Article
• NADPH-oxidase activity is elevated in penumbral and non-ischemic cerebral arteries following stroke  Academic Article
• NFκB is a central regulator of protein quality control in response to protein aggregation stresses via autophagy modulation  Academic Article
• Nedd4-WW Domain-Binding Protein 5 (Ndfip1) Is Associated with Neuronal Survival after Acute Cortical Brain Injury  Academic Article
• Nox1 upregulates the function of vascular T-type calcium channels following chronic nitric oxide deficit  Academic Article
• Osteopontin deficiency delays inflammatory infiltration and the onset of muscle regeneration in a mouse model of muscle injury  Academic Article
• Oxaliplatin resistance induced by ERCC1 up-regulation is abrogated by siRNA-mediated gene silencing in human colorectal cancer cells  Academic Article
• Placenta-Derived Soluble MHC Class I Chain-Related Molecules Down-Regulate NKG2D Receptor on Peripheral Blood Mononuclear Cells during Human Pregnancy: A Possible Novel Immune Escape Mechanism for Fetal Survival  Academic Article
• Plasmalogen modulation attenuates atherosclerosis in ApoE- and ApoE/GPx1-deficient mice  Academic Article
• Predicting the presence of oral squamous cell carcinoma using commonly dysregulated MicroRNA in oral swirls  Academic Article
• Preservation of skeletal muscle mitochondrial content in older adults: relationship between mitochondria, fibre type and high-intensity exercise training  Academic Article
• Proapoptotic Bcl-2 family member Bim is involved in the control of mast cell survival and is induced together with Bcl-XL upon IgE-receptor activation  Academic Article
• Protein disulphide isomerase is associated with mutant SOD1 in canine degenerative myelopathy.  Academic Article
• Proteogenomics analysis unveils a TFG-RET gene fusion and druggable targets in papillary thyroid carcinomas  Academic Article
• Proteomic identification of interferon-induced proteins with tetratricopeptide repeats as markers of M1 macrophage polarization  Academic Article
• RNAi-mediated knock-down of arylamine N-acetyltransferase-1 expression induces E-cadherin up-regulation and cell-cell contact growth inhibition  Academic Article
• Repurposed JAK1/JAK2 Inhibitor Reverses Established Autoimmune Insulitis in NOD Mice  Academic Article
• Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4  Academic Article
• Retinal Light Damage: Structural and Functional Effects of the Antioxidant Glutathione Peroxidase-1  Academic Article
• Reversal of Vascular Macrophage Accumulation and Hypertension by a CCR2 Antagonist in Deoxycorticosterone/Salt-Treated Mice  Academic Article
• SIRT2 inhibition confers neuroprotection by downregulation of FOXO3a and MAPK signaling pathways in ischemic stroke  Academic Article
• Selenium supplementation induces mitochondrial biogenesis in trophoblasts  Academic Article
• Sequence analysis and characterisation of virally induced viperin in the saltwater crocodile (Crocodylus porosus)  Academic Article
• Signalling pathways activated by hydrogen peroxide in vascular smooth muscle  Academic Article
• Significantly Elevated FMR1 mRNA and Mosaicism for Methylated Premutation and Full Mutation Alleles in Two Brothers with Autism Features Referred for Fragile X Testing  Academic Article
• Sparse feature selection methods identify unexpected global cellular response to strontium-containing materials  Academic Article
• Sublethal Concentrations of Prion Peptide PrP106–126 or the Amyloid Beta Peptide of Alzheimer's Disease Activates Expression of Proapoptotic Markers in Primary Cortical Neurons  Academic Article
• Sulindac activates NF-κB signaling in colon cancer cells  Academic Article
• Sulphur dioxide evokes a large scale reprogramming of the grape berry transcriptome associated with oxidative signalling and biotic defence responses  Academic Article
• Symplekin promotes tumorigenicity by up-regulating claudin-2 expression  Academic Article
• TRAIL-induced apoptosis is enhanced by heat shock protein 70 expression  Academic Article
• Targeting the upregulation of reactive oxygen species subsequent to hyperglycemia prevents type 1 diabetic cardiomyopathy in mice  Academic Article
• Temperature-dependent sex determination: Upregulation of SOX9 expression after commitment to male development  Academic Article
• Temporal upregulation of host surface receptors provides a window of opportunity for bacterial adhesion and disease  Academic Article
• The CRF1receptor antagonist, antalarmin, reverses isolation-induced up-regulation of dopamine D2receptors in the amygdala and nucleus accumbens of fawn-hooded rats  Academic Article
• The Complement Factor C5a Contributes to Pathology in a Rat Model of Amyotrophic Lateral Sclerosis  Academic Article
• The DNA damage response (DDR) is induced by the C9orf72 repeat expansion in amyotrophic lateral sclerosis  Academic Article
• The Rho kinase inhibitor Fasudil up-regulates astrocytic glutamate transport subsequent to actin remodelling in murine cultured astrocytes  Academic Article
• The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma  Academic Article
• The relationship between CCR6 and its binding partners: Does the CCR6-CCL20 axis have to be extended?  Academic Article
• The role of CaMKII in diabetic heart dysfunction  Academic Article
• The superoxide dismutase mimetic tempol blunts diabetes-induced upregulation of NADPH oxidase and endoplasmic reticulum stress in a rat model of diabetic nephropathy  Academic Article
• Thyroid hormone receptor β2 is strongly up-regulated at all levels of the hypothalamo–pituitary–thyroidal axis during late embryogenesis in chicken  Academic Article
• Transcript levels of the intermediate size or grey zone fragile X mental retardation 1 alleles are raised, and correlate with the number of CGG repeats  Academic Article
• Transient expression of myofibroblast-like cells in rat rib fracture callus  Academic Article
• Transketolase-like 1 ectopic expression is associated with DNA hypomethylation and induces the Warburg effect in melanoma cells  Academic Article
• Two novel Venturia inaequalis genes induced upon morphogenetic differentiation during infection and in vitro growth on cellophane  Academic Article
• Upexpression of BHLHE40 in gastric epithelial cells increases CXCL12 production through interaction with p-STAT3 in Helicobacter pylori-associated gastritis  Academic Article
• scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila  Academic Article
• β-Adrenoceptor stimulation upregulates cardiac expression of galectin-3 and BIM through the Hippo signalling pathway.  Academic Article
• β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells  Academic Article