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Professor Weisan Chen Professor of Immunology, Biochemistry

Dr Chen was awarded an NHMRC Visiting Postgraduate Scholarship for Higher Degree in 1989. After acquiring his PhD in Immunology at the Flinders University of Adelaide, Australia, He was awarded with a CJ Martin fellowship from NHMRC and took a postdoctoral position at the National Institutes of Health (NIH), Bethesda, Maryland, USA in the laboratory of Drs Yewdell and Bennink. At the NIH, Dr Chen continued his studies on the mechanisms of antigen processing/presentation, immunodominance and CD8+ T cell epitope selection. During this time, Dr Chen discovered the 11th influenza A virus gene product. He returned to Australia in 2001 to establish his independent T cell Laboratory at the Ludwig Institute, Melbourne and was soon awarded a Wellcome senior international research fellowship from Wellcome Trust, UK. In this position, he expanded his research to include translational tumor immunology and cancer vaccine. Dr Chen’s lab is currently focusing on innate immune cell and T cell responses to influenza A virus. More specifically, the initiation and maintenance of anti-viral T cell response in murine models; antigen cross-presentation, immunodominance and regulatory T cells and their function in anti-viral immunity in humans. Dr Chen’s lab is also actively involved in anti-tumour immunity and vaccine development.

Dr Chen has been a member of NHMRC and Cancer council grant review panels, a frequent reviewer for >30 international journals and many international funding agencies. He has published more than 130 articles. Dr Chen currently A Chief Investigator on the NHMRC influenza program including Nobel Laureate Professor Peter Doherty.

Dr Chen relocated his T cell lab to LIMS in 2012 to take up a position as Professor of Immunology.

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