La Trobe University homepage

Dr

Lesley Cheng Sim

Associate Professor

Biochemistry & Chemistry

RESEARCH INTERESTS

• Developing diagnostic biomarkers and blood-based tests for neurodegenerative diseases and other conditions
• The role of extracellular vesicles in neurodegenerative diseases
• Capturing and characterising subpopulations of extracellular vesicles in biological fluids which can be applied to various types of samples
• Understanding the content and uptake of extracellular vesicles in the brain that could be applied to improve therapeutic delivery to the brain
• Understanding how extracellular vesicles can cross the blood brain barrier to the periphery

FUNDED RESEARCH

  • Showing page 1 out of 1
Showing page 1, funded research 1 to 4 of 4
  • GRANT
    Customised exosomes – the future of regenerative medicine
    Cooperative Research Centres Projects (CRC-P)16 Jan 2023 - 31 Dec 2025
  • COLLABORATIVE RESEARCH
    Optimising the Workflow for miRNA Biomarker Analysis using Izon Columns
    Izon Science Ltd1 Oct 2022 - 31 May 2023
  • GRANT
    Profiling serum derived exosome-associated miRNA as a diagnostic tool for prion disease
    Creutzfeldt-Jakob Disease Support Group-Memorial Award 2019 (in memory of Adrian1 Jan 2019 - 31 Dec 2019
  • GRANT
    Detecting brain specific exosomal miRNA for the diagnosis of Alzheimer's disease
    Dementia Collaborative Research Centre - Assessment and Better Care1 Jul 2016 - 30 Jun 2017